Conditions: Cocaine Dependence, in Remission; Cocaine Abuse, in Remission; Cocaine-Related Disorders Intervention: Drug: Clavulanic Acid Sponsors: Temple University; National Institute on Drug Abuse (NIDA) Recruiting
Condition: Chronic Low-back Pain Interventions: Behavioral: Mindfulness-based dance/movement therapy (M-DMT); Behavioral: Chronic pain social support group Sponsors: Drexel University; National Center for Complementary and Integrative Health (NCCIH); Stony Brook University Recruiting
Conditions: Inflammatory Bowel Disease; Behavioral Symptoms Interventions: Other: TEAM; Other: TECH Sponsors: University of Pittsburgh; Mount Sinai Hospital, New York; The Cleveland Clinic; Patient-Centered Outcomes Research Institute Not yet recruiting
Condition: Heart Failure Interventions: Other: Mobile Health Technology Platform; Other: Usual care Sponsors: University of Pittsburgh; Agency for Healthcare Research and Quality (AHRQ) Not yet recruiting
Conditions: Nightmares; Stress Disorders, Post-Traumatic; Actigraphy; Respiratory Sinus Arrhythmia; Veterans Interventions: Behavioral: Exposure, Relaxation, and Rescripting Therapy; Behavioral: Sleep and Nightmare Management Sponsor: VA Office of Research and Development Not yet recruiting
Conditions: Family Members of: Newborns Extremely Premature; Family Members of: New Pediatric Oncology Patients; Family Members of: Critical Congenital Heart Defect Patients; Family Members of: Children Severe Neurological Impairment Intervention: Sponsors: Children's Hospital of Philadelphia; Cigna Foundation Enrolling by invitation
Conditions: Substance Use Disorders; Opiate Dependence; Opiate Withdrawal Syndrome; Opioid-use Disorder; Alcohol Withdrawal; Alcohol Abuse; Alcohol Use Disorder; Cocaine Abuse; Cocaine Use Disorder; Cocaine Withdrawal; Benzodiazepine Abuse; Benzodiazepine Dependence; Substance Abuse; Heroin Overdoses; Heroin Withdrawal; Heroin Abuse Interventions: Behavioral: Six Step Model of Self-Forgiveness; Behavioral: Treatment as Usual (TAU) Sponsors: University of Pittsburgh; Indiana University of Pennsylvania Not yet recruiting
Conditions: Body Weight; Healthy Diet; Physical Activity; Health Behavior; Healthy Aging Intervention: Behavioral: MOVE UP Sponsors: University of Pittsburgh; Centers for Disease Control and Prevention Not yet recruiting
Condition: Upper Extremity Paresis Intervention: Device: transcranial direct current stimulation Sponsors: University of the Sciences in Philadelphia; Chapman University; Moss Rehabilitation Research Institute; Thomas Jefferson University Recruiting
Conditions: Body Weight; Diet, Healthy; Physical Disability Intervention: Behavioral: MOVE UP Sponsors: University of Pittsburgh; Centers for Disease Control and Prevention Recruiting
Conditions: Sleep; Obstructive Sleep Apnea; Insomnia Intervention: Behavioral: Behavioral Intervention Sponsors: University of Pittsburgh; National Heart, Lung, and Blood Institute (NHLBI) Enrolling by invitation
Conditions: Overweight and Obesity; Physical Activity; Weight Change, Body; Eating Behavior Interventions: Behavioral: Intervention group; Behavioral: Control group Sponsors: Penn State University; National Heart, Lung, and Blood Institute (NHLBI); Arizona State University Completed
Conditions: Adherence, Patient; Motivation; Satisfaction Interventions: Other: Virtual walking trails; Other: Standard of care Sponsor: Thomas Jefferson University Active, not recruiting
Condition: Diabetes Mellitus Interventions: Behavioral: IMPaCT Community Health Worker; Behavioral: Digital health monitoring with financial incentives; Other: Usual Care Sponsors: University of Pennsylvania; The Commonwealth Fund Recruiting
Condition: Nonunion of Fracture Intervention: Diagnostic Test: Next-generation sequencing of swabs collected during surgery Sponsor: Rothman Institute Orthopaedics Enrolling by invitation
Condition: COPD Intervention: Device: nasal delivery of heated and humidified air Sponsors: Frank C Sciurba; Fisher and Paykel Healthcare Not yet recruiting
Condition: Breast Cancer Interventions: Behavioral: Intimacy Enhancement; Behavioral: Living Healthy Together Sponsors: Fox Chase Cancer Center; National Cancer Institute (NCI) Recruiting
Condition: Lung Cancer Interventions: Other: Best Practice; Behavioral: Cancer Educational Materials; Other: Behavioral, Psychological or Informational Intervention; Other: Counseling Sponsor: Thomas Jefferson University Not yet recruiting
Conditions: Pain, Postoperative; Opioid Use Interventions: Drug: Acetaminophen; Drug: Placebo; Drug: Ibuprofen Sponsor: Milton S. Hershey Medical Center Not yet recruiting
Condition: Anorexia Nervosa Interventions: Behavioral: Cognitive Remediation Therapy; Behavioral: Family Based Treatment Sponsor: Children's Hospital of Philadelphia Not yet recruiting
Condition: Feeding Behavior Interventions: Other: Plain Vegetables Served in 100% Portion Size; Other: Plain Vegetables Served in 200% Portion Size; Other: Enhanced Vegetables Served in 100% Portion Size; Other: Enhanced Vegetables Served in 200% Portion Size Sponsors: Penn State University; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Recruiting
Conditions: Granulomatosis With Polyangiitis; Wegener Granulomatosis Intervention: Drug: Trimethoprim Sulfamethoxazole Sponsor: University of Pennsylvania Recruiting
Conditions: Functional Capacity; Physical Activity; Rehabilitation Intervention: Diagnostic Test: Six Minute Walk Test Sponsor: Concordia University, St. Paul Completed
Conditions: Ostomy; Quality of Life; Telehealth Intervention: Behavioral: Ostomy Self-Management Training Sponsors: University of Pennsylvania; National Cancer Institute (NCI) Not yet recruiting
Condition: Strategy Training Interventions: Behavioral: Strategy Training; Other: Enhanced Usual Care Sponsors: University of Pittsburgh; National Institutes of Health (NIH); National Institute on Aging (NIA) Not yet recruiting
Conditions: Stroke, Complication; Stroke; Stroke Sequelae; Hemiparesis; Arm Paralysis Intervention: Device: Cortimo Sponsor: Thomas Jefferson University Recruiting
Conditions: Group Fitness (Traditional); Group Fitness (Game Play-based) Interventions: Behavioral: Group Fitness; Behavioral: PlayFit Sponsors: Milton S. Hershey Medical Center; National Institutes of Health (NIH) Recruiting
Condition: Chronic Pain Intervention: Other: Opioid Taper Pain perception Sponsors: University of Pennsylvania; National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH) Recruiting
Condition: Sleep Intervention: Device: Philips SmartSleep Technology Sponsors: University of Pennsylvania; National Aeronautics and Space Administration (NASA); Philips Healthcare; University of Wisconsin, Madison Recruiting
Condition: Remote Maintenance Training Program Intervention: Behavioral: Wheelchair Maintenance Training Sponsors: University of Pittsburgh; Department of Health and Human Services Recruiting
Condition: Renal Cell Carcinoma Metastatic Interventions: Drug: Abemaciclib; Drug: Sunitinib Sponsors: Milton S. Hershey Medical Center; Eli Lilly and Company Not yet recruiting
Condition: Disability Interventions: Other: pneumatically powered wheelchair or scooter; Device: battery powered wheelchair or scooter Sponsor: VA Office of Research and Development Not yet recruiting
Condition: Migraine Headache With Intractable Migraine Intervention: Drug: ketamine infusion Sponsor: Thomas Jefferson University Enrolling by invitation
Conditions: DNA Damage; Psychological Stress Interventions: Drug: Propranolol; Drug: Placebo oral capsule; Behavioral: Acute stress task; Behavioral: No stress task Sponsors: Dana Bovbjerg; National Cancer Institute (NCI) Recruiting
Conditions: Sleep Fragmentation; Poor Quality Sleep; Nocturia; Nocturnal Enuresis Interventions: Behavioral: Brief behavioral treatment of insomnia (BBTI); Behavioral: Information-only control (IC) Sponsors: University of Pittsburgh; National Institute on Aging (NIA) Recruiting
Condition: Trigger Thumb Intervention: Procedure: Administration of Marcaine without Epinephrine prior to the start of surgery Sponsor: Children's Hospital of Philadelphia Recruiting
Conditions: Healthy Subjects; Functional Dyspepsia; Irritable Bowel Syndrome Intervention: Device: rTMS Sponsors: David Levinthal; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Recruiting
Conditions: Cleft Palate; Tube Disorders Eustachian; Velopharyngeal Incompetence Due to Cleft Palate; Velopharyngeal Insufficiency Interventions: Device: EarPopper; Device: EMST150 Sponsors: Noel Jabbour; National Institute on Deafness and Other Communication Disorders (NIDCD) Not yet recruiting
Condition: Osteopenia Intervention: Diagnostic Test: dual energy x-ray absorptiometry Sponsor: Milton S. Hershey Medical Center Enrolling by invitation
Condition: Autism Spectrum Disorder Intervention: Behavioral: Healthy Habits for Life Sponsors: University of Pittsburgh; Massachusetts General Hospital Not yet recruiting
Conditions: Pain, Postoperative; Satisfaction Intervention: Drug: Ropivacaine Sponsors: Rothman Institute Orthopaedics; Sharpe-Strumia Research Foundation Enrolling by invitation
Conditions: Polycystic Ovary Syndrome; Anovulation; Hyperandrogenism; Insulin Resistance; Glucose Intolerance; Metabolic Complication Interventions: Other: Placebo; Drug: Inositol powder Sponsors: Milton S. Hershey Medical Center; National Center for Complementary and Integrative Health (NCCIH) Not yet recruiting
Conditions: Acute Pain; Surgery; Shoulder Pain Interventions: Device: Auriculotherapy cryopuncture device without nitrogen gas; Device: Auriculotherapy cryopuncture device with nitrogen gas Sponsor: Jacques E. Chelly Not yet recruiting
Condition: Osteochondral Lesion of Talus Interventions: Procedure: Microfracture with Bone Marrow Aspirate Concentrate; Procedure: Microfracture Sponsor: Rothman Institute Orthopaedics Enrolling by invitation
Conditions: Vaccine Hesitancy; Communicable Diseases in Children Interventions: Behavioral: Community Event; Behavioral: Educational Material Sponsors: Milton S. Hershey Medical Center; Merck Sharp & Dohme Corp. Recruiting
Condition: Eustachian Tube Dysfunction Interventions: Device: EarPopper; Device: Tympanometry; Device: Tubomanometry Sponsors: University of Pittsburgh; National Institute on Deafness and Other Communication Disorders (NIDCD) Recruiting
Conditions: HIV-1-infection; Sleep Deprivation; Inflammation Intervention: Behavioral: Sleep deprivation Sponsors: University of Pittsburgh; National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting
Conditions: Drug Overdose; Opioid-Related Disorders Intervention: Device: Diagnostic algorithms that detects/predicts hypoventilation Sponsors: RTM Vital Signs, LLC; Thomas Jefferson University Recruiting
Conditions: Claudication; Peripheral Artery Disease Interventions: Behavioral: DASH Diet plus Home-Based Exercise; Behavioral: Home-Based Exercise Sponsor: Milton S. Hershey Medical Center Not yet recruiting
Condition: Head and Neck Cancer Interventions: Other: Standard of Care Oral Hygiene; Procedure: Oral mucosal deterging and dental prophylaxis Sponsor: Abramson Cancer Center of the University of Pennsylvania Not yet recruiting
Condition: Cardiovascular Diseases Interventions: Behavioral: Aerobic Exercise Group; Behavioral: Physical Activity & Health Information Group Sponsors: University of Pittsburgh; National Institutes of Health (NIH); National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting
Conditions: Pelvic Organ Prolapse; Patient Preparedness Interventions: Other: Preoperative counseling office visit; Other: Preoperative counseling phone call Sponsors: University of Pittsburgh; University of Pittsburgh Medical Center Not yet recruiting
Condition: Osteoarthritis of the Knee Interventions: Behavioral: Social Incentives and Gamification to Promote Exercise; Procedure: Corticosteroid Injection given in A-B order; Behavioral: No Social Incentive applied; Procedure: Corticosteroid Injection given in B-A order Sponsor: VA Office of Research and Development Not yet recruiting
Conditions: Stroke; Spinal Cord Injuries Interventions: Other: Rehabilitation using motorized glove for stroke and spinal cord injury; Other: Functional MRI for stroke and spinal cord injury; Other: Transcranial magnetic stimulation (TMS) for stroke and spinal cord injury Sponsors: VA Pittsburgh Healthcare System; University of Pittsburgh Not yet recruiting
Condition: Automobile Accident Interventions: Behavioral: Weekly feedback; Behavioral: End of intervention period incentive; Behavioral: Loss-framed weekly incentive Sponsors: University of Pennsylvania; U.S. Department of Transportation Federal Highway Administration Enrolling by invitation
Condition: Chronic Kidney Diseases Interventions: Other: Intervention Arm; Other: Usual Care Sponsors: University of Pittsburgh; Vanderbilt University Medical Center; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Not yet recruiting
Conditions: Opiate Addiction; Pregnancy Interventions: Drug: Buprenorphine: Magnitude Group; Drug: Buprenorphine: Interval Group; Drug: Buprenorphine: Dosing Group Sponsors: Steve N. Caritis, MD; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Recruiting
Conditions: Addiction; Opioid-use Disorder Intervention: Device: reSET Sponsors: Milton S. Hershey Medical Center; Columbia University; Research Foundation for Mental Hygiene, Inc. Recruiting
Conditions: Psychosis; Sleep Interventions: Drug: oral melatonin tablets (NatureMade brand); Other: Placebo Sponsors: Children's Hospital of Philadelphia; University of Pennsylvania; Brain and Behavior Research Foundation (NARSAD Young Investigator Award, Grant Number 26742) Recruiting
Conditions: Metastatic Nonsmall Cell Lung Cancer; Non Small Cell Lung Cancer Intervention: Radiation: Stereotactic Body Radiotherapy Sponsors: Crozer-Keystone Health System; Saint Peter's University Hospital, New Brunswick, NJ; Community Medical Center, Toms River, NJ Recruiting
Conditions: Cancer; Advance Care Planning Interventions: Behavioral: In-person, facilitated advance care planning; Behavioral: Web-based advance care planning Sponsors: University of Pittsburgh; National Cancer Institute (NCI) Not yet recruiting
Condition: Opioid Use Interventions: Behavioral: Training; Behavioral: Behavioral economic enhanced arm Sponsors: University of Pennsylvania; American College of Medical Toxicology; Blue Cross Blue Shield Enrolling by invitation
Condition: Lung Cancer Intervention: Other: Educational Intervention Sponsor: Sidney Kimmel Cancer Center at Thomas Jefferson University Active, not recruiting
Condition: Pancreatic Cancer Interventions: Procedure: Endoscopic Retrograde Cholangiopancreatography; Other: Standard of care Sponsor: Sidney Kimmel Cancer Center at Thomas Jefferson University Active, not recruiting
Condition: Acute Otitis Media Interventions: Drug: OP0201 20mg per day+Amoxicillin-clavulanate; Drug: Placebo 0mg per day+Amoxicillin-clavulanate Sponsor: Novus Therapeutics, Inc Recruiting
Conditions: Kidney Transplantation; Hepatitis C Intervention: Drug: sofosbuvir/velpatasvir Sponsors: Amit D Tevar, MD; University of Pittsburgh Medical Center Not yet recruiting
Condition: Delayed Sleep Phase Interventions: Other: Increase morning bright light; Other: Decrease evening blue light; Behavioral: Sleep scheduling; Behavioral: Monitor sleep, mood, and substance use Sponsors: University of Pittsburgh; National Institute on Drug Abuse (NIDA) Recruiting
Conditions: Nutrition; Diet Modification; Preventive Medicine; Cardiovascular Diseases; Health Promotion Intervention: Other: Diet Assessment Survey Sponsors: Penn State University; American Heart Association Active, not recruiting
Condition: Smoking, Cigarette Interventions: Other: LNC Cigarettes + Colored Packaging; Other: Own Brand Sponsors: Andrew Strasser; Food and Drug Administration (FDA); National Cancer Institute (NCI); University of Pennsylvania Not yet recruiting
Conditions: Liver Diseases; Healthy; Cirrhosis, Liver; Fibrosis Intervention: Device: Group K Diagnostic point of care device Sponsors: University of Pennsylvania; Group K Diagnostics Recruiting
Condition: Cocaine Use Disorder Interventions: Behavioral: Prize-Based Contingency Management; Behavioral: Treatment As Usual Outpatient Substance Use Treatment Sponsor: VA Office of Research and Development Not yet recruiting
Conditions: Schizophrenia; Schizo Affective Disorder Interventions: Drug: Cromoglycate; Drug: Placebo Sponsors: Vishwajit Nimgaonkar, MD PhD; Stanley Medical Research Institute Recruiting
Condition: Acute Lymphoid Leukemia Intervention: Biological: huCART19 Sponsors: University of Pennsylvania; Children's Hospital of Philadelphia Recruiting
Conditions: Hypothermia Following Anesthesia; Hypothermia; Surgery Interventions: Device: EnsoETM; Device: Surface Warming Sponsors: Advanced Cooling Therapy, LLC; Thomas Jefferson University Recruiting
Conditions: Pulmonary Hypertension; Heart Failure With Normal Ejection Fraction; Pulmonary Heart Disease and Diseases of Pulmonary Circulation Interventions: Drug: Nitrates; Drug: Chlorhexidine Gluconate Mouthwash; Drug: Placebo Mouthwash Sponsors: Gladwin, Mark, MD; National Institutes of Health (NIH); National Heart, Lung, and Blood Institute (NHLBI); University of Pittsburgh Not yet recruiting
Conditions: Resilience; Mood; Performance; Stress, Psychological Intervention: Behavioral: 8-Days in an Isolation, Confinement Unit Sponsors: University of Pennsylvania; University of Pittsburgh; National Aeronautics and Space Administration (NASA) Recruiting
Condition: Long QT Syndrome Intervention: Genetic: Simplified Cascade Screening Sponsors: University of Maryland; National Human Genome Research Institute (NHGRI) Recruiting
Condition: Hepatocellular Carcinoma Interventions: Drug: Abemaciclib; Drug: Nivolumab Sponsor: Abramson Cancer Center of the University of Pennsylvania Not yet recruiting
Condition: Obesity Interventions: Behavioral: Behavioral Treatment; Drug: Placebo; Drug: Liraglutide 3.0 mg Sponsors: University of Pennsylvania; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Not yet recruiting
Conditions: Adolescent; Young Adult; Cancer; Physical Activity; Psychological Distress; Social Isolation Interventions: Behavioral: Physical Activity Intervention; Behavioral: Placebo Sponsor: Milton S. Hershey Medical Center Not yet recruiting
Conditions: Insomnia; Insomnia Chronic Intervention: Drug: Zolpidem tartrate Sponsors: University of Pennsylvania; National Institutes of Health (NIH); National Institute on Aging (NIA) Not yet recruiting
Conditions: Down Syndrome; Augmentative and Alternative Communication Interventions: Device: AAC Technology - Standard of Care; Device: AAC Technology - non-optimal integrated arrangement Sponsors: Penn State University; Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Recruiting
Conditions: PE - Pulmonary Embolism; PE - Pulmonary Thromboembolism Intervention: Device: FlowTriever System Sponsor: Inari Medical Enrolling by invitation
Condition: Mesotheliomas Pleural Interventions: Drug: Pembrolizumab; Procedure: Indocyanine Green (ICG) Image-Guided Surgery; Drug: Cisplatin; Drug: Pemetrexed Sponsor: Abramson Cancer Center of the University of Pennsylvania Not yet recruiting
Condition: Cancer of Head and Neck Intervention: Other: Evidenced-based symptom management and coping intervention Sponsor: Fox Chase Cancer Center Recruiting
Conditions: Leukemia, Myeloid, Acute; Leukemia, Lymphoid, Acute; Cardiotoxicity Intervention: Other: observation only Sponsor: Abramson Cancer Center of the University of Pennsylvania Enrolling by invitation
Condition: Medical Education Intervention: Other: Flipped Classroom education Sponsors: Children's Hospital of Philadelphia; American Academy of Pediatrics Section of Neonatal-Perinatal Medicine; Organization of Neonatal-Perinatal Medicine Training Program Directors Active, not recruiting
Condition: Melanoma Interventions: Drug: Pembrolizumab; Procedure: Wide Excision and Sentinel Lymph Node (SLN) Biopsy Sponsor: Abramson Cancer Center of the University of Pennsylvania Recruiting
Conditions: Preeclampsia; Gestational Hypertension; Hypertension; Obesity; Overweight and Obesity; Pregnancy Complications; Pregnancy Toxemia; Postpartum Preeclampsia Interventions: Behavioral: Home Blood Pressure Monitoring; Behavioral: Heart Health 4 New Moms; Other: Usual care Sponsor: University of Pittsburgh Recruiting
Conditions: Communication; Critical Illness Intervention: Behavioral: CICU Team And Loved Ones Communicating (CICU TALC) Sponsor: Children's Hospital of Philadelphia Recruiting
