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    Ellijay, Georgia 30536
    United States

    Post your clinical trial on JoinClinicalTrials.com

    05-09-2019 01:01PM

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  • Nivolumab in Combination With Talazoparib in Melanoma and Mutations in BRCA or BRCA-ness Genes
    NCT04187833
    Condition:   Metastatic or Unresectable Melanoma
    Interventions:   Drug: Nivolumab;   Drug: Talazoparib
    Sponsor:   Pauline Funchain
    Not yet recruiting
  • 5-Azacitidine and Decitabine Epigenetic Therapy for Myeloid Malignancies
    NCT04187703
    Conditions:   Myelodysplastic Syndromes;   MDS/MPN Crossover Syndromes
    Interventions:   Drug: 5-azacytidine;   Drug: Decitabine
    Sponsor:   Case Comprehensive Cancer Center
    Not yet recruiting
  • Personalized Treatment Algorithms for Difficult-to-treat Asthma
    NCT04179461
    Condition:   Asthma in Children
    Interventions:   Drug: Cholecalciferol;   Drug: antihistamine;   Drug: Azithromycin;   Drug: emollient cream;   Drug: Fluticasone Propionate;   Drug: Asthma Controller Medication
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Completed
  • A 48-Week, Open Label, Study to Evaluate the Efficacy and Safety of Casimersen, Eteplirsen and Golodirsen in Subjects With Duchenne Muscular Dystrophy Carrying Eligible DMD Duplications
    NCT04179409
    Condition:   Duchenne Muscular Dystrophy
    Interventions:   Drug: Casimersen;   Drug: Eteplirsen;   Drug: Golodirsen
    Sponsors:   Kevin Flanigan;   Sarepta Therapeutics, Inc.
    Not yet recruiting
  • Phase I Norovirus Challenge Model
    NCT04174560
    Condition:   Gastroenteritis Norovirus
    Intervention:   Biological: Norovirus GII.4 Challenge Pool
    Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
    Not yet recruiting
  • Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)
    NCT04174157
    Condition:   Spinal Muscular Atrophy (SMA)
    Intervention:   Other: Prospective observational registry
    Sponsors:   AveXis, Inc.;   United BioSource Corporation
    Recruiting
  • Tools to Improve Medication Continuity in Adolescents With ADHD
    NCT04173000
    Condition:   Attention Deficit Hyperactivity Disorder
    Interventions:   Other: Mehealth for ADHD software with medication continuity tools;   Other: Mehealth for ADHD software with no medication continuity tools
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Recruiting
  • GDNF Gene Therapy for Parkinson's Disease
    NCT04167540
    Condition:   Parkinson's Disease
    Intervention:   Biological: AAV2-GDNF
    Sponsor:   Brain Neurotherapy Bio, Inc.
    Not yet recruiting
  • Dasatinib in Preventing Oxaliplatin-Induced Peripheral Neuropathy in Patients With Colorectal Cancer Receiving FOLFOX and Bevacizumab
    NCT04164069
    Conditions:   Advanced Colorectal Carcinoma;   Metastatic Colorectal Carcinoma;   Stage IV Colorectal Cancer AJCC v8;   Stage IVA Colorectal Cancer AJCC v8;   Stage IVB Colorectal Cancer AJCC v8;   Stage IVC Colorectal Cancer AJCC v8
    Interventions:   Biological: Bevacizumab;   Drug: Dasatinib;   Drug: Fluorouracil;   Drug: Leucovorin;   Drug: Leucovorin Calcium;   Drug: Oxaliplatin;   Other: Quality-of-Life Assessment
    Sponsors:   Anne Noonan;   National Cancer Institute (NCI)
    Not yet recruiting
  • Contingency Management Using Smartphone App in Patients With SUD
    NCT04162132
    Condition:   Substance Use Disorders
    Intervention:   Device: Smartphone app
    Sponsors:   BrightView LLC;   DynamiCare Health
    Completed
  • An Open Label Study to Evaluate the Impact of Duration of Subcutaneous Infusion of a Novel, pH Neutral Formulation of Furosemide (Furoscix®) on Safety and Local Skin Tolerability
    NCT04161482
    Condition:   Healthy
    Intervention:   Drug: Furosemide 80 mg (8 mg/mL)
    Sponsors:   scPharmaceuticals, Inc.;   Clinical Trial Data Services, Inc.;   CSSi Life Sciences
    Not yet recruiting
  • Study of Autologous Peripheral Blood Lymphocytes in the Treatment of Patients With CLL or SLL
    NCT04155710
    Conditions:   Chronic Lymphocytic Leukemia;   Small Lymphocytic Lymphoma
    Interventions:   Biological: IOV-2001;   Drug: Low dose IL-2;   Drug: High dose IL-2;   Drug: IL-2
    Sponsor:   Iovance Biotherapeutics, Inc.
    Recruiting
  • Arts & Health Education to Improve Health, Resilience, and Well-Being
    NCT04154579
    Conditions:   Hypertension;   Diabetes;   Obesity;   COPD;   CHF;   High Cholesterol;   Asthma;   Chronic Pain;   Multiple Sclerosis;   Depression;   Anxiety;   Heart Diseases;   Stroke
    Interventions:   Behavioral: HeRe We Arts;   Behavioral: HeRe We Ed
    Sponsors:   The Cleveland Clinic;   National Endowment for the Arts;   Cuyahoga Arts and Culture
    Recruiting
  • Spiritual Flow and Nurse Wellbeing
    NCT04153656
    Condition:   Burnout, Professional
    Intervention:   Other: Reading and studying Spiritual Flow
    Sponsors:   Mercy Health Ohio;   St. Elizabeth Youngstown Hospital
    Recruiting
  • Cooking Matters for Diabetes - A 6-Week Program for Practical Application of Diabetes Self-Management Education
    NCT04152811
    Conditions:   Diabetes Mellitus;   Type 1 Diabetes;   Type 2 Diabetes
    Interventions:   Behavioral: Cooking Matters for Diabetes;   Other: Usual Diabetes Care
    Sponsors:   Ohio State University;   Academy of Nutrition and Dietetics
    Recruiting
  • Randomized Controlled Trial Comparing eTEP and Laparoscopic Intraperitoneal Onlay Mesh (IPOM) for Ventral Hernias
    NCT04150796
    Conditions:   Ventral Hernia;   Umbilical Hernia;   Epigastric Hernia
    Intervention:   Procedure: Ventral Hernia Repair
    Sponsor:   The Cleveland Clinic
    Recruiting
  • Aspirin Effects on Emotional Reactions
    NCT04146532
    Condition:   Healthy Adults
    Interventions:   Drug: Aspirin 500 MG;   Drug: Placebo
    Sponsor:   Ohio State University
    Recruiting
  • Quantitative Magnetic Resonance Imaging (MRI) Sub-Study of MS PATHS
    NCT04145284
    Condition:   Multiple Sclerosis
    Intervention:  
    Sponsor:   Biogen
    Enrolling by invitation
  • Clinical Validation of Omron WheezeScan
    NCT04144699
    Conditions:   Asthma in Children;   Bronchitis;   Bronchiolitis
    Intervention:  
    Sponsors:   Omron Healthcare Co., Ltd.;   University of Wisconsin, Madison;   Children's Hospital Medical Center, Cincinnati;   Le Bonheur Children's Hospital;   University of Chicago
    Recruiting
  • Patient-Centered PD Ambulatory Monitoring System
    NCT04142528
    Condition:   Parkinson Disease
    Intervention:   Device: ParkinPal
    Sponsors:   Great Lakes NeuroTechnologies Inc.;   National Institute of Nursing Research (NINR)
    Enrolling by invitation
  • Digital PET Scan for the Prediction of Outcomes in Patients With Locally Advanced Oropharyngeal Cancer
    NCT04140513
    Conditions:   Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8;   Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8;   Locally Advanced Oropharyngeal Squamous Cell Carcinoma;   Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8;   Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8;   Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8;   Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8;   Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8
    Interventions:   Radiation: Fludeoxyglucose F-18;   Procedure: Positron Emission Tomography
    Sponsors:   Ohio State University Comprehensive Cancer Center;   National Cancer Institute (NCI)
    Not yet recruiting
  • Vitamin D Supplementation as a Neoadjuvant for Photodynamic Therapy of Actinic Keratoses
    NCT04140292
    Condition:   Actinic Keratosis
    Interventions:   Drug: Photodynamic therapy (PDT);   Drug: Vitamin D3
    Sponsor:   Case Comprehensive Cancer Center
    Not yet recruiting
  • Standing Balance as the Fifth Vital Sign in Clinical Setting
    NCT04139642
    Conditions:   Accidental Fall;   Postural Balance;   Clinical Decision-making
    Intervention:   Device: SimpleSway
    Sponsors:   Ohio State University;   Bertec Corporation;   National Institute on Aging (NIA)
    Recruiting
  • Motor Unit Number Estimation (MUNE) in Adults With Spinal Muscular Atrophy (SMA)
    NCT04139343
    Condition:   Spinal Muscular Atrophy
    Intervention:  
    Sponsor:   Ohio State University
    Recruiting
  • Young Adult Congenital Heart Disease Physical Activity Lifestyle Study (YACHD-PALS)
    NCT04135859
    Conditions:   Cardiovascular Disease Other;   Physical Activity
    Interventions:   Behavioral: Physical Activity Lifestyle Intervention;   Behavioral: Physical Activity Monitoring
    Sponsor:   Jamie Jackson
    Enrolling by invitation
  • Prevention of OUD: The HOME Project (Housing, Opportunities, Motivation and Engagement)
    NCT04135703
    Condition:   Substance Use
    Intervention:   Behavioral: SBOA + Housing
    Sponsors:   Ohio State University;   Nationwide Children's Hospital
    Not yet recruiting
  • A Study to Assess the Efficacy, Safety and Tolerability of Oral LPCN 1144 in Subjects With Nonalcoholic Steatohepatitis (NASH)
    NCT04134091
    Condition:   Nonalcoholic Steatohepatitis (NASH)
    Interventions:   Drug: LPCN 1144 Formulation A;   Drug: LPCN 1144 Formulation B;   Drug: Placebo
    Sponsor:   Lipocine Inc.
    Recruiting
  • Comparative Imaging Assessment of Valvular Heart Disease
    NCT04126018
    Conditions:   Valve Heart Disease;   Aortic Stenosis;   Aortic Regurgitation
    Interventions:   Diagnostic Test: MRI with strain measurement;   Diagnostic Test: Echocardiography
    Sponsor:   The Cleveland Clinic
    Recruiting
  • Safety and Efficacy of the Noxsano Wound Care Bandage
    NCT04123093
    Conditions:   Wound Heal;   Peripheral Artery Disease;   Ulcer, Leg;   Ulcer Foot;   Diabetic Foot Ulcer;   Arterial Insufficiency
    Interventions:   Device: Noxsano Bandage (Healthy Volunteers);   Device: Noxsano Bandage (Wound Care)
    Sponsors:   OhioHealth;   Noxsano, Inc.
    Recruiting
  • DNA Repair Activity in the Skin of Day and Night Shift Workers
    NCT04122456
    Condition:   Skin Cancer
    Interventions:   Radiation: Ultraviolet B Radiation;   Other: No Ultraviolet B Radiation
    Sponsor:   Jeffrey B. Travers, MD, PhD
    Not yet recruiting
  • Objective Quality of Life Detection Validation
    NCT04121793
    Condition:   Parkinson Disease
    Intervention:   Device: Kinesia 360 and Smartphone sensors
    Sponsors:   Great Lakes NeuroTechnologies Inc.;   National Institute on Minority Health and Health Disparities (NIMHD)
    Recruiting
  • Ramucirumab and Pembrolizumab for the Treatment of EGFR Mutant Recurrent or Metastatic Non-small Cell Lung Cancer
    NCT04120454
    Conditions:   Metastatic Lung Non-Small Cell Carcinoma;   Recurrent Lung Non-Small Cell Carcinoma;   Stage IV Lung Cancer AJCC v8;   Stage IVA Lung Cancer AJCC v8;   Stage IVB Lung Cancer AJCC v8
    Interventions:   Biological: Pembrolizumab;   Biological: Ramucirumab
    Sponsors:   Ohio State University Comprehensive Cancer Center;   National Cancer Institute (NCI)
    Not yet recruiting
  • A Pilot Study of Collaborative Assessment and Management of Suicidality With Suicidal Children ("CAMS-4Kids")
    NCT04119648
    Conditions:   Suicidal Ideation;   Suicide, Attempted
    Intervention:   Behavioral: CAMS-4Kids
    Sponsors:   Nationwide Children's Hospital;   The Catholic University of America
    Not yet recruiting
  • Xylitol - Healthcare Associated Infection Reduction in Stem Cell Transplant Patients
    NCT04117477
    Condition:   Allogeneic Hematopoietic Cell Transplantation
    Interventions:   Drug: Xylitol;   Other: Placebo
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Recruiting
  • Endobronchial Ultrasound-Guided Transbronchial Needle-Aspiration With Suction in Obtaining Samples From Patients With Suspected Nodal Metastatic Lung Cancer
    NCT04116970
    Condition:   Lung Carcinoma
    Interventions:   Procedure: Bronchoscopy;   Procedure: Ultrasound-Guided Transbronchial Needle Aspiration
    Sponsors:   Ohio State University Comprehensive Cancer Center;   National Cancer Institute (NCI)
    Not yet recruiting
  • Digital Home Blood Pressure Monitoring in Type B Aortic Dissection Patients
    NCT04116684
    Conditions:   Aortic Dissection;   Hypertension
    Intervention:   Device: Withings Digital Blood Pressure Monitor
    Sponsor:   The Cleveland Clinic
    Recruiting
  • Stimulation Combined With Powered Motorized Orthoses for Walking After Stroke
    NCT04116671
    Conditions:   Stroke;   Hemiparesis
    Intervention:   Device: Neuromechanical Gait Assist
    Sponsor:   VA Office of Research and Development
    Not yet recruiting
  • Biologically Optimized Infusion Schedule of Gemcitabine and Nab-Paclitaxel for the Treatment of Metastatic Pancreatic Cancer
    NCT04115163
    Conditions:   Metastatic Pancreatic Adenocarcinoma;   Stage IV Pancreatic Cancer AJCC v8
    Interventions:   Drug: Gemcitabine;   Drug: Nab-paclitaxel
    Sponsors:   Laith Abushahin;   National Cancer Institute (NCI)
    Not yet recruiting
  • An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 Combined With Low-Dose Cytarabine (LDAC) or Decitabine in Patients With Acute Myeloid Leukemia (AML)
    NCT04113616
    Conditions:   Acute Myeloid Leukemia (AML);   Acute Myeloid Leukemia (AML), Secondary to Myeloproliferative Neoplasms (MPN)
    Interventions:   Drug: KRT-232;   Drug: Cytarabine;   Drug: Decitabine
    Sponsor:   Kartos Therapeutics, Inc.
    Recruiting
  • Individualized Exercise Oncology Program for Newly Diagnosed Breast Cancer Patients
    NCT04106609
    Condition:   Breast Cancer
    Interventions:   Other: Supervised, individualized exercise oncology program;   Other: Current standard of care
    Sponsor:   Karen Wonders
    Recruiting
  • Validation of a Quality of Life Metric "Prolac-10"
    NCT04106531
    Conditions:   Prolactinoma;   Prolactin-Producing Pituitary Tumor;   Pituitary Tumor;   Prolactinoma Macroadenoma;   Prolactinoma Microadenoma
    Intervention:  
    Sponsor:   Ohio State University
    Not yet recruiting
  • Self-Management in Parents of Technology-Dependent Children
    NCT04105244
    Conditions:   Caregivers;   Parents;   Self-Management;   Chronic Illnesses, Multiple
    Intervention:   Behavioral: Resourcefulness Training©
    Sponsor:   University Hospitals Cleveland Medical Center
    Recruiting
  • The Natural History of Parkinson's Disease-associated Spinal Disorders
    NCT04101513
    Conditions:   Parkinson Disease;   Idiopathic Parkinson Disease
    Intervention:  
    Sponsor:   Ohio State University
    Recruiting
  • Neural Correlates of Knee Sensorimotor Control in Patients With Patelleofemoral Pain Syndrome
    NCT04099004
    Conditions:   Patellofemoral Pain Syndrome;   Patello Femoral Syndrome;   Patellofemoral Syndrome
    Intervention:  
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Recruiting
  • TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients
    NCT04098445
    Conditions:   Hematopoietic Stem Cell Transplant (HSCT);   Diffuse Alveolar Hemorrhage;   Thrombotic Microangiopathies;   Interstitial Pneumonitis;   Bronchiolitis Obliterans
    Intervention:  
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Not yet recruiting
  • Synbiotic Dietary Supplement and Gut Microbiota
    NCT04097106
    Condition:   Healthy
    Intervention:   Dietary Supplement: Synbiotic
    Sponsor:   The Cleveland Clinic
    Not yet recruiting
  • Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic Encephalopathy
    NCT04096014
    Condition:   Hepatic Encephalopathy
    Interventions:   Dietary Supplement: Ensure Enlive;   Other: Standard Of Care
    Sponsor:   The Cleveland Clinic
    Recruiting
  • Sirolimus for Cowden Syndrome With Colon Polyposis
    NCT04094675
    Conditions:   PTEN Gene Mutation;   PTEN Hamartoma Tumor Syndrome;   PTEN Hamartoma Syndrome;   Cowden Syndrome;   Bannayan Syndrome;   Bannayan Zonana Syndrome;   Polyposis
    Intervention:   Drug: Sirolimus
    Sponsors:   Ohio State University;   PTEN Research
    Recruiting
  • Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation
    NCT04093986
    Conditions:   Sickle Cell Disease;   Sickle Cell Anemia
    Interventions:   Other: Chart Review;   Other: Survey
    Sponsors:   Children's Hospital Medical Center, Cincinnati;   University of Connecticut;   University of Colorado, Denver;   Guy's and St Thomas' NHS Foundation Trust;   Duke University;   Children's Hospital of Philadelphia
    Recruiting
  • Boiled Peanut Oral Immunotherapy
    NCT04090203
    Condition:   Peanut Hypersensitivity
    Intervention:   Drug: Boiled Peanut Powder
    Sponsors:   Alton Melton;   The Cleveland Clinic
    Enrolling by invitation
  • Online Acceptance and Commitment Therapy for Chronic Pain in Sample of People With Chiari Malformation
    NCT04089670
    Conditions:   Chronic Pain;   Chiari Malformation
    Intervention:   Behavioral: Online Acceptance and Commitment Therapy Intervention
    Sponsors:   Kent State University;   Utah State University;   Conquer Chiari
    Recruiting
  • LDL-Apheresis for FSGS CardioRenal Outcomes
    NCT04088799
    Condition:   Focal Segmental Glomerulosclerosis
    Intervention:   Other: No intervention
    Sponsors:   Children's Hospital Medical Center, Cincinnati;   Kaneka Pharma America LLC
    Enrolling by invitation
  • TCRαβ+/CD19+ Depleted Allogeneic Hematopoietic Stem Cell Transplantation for Malignant and Non-malignant Disorders
    NCT04088760
    Condition:   Allogeneic Hematopoietic Cell Transplantation
    Intervention:   Drug: TCRαβ+/CD19+ depleted allogeneic hematopoietic stem cell transplant (HSCT)
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Recruiting
  • Peripheral Blood Mononuclear Cells Response In Healthy Controls, Heavy Drinkers, and Patients With Alcoholic Hepatitis
    NCT04088370
    Condition:   Alcoholic Hepatitis
    Intervention:   Other: Blood Draw
    Sponsor:   The Cleveland Clinic
    Recruiting
  • Long-Term Longitudinal QoL in Patients Undergoing EEA
    NCT04087902
    Conditions:   Pituitary Tumor;   Meningioma;   Rathke Cleft Cysts;   Chordoma;   Chondrosarcoma;   Craniopharyngioma;   Encephalocele;   Esthesioneuroblastoma
    Intervention:  
    Sponsor:   Ohio State University
    Recruiting
  • Southeast Asian Women's Health Project
    NCT04086771
    Conditions:   Breast Cancer;   Cervical Cancer
    Interventions:   Behavioral: Navigation;   Other: Information only
    Sponsors:   Ohio State University;   University of South Florida;   American Cancer Society, Inc.
    Not yet recruiting
  • Teaching Caregivers of Hospice Patients to Administer Reiki
    NCT04086017
    Conditions:   Hospice;   Pain;   Anxiety;   Stress
    Intervention:   Other: Reiki therapy
    Sponsors:   Ohio State University;   OhioHealth
    Not yet recruiting
  • Using Augmentative & Alternative Communication to Promote Language Recovery for People With Post-Stroke Aphasia
    NCT04081207
    Conditions:   Post-stroke Aphasia;   Aphasia
    Intervention:   Behavioral: AAC for Language Recovery (AAC-LaRc)
    Sponsors:   University of Cincinnati;   Children's Hospital Medical Center, Cincinnati
    Recruiting
  • Inherited and Non-inherited Cardiac Disease Quality of Life
    NCT04080492
    Conditions:   Hypertrophic Obstructive Cardiomyopathy;   Thoracic Aortic Aneurysm;   Heart Disease Caused by Ionising Radiation;   Quality of Life
    Intervention:   Other: QOL Survey
    Sponsor:   The Cleveland Clinic
    Recruiting
  • Glycemic Control Based on Serum Fructosamine Concentration vs. hemoglobinA1c (HbA1c) in Diabetic Patients
    NCT04079660
    Condition:   Diabetes
    Intervention:   Diagnostic Test: Capillary blood glucose blood draw
    Sponsor:   Ohio State University
    Active, not recruiting
  • High Definition Neuromuscular Stimulation in Tetraplegia
    NCT04075812
    Condition:   Spinal Cord Injury at C4-C6 Level
    Intervention:   Device: Neuromuscular Stimulator
    Sponsor:   Ohio State University
    Completed
  • Community Benefit of No-charge Calcium Score Screening Program
    NCT04075162
    Condition:   Cardiovascular Risk Factor
    Intervention:  
    Sponsor:   University Hospitals Cleveland Medical Center
    Recruiting
  • A Study of TAK-981 in Combination With Rituximab in Participants With Relapsed/Refractory (r/r) CD20-positive (CD20+) Non-Hodgkin Lymphoma (NHL)
    NCT04074330
    Condition:   Lymphoma, Non-hodgkin
    Interventions:   Drug: TAK-981;   Drug: Rituximab
    Sponsor:   Millennium Pharmaceuticals, Inc.
    Recruiting
  • Mesenchymal Stem Cells for the Treatment of Pouch Fistulas in Crohn's
    NCT04073472
    Conditions:   Crohn's Disease;   Fistula;   Anal Fistula;   Pouch, Ileal;   Pouches, Ileoanal
    Intervention:   Drug: mesenchymal stem cells (MSCs)
    Sponsor:   The Cleveland Clinic
    Not yet recruiting
  • Neuroplastic Mechanisms Underlying Augmented Neuromuscular Training
    NCT04069520
    Condition:   Anterior Cruciate Ligament Injuries
    Interventions:   Other: Augmented biofeedback;   Other: Sham comparator
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Recruiting
  • Comparison of Lithotripsy Urolithiasis Machines
    NCT04069338
    Conditions:   Kidney Stone;   Kidney Calculi;   Ureteral Calculi;   Ureterolithiasis;   Urolithiasis
    Intervention:   Procedure: Lithotripter
    Sponsor:   The Cleveland Clinic
    Recruiting
  • Standard vs Mini-PCNL for the Treatment of Stone Disease
    NCT04069013
    Conditions:   Urolithiasis;   Kidney Stone;   Kidney Calculi;   Ureteral Calculi;   Kidney Diseases
    Intervention:   Procedure: PCNL
    Sponsors:   The Cleveland Clinic;   University of British Columbia;   Massachusetts General Hospital;   Vanderbilt University Medical Center;   Duke University;   Ohio State University;   Columbia University;   Dartmouth-Hitchcock Medical Center
    Not yet recruiting
  • Implementation of Multidisciplinary Assessments for Geriatric Patients in an ED Observation Unit
    NCT04068311
    Conditions:   Fall Patients;   Delirium;   Quality of Life;   Functional Status
    Intervention:   Other: Geriatric Screening tools
    Sponsors:   Ohio State University;   National Institute on Aging (NIA)
    Recruiting
  • Growth and Tolerance Trial on Infant Formula With HMO
    NCT04066413
    Condition:   Healthy Growth
    Interventions:   Other: Standard infant formula;   Other: Infant formula supplemented with HMO
    Sponsor:   FrieslandCampina
    Recruiting
  • Feasibility Study for Intrathoracic Nerve Stimulation
    NCT04066374
    Condition:   Postoperative Pain
    Intervention:   Device: Peripheral Nerve Stimulation
    Sponsor:   The Cleveland Clinic
    Recruiting
  • A Dietary Intervention Study on the Microbiome in Crohn's Disease Patients
    NCT04065048
    Condition:   Crohn Disease
    Intervention:   Other: Soy based diet
    Sponsors:   Case Western Reserve University;   University of California, Davis;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   University Hospitals Cleveland Medical Center
    Not yet recruiting
  • Virtual Visits to Optimize Research Trial Offerings to HF Patients
    NCT04064541
    Conditions:   Heart Failure, Systolic;   Heart Failure With Preserved Ejection Fraction
    Intervention:   Other: Virtual Visit
    Sponsor:   The Cleveland Clinic
    Recruiting
  • Evaluation of Perforator Phase Contrast Angiography in Developing Surgery Plans for Patients With Breast Cancer Undergoing Breast Reconstruction With Free-Flap Methods After Mastectomy
    NCT04063410
    Condition:   Mammoplasty Patient
    Interventions:   Procedure: Angiography;   Procedure: MRI-Based Angiogram;   Other: Quality-of-Life Assessment
    Sponsors:   Ohio State University Comprehensive Cancer Center;   National Cancer Institute (NCI)
    Not yet recruiting
  • Persistent Postpartum Cardiovascular Dysfunction in Patients With Preeclampsia
    NCT04063397
    Conditions:   Preeclampsia;   Preeclampsia Severe;   Cardiac Complication
    Interventions:   Diagnostic Test: Echocardiogram;   Diagnostic Test: Blood draw
    Sponsors:   Ohio State University;   Roche Diagnostics
    Recruiting
  • SAGE for the Early Detection of Cognitive Impairment at Primary Care Provider Visits
    NCT04063371
    Condition:   Cognitive Impairment
    Interventions:   Other: Self-Administered Gerocognitive Examination (SAGE) or Electronic Self-Administered Gerocognitive Examination (eSAGE);   Other: Informant Conversation
    Sponsor:   Ohio State University
    Not yet recruiting
  • Minimal Occlusive Pressure With Cuffed ETTs: The Effect of 3 Different Sizes of cETT on Intracuff Pressure in Children
    NCT04061629
    Condition:   Surgical Procedure, Unspecified
    Intervention:   Device: Cuffed ETT
    Sponsor:   Nationwide Children's Hospital
    Enrolling by invitation
  • A Study to Evaluate the Long Term Safety of OTX-TP (Sustained Release Travoprost) Intracanalicular Insert
    NCT04061044
    Condition:   Open Angle Glaucoma and Ocular Hypertension
    Intervention:   Drug: Ophthalmic Insert
    Sponsor:   Ocular Therapeutix, Inc.
    Active, not recruiting
  • Fecal Microbiota Transplantation For The Treatment Of Gastro-Intestinal Acute GVHD
    NCT04059757
    Condition:   Gastro-Intestinal Acute Graft Versus Host Disease (GI-aGVHD)
    Intervention:   Biological: Fecal Microbiota Transplantation (FMT)
    Sponsor:   Leland Metheny
    Not yet recruiting
  • Building Family Caregiver Skills Using a Simulation-Based Intervention for Care of Cancer Patients
    NCT04055948
    Condition:   Cancer
    Interventions:   Behavioral: One-on-one teaching sessions;   Behavioral: Telephone booster contact
    Sponsor:   Case Comprehensive Cancer Center
    Not yet recruiting
  • The Effect of the Low Fodmap Diet in Children With Autism Spectrum Disorders
    NCT04054349
    Condition:   Autism Spectrum Disorder
    Intervention:   Other: Low FODMAP diet
    Sponsor:   Ohio State University
    Completed
  • Regorafenib in Bevacizumab Refractory Recurrent Glioblastoma
    NCT04051606
    Condition:   Recurrent Glioblastoma
    Intervention:   Drug: Regorafenib
    Sponsor:   Case Comprehensive Cancer Center
    Recruiting
  • Effect of a Vibratory Stimulus on Mitigating Nociception-specific Responses to Skin Puncture in Neonates
    NCT04050384
    Conditions:   Infant, Newborn;   Infant, Premature;   Pain Perception;   Pain Measurement;   Pain Management;   Electroencephalography
    Intervention:   Device: Baby GentleStick
    Sponsor:   Lance Relland
    Recruiting
  • Vyxeos for Re-induction Treatment of Acute Myeloid Leukemia Patients With Persistent Disease After Induction
    NCT04049539
    Conditions:   Blasts More Than 5 Percent of Bone Marrow Nucleated Cells;   Persistent Disease;   Refractory Acute Myeloid Leukemia
    Intervention:   Drug: Liposome-encapsulated Daunorubicin-Cytarabine
    Sponsors:   Ohio State University Comprehensive Cancer Center;   National Cancer Institute (NCI)
    Not yet recruiting
  • Clinical and Radiological Outcomes of Posterior Cervical Fusion Supplemented With Interfacet Spacers
    NCT04041583
    Condition:   Cervical Fusion
    Intervention:   Device: Cervical Interfacet Spacers
    Sponsors:   Ohio State University;   Medtronic
    Recruiting
  • Healthy Eating, Activity and Reduction of Teen Stress
    NCT04038684
    Conditions:   Overweight and Obesity;   Overweight Adolescents;   Emotional Stress;   Stress, Psychological;   Eating Behavior
    Interventions:   Behavioral: Mindfulness-Based Weight Control (MBWC);   Behavioral: Standard Behavioral Weight Control (SBWC)
    Sponsors:   Kent State University;   Case Western Reserve University;   The Miriam Hospital;   Brown University;   Rhode Island Hospital;   University of North Carolina, Chapel Hill
    Recruiting
  • Triamcinolone With Vitamin D Synergistic Efficacy in Psoriasis
    NCT04036188
    Conditions:   Plaque Psoriasis;   Vitamin D3
    Interventions:   Drug: Triamcinolone;   Dietary Supplement: Vitamin D3;   Drug: Placebo
    Sponsor:   Wright State Physicians
    Not yet recruiting
  • Comprehensive Study of Post-surgical Pain After Pectus or Spine Surgery
    NCT04031716
    Conditions:   Pain, Postoperative;   Excavatum, Pectus;   Scoliosis Idiopathic
    Intervention:   Behavioral: Meditation
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Enrolling by invitation
  • Randomized Trial of LENA Home in A Home Visiting Program
    NCT04031326
    Conditions:   Parent-Child Relations;   Language Development
    Intervention:   Behavioral: LENA Home
    Sponsors:   Children's Hospital Medical Center, Cincinnati;   Every Child Succeeds;   The Carol Ann and Ralph V. Haile, Jr./U.S. Bank Foundation;   Bethesda, Inc.
    Recruiting
  • Comparing Children's Books to Brochures for Safe Sleep and Infant Reading Education During Prenatal Care
    NCT04031235
    Conditions:   Sudden Unexplained Infant Death;   Child Rearing;   Literacy
    Interventions:   Behavioral: Sleep Baby, Safe and Snug;   Behavioral: Read Baby, Every Day
    Sponsors:   Children's Hospital Medical Center, Cincinnati;   The DeCavel Family SIDS Foundation
    Recruiting
  • Corneal Oxygen Uptake With Apioc Contact Lenses
    NCT04031118
    Condition:   Contact Lens-Induced Corneal Disorder of Both Eyes (Diagnosis)
    Intervention:   Device: Apioc Contact Lens
    Sponsor:   Lentechs, LLC
    Enrolling by invitation
  • Improving Print Knowledge for Children With Hearing Loss
    NCT04027881
    Condition:   Hearing Loss
    Intervention:   Behavioral: Sit Together and REad
    Sponsor:   Ohio State University
    Not yet recruiting
  • Targeted Breast Milk Fortification for Very Low Birth Weight Infants in the NICU
    NCT04025021
    Conditions:   Human Milk;   Neonate;   Breast Milk
    Interventions:   Dietary Supplement: Targeted Fortification;   Device: The Miris Human Milk Analyzer
    Sponsor:   MetroHealth Medical Center
    Enrolling by invitation
  • Sequential Hypo- and Normo-thermic Perfusion to Preserve Extended Criteria Donor Livers for Transplantation
    NCT04023773
    Condition:   Liver Transplantation
    Intervention:   Device: Liver Machine Perfusion (MP) device
    Sponsor:   The Cleveland Clinic
    Not yet recruiting
  • Myeloid-Derived Suppressor Cell Function in Breast Cancer Patients
    NCT04022616
    Condition:   Breast Cancer
    Intervention:   Other: Specimen collection
    Sponsors:   Ohio State University Comprehensive Cancer Center;   National Cancer Institute (NCI)
    Recruiting
  • The Effects of Oscillating-Rotating Electric Toothbrushes on Plaque and Gingival Health
    NCT04017507
    Conditions:   Gingivitis;   Plaque
    Interventions:   Device: Oscillating-rotating electric toothbrush;   Device: Side-to-side electric toothbrush;   Device: Manual toothbrush
    Sponsor:   Procter and Gamble
    Completed
  • Human-Animal Interaction to Promote Recovery Following Pediatric Brain Injury
    NCT04016961
    Conditions:   Brain Injuries;   Acquired Brain Injury;   Traumatic Brain Injury
    Interventions:   Other: AAT - Dog;   Other: TAU - No Dog
    Sponsors:   Children's Hospital Medical Center, Cincinnati;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Not yet recruiting
  • Feasibility of Action Observation and Repetitive Task Practice on Upper Extremity Outcomes in Chronic Stroke Survivors
    NCT04015271
    Conditions:   Stroke;   Hemiparesis
    Interventions:   Behavioral: Action Observation + Repetitive Task Practice;   Behavioral: Placebo Video + Repetitive Task Practice
    Sponsor:   Ohio State University
    Recruiting
  • Study of Pembrolizumab Plus SurVaxM for Glioblastoma at First Recurrence
    NCT04013672
    Condition:   Recurrent Glioblastoma
    Interventions:   Drug: Pembrolizumab;   Drug: SurVaxM;   Drug: Sargramostim;   Drug: Montanide ISA 51
    Sponsor:   Manmeet Ahluwalia, MD
    Not yet recruiting
  • Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC
    NCT04010357
    Condition:   Small-cell Lung Cancer
    Intervention:   Drug: Abemaciclib,
    Sponsor:   Case Comprehensive Cancer Center
    Not yet recruiting
  • Anterior Gastropexy vs. No Anterior Gastropexy for Paraesophageal Hernia Repair
    NCT04007952
    Conditions:   Paraesophageal Hernia;   Hiatal Hernia Large
    Intervention:   Procedure: Anterior Gastropexy
    Sponsor:   The Cleveland Clinic
    Recruiting
  • Single-Armed Use of ViviGen Cellular Bone Matrix in Patients Undergoing Posterolateral Lumbar Surgery
    NCT04007094
    Conditions:   Degenerative Disc Disease;   Spinal Stenosis;   Spondylosis;   Spondylolisthesis
    Intervention:   Drug: ViviGen Cellular Bone Matrix
    Sponsors:   Ohio State University;   DePuy Synthes
    Recruiting
  • Meta-analysis of Stannous Fluoride and the Effects on Dental Plaque
    NCT04006483
    Condition:   Dental Plaque
    Interventions:   Drug: Stannous fluoride dentifrice;   Drug: Positive control dentifrice;   Drug: Negative control dentifrice
    Sponsor:   Procter and Gamble
    Completed
  • Meta-analysis of Stannous Fluoride and the Effects on Enamel Erosion
    NCT04006470
    Condition:   Enamel Erosion
    Interventions:   Drug: Stannous fluoride dentifrice;   Drug: Positive control dentifrice;   Drug: Negative control dentifrice
    Sponsor:   Procter and Gamble
    Completed
  • Meta-analysis of Stannous Fluoride Dentifrice and the Effects on Dentine Hypersensitivity
    NCT04005417
    Condition:   Dentine Hypersensitivity
    Interventions:   Drug: Stannous fluoride dentifrice;   Drug: Positive control dentifrice;   Drug: Negative control dentifrice
    Sponsor:   Procter and Gamble
    Completed
  • Tracking Device Guided Feedback to Enhance Patient Physician Interaction
    NCT04004806
    Conditions:   Physician Patient Relation;   Burnout, Professional
    Intervention:   Device: Hill Rom tracking device
    Sponsors:   The Cleveland Clinic;   Accreditation Council for Graduate Medical Education
    Enrolling by invitation
  • Feasibility of Collecting Stress Biomarkers Among Youth Experiencing Homelessness
    NCT04004520
    Condition:   Stress, Physiological
    Interventions:   Behavioral: Virtual Reality with Meditation;   Behavioral: Audio Control;   Behavioral: Virtual reality Control
    Sponsor:   Ohio State University
    Recruiting
  • Laser Cell Therapy for Knee Cartilage Repair
    NCT04001361
    Condition:   Knee Osteoarthritis
    Intervention:   Procedure: Laser Cell Therapy
    Sponsor:   Endocellutions
    Not yet recruiting
  • Pilot Study of Powered Exoskeleton Use for Gait Rehabilitation in Individuals With Multiple Sclerosis
    NCT04000373
    Conditions:   Multiple Sclerosis;   Gait Disorders, Neurologic
    Intervention:   Device: Ekso GT™ exoskeleton
    Sponsor:   The Cleveland Clinic
    Not yet recruiting
  • Pragmatic Cyclical Lower Extremity Exercise Trial for Parkinson's Disease
    NCT04000360
    Condition:   Parkinson Disease
    Intervention:   Other: High-Intensity Aerobic Exercise
    Sponsors:   The Cleveland Clinic;   National Institutes of Health (NIH)
    Recruiting
  • S-Nitrosylation (SNO) Therapy During Autologous Blood Transfusion
    NCT03999229
    Condition:   Transfusion Related Complication
    Interventions:   Drug: SNO;   Drug: Normal Saline;   Drug: Red Blood Cell
    Sponsors:   James Reynolds;   Case Western Reserve University;   National Heart, Lung, and Blood Institute (NHLBI)
    Recruiting
  • The Effect of Local Analgesia on Postoperative Gluteal Pain in Patients Undergoing Sacrospinous Ligament Fixation: A Randomized Trial
    NCT03995641
    Conditions:   Postoperative Pain;   Pelvic Organ Prolapse;   Trigger Point Injection;   Sacrospinous Ligament Fixation
    Intervention:   Drug: marcaine and kenalog
    Sponsor:   Kettering Health Network
    Recruiting
  • ICE T for Post GYN Surgery Pain
    NCT03987022
    Condition:   Opioid Substitution Treatment
    Interventions:   Drug: Ketorolac;   Drug: Opioids;   Other: Ice Packs;   Drug: Tylenol;   Drug: Motrin;   Drug: dilaudid
    Sponsor:   MetroHealth Medical Center
    Recruiting
  • A Pilot Study to Assess the Accuracy of Blood Pressure Assessment by the Omron HeartGuide Smartwatch
    NCT03986281
    Conditions:   Hypertension;   Cardiac Disease;   Surgery
    Interventions:   Other: Omron Wearable Device;   Other: Standard Arterial Line
    Sponsor:   The Cleveland Clinic
    Recruiting
  • A Single Session Pain Psychology Class for Spine Surgery Patients
    NCT03985436
    Condition:   Lumbar; Injury
    Intervention:   Behavioral: Trek for Surgical Success
    Sponsor:   Sara Davin, PsyD, MPH
    Enrolling by invitation
  • Daily Living Skills Intervention for 9th and 10th Graders With Autism Spectrum Disorders
    NCT03984513
    Condition:   Autism Spectrum Disorder
    Interventions:   Behavioral: Surviving and Thriving in the Real World;   Behavioral: Program for the Education and Enrichment of Relational Skills
    Sponsors:   Children's Hospital Medical Center, Cincinnati;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Recruiting
  • A Program to Increase Sickle Cell Trait Knowledge Among Parent of Infants Identified in Newborn Screening
    NCT03984500
    Condition:   Sickle Cell Trait
    Intervention:   Other: Education
    Sponsors:   Nationwide Children's Hospital;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
    Recruiting
  • Daily Living Skills Intervention for Adolescents With Autism Spectrum Disorder
    NCT03984487
    Condition:   Autism Spectrum Disorder
    Interventions:   Behavioral: Surviving and Thriving in the Real World;   Behavioral: Program for the Education and Enrichment of Relational Skills
    Sponsors:   Children's Hospital Medical Center, Cincinnati;   United States Department of Defense
    Recruiting
  • IPACK Versus Popliteal Sciatic Nerve Block in ACL Reconstruction
    NCT03983941
    Condition:   Anterior Cruciate Ligament Tear
    Intervention:   Drug: Ropivacaine injection
    Sponsor:   Sujana Dontukurthy
    Enrolling by invitation
  • Efficacy and Application of the Alfred SmartBag System After Ileostomy Creation in Colorectal Surgery: A Pilot Study
    NCT03982875
    Conditions:   Ileostomy - Stoma;   Ileostomy; Complications
    Intervention:   Device: Alfred SmartBag
    Sponsors:   11 Heath and Technologies Limited;   The Cleveland Clinic
    Recruiting
  • Innovations to Prevent Relapse Among Low-income African American Smokers
    NCT03982576
    Condition:   Smoking Cessation
    Interventions:   Other: Nicotine replacement therapy (NRT);   Behavioral: CS-CBT intervention;   Behavioral: Path2Quit;   Behavioral: Relapse prevention program;   Behavioral: SmokefreeTXT
    Sponsor:   Case Comprehensive Cancer Center
    Not yet recruiting
  • Dietary Supplementation in Heart Failure
    NCT03980574
    Condition:   Heart Failure
    Intervention:   Dietary Supplement: R Drink
    Sponsors:   Ohio State University;   Vascular Scientific, LLC
    Recruiting
  • A Pilot Study of KPL-914 in Recurrent Pericarditis
    NCT03980522
    Condition:   Recurrent Pericarditis
    Intervention:   Drug: KPL-914
    Sponsor:   Kiniksa Pharmaceuticals, Ltd.
    Completed
  • Trial of Blood Flow Restriction Plus Physical Therapy vs. Physical Therapy Alone for Lateral Epicondylitis
    NCT03978897
    Condition:   Lateral Epicondylitis
    Interventions:   Device: Blood flow restriction tourniquet;   Other: Evidence based physical/occupational therapy
    Sponsor:   Akron General Medical Center
    Recruiting
  • Dual-benefits of Aerobic and Resistance Training
    NCT03978572
    Conditions:   Sarcopenia;   Aging;   Disability Physical
    Interventions:   Behavioral: Resistance Training;   Behavioral: Moderate-Intensity Continuous Cycling;   Behavioral: High-Intensity Interval Cycling
    Sponsors:   Ohio University;   American Heart Association
    Recruiting
  • Dabrafenib, Trametinib, and IMRT in Treating Patients With BRAF Mutated Anaplastic Thyroid Cancer
    NCT03975231
    Conditions:   BRAF NP_004324.2:p.V600E;   BRAF V600K Mutation Present;   Thyroid Gland Anaplastic Carcinoma
    Interventions:   Drug: Dabrafenib;   Radiation: Intensity-Modulated Radiation Therapy;   Drug: Trametinib
    Sponsors:   Manisha Shah;   National Cancer Institute (NCI)
    Not yet recruiting
  • Gut-level Antiinflammatory Activities of Green Tea in Metabolic Syndrome
    NCT03973996
    Conditions:   Dysbiosis;   Endotoxemia;   Metabolic Syndrome;   Inflammation
    Interventions:   Dietary Supplement: Green Tea Extract;   Dietary Supplement: Placebo
    Sponsors:   Ohio State University;   USDA Beltsville Human Nutrition Research Center
    Recruiting
  • Parastomal Hernia Repair Utilizing the Retromuscular Sugarbaker Versus Keyhole Mesh Techniques
    NCT03972553
    Condition:   Parastomal Hernia
    Interventions:   Procedure: Sugarbaker technique for repairing parastomal hernia;   Procedure: Keyhole technique for repairing parastomal hernia
    Sponsor:   The Cleveland Clinic
    Recruiting
  • A Problem Solving Intervention for Post-ICU Cognitive Impairment in Older Adults
    NCT03972384
    Conditions:   Critical Illness;   Mechanical Ventilation Complication;   Delirium;   Cognitive Impairment
    Intervention:   Behavioral: Post-ICU Problem Solving
    Sponsor:   Ohio State University
    Not yet recruiting
  • Meta-analysis of Stannous Fluoride and the Effects on Gingival Health
    NCT03970759
    Condition:   Gingivitis
    Interventions:   Drug: Stannous Fluoride Dentifrice;   Drug: Positive control dentifrice;   Drug: Negative control dentifrice
    Sponsor:   Procter and Gamble
    Completed
  • Evaluation of Step-Based Care for Individuals at Clinical High Risk for Psychosis
    NCT03970005
    Condition:   Prodromal Schizophrenia
    Intervention:   Behavioral: Step-Based Care Model
    Sponsors:   Ohio State University;   Substance Abuse and Mental Health Services Administration (SAMHSA)
    Enrolling by invitation
  • Oral Ketorolac for Arthroscopic Rotator Cuff Repair
    NCT03967847
    Conditions:   Rotator Cuff Tear;   Postoperative Pain
    Intervention:   Drug: Ketorolac
    Sponsor:   University Hospitals Cleveland Medical Center
    Recruiting
  • TRPV2 Agonists in the Fontan Circulation
    NCT03965351
    Condition:   Fontan
    Intervention:   Drug: Probenecid
    Sponsors:   Children's Hospital Medical Center, Cincinnati;   American Heart Association
    Active, not recruiting
  • Kidney Fibrosis and MRI
    NCT03964948
    Condition:   Kidney Diseases
    Intervention:   Diagnostic Test: Kidney MRI
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Recruiting
  • Effect of One-lung Ventilation on BIS Values
    NCT03962036
    Conditions:   Surgery;   Thoracic
    Intervention:   Device: Bispectral index monitor
    Sponsor:   Christopher McKee
    Enrolling by invitation
  • Cancer Activity and Lifestyle Measurement Study
    NCT03961685
    Condition:   Breast Cancer
    Intervention:  
    Sponsor:   Ohio State University
    Recruiting
  • Glycemic Characterization and Pancreatic Imaging Correlates in Cystic Fibrosis
    NCT03961516
    Conditions:   Cystic Fibrosis;   Cystic Fibrosis-related Diabetes;   Cystic Fibrosis Liver Disease;   Pancreatic Steatosis;   Hepatic Steatosis
    Interventions:   Device: Frequently Sampled Oral Glucose Tolerance Test and CGM;   Radiation: MRI Pancreas and Liver
    Sponsor:   University Hospitals Cleveland Medical Center
    Recruiting
  • Gadoxetate Sodium Enhanced MRI as a Biomarker for Aggressive Prostate Cancer
    NCT03960788
    Conditions:   Cancer of the Prostate;   Castration-resistant Prostate Cancer
    Intervention:   Drug: Gadoxetate Sodium
    Sponsor:   University of Cincinnati
    Recruiting
  • Photodynamic Therapy and Microvesicles
    NCT03960125
    Conditions:   Photodynamic Therapy;   Microvesicle Particle
    Interventions:   Device: Photodynamic Therapy;   Drug: 4% Imipramine;   Drug: Base Cream
    Sponsor:   Jeffrey B. Travers, MD, PhD
    Not yet recruiting
  • Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain
    NCT03959852
    Condition:   Pain, Acute
    Interventions:   Drug: Fentanyl;   Combination Product: Fentanyl and Ketamine;   Drug: Ketamine
    Sponsor:   Mercy Health Ohio
    Recruiting
  • Behavioral Economics and Adherence in Teens (BEAT!)
    NCT03958331
    Conditions:   Epilepsy;   Adherence, Medication
    Interventions:   Behavioral: Automated Digital Reminders;   Behavioral: Individualized Adherence Feedback Report;   Behavioral: Individual Adherence Feedback Report with Social Norms
    Sponsors:   Children's Hospital Medical Center, Cincinnati;   National Institute of Nursing Research (NINR);   Nationwide Children's Hospital
    Not yet recruiting
  • OT Via Telehealth (ASD and ADHD)
    NCT03957993
    Conditions:   Autism Spectrum Disorder;   Attention Deficit Hyperactivity Disorder
    Interventions:   Other: Occupational Therapy via Telehealth;   Other: Standard of Care Occupational Therapy
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Recruiting
  • Remote Access: Cortical Visual Impairment
    NCT03957980
    Condition:   Cortical Visual Impairment
    Intervention:   Other: Occupational therapy
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Completed
  • CPX-351 Therapy for MDS After Hypomethylating Agent Failure
    NCT03957876
    Condition:   Myelodysplastic Syndrome (MDS)
    Intervention:   Drug: CPX-351
    Sponsor:   Case Comprehensive Cancer Center
    Recruiting
  • Evaluation of the Prenatal Trip Assistance Pilot Project
    NCT03956810
    Conditions:   Pregnancy Preterm;   Infant Death
    Interventions:   Other: On-demand transportation;   Other: Usual transportation
    Sponsor:   Ohio State University
    Recruiting
  • Cardiovascular Outcomes in Bariatric Surgery Patients With Type 2 Diabetes
    NCT03955952
    Conditions:   Obesity;   Type2 Diabetes;   Bariatric Surgery Candidate
    Intervention:   Procedure: Bariatric Surgery
    Sponsor:   The Cleveland Clinic
    Enrolling by invitation
  • AveXis Managed Access Program Cohort for Access to AVXS-101
    NCT03955679
    Condition:   Spinal Muscular Atrophy
    Intervention:   Genetic: AVXS-101
    Sponsors:   United BioSource Corporation;   AveXis, Inc.
    Approved for marketing
  • Healthy Relationships Training Study: A Comparison of Interventions to Reduce Dating Violence on College Campuses
    NCT03950128
    Condition:   Dating Violence
    Interventions:   Behavioral: Mindfulness-Based Skills Training (MBST);   Behavioral: Psychoeducational
    Sponsor:   Kent State University
    Completed
  • Free Flap Breast Reconstruction Using Virtual Surgical Planning and 3-D Modeling
    NCT03949491
    Condition:   Breast Reconstruction
    Intervention:   Procedure: 3D medical models
    Sponsor:   Case Comprehensive Cancer Center
    Not yet recruiting
  • Ultrasound Assessment of the Inferior Vena Cava in Children
    NCT03948282
    Condition:   Surgery
    Intervention:  
    Sponsor:   Alok Moharir
    Completed
  • Efficacy of Baricitinib In Treatment of Delayed-Type Hypersensitivity Versus Irritant Skin Reactions in Healthy Adult Male Subjects
    NCT03945760
    Condition:   Allergic Contact Dermatitis
    Interventions:   Drug: Baricitinib;   Drug: Placebo
    Sponsor:   Wright State Physicians
    Not yet recruiting
  • CT-P13 (Infliximab) Subcutaneous Administration in Patients With Moderately to Severely Active Crohn's Disease
    NCT03945019
    Condition:   Crohn's Disease
    Interventions:   Biological: CT-P13 SC (Infliximab);   Other: Placebo SC
    Sponsor:   Celltrion
    Recruiting
  • Ibrutinib and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia After Ibrutinib Resistance
    NCT03943342
    Conditions:   Chronic Lymphocytic Leukemia;   Loss of Chromosome 17p
    Interventions:   Drug: Ibrutinib;   Drug: Venetoclax
    Sponsors:   Kerry Rogers;   National Cancer Institute (NCI);   Janssen Research & Development, LLC
    Not yet recruiting
  • Proton Accelerated Partial Breast Irradiation
    NCT03940248
    Condition:   Breast Cancer
    Intervention:   Radiation: Proton Accelerated Partial Breast Irradiation
    Sponsor:   University of Cincinnati
    Enrolling by invitation
  • Preemptive Infusion of Donor Lymphocytes Depleted of TCR + T Cells + CD19+ B Cells Following ASCT
    NCT03939585
    Conditions:   Allogeneic Stem Cell Transplant Candidate;   Acute Myeloid/Lymphoblastic Leukemia;   Myelodysplastic Syndrome;   Myeloproliferative Neoplasm;   Lymphoproliferative Disorders
    Intervention:   Biological: Cellular therapy product
    Sponsor:   Case Comprehensive Cancer Center
    Not yet recruiting
  • Randomized Control Trial Comparing Transfascial Suture for Mesh Fixation to No Mesh Fixation
    NCT03938688
    Conditions:   Ventral Hernia;   Incisional Hernia
    Intervention:   Procedure: Mesh placement with Transfascial Sutures
    Sponsor:   The Cleveland Clinic
    Recruiting
  • The Renin-Angiotensin-Aldosterone System in Adiposity, Blood Pressure and Glucose in African Americans
    NCT03938389
    Conditions:   PreDiabetes;   Impaired Glucose Tolerance;   Obesity;   Blood Pressure
    Interventions:   Drug: Sacubitril-Valsartan Tab 97-103 MG;   Drug: Valsartan 160mg;   Drug: Placebo Oral Tablet
    Sponsors:   Ohio State University;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    Not yet recruiting
  • Calcitonin Pre-treatment to Improve SPECT-CT Sensitivity
    NCT03935984
    Conditions:   Primary Hyperparathyroidism;   Hypercalcemia
    Intervention:   Drug: Calcitonin
    Sponsors:   ProMedica Health System;   University of Toledo Health Science Campus
    Recruiting
  • Motivational Interviewing and Vaccine Hesitancy in Children
    NCT03934008
    Condition:   Vaccine Hesitancy
    Intervention:   Other: MOtivational interviewing Tool to Improve Vaccine AdherencE (MOTIVE)
    Sponsors:   Cedarville University;   Merck Investigator Studies Program;   Rocking Horse Community Health Center
    Recruiting
  • Study Assessing Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MGTA-145 in Healthy Volunteers as a Single Agent or in Combination With Plerixafor
    NCT03932864
    Condition:   Healthy Volunteers
    Interventions:   Biological: MGTA-145;   Biological: plerixafor;   Biological: Placebo
    Sponsor:   Magenta Therapeutics, Inc.
    Recruiting
  • Gene Expression Changes In Young and Geriatric Skin
    NCT03932162
    Conditions:   UVB Phototherapy Burn;   Insulin-like Growth Factor 1;   Aging
    Interventions:   Drug: Insulin-Like Growth Factor 1;   Other: No Insulin-Lie Growth Factor 1
    Sponsor:   Jeffrey B. Travers, MD, PhD
    Recruiting
  • Collaborating to Implement Cross-System Interventions in Child Welfare and Substance Use
    NCT03931005
    Conditions:   Substance Use;   Implementation;   Child Maltreatment;   System Fragmentation
    Interventions:   Other: Collaboration Decision Support Guide;   Other: General Collaboration Support
    Sponsor:   Ohio State University
    Not yet recruiting
  • 18F-Fluciclovine PET to Distinguish Tumor Progression From Radiation Necrosis
    NCT03930173
    Condition:   Secondary Malignant Neoplasm of Brain and Cerebral Meninges
    Interventions:   Drug: 18F-fluciclovine;   Device: PET/CT of the brain
    Sponsor:   Case Comprehensive Cancer Center
    Recruiting
  • Liposomal Bupivacaine Versus Interscalene Nerve Block
    NCT03929146
    Condition:   Pain, Postoperative
    Interventions:   Drug: Exparel;   Procedure: Interscalene Nerve Block
    Sponsor:   University of Cincinnati
    Recruiting
  • Feasibility of a Culturally-Specific Video Text Cessation Intervention With AA Quitline Callers
    NCT03927976
    Condition:   Tobacco Use Cessation
    Intervention:   Behavioral: Path2Quit - culturally specific text message intervention
    Sponsor:   Case Comprehensive Cancer Center
    Not yet recruiting
  • GSNOR Phenotyping/GSNO Challenge
    NCT03926741
    Conditions:   Asthma;   Healthy Volunteers
    Intervention:   Drug: GSNO
    Sponsors:   James Reynolds;   University Hospitals Cleveland Medical Center;   Case Western Reserve University;   National Heart, Lung, and Blood Institute (NHLBI)
    Recruiting
  • Screening for Systemic Amyloidosis Via the Ligamentum Flavum
    NCT03923920
    Conditions:   Amyloid;   Amyloidosis;   Spinal Stenosis;   Transthyretin Amyloidosis;   Primary Amyloidosis of Light Chain Type
    Intervention:   Procedure: Biopsy
    Sponsor:   The Cleveland Clinic
    Recruiting
  • Pelvic Floor Muscle Training With Leva System for Urge Incontinence
    NCT03923348
    Conditions:   Overactive Bladder;   Urge Urinary Incontinence;   Mixed Urinary Incontinence
    Intervention:   Device: Leva device
    Sponsors:   The Christ Hospital;   Renovia, Inc.
    Recruiting
  • Study of the Safety and Efficacy of DPI-386 Nasal Gel on Ocean-Going Vessels
    NCT03920644
    Conditions:   Prevention of Nausea Associated With Motion Sickness;   Treatment of Nausea Associated With Motion Sickness
    Interventions:   Drug: Scopolamine Transdermal Patch [Transderm Scop];   Drug: Scopolamine;   Drug: Placebo Patch;   Drug: Placebo Gel
    Sponsor:   Naval Aeromedical Research Unit, Dayton
    Recruiting
  • A Clinical Study of the Eztetic Dental Implant System
    NCT03917927
    Condition:   Edentulous Jaw
    Intervention:   Device: Eztetic dental implant
    Sponsor:   Zimmer Biomet
    Recruiting
  • Older Adult Effectiveness of 2 Treatments
    NCT03916926
    Condition:   Dental Caries
    Interventions:   Device: A "simple medical strategy" consisting of silver diamine fluoride (SDF);   Device: B "typical dental strategy" consisting of atraumatic restorative treatment (ART) with glass ionomer cement + Fluoride varnish (FV)
    Sponsors:   Case Western Reserve University;   Patient-Centered Outcomes Research Institute
    Not yet recruiting
  • Registry and Screening Tool to Identify Children With Asthma Likely to Benefit From Home Assessment and Remediation
    NCT03916237
    Conditions:   Asthma;   Pediatric ALL;   School Health Services;   Registries;   Medical Informatics;   Home Visits;   Housing Problems;   Social Determinants of Health;   Healthcare Disparity;   Health Status Disparity
    Interventions:   Other: Home assessment;   Other: Home remediation;   Other: Referral to Medical Legal Partnership;   Other: Asthma SDH screening tool
    Sponsors:   MetroHealth Medical Center;   Cleveland Metropolitan School District;   Environmental Health Watch;   Legal Aid Society of Cleveland
    Not yet recruiting
  • Fuzzy AI Using VR for Collision Prevention
    NCT03915119
    Condition:   Injuries
    Intervention:   Other: GFT AI training
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Active, not recruiting
  • Fontan Associated Liver Disease
    NCT03914196
    Condition:   Fontans
    Intervention:   Diagnostic Test: Liver Stiffness Ultrasound
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Recruiting
  • Effects of Neuromuscular Training on EEG Adaptations in Young Athletes
    NCT03913975
    Condition:   Brain Concussion
    Intervention:   Other: Neuromuscular training
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Completed
  • Hemoglobin Desaturation in Sickle Cell Disease
    NCT03908385
    Condition:   Sickle Cell Disease
    Intervention:  
    Sponsor:   University Hospitals Cleveland Medical Center
    Recruiting
  • Liposomal Bupivacaine After Cesarean Delivery
    NCT03907813
    Conditions:   Pain, Postoperative;   Opioid Use
    Interventions:   Drug: Exparel;   Other: Saline infiltration
    Sponsor:   Wright State University
    Not yet recruiting
  • Advance Care Planning GuideTailored for Primary Care Patients
    NCT03906773
    Conditions:   Advance Care Planning;   Chronic Disease;   Communication Research
    Intervention:   Other: Patient Centered Medical Home Based Electronic Framework for Advance Care Planning
    Sponsor:   Ohio State University
    Completed
  • Effectiveness of Fractionated Laser Resurfacing to Protect Geriatric Skin From Actinic Neoplasia
    NCT03906253
    Conditions:   Actinic Keratoses;   Aging;   Non-Melanoma Skin Cancer
    Intervention:   Device: Fractionated Laser Resurfacing
    Sponsor:   Jeffrey B. Travers, MD, PhD
    Recruiting
  • Identification of microRNAs Involved in Cerebral Collateral Regulation
    NCT03905434
    Condition:   Cerebrovascular Disorders
    Intervention:   Genetic: miRNA sampling
    Sponsor:   Ohio State University
    Recruiting
  • Defining the Operating Characteristics of NIRS in the Diagnosis of Pediatric Traumatic Intracranial Hemorrhage
    NCT03905031
    Conditions:   Craniocerebral Injuries;   Head Injuries;   Head Injury, Minor;   Head Trauma;   Traumatic Brain Injury;   Traumatic Brain Hemorrhage;   Hematoma of Head;   Intracranial Hemorrhages
    Intervention:   Device: InfraScanner 2000
    Sponsor:   Dayton Children's Hospital
    Recruiting
  • Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery
    NCT03904862
    Condition:   Medulloblastoma, Childhood
    Intervention:   Drug: CX 4945
    Sponsors:   Pediatric Brain Tumor Consortium;   St. Jude Children's Research Hospital;   National Cancer Institute (NCI)
    Recruiting
  • Post-partum Non-pharmacologic Pain Management
    NCT03903172
    Conditions:   Pain Management;   Vaginal Delivery
    Intervention:   Device: Abdominal binder
    Sponsor:   Wright State University
    Enrolling by invitation
  • Optical Treatment of Migraines Using the Avulux™ Optical Filter in the Form of Spectacle Lenses.
    NCT03902496
    Condition:   Migraine
    Interventions:   Other: HIT-6 Questionnaire;   Device: Avulux Spectacles;   Device: Sham Spectacles
    Sponsor:   Avulux, Inc.
    Completed
  • A Protein-sparing Modified Fast for Children and Adolescents With Severe Obesity (PSMF)
    NCT03899311
    Condition:   Obesity, Childhood
    Intervention:   Other: protein-sparing modified fast diet
    Sponsor:   Ihuoma Eneli
    Completed
  • An Early Feasibility Study of the ReHAB System
    NCT03898804
    Condition:   Tetraplegia
    Intervention:   Device: BCI and FES
    Sponsor:   Jonathan Miller, MD
    Recruiting
  • The Effect of Psychologically Informed Education in Adolescents With Anterior Knee Pain
    NCT03897907
    Conditions:   Patellofemoral Pain Syndrome;   Anterior Knee Pain Syndrome
    Interventions:   Other: Psychologically Informed Education Video;   Other: Anatomy Education Video
    Sponsor:   Nationwide Children's Hospital
    Recruiting
  • Safety & Immunogenicity Study of Ad5 Based Oral Norovirus Vaccines
    NCT03897309
    Condition:   Norovirus Infection
    Interventions:   Biological: VXA-G1.1-NN;   Biological: VXA-G2.4-NS;   Biological: Placebo Tablets
    Sponsor:   Vaxart
    Recruiting
  • Efficacy and Safety of Tildrakizumab in the Treatment of Scalp Psoriasi
    NCT03897088
    Condition:   Scalp Psoriasis
    Interventions:   Drug: Tildrakizumab;   Drug: Placebo
    Sponsor:   Sun Pharma Global FZE
    Recruiting
  • Supermarket and Web-Based Intervention Targeting Nutrition (SuperWIN) for Cardiovascular Risk Reduction
    NCT03895580
    Conditions:   Obesity;   Hypertension;   Hyperlipidemias;   Diet Modification
    Interventions:   Other: In-store POP education;   Other: Online POP education
    Sponsors:   University of Cincinnati;   The Kroger Company;   Children's Hospital Medical Center, Cincinnati
    Recruiting
  • Use of Lumbar Motion Monitor to Predict Response to Radiofrequency Ablation After Medial Branch Diagnostic Blocks
    NCT03894319
    Condition:   Back Pain
    Intervention:  
    Sponsor:   Ohio State University
    Recruiting
  • Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene
    NCT03892798
    Conditions:   Neurodevelopmental Regression, Seizures, Autism and Developmental Delay (NEDAMSS);   Autism Spectrum Disorder;   Movement Disorders;   Seizures;   Dystonia
    Intervention:   Other: No interventions are planned
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Recruiting
  • Duvelisib and Nivolumab in Treating Patients With Richter Syndrome or Transformed Follicular Lymphoma
    NCT03892044
    Conditions:   Chronic Lymphocytic Leukemia;   Recurrent Diffuse Large B-Cell Lymphoma;   Refractory Diffuse Large B-Cell Lymphoma;   Richter Syndrome;   Small Lymphocytic Lymphoma;   Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma;   Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma;   Transformed Small Lymphocytic Lymphoma to Diffuse Large B-Cell Lymphoma
    Interventions:   Drug: Duvelisib;   Biological: Nivolumab
    Sponsors:   Jennifer Woyach;   National Cancer Institute (NCI)
    Recruiting
  • Intestinal Microbiome Composition in Infants With Biliary Atresia (BA)
    NCT03890536
    Conditions:   Biliary Atresia;   Intrahepatic Cholestases;   Normal Controls
    Intervention:  
    Sponsors:   Children's Hospital Medical Center, Cincinnati;   Wuhan Union Hospital, China
    Not yet recruiting
  • Phase IB Metformin, Digoxin, Simvastatin in Solid Tumors
    NCT03889795
    Conditions:   Advanced Pancreatic Cancer;   Advanced Solid Tumor
    Interventions:   Drug: Metformin;   Drug: Simvastatin;   Drug: Digoxin
    Sponsor:   John Nemunaitis, MD
    Recruiting
  • Study of Ketorolac Versus Opioid for Pain After Endoscopy
    NCT03888144
    Conditions:   Kidney Calculi;   Ureteral Calculi
    Interventions:   Drug: Oxycodone;   Drug: Ketorolac
    Sponsor:   The Cleveland Clinic
    Recruiting
  • A Systematic Oral Care Program in Post-Mechanically Ventilated, Post-Intensive Care Patients
    NCT03886623
    Conditions:   Methicillin-resistant Staphylococcus Aureus;   Methicillin-Sensitive Staphylococcus Aureus Infection
    Interventions:   Procedure: 4-day systematic oral hygiene;   Other: Standard of Care oral care
    Sponsor:   Ohio State University
    Completed
  • Cardiac Amyloidosis Screening at Trigger Finger Release
    NCT03886155
    Conditions:   Amyloidosis;   Trigger Finger;   Transthyretin Amyloidosis;   Primary Amyloidosis of Light Chain Type
    Intervention:   Procedure: Biopsy
    Sponsor:   The Cleveland Clinic
    Recruiting
  • Efficacy of the Dabir Surfaces Micropressure Overlay for Decubitus Ulcer Prevention During Cardiac Surgery
    NCT03884634
    Conditions:   Pressure Ulcer;   Pressure Injury
    Intervention:   Device: Dabir Micropressure Overlay
    Sponsor:   The Cleveland Clinic
    Recruiting
  • Cysteamine for Asthma
    NCT03883984
    Condition:   Asthma
    Interventions:   Drug: Cysteamine Bitartrate;   Drug: Placebo Oral Tablet
    Sponsor:   Children's Hospital Medical Center, Cincinnati
    Recruiting
  • Donor-Derived Viral Specific T-cells (VSTs) for Prophylaxis Against Viral Infections After Allogeneic Stem Cell Transplant
    NCT03883906
    Conditions:   Allogeneic Stem Cell Transplant;   Viral Infection
    Intervention:   Biological: Viral Specific T-cells (VSTs)
    Sponsors:   Children's Hospital Medical Center, Cincinnati;   Hoxworth Blood Center
    Recruiting

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