Condition: Spinal Cord Injuries Intervention: Device: Transcutaneous Spinal Stimulation Sponsors: University of Louisville; National Center of Neuromodulation for Rehabilitation (NM4R) Not yet recruiting
Conditions: Hepatitis C; Opioid-Related Disorders; Injection Drug Use Intervention: Drug: Sofosbuvir/velpatasvir (Epclusa®) Sponsors: Jennifer Havens; National Institute on Drug Abuse (NIDA); National Cancer Institute (NCI); Gilead Sciences; University of Kentucky; Icahn School of Medicine at Mount Sinai; University of Bristol Not yet recruiting
Conditions: Neurosciences; Substance-Related Disorders; Behavior Problem Interventions: Drug: Marinol; Device: Transcranial Magnetic Stimulation Sponsor: University of Kentucky Recruiting
Condition: Knee Arthropathy Interventions: Other: Primary Robotic-Assisted Total Knee Arthroplasty without the use of a tourniquet; Other: Primary Robotic-Assisted Total Knee Arthroplasty with the use of a tourniquet Sponsor: University of Louisville Not yet recruiting
Conditions: Labor Pain; Contraction Intervention: Device: Fetal Life tocometer device Sponsors: Fetal Life LLC; University of Louisville Not yet recruiting
Condition: Cocaine Use Disorder Interventions: Drug: Suvorexant; Drug: Cocaine; Drug: Placebo oral capsule Sponsors: William Stoops; National Institute on Drug Abuse (NIDA) Not yet recruiting
Condition: Alcoholic Hepatitis Interventions: Drug: DUR-928 (Moderate AH); Drug: DUR-928 (Severe AH) Sponsors: Craig James McClain; National Institute on Alcohol Abuse and Alcoholism (NIAAA) Not yet recruiting
Conditions: Tibial Fractures; Nonunion of Fracture; Delayed Union of Fracture Intervention: Procedure: Intramedullary Bone Graft Sponsor: University of Louisville Not yet recruiting
Condition: Knee Arthropathy Interventions: Other: ACB + IPACK block with injection of local anesthetic; Other: ACB + IPACK block without injection Sponsor: University of Louisville Not yet recruiting
Condition: Oral Health Intervention: Behavioral: Oral health promotion strategy Sponsors: University of Louisville; National Institute of Dental and Craniofacial Research (NIDCR) Enrolling by invitation
Condition: Patients Undergoing Cardiac Angiography Who Are at Risk for Contrast Induced Acute Kidney Injury Intervention: Device: DyeVert™ Contrast Reduction Systems Sponsor: Osprey Medical, Inc Enrolling by invitation
Condition: Smoking Cessation Interventions: Behavioral: Behavioral and Enhanced Perinatal Intervention for Cessation (B-EPIC); Behavioral: Treatment As Usual Sponsors: Kristin Ashford; National Institute on Drug Abuse (NIDA) Recruiting
Condition: Treatment Resistant Depression Interventions: Other: Discontinuation of serotonergic antidepressants; Other: Continuation of serotonergic medications Sponsor: University of Louisville Not yet recruiting
Conditions: Neuroendocrine Tumors; Carcinoid Tumor of GI System; Diarrhea; Carcinoid Syndrome Intervention: Dietary Supplement: Amino Acid Based Medical Food/Drink Sponsors: University of Kentucky; Entrinsic Health Solutions, Inc. Recruiting
Condition: Familial Amyotrophic Lateral Sclerosis Intervention: Drug: Betamethasone sodium phosphate/betamethasone acetate (Celestone® Soluspan®), 30 mg IM once a day for four days Sponsor: University of Kentucky Recruiting
Condition: Suicide and Self-harm Intervention: Behavioral: CAMS-G Sponsors: Louisville VA Medical Center; Rocky Mountain MIRECC for Suicide Prevention Recruiting
Conditions: Cardiovascular Diseases; Metabolic Health Intervention: Other: Greenness as a therapeutic intervention Sponsors: University of Louisville; National Institute of Environmental Health Sciences (NIEHS); The Nature Conservancy Recruiting
Conditions: Osteoarthritis Elbow Left; Osteoarthritis Elbow Right; Lateral Epicondylitis, Left Elbow; Lateral Epicondylitis, Right Elbow; Plica Syndromes; Osteochondritis Dissecans Intervention: Sponsor: The Orthopaedic Research & Innovation Foundation Active, not recruiting
Condition: Wave Form Signals Coming From the Eye in a Healthy Cohort Intervention: Device: HITT device Sponsors: Rebiscan, Inc.; BlueGrass Orthopaedics Surgery & Hand Care Completed
Conditions: Renal Insufficiency, Chronic; Anemia, Iron Deficiency; Anemia of Chronic Kidney Disease Intervention: Device: Model predictive control Sponsor: University of Louisville Not yet recruiting
Conditions: Total Shoulder Arthroplasty; Osteo Arthritis Shoulders Intervention: Procedure: posterior approach to total shoulder arthroplasty Sponsor: The Orthopaedic Research & Innovation Foundation Active, not recruiting
Condition: Recession, Gingival Interventions: Procedure: Flap Surgery for root coverage with Alloderm and xenograft; Procedure: Tunnel Surgery for root coverage with Alloderm and xenograft Sponsor: University of Louisville Not yet recruiting
Condition: Alcohol Use Disorder Interventions: Drug: Alcohol; Drug: Placebos; Drug: Duloxetine; Drug: Methylphenidate Sponsors: Craig Rush; National Institute on Alcohol Abuse and Alcoholism (NIAAA) Recruiting
Condition: Dietary Habits Intervention: Behavioral: Walking Group Sponsors: Dawn Brewer; National Institute of Environmental Health Sciences (NIEHS) Completed
Condition: Heart Failure Interventions: Behavioral: Family SWaP intervention with mini iPad; Behavioral: usual care Sponsor: Misook L. Chung Recruiting
Conditions: Spinal Cord Injuries; Neurogenic Bladder Intervention: Procedure: Locomotor Training Sponsors: University of Louisville; The Leona M. and Harry B. Helmsley Charitable Trust; Kosair Charities, Inc. Recruiting
Condition: Suicide, Attempted Intervention: Behavioral: Teachable Moment Brief Intervention Sponsors: Louisville VA Medical Center; University of Louisville Recruiting
Condition: Cocaine Use Disorder Interventions: Drug: Cocaine; Drug: Placebo oral capsule; Drug: Methylphenidate Sponsors: Craig Rush; National Institute on Drug Abuse (NIDA) Recruiting
Conditions: Pregnancy Related; Obesity Intervention: Other: Physical Activity Education and Resources Sponsor: Western Kentucky University Active, not recruiting
Condition: Subacute Low Back Pain Interventions: Behavioral: Progressive Exercise Plan; Device: NeuromuscularElectricalStimulation(NMES); Behavioral: Primary Care Management (PCM) Sponsors: University of Tennessee; Blanchfield Army Community Hospital Recruiting
Condition: Alcohol-Impaired Driving Interventions: Behavioral: Personalized feedback; Behavioral: Personalized feedback and text messages; Behavioral: Information Only Sponsor: Western Kentucky University Enrolling by invitation
Condition: Dietary Habits Interventions: Behavioral: walking group led by a community organizer; Behavioral: Drive Sponsors: Dawn Brewer; National Institute of Environmental Health Sciences (NIEHS) Completed
Conditions: Hearing Loss; Behavior Disorders; Parenting Interventions: Behavioral: Interventionist training and supervision; Behavioral: Behavioral parent training Sponsor: University of Kentucky Completed
Condition: Cardiovascular Risk Factor Intervention: Behavioral: Blackberry Consumption Sponsors: Dawn Brewer; National Institute of Environmental Health Sciences (NIEHS) Active, not recruiting
Condition: Colorectal Cancer Interventions: Behavioral: Motivational interview; Behavioral: Standard of care Sponsor: University of Kentucky Recruiting
Conditions: Physical Activity; Surgery; Vaginal Hysterectomy; Vaginal Surgery Intervention: Procedure: Vaginal Surgery Sponsor: University of Louisville Recruiting
Condition: Pregnancy Interventions: Behavioral: ToPIC; Behavioral: Tobacco Treatment As Usual (TTAU) Sponsors: Kristin Ashford; University of Kentucky Active, not recruiting
Condition: Alcohol Use Disorder Interventions: Behavioral: Normative Feedback; Behavioral: Inhibitory Control Training; Behavioral: Working Memory Training Sponsors: Craig Rush; National Institute on Drug Abuse (NIDA) Recruiting
Condition: Neonatal Abstinence Syndrome Interventions: Drug: Clonidine; Drug: Morphine Sponsors: University of Kentucky; National Institute on Drug Abuse (NIDA) Recruiting
Condition: Chemotherapy-induced Cognitive Impairment Intervention: Behavioral: Neurocognitive assessments Sponsors: University of Kentucky; Office of US Army Medical Research and Material Command Recruiting
Conditions: Smoking Cessation; Social Stress Interventions: Behavioral: Social Support; Drug: NRT Sampling Sponsors: Jessica Burris; Kentucky Lung Cancer Research Program Recruiting
Conditions: Non-small Cell Lung Cancer; Squamous Cell Carcinoma of the Head and Neck Interventions: Drug: Immune checkpoint inhibitor; Radiation: Radiation Therapy Sponsor: John L. Villano, MD, PhD Recruiting
Condition: Psychomotor Impairment Interventions: Drug: Alprazolam; Drug: Zolpidem; Drug: Placebo Sponsors: Marion Coe; National Institute on Drug Abuse (NIDA) Completed
Condition: Colo-rectal Cancer Intervention: Behavioral: Now I'm Telling You Sponsors: Richard Crosby; Centers for Disease Control and Prevention Completed
Condition: Cocaine Use Disorder Intervention: Behavioral: Contingency Management Sponsors: William Stoops; National Institute on Drug Abuse (NIDA) Recruiting
Conditions: Atrial Fibrillation; Lung Transplant; Complications Interventions: Drug: Amiodarone with CoSeal; Device: CO2 driver Sponsor: University of Louisville Recruiting
Condition: Alcohol Use Disorder Interventions: Drug: Alcohol; Drug: Placebos; Drug: N-acetyl cysteine Sponsors: William Stoops; National Institute on Alcohol Abuse and Alcoholism (NIAAA) Recruiting
Conditions: Risk Reduction Behavior; Diabetes Mellitus, Type 2; Cardiovascular Diseases Interventions: Behavioral: Family-focused intervention arm; Behavioral: Individual-focused intervention arm Sponsors: University of Kentucky; National Institute of Nursing Research (NINR); National Institutes of Health (NIH) Recruiting
Condition: Injuries Intervention: Behavioral: Cellie Coping Kit Intervention Sponsors: University of Kentucky; Children's Hospital of Philadelphia Recruiting
Conditions: Cancer Cachexia; Vitamin D Deficiency Interventions: Dietary Supplement: Vitamin D; Dietary Supplement: Placebo Sponsor: David Travis Thomas Recruiting
Conditions: Pelvic Organ Prolapse; Prolapse of Vaginal Vault After Hysterectomy; Bulging of Vaginal Wall; Incontinence; Fistula Interventions: Other: Live Surgery using VITOM; Other: Live Surgery without VITOM; Other: Video viewing with VITOM; Other: Video viewing with standard handheld high-definition camera Sponsors: University of Louisville; KARL STORZ Endoscopy-America, Inc. Completed
Condition: Intubation; Difficult Interventions: Device: King Vision video-laryngoscope with #3 disposable blade and endotracheal tube stylet; Device: fiberoptic bronchoscope aScope III Sponsors: University of Louisville; Ambu A/S Recruiting
Condition: Cardiovascular Risk Factor Interventions: Behavioral: RICHH Intervention; Behavioral: Usual care Sponsors: Debra Moser; National Institute of Nursing Research (NINR) Recruiting
Condition: Oxidative Stress Interventions: Dietary Supplement: AT-001; Dietary Supplement: Placebo Sponsors: University of Kentucky; Alltech Life Sciences Inc. Recruiting
Condition: Stage IV Melanoma Interventions: Biological: A-dmDT390-bisFv(UCHT1); Biological: Pembrolizumab; Radiation: Ionizing Radiation Sponsors: Angimmune LLC; James Graham Brown Cancer Center Unknown status
Conditions: Obese; Metabolic Syndrome Interventions: Drug: Mirabegron; Drug: Pioglitazone; Drug: Mirabegron and Pioglitazone Sponsors: Philip Kern; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Recruiting
Condition: Substance Use Disorders Intervention: Behavioral: MCCC treatment Sponsors: Mountain Comprehensive Care Center; University of Kentucky Recruiting
Condition: Subluxation of Joint of Lumbar Spine Interventions: Procedure: Spinal Manipulation; Procedure: Max Voluntary Isometric Contraction; Procedure: SM+MVIC Sponsors: Grant Sanders; University of Kentucky Completed
Conditions: Intermittent Hypoxemia; Acute Kidney Injury; Preterm Infant Intervention: Sponsors: Elie G. Abu Jawdeh, MD; University of Kentucky Active, not recruiting
Conditions: Fluid Responsiveness; Carotid Artery Flow Time; Passive Leg Raise Intervention: Other: Carotid Doppler Measurement in response to passive leg raise Sponsor: University of Louisville Completed
Condition: Cardiovascular Disease Intervention: Other: Observation of SAA on apoB containing lipoproteins Sponsors: Lisa Tannock; VA Office of Research and Development Completed
Condition: Parenting, Child Behavior, Implementation Interventions: Behavioral: behavioral parent training; Behavioral: interventionist training Sponsors: Christina Studts; National Institute of Mental Health (NIMH) Completed
Condition: Cocaine Use Disorder Interventions: Drug: Methylphenidate; Drug: Placebo; Drug: Duloxetine Sponsors: University of Kentucky; National Institute on Drug Abuse (NIDA) Completed
Condition: Depression Interventions: Behavioral: Computer-assisted CBT (CCBT); Other: Treatment as Usual (TAU) Sponsors: University of Louisville; University of Denver; University of York Recruiting
Conditions: Hearing Loss; Hearing Disorders Interventions: Device: Remote CI Counseling; Other: In-Person CI Counseling Sponsor: University of Kentucky Active, not recruiting
Condition: Sexual Violence Interventions: Behavioral: BIC 1; Behavioral: BIC 2; Behavioral: BIC 3 Sponsors: Ann Coker; Centers for Disease Control and Prevention Enrolling by invitation
Condition: Diabetes Mellitus, Type 1 Interventions: Other: text message to parent only; Other: text message to parent and adolescent Sponsor: University of Louisville Withdrawn
Condition: Orthopaedic Surgery Interventions: Other: mHealth application (PoCAH); Other: As usual standard discharge and care instructions Sponsor: Jan Odom Forren Completed
Condition: Patellofemoral Pain Syndrome Interventions: Other: Home Exercise Program (HEP); Device: NMES; Device: TENS Sponsors: University of Tennessee; Blanchfield Army Community Hospital Completed
Conditions: Obese; Normal Body Weight; Prediabetes; Metabolic Syndrome Interventions: Procedure: Fat biopsy; Drug: Propranolol and fat biopsy; Other: heavy water and fat biopsy Sponsors: Philip Kern; National Institutes of Health (NIH) Recruiting
Condition: Sexual Violence Interventions: Behavioral: Green Dot; Behavioral: Wellness Initiatives for Student Empowerment Sponsors: University of Kentucky; Centers for Disease Control and Prevention Completed
Condition: Tobacco Use Intervention: Behavioral: QA-DDS Sponsors: Jamie Studts; National Institute of Dental and Craniofacial Research (NIDCR); University of Alabama at Birmingham; The National Dental Practice-Based Research Network; Health Decision Technologies, LLC Completed
Condition: Chronic Pancreatitis Intervention: Dietary Supplement: acetyl-L-carnitine 1000mg 2X per day for 3 months Sponsors: Karin High; University of Kentucky Terminated
Condition: Cocaine Use Disorder Interventions: Drug: Phendimetrazine; Drug: Cocaine; Drug: Placebo Sponsors: William Stoops; National Institute on Drug Abuse (NIDA) Completed
