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Indiana

• Efficacy of Psychological Therapies in Patients With Functional Bowel Disorders

  NCT04060121

  Conditions:   IBS - Irritable Bowel Syndrome;   Constipation
  Intervention:  
  Sponsors:   Indiana University;   Indiana University Health;   Indiana Clinical and Translational Sciences Institute
  Recruiting
• Bio-mechanical Reasoning and Lateral Specificity of Upper Cervical Joint Mobilization

  NCT04054869

  Condition:   Neck Pain
  Interventions:   Other: Bio-mechanically correct manual therapy at the cervical atlanto-axial joints;   Other: Bio-mechanically in-correct manual therapy at the cervical atlanto-axial joints
  Sponsor:   Andrews University
  Not yet recruiting
• Rhopressa for Corneal Edema Associated With Fuchs Dystrophy

  NCT04051463

  Condition:   Fuchs Endothelial Dystrophy
  Interventions:   Drug: Netarsudil Ophthalmic Solution;   Drug: Placebo
  Sponsor:   Price Vision Group
  Recruiting
• Study of Lonsurf in Combination With Gemcitabine and Nab-Paclitaxel in Patients With Advanced (PDAC)

  NCT04046887

  Conditions:   Pancreatic Cancer;   Pancreatic Ductal Adenocarcinoma
  Interventions:   Drug: Lonsurf;   Drug: Gemcitabine;   Drug: Nab-Paclitaxel
  Sponsors:   Patrick Joseph Loehrer Sr.;   Indiana University;   Taiho Oncology, Inc.
  Not yet recruiting
• Oral Stent Device for Radiation Treatments of Oral Cancers

  NCT04041141

  Conditions:   Tongue Tumor;   Tongue Cancer
  Interventions:   Diagnostic Test: CT Scan;   Device: Experimental Oral Stent Device
  Sponsor:   Indiana University
  Not yet recruiting
• Natural Berry Extract Treatment of Hemangiomas

  NCT04020419

  Condition:   Hemangioma
  Intervention:   Drug: PediaBerry
  Sponsors:   Indiana University;   National Institute of General Medical Sciences (NIGMS);   National Institutes of Health (NIH)
  Not yet recruiting
• Patterned Electric Dressing Effects on Open Wounds

  NCT04018469

  Conditions:   Amputation;   Open Wound
  Intervention:   Other: No Interventions
  Sponsor:   Gayle Gordillo
  Recruiting
• Evaluation of Amphotericin B in Optisol-GS for Prevention of Post-Keratoplasty Fungal Infections.

  NCT04018417

  Condition:   Fuchs' Endothelial Dystrophy
  Intervention:   Drug: Amphotericin B
  Sponsor:   Cornea Research Foundation of America
  Withdrawn
• Clinical Evaluation of Invigor Toric 1-Day Contact Lenses

  NCT04016623

  Condition:   Astigmatism
  Interventions:   Device: 1-day toric test contact lens;   Device: 1-day toric control contact lens
  Sponsor:   Coopervision, Inc.
  Completed
• MDR - Biomet Cannulated Screws

  NCT04002518

  Conditions:   Fractures, Bone;   Fracture Multiple
  Intervention:   Device: Biomet Cannulated Screw: 3.0, 4.0, 5.0, 6.5, and 8.0mm screws.
  Sponsor:   Zimmer Biomet
  Not yet recruiting
• Telephone Support for Metastatic Breast Cancer Patients

  NCT03998618

  Condition:   Metastatic Breast Cancer
  Interventions:   Behavioral: Acceptance and Commitment Therapy;   Behavioral: Education/Support
  Sponsors:   Indiana University;   National Cancer Institute (NCI);   Eskenazi Health
  Recruiting
• Imatinib for Pain in Sickle Cell Anemia

  NCT03997903

  Condition:   Sickle Cell Disease
  Intervention:   Drug: Imatinib Mesylate
  Sponsors:   Indiana University;   Purdue University;   Children's Hospital Medical Center, Cincinnati
  Not yet recruiting
• MOSES Lithotripsy Technology Applied to Stone Fragmentation During Ureteroscopy

  NCT03995758

  Condition:   Kidney Calculi
  Intervention:   Device: MOSES
  Sponsor:   Indiana University
  Recruiting
• G-EO Gait Rehabilitation Training in Progressive Multiple Sclerosis

  NCT03980145

  Condition:   Progressive Multiple Sclerosis
  Interventions:   Device: G-EO System (Reha Technology AG: Olten, Switzerland);   Other: Conventional Physical Therapy
  Sponsors:   Indiana University;   University of Alabama at Birmingham;   University of Ottawa
  Recruiting
• Impact of Social Risk Decision Support

  NCT03973346

  Condition:   Health Social Determinant
  Intervention:   Other: Risk screening tool exposure
  Sponsors:   Indiana University;   Robert Wood Johnson Foundation
  Enrolling by invitation
• Diabetes Prevention Programming for Women With a History of Gestational Diabetes

  NCT03971838

  Condition:   Diabetes Mellitus, Type 2
  Intervention:   Behavioral: Positive Outcomes for Women
  Sponsor:   Indiana University
  Recruiting
• Trial of Netarsudil for Acceleration of Corneal Endothelial Restoration

  NCT03971357

  Condition:   Fuchs' Endothelial Dystrophy
  Interventions:   Drug: Netarsudil;   Drug: Placebo
  Sponsor:   Price Vision Group
  Recruiting
• Beyond the Lung Cancer Diagnosis: Leveraging the Oncology Clinic Setting for Actively Smoking Family Members

  NCT03966807

  Condition:   Lung Cancer
  Interventions:   Behavioral: Digital-based support;   Behavioral: Traditional-based support + Nicotine replacement therapy (NRT)
  Sponsor:   Indiana University
  Not yet recruiting
• Immunology of HIV and Alcoholic Hepatitis

  NCT03951662

  Conditions:   HIV/AIDS;   Alcoholic Hepatitis
  Interventions:   Other: Alcoholic Hepatitis Group;   Other: Heavy Drinking Controls without Hepatitis
  Sponsor:   Indiana University
  Not yet recruiting
• Are All Snacks Created Equal?

  NCT03940105

  Condition:   Snacking
  Intervention:   Behavioral: Packout
  Sponsors:   Purdue University;   Sabra Dipping Company, LLC
  Completed
• Healthy Weight for Teens

  NCT03939494

  Condition:   Obesity
  Intervention:   Behavioral: Telehealth Encounter
  Sponsors:   Children's Hospital Medical Center, Cincinnati;   Helen DeVos Children's Hospital
  Recruiting
• Development of Adaptive Vacuum Suspension to Improve Prosthetic Fit and Residual Limb Health

  NCT03927404

  Condition:   Lower Limb Amputation
  Intervention:   Device: Active vacuum test prosthesis
  Sponsors:   Indiana University;   United States Department of Defense
  Not yet recruiting
• Effects of Replacing Starchy Vegetables and Refined Grains With Beef on Cardio-metabolic Disease Risk Factors (S53)

  NCT03925142

  Condition:   Diet Modification
  Interventions:   Other: Controlled healthy vegetarian diet;   Other: Controlled beef diet
  Sponsor:   Purdue University
  Recruiting
• Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes

  NCT03923374

  Conditions:   Opioid-use Disorder;   Opioid Use, Unspecified;   Buprenorphine Dependence
  Interventions:   Drug: Subutex / Buprenorphine;   Diagnostic Test: Fetal & Neonatal MRI;   Diagnostic Test: DNA/Genetic/Pharmacokenetic Blood Draws
  Sponsors:   Indiana University;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Institute on Drug Abuse (NIDA)
  Recruiting
• Comparison of Standard vs. Accelerated Corneal Crosslinking

  NCT03922542

  Conditions:   Keratoconus;   Ectasia Corneal
  Interventions:   Combination Product: riboflavin 0.1%;   Combination Product: Riboflavin 0.1%
  Sponsor:   Price Vision Group
  Recruiting
• Open-label Multicenter Phase 1 Study of TBI 302 as Second-Line Therapy in Patients With Hepatocellular Carcinoma

  NCT03908840

  Condition:   Hepatocellular Carcinoma
  Intervention:   Biological: TBI 302
  Sponsor:   Therapure Biopharma Inc
  Not yet recruiting
• Physiological Phenotyping of Respiratory Outcomes in Infants Born Premature

  NCT03906708

  Condition:   Premature Lungs
  Intervention:   Other: Diffusion Capacity of the Lung for Carbon Monoxide (DLCO)
  Sponsors:   Indiana University;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
  Recruiting
• Physiologic Approach to Sodium Supplementation in Premature Infants

  NCT03889197

  Condition:   Postnatal Growth Disorder
  Intervention:   Other: Sodium supplementation algorithm guided by urine sodium concentration
  Sponsors:   Indiana University;   Thrasher Research Fund
  Recruiting
• Integrating an Occupational Therapy Health and Wellness Program Into an Existing Cancer Support Community

  NCT03888547

  Condition:   Cancer
  Intervention:   Other: Occupational Therapy Health & Wellness Education
  Sponsors:   University of Indianapolis;   Indiana Clinical and Translational Sciences Institute
  Recruiting
• Safety and Efficacy of the ToothWave Power Toothbrush for Extrinsic Stain Reduction

  NCT03885609

  Condition:   Tooth Discoloration
  Interventions:   Device: ToothWave;   Device: powered toothbrush
  Sponsor:   Home Skinovations Ltd.
  Completed
• Effects of Consuming Red Meat on the Gut Microbiota in Young Adults

  NCT03885544

  Condition:   Diet Modification
  Interventions:   Other: Controlled Lacto-ovo vegetarian diet;   Other: Controlled Unprocessed red meat diet;   Other: Controlled processed red meat diet
  Sponsor:   Purdue University
  Recruiting
• ToothWave Plaque and Gingivitis Study

  NCT03885323

  Conditions:   Gingivitis;   Plaque;   Calculus, Dental
  Interventions:   Device: RF utilizing powered toothbrush;   Device: Control placebo with no RF
  Sponsor:   Home Skinovations Ltd.
  Completed
• Salivary Interactions With Chemosensations

  NCT03883880

  Condition:   Diet, Food Choice, Taste
  Interventions:   Other: Epigallocatechin gallate;   Other: Epigallocatechin gallate control;   Other: Linoleic acid;   Other: Linoleic acid control;   Other: Capsaicin solution;   Other: Capsaicin control
  Sponsors:   Purdue University;   National Institutes of Health (NIH)
  Recruiting
• On-Eye Optical Quality of Lotrafilcon B Lenses Over 12 Hours

  NCT03881670

  Conditions:   Hyperopia;   Myopia
  Interventions:   Device: Lotrafilcon B;   Device: lotrafilcon B with Hydraluxe
  Sponsors:   Indiana University;   Alcon Research
  Completed
• Non-Invasive Cardiac Output Monitor in Children

  NCT03869606

  Conditions:   Cardiac Output, Low;   Pediatric
  Intervention:   Device: NICOM by Cheetah Medical
  Sponsor:   Indiana University
  Recruiting
• Association Between Lactase Deficiency, and the Small Intestinal Microbiome in Adults.

  NCT03860051

  Condition:   Lactose Intolerance
  Intervention:  
  Sponsor:   Indiana University
  Recruiting
• Erector Spinae Block Versus Surgeon Infiltration in VATS Procedures

  NCT03859635

  Conditions:   Pain, Postoperative;   Thoracic;   Acute Pain
  Interventions:   Procedure: Ultrasound Guided LB Erector Spinae Plane Block;   Procedure: Ultrasound Guided SB Erector Spinae Plane Block;   Procedure: Surgeon Infiltration
  Sponsor:   Indiana University
  Recruiting
• Observation of the Incidence and Natural History of MGUS in Patients Undergoing Weight Reduction Surgery

  NCT03855878

  Condition:   Monoclonal Gammopathy of Undetermined Significance
  Intervention:  
  Sponsor:   Indiana University
  Recruiting
• Testing a Novel Community-based Occupational Therapy Model

  NCT03855761

  Condition:   Mental Disorders, Severe
  Interventions:   Behavioral: Occupational Therapy;   Behavioral: Case management; psychological services
  Sponsors:   Indiana University;   Eskenazi Health
  Recruiting
• Effects of the GOLO Weight Management Program With and Without Release Supplement on Weight and Metabolic Parameters in Subjects With Obesity

  NCT03842501

  Condition:   Obesity
  Interventions:   Dietary Supplement: Release Supplement;   Dietary Supplement: Placebo
  Sponsor:   Golo
  Completed
• A Study Evaluating Safety and Efficacy of Niraparib in Patients With Previously Treated Metastatic Esophageal/Gastroesophageal Junction/Proximal Gastric Adenocarcinoma

  NCT03840967

  Conditions:   Esophageal Cancer;   Gastric Cancer;   Adenocarcinoma
  Intervention:   Drug: Niraparib
  Sponsors:   Shadia Jalal, MD;   Tesaro, Inc.;   Indiana University School of Medicine
  Recruiting
• Reducing the Risk of Drug-Induced QT Interval Lengthening in Women

  NCT03834883

  Conditions:   Long QT Syndrome;   Abnormalities, Drug-Induced
  Interventions:   Drug: Progesterone;   Drug: Ibutilide
  Sponsors:   Indiana University;   American Heart Association;   Purdue University
  Recruiting
• Sex Differences in the Response to Abstinence From Alcohol.

  NCT03827460

  Condition:   Alcohol Use Disorder
  Interventions:   Behavioral: Abstinence from alcohol;   Behavioral: Usual drinking
  Sponsor:   Indiana University
  Recruiting
• Feasibility, Acceptability and Preliminary Effects of the Spiritual Care Assessment and Intervention

  NCT03823313

  Conditions:   Advanced Cancer;   Metastatic Cancer
  Intervention:   Behavioral: SCAI (Spiritual Care Assessment and Intervention)
  Sponsors:   Indiana University;   Indiana University Health
  Recruiting
• Single Shot Liposomal Bupivicaine in Rotator Cuff Surgery

  NCT03822182

  Conditions:   Rotator Cuff Tear;   Pain, Postoperative
  Interventions:   Drug: liposomal bupivicaine;   Drug: Dexamethasone
  Sponsor:   Indiana University
  Recruiting
• Mechanisms of EPO-induced Hypertension

  NCT03810911

  Conditions:   Chronic Kidney Disease;   Blood Pressure;   Anemia
  Intervention:   Drug: Darbepoetin
  Sponsor:   VA Office of Research and Development
  Not yet recruiting
• Testing Utility of Commercially Available Sleep Trackers for Physician-Patient Communication

  NCT03795129

  Condition:   Insomnia
  Interventions:   Behavioral: SleepLife Application w/FitBit;   Behavioral: FitBit w/Minimal to No SleepLife App.
  Sponsors:   Regenstrief Institute, Inc.;   Merck Sharp & Dohme Corp.;   National Sleep Foundation
  Recruiting
• Genetic and Epigenetic Basis of Chronic Wounds

  NCT03793062

  Condition:   Chronic Wounds
  Intervention:   Other: no interventions
  Sponsor:   Chandan Sen
  Recruiting
• Biodynamic Imaging Utility in Predicting Response to Gemcitabine Chemotherapy in Mycosis Fungoides

  NCT03789864

  Conditions:   Lymphoma, T-Cell, Cutaneous;   Mycosis Fungoides
  Intervention:   Diagnostic Test: single-arm, non-randomized Biodynamic imaging (BDI)
  Sponsors:   Indiana University;   Purdue University
  Recruiting
• Canine-Assisted Anxiety Reduction In Emergency Care

  NCT03784573

  Conditions:   Anxiety;   Opioid Use;   Children;   Therapy Dog
  Interventions:   Behavioral: Dog + handler;   Behavioral: No dog
  Sponsor:   Indiana University
  Recruiting
• Indiana Palliative Excellence in Alzheimer's Care Efforts

  NCT03773757

  Condition:   Dementia
  Intervention:   Behavioral: IN-PEACE Dementia Care Coordination
  Sponsors:   Indiana University;   Regenstrief Institute, Inc.
  Recruiting
• Home-based Leg Heat Therapy

  NCT03763331

  Condition:   Peripheral Arterial Disease
  Interventions:   Device: Control/Sham Treatment;   Device: Heat Therapy
  Sponsors:   Indiana University;   Bruno Roseguini, PhD;   Michael Emery, MD
  Recruiting
• Controlled Phonation and Vocal Rest Programs After Acute Vocal Exertion in Healthy Adults

  NCT03762993

  Condition:   Healthy
  Intervention:   Behavioral: Vocal rest and Controlled Phonation
  Sponsor:   Purdue University
  Recruiting
• Effectiveness of Two Different Forms of Marine Oil on Indirect Markers of Muscle Damage and Soreness in Untrained Men

  NCT03760757

  Condition:   Inflammation; Muscle
  Interventions:   Dietary Supplement: ESPO-572®;   Dietary Supplement: PCSO-524®
  Sponsor:   Indiana University
  Recruiting
• Onco4D(TM) Biodynamic Chemotherapy Selection for Bladder Cancer Patients

  NCT03739177

  Condition:   Bladder Cancer
  Intervention:   Diagnostic Test: Onco4D Biodynamic Chemotherapy Selection Assay
  Sponsor:   Animated Dynamics, Inc.
  Recruiting
• Effectiveness of Dry Needling of the Sternocleidomastoid in Patients With Cervicogenic Headaches

  NCT03730896

  Condition:   Cervicogenic Headache
  Intervention:   Procedure: Dry needling
  Sponsor:   Florida Gulf Coast University
  Recruiting
• Spontaneous Regression in Metastatic Melanoma and Renal Cell Carcinoma

  NCT03728842

  Condition:   Melanoma; Renal Cell Carcinoma
  Interventions:   Other: Blood collection for laboratory studies;   Other: Data collection from medical record
  Sponsor:   Indiana University
  Recruiting
• Optimal Time for In-situ Dry Needling to Affect the Autonomic Nervous System

  NCT03728751

  Condition:   Healthy
  Intervention:   Procedure: Dry needling
  Sponsor:   Florida Gulf Coast University
  Completed
• High Intensity Exercise in Incomplete SCI

  NCT03714997

  Condition:   Spinal Cord Injuries
  Intervention:   Procedure: Walking training
  Sponsors:   Indiana University;   Rehabilitation Hospital of Indiana
  Not yet recruiting
• Comparing the Digestion of Milk With Different Beta-casein Protein Content by Dairy Intolerant Persons

  NCT03713346

  Condition:   Dairy Intolerance
  Interventions:   Other: Lactose free milk;   Other: Jersey milk;   Other: High A1 β-casein milk;   Other: High A2 β-casein milk
  Sponsor:   Purdue University
  Recruiting
• A Study to Investigate Food Occlusion Efficacy of a Denture Adhesive in Denture Wearers

  NCT03709810

  Condition:   Denture Retention
  Interventions:   Combination Product: Marketed Denture Adhesive (Super Poligrip Max Seal);   Other: No Adhesive
  Sponsor:   GlaxoSmithKline
  Completed
• Comparing Liposomal Bupivacaine VS Standard Bupivacaine in Colorectal Surgery

  NCT03702621

  Condition:   Colorectal Surgery
  Interventions:   Procedure: Quadratus Lumborum (QL) Block with liposomal Bupivacaine;   Procedure: Quadratus Lumborum (QL) Block with Standard Bupivacaine
  Sponsor:   Indiana University
  Active, not recruiting
• IMRT-TMI With Fludarabine as Myeloablative Conditioning for Allogeneic HSCT

  NCT03696537

  Conditions:   Acute Myeloid Leukemia;   Chronic Myeloid Leukemia;   Acute Lymphatic Leukemia;   Myelodysplastic Syndromes
  Interventions:   Drug: Fludarabine;   Radiation: Total Marrow Irradiation (TMI)
  Sponsors:   Naoyuki G. Saito, M.D., Ph.D.;   Indiana University
  Recruiting
• Study of Imatinib in Children With Neurofibromatosis and Airway Tumors

  NCT03688568

  Condition:   Neurofibroma, Plexiform
  Intervention:   Drug: Imatinib Mesylate
  Sponsors:   Indiana University;   Food and Drug Administration (FDA)
  Recruiting
• Prospective Study for the Treatment of Atherosclerotic Lesions in the Superficial Femoral and/or Popliteal Arteries Using the FLEX Scoring Catheter Plus DCB

  NCT03676842

  Condition:   Peripheral Artery Disease
  Intervention:   Combination Product: FLEX Dynamic Scoring Catheter with IN.PACT Admiral DCB
  Sponsor:   VentureMed Group Inc.
  Recruiting
• Clinical Evaluation of the "NICU Clinical Decision Support Dashboard" - MHSB

  NCT03673579

  Conditions:   Preterm Birth;   Low; Birthweight, Extremely (999 Grams or Less);   Neonatal Infection;   Satisfaction;   Stress;   Chronic Lung Disease;   Growth Acceleration;   Adverse Event
  Intervention:   Device: NICU Dashboard
  Sponsors:   Philips Healthcare;   Memorial Hospital of South Bend
  Recruiting
• Participatory Music Program for Homeless Veterans

  NCT03653130

  Condition:   Quality of Life
  Intervention:   Behavioral: Crossroads Orchestra Participatory Music Program
  Sponsor:   VA Quality Enhancement Research Intiative
  Recruiting
• Melodica Orchestra for Dyspnea: Safety and Feasibility Pilot

  NCT03653104

  Conditions:   COPD;   Chronic Obstructive Pulmonary Disease;   Dyspnea;   Breathlessness;   Emphysema;   Chronic Bronchitis
  Interventions:   Behavioral: Melodica Intervention;   Behavioral: Pulmonary Health Education
  Sponsor:   VA Quality Enhancement Research Intiative
  Recruiting
• Evaluation of the Efficacy of Contrast Enhanced Ultrasound Compared to MRI for Differentiation of Hepatic Lesions

  NCT03652636

  Condition:   Hepatic Disease
  Intervention:   Other: Ultrasound of liver
  Sponsor:   Indiana University
  Recruiting
• Protein Source on Plasma Amino Acid Concentrations

  NCT03649568

  Condition:   Protein Deposition
  Interventions:   Other: Pork;   Other: Egg;   Other: Black beans;   Other: Almonds
  Sponsor:   Purdue University
  Recruiting
• Human Alcohol Seeking Despite Aversion

  NCT03648840

  Condition:   Alcohol Abuse
  Interventions:   Behavioral: Aversive cue;   Behavioral: Neutral cue
  Sponsors:   Indiana University;   Purdue University
  Recruiting
• Intervention to Change Attributions That Are Negative (ICAN)

  NCT03648476

  Conditions:   Trauma, Brain;   Brain Injuries;   Traumatic Brain Injury;   Brain Injuries, Traumatic;   Brain, Trauma
  Intervention:   Behavioral: ICAN
  Sponsors:   Indiana University;   National Institutes of Health (NIH);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
  Recruiting
• A Treatment Protocol for Expanded Access Administration of Prometic Plasminogen Due to Closure of Clinical Trial

  NCT03642691

  Condition:   Hypoplasminogenemia
  Intervention:   Biological: Ryplazim
  Sponsor:   Prometic Biotherapeutics, Inc.
  Available
• Effect of TrueTear Corneal Surface Imaging

  NCT03637348

  Conditions:   Cataract;   Myopia
  Intervention:   Device: TrueTear
  Sponsors:   Price Vision Group;   Allergan
  Completed
• Concurrent Treatment for Patients With Cervical Radiculopathy

  NCT03636009

  Condition:   Spinal Nerve Root Disorder Nos
  Interventions:   Other: concurrent traction and neuromobilization technique;   Other: sequential traction and neuromobilization technique;   Other: active exercise program;   Other: manual therapy to cervical and thoracic spine
  Sponsor:   University of Indianapolis
  Recruiting
• Bladder Catheters During Ablation Procedures

  NCT03635034

  Conditions:   Atrial Fibrillation;   Catheter Ablation;   Catheter Complications
  Interventions:   Device: Insert bladder catheter;   Device: No catheter
  Sponsor:   St. Vincent Cardiovascular Research Institute
  Recruiting
• Digestive Properties of Carbohydrate-based Foods

  NCT03630458

  Conditions:   Obesity;   Diabetes Mellitus, Type 2;   Appetitive Behavior
  Interventions:   Other: Pearl millet couscous - made in Senegal;   Other: Pearl millet couscous - made in USA;   Other: Pearl millet thick porridge;   Other: Wheat couscous;   Other: White rice
  Sponsor:   Purdue University
  Active, not recruiting
• Slowly Digestible Carbohydrates and the Ileal Brake

  NCT03630445

  Conditions:   Obesity;   Diabetes Mellitus, Type 2;   Appetitive Behavior
  Interventions:   Other: Isomaltooligosaccharides (IMOs);   Other: Xtend® sucromalt;   Other: Combination of IMOs and Xtend® sucromalt;   Other: Raw corn starch;   Other: Maltodextrin
  Sponsors:   Purdue University;   General Mills Inc.
  Completed
• Impact of Slowly Digestible Carbohydrates on Gastric Emptying Rates

  NCT03630263

  Conditions:   Obesity;   Diabetes Mellitus, Type 2;   Appetitive Behavior
  Interventions:   Other: Raw Corn Starch;   Other: No Raw Corn Starch
  Sponsor:   Purdue University
  Recruiting
• Intraosseous Basivertebral Nerve Ablation for the Treatment of Chronic Low Back Pain

  NCT03630133

  Condition:   Chronic Low Back Pain
  Intervention:   Device: Intracept System Ablation
  Sponsor:   Relievant Medsystems, Inc.
  Active, not recruiting
• An Evaluation of Tailored Messages to Address Parental Questions About HPV Vaccination

  NCT03628885

  Conditions:   Human Papilloma Virus Vaccines;   Attitude to Health
  Interventions:   Behavioral: Top Concern Tailored Intervention;   Behavioral: All Concerns Tailored Intervention
  Sponsor:   Indiana University
  Completed
• Opioid Use After Traumatic Injury in Adolescents

  NCT03628846

  Conditions:   Opioid Use;   Traumatic Injury;   Adolescent Behavior;   Substance Abuse Disorder
  Intervention:  
  Sponsor:   Indiana University
  Recruiting
• Canine Assisted Therapy to Reduce Emergency Care Provider Stress

  NCT03628820

  Conditions:   Stress;   Anxiety
  Interventions:   Behavioral: Dog Therapy;   Behavioral: Coloring
  Sponsor:   Indiana University
  Enrolling by invitation
• Collection of Specimens and Clinical Data to Create A Bio-repository for Multiple Myeloma

  NCT03616483

  Condition:   Plasma Cell Dyscrasias
  Intervention:   Other: This is a non-interventional trial
  Sponsor:   Indiana University
  Recruiting
• Building Strength Through Rehabilitation for Heart Failure Patients (BISTRO-STUDY)

  NCT03615469

  Condition:   Heart Failure
  Interventions:   Device: Transcutaneous electrical stimulation;   Device: Neuromuscular electrical stimulation
  Sponsors:   Indiana University;   National Heart, Lung, and Blood Institute (NHLBI)
  Recruiting
• Dose-response Effect of Dietary Nitrate on Muscle Function in Older Individuals

  NCT03595774

  Conditions:   Aging;   Sarcopenia
  Intervention:   Dietary Supplement: Beet root juice
  Sponsor:   Indiana University
  Recruiting
• The Benefits of Consuming Hummus as an Afternoon Snack

  NCT03595462

  Condition:   Appetitive Behavior
  Interventions:   Other: Snack;   Other: No Snack
  Sponsor:   Purdue University
  Completed
• The Effects of Protein Source on Appetite Control, Satiety, and Subsequent Food Intake: A Clinical Screening Study

  NCT03595436

  Condition:   Appetitive Behavior
  Interventions:   Dietary Supplement: Pea Protein-20g;   Dietary Supplement: Pea Protein-30g;   Dietary Supplement: Pea Protein-40g;   Dietary Supplement: Whey Protein-20g;   Dietary Supplement: Carbohydrate Control
  Sponsor:   Purdue University
  Completed
• The Impact of Soft Contact Lens Attributes on Symptoms Associated With Digital Eye Strain in Symptomatic Soft Contact Lens Wearers

  NCT03585790

  Conditions:   Asthenopia;   Myopia
  Interventions:   Device: Contact lens with Multifocal Optics;   Device: Contact lens with Single Vision Optics
  Sponsors:   Pete Kollbaum, OD, PhD;   Alcon Research
  Completed
• Prospective Evaluation of the Incidence of PICS

  NCT03584399

  Condition:   Metabolism and Nutrition Disorder
  Intervention:   Other: PICS in critically ill pediatric population
  Sponsors:   Indiana University;   American Society for Parenteral and Enteral Nutrition
  Recruiting
• Effects of Aromatase Inhibitor Therapy on Muscle Function

  NCT03581552

  Conditions:   Breast Cancer;   Breast Cancer Female
  Intervention:  
  Sponsor:   Tarah Ballinger
  Recruiting
• Comparing 3 Different Types of Pain Blocks After Laparoscopic Nephrectomy

  NCT03581539

  Condition:   Nephrectomy
  Interventions:   Procedure: Transverses Abdominis Plane (TAP) block;   Procedure: Quadratus Lumborum (QL) block;   Procedure: Surgeon Infiltration using Exparel
  Sponsor:   Indiana University
  Recruiting
• Radial Forearm Versus the Ulnar Forearm Free Flap

  NCT03579277

  Condition:   Free Tissue Flaps
  Interventions:   Procedure: Radial Forearm Free Flap;   Procedure: Ulnar Forearm Free Flap
  Sponsor:   Indiana University
  Enrolling by invitation
• Determinants of Early Cystic Fibrosis Lung Disease

  NCT03579173

  Condition:   Cystic Fibrosis in Children
  Interventions:   Diagnostic Test: Infant PFT;   Diagnostic Test: Lung Clearance Index;   Diagnostic Test: Passive tidal breathing
  Sponsor:   Indiana University
  Recruiting
• Communication and Activation in Pain to Enhance Relationships and Treat Pain With Equity

  NCT03562793

  Condition:   Pain
  Intervention:   Behavioral: Communication and Activation in Pain to Enhance Relationships and Treat Pain with Equity (COOPERATE)
  Sponsor:   VA Office of Research and Development
  Recruiting
• Endocuff Vision Colonoscopy vs. AmplifEYE Colonoscopy

  NCT03560128

  Conditions:   Colorectal Adenoma;   Colorectal Polyp;   Colorectal Cancer
  Interventions:   Device: Endocuff Vision device;   Device: AmplifEYE device
  Sponsor:   Indiana University
  Completed
• Implementation and Evaluation of SBIRT

  NCT03560076

  Condition:   Substance Use Disorders
  Intervention:   Other: SBIRT Training and Implementation Strategies
  Sponsor:   Indiana University
  Active, not recruiting
• Investigating the Preventative Ability of Massage Therapy on Paclitaxel Induced Peripheral Neuropathy

  NCT03557554

  Conditions:   Breast Cancer;   Neuropathy;   Neuropathy;Peripheral
  Intervention:   Other: Massage
  Sponsors:   Bryan Schneider;   Massage Therapy Foundation
  Recruiting
• The Effects of Postoperative Physician Phone Calls for Hand and Wrist Fractures

  NCT03557073

  Conditions:   Hand Injuries;   Trauma;   Hand Injuries and Disorders
  Intervention:   Behavioral: Postoperative phone call
  Sponsor:   Indiana University
  Completed
• Viewing Surface Electrical Stimulation on Pelvic Floor With Ultrasound

  NCT03528928

  Condition:   Pelvic Floor Disorders
  Intervention:   Device: Surface electrical stimulation
  Sponsor:   Elidah, Inc.
  Active, not recruiting
• Dietary Nitrate and Muscle Power With Aging

  NCT03513302

  Conditions:   Aging;   Sarcopenia
  Interventions:   Dietary Supplement: placebo;   Dietary Supplement: nitrate
  Sponsor:   Indiana University
  Recruiting
• Improving Patient Communication About SUDEP

  NCT03502759

  Conditions:   SUDEP;   Epilepsy
  Intervention:   Behavioral: CHICA SUDEP module
  Sponsors:   Indiana University;   Child Neurology Foundation;   Greenwich Biosciences
  Recruiting
• Interaction of Salivary Proteins and Polyphenols

  NCT03501238

  Conditions:   Diet Habit;   Diet Modification;   Taste, Altered;   Saliva Altered
  Interventions:   Other: Chocolate Milk;   Other: Chocolate milk substitute;   Other: Chocolate milk substitute with gelatin
  Sponsor:   Purdue University
  Completed
• PG and PK of Oxycodone to Personalize Post-op Pain Management Following Surgery in Children

  NCT03495388

  Conditions:   Postoperative Pain;   Opioid Dependence
  Intervention:  
  Sponsors:   Indiana University;   Children's Hospital Medical Center, Cincinnati;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
  Recruiting
• Pilot Study of Taste Sensations in Patients With End-stage Renal Disease on Hemodialysis

  NCT03495271

  Condition:   End Stage Renal Disease
  Intervention:  
  Sponsor:   Purdue University
  Completed
• Effects of Soccer Heading on Ocular-motor Function and Blood Biomarker

  NCT03488381

  Condition:   Trauma, Head
  Intervention:   Device: Soccer Heading
  Sponsor:   Indiana University
  Completed
• Diabetic Foot Ulcer Recurrence: Pilot Study

  NCT03479242

  Conditions:   Diabetic Foot;   Ulcer Foot
  Intervention:   Other: no interventions
  Sponsors:   Indiana University;   Stanford University
  Recruiting
• Oral and Dermal Tolerability Clinical Study of an Experimental Denture Wipe

  NCT03478644

  Condition:   Denture Cleansers
  Interventions:   Device: Experimental Denture Wipe;   Other: Tap Water
  Sponsor:   GlaxoSmithKline
  Completed
• GOLO Open-Label Pilot 1

  NCT03478202

  Condition:   Diabetes Mellitus, Type II
  Intervention:   Dietary Supplement: GOLO RELEASE
  Sponsor:   Golo
  Completed
• Canine-assisted ANxiety Reduction IN Emergency

  NCT03471429

  Condition:   Anxiety
  Intervention:  
  Sponsor:   Indiana University
  Completed
• Whole Grains, Gastric Emptying and Glycemic Response

  NCT03467659

  Conditions:   Obesity;   Diabetes Mellitus, Type 2;   Appetitive Behavior
  Interventions:   Other: Cracked whole wheat porridge;   Other: Semolina wheat porridge;   Other: Whole wheat flour porridge;   Other: Refined wheat flour porridge;   Other: Refined wheat flour porridge,fine bran;   Other: Refined wheat flour porridge,coarse bran
  Sponsor:   Purdue University
  Completed
• Quad Resection (Hot Snare vs Cold Snare vs Hot EMR vs Cold EMR)

  NCT03462706

  Conditions:   Colon Cancer;   Colon Polyp;   Colon Adenoma
  Interventions:   Procedure: Cold Snare;   Procedure: Hot Snare;   Procedure: Cold EMR;   Procedure: Hot EMR
  Sponsor:   Indiana University
  Recruiting
• Reactions to E-cigs and Alcohol

  NCT03449017

  Conditions:   Alcohol Abuse;   Nicotine Dependence Tobacco Product
  Intervention:   Behavioral: E-cig use
  Sponsors:   Indiana University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
  Completed
• Infant Behavioral Sleep Intervention: Comparative Efficacy

  NCT03447665

  Condition:   Insomnia
  Interventions:   Behavioral: Bedtime routine;   Behavioral: Sleep schedule;   Behavioral: Intervention (bedtime);   Behavioral: Intervention (after night wakings)
  Sponsors:   Indiana University;   Purdue University;   Saint-Joseph University
  Completed
• Biodistribution and Dosimetry of Ga-68 P16-093 in Prostate Cancer With Biochemical Recurrence

  NCT03444844

  Conditions:   Prostate Cancer Recurrent;   Prostate Cancer
  Intervention:   Drug: Ga-68 P16-093 PET/CT scan
  Sponsors:   Five Eleven Pharma, Inc.;   Indiana University
  Recruiting
• Pathogenetic Basis of Aortopathy and Aortic Valve Disease

  NCT03440697

  Conditions:   Aortopathies;   Thoracic Aortic Aneurysm;   Aortic Valve Disease;   Thoracic Aortic Disease;   Thoracic Aortic Dissection;   Thoracic Aortic Rupture;   Ascending Aortic Disease;   Descending Aortic Disease;   Ascending Aortic Aneurysm;   Descending Aortic Aneurysm;   Marfan Syndrome;   Loeys-Dietz Syndrome;   Ehlers-Danlos Syndrome;   Shprintzen-Goldberg Syndrome;   Turner Syndrome;   PHACE Syndrome;   Autosomal Recessive Cutis Laxa;   Congenital Contractural Arachnodactyly;   Arterial Tortuosity Syndrome
  Intervention:  
  Sponsor:   Indiana University
  Recruiting
• Improving Functional Ability in Chronic TBI With Intensive Rehabilitation Robotic Gait Training

  NCT03438409

  Condition:   TBI (Traumatic Brain Injury)
  Intervention:   Other: Robotic gait training
  Sponsor:   Indiana University
  Terminated
• The Indiana SNAP-Ed Long-term Study Sequel

  NCT03436784

  Condition:   Nutrient Intake Inadequacy
  Intervention:   Behavioral: Indiana SNAP-Ed
  Sponsors:   Purdue University;   Purdue University Cooperative Extension Nutrition Education Program;   Purdue University AgSEED
  Completed
• The Indiana SNAP-Ed Long-term Study

  NCT03436589

  Conditions:   Food Insecurity;   Food Security;   Education
  Intervention:   Behavioral: Indiana SNAP-Ed
  Sponsors:   Purdue University;   University of Kentucky Center for Poverty Research;   Purdue University Cooperative Extension Family Nutrition Program;   North Central Nutrition Education Center of Excellence
  Completed
• Heat Therapy to Reduce Pain and Improve Walking Tolerance

  NCT03435835

  Condition:   Peripheral Arterial Disease
  Interventions:   Device: Control/Sham Treatment;   Device: Heat Therapy (HT)
  Sponsors:   Indiana University;   Bruno Roseguini, PhD;   Michael Emery, MD
  Enrolling by invitation
• Evaluation of an Exercise Intervention for Vincristine Induced Peripheral Neuropathy in Pediatric Cancer Patients

  NCT03430674

  Condition:   Peripheral Neuropathy
  Intervention:   Behavioral: Exercise
  Sponsor:   Indiana University
  Recruiting
• Comparing Surgical and Economical Parameters of Total Knee Replacement.

  NCT03427047

  Conditions:   Osteo Arthritis Knee;   Total Knee Arthroplasty
  Interventions:   Device: MyKnee with single use Efficiency Instrument;   Device: Stryker Navigational with conventional metal instruments
  Sponsor:   Medacta USA
  Recruiting
• Bupropion Stereoselective Disposition and CYP2D6-mediated Drug Interactions in Healthy Volunteers

  NCT03420469

  Condition:   Adverse Effect of Drug Therapy Metabolism Medications (Diagnosis)
  Intervention:   Drug: Bupropion
  Sponsors:   Indiana University;   National Institute of General Medical Sciences (NIGMS)
  Recruiting
• MINDSpeed Food and Brain Training RCT

  NCT03419052

  Condition:   Low Education
  Intervention:   Behavioral: Speed of processing
  Sponsors:   Indiana University;   National Institutes of Health (NIH)
  Recruiting
• EndoRings Colonoscopy vs Standard Colonoscopy

  NCT03418662

  Conditions:   Colorectal Adenoma;   Colorectal Polyp;   Colon Cancer
  Intervention:   Device: EndoRings device
  Sponsors:   Indiana University;   US Endoscopy
  Completed
• Training to Reconnect With Emotional Awareness Therapy

  NCT03414463

  Conditions:   Traumatic Brain Injury;   Alexithymia
  Intervention:   Behavioral: TREAT
  Sponsor:   Indiana University
  Recruiting
• Mediterranean Style Diet and Low Glycemic Responses

  NCT03410719

  Condition:   Insulin Sensitivity
  Intervention:   Other: Hi GI
  Sponsors:   Purdue University;   Federico II University;   University of Agriculture Science, Uppsala, Sweden
  Recruiting
• Effects of Grape Juice With Breakfast on Glycemia and Cognitive Function in Healthy Adults

  NCT03409497

  Conditions:   Glycemic Response;   Appetitive Behavior
  Interventions:   Other: Concord Grape Juice;   Other: Low flavonoid low essence beverage;   Other: Low flavonoid beverage
  Sponsors:   Purdue University;   Welch's Food Corporation
  Not yet recruiting
• Effects of Concord Grape Juice Alone on Glycemia, Appetite and Cognitive Function in Healthy Adults

  NCT03409484

  Conditions:   Glycemic Response;   Appetitive Behavior
  Interventions:   Other: Concord Grape Juice;   Other: Low flavoniod low essence beverage;   Other: Low flavonoid beverage
  Sponsors:   Purdue University;   Welch's Food Corporation
  Active, not recruiting
• The Aging Brain ANSWERS Program

  NCT03397667

  Conditions:   Traumatic Brain Injury;   Alzheimer Disease;   Veterans;   Family Caregivers;   Caregiver Burden;   Quality of Life
  Interventions:   Other: ABC ANSWERS;   Other: Control
  Sponsors:   Indiana University;   Richard L. Roudebush VA Medical Center;   Cleveland State University
  Recruiting
• Cognitive Behavioral Therapy to Treat Insomnia in Persons With HIV Infection

  NCT03390114

  Conditions:   HIV/AIDS;   Insomnia
  Intervention:   Behavioral: SHUTi
  Sponsor:   Indiana University
  Active, not recruiting
• Comparison of Smoflipid to Soy-based Lipid Reduction for Cholestasis Prevention in Surgical Neonates

  NCT03387579

  Condition:   Cholestasis of Parenteral Nutrition
  Interventions:   Drug: Lipid Emulsions, Intravenous;   Drug: Intralipid, 20% Intravenous Emulsion
  Sponsor:   Indiana University
  Recruiting
• Evaluation of the Fluoride Dose Response of a Modified In Situ Caries Model

  NCT03383783

  Condition:   Caries
  Interventions:   Drug: 0 ppm F (placebo, negative control);   Drug: 250 ppm F as NaF (dose-response control);   Drug: 500 ppm F as NaF (dose-response control);   Drug: 1100 ppm F as NaF (positive control)
  Sponsors:   Domenick Zero;   GlaxoSmithKline
  Completed
• Mindfulness-Based Stress Reduction for Adults With Low-Risk Chest Pain Associated With Anxiety

  NCT03365375

  Conditions:   Chest Pain;   Anxiety;   Mindfulness
  Interventions:   Behavioral: MBSR Referral;   Other: Usual Care Referral
  Sponsors:   Indiana University;   Indiana University Health
  Recruiting
• Study of Mind-Body Skills Groups for Adolescents With Depression in Primary Care

  NCT03363750

  Conditions:   Depression;   Depressive Disorder
  Intervention:   Behavioral: mind-body-skills group
  Sponsors:   Indiana University;   The Center for Mind-Body Medicine;   Eskenazi Health
  Recruiting
• Standard Colonoscopy Versus Colonoscopy With Endocuff Vision

  NCT03361917

  Conditions:   Colorectal Polyp;   Colorectal Adenoma;   Colon Cancer
  Intervention:   Device: Endocuff Vision
  Sponsor:   Indiana University
  Completed
• Comparison of New Contact Lens With Current Marketed Lens

  NCT03360110

  Condition:   Myopia
  Interventions:   Device: Phoebe test lens;   Device: stenfilcon A lens (control)
  Sponsor:   Coopervision, Inc.
  Completed
• Evaluation of Glycerin Suppositories to Improve Bowel Function in Gastroschisis

  NCT03355326

  Condition:   Gastroschisis
  Intervention:   Drug: Glycerin Suppository
  Sponsor:   Indiana University
  Recruiting
• A Comparison of Eleview Versus Hetastarch as Injectate for EMR

  NCT03350217

  Conditions:   Procedural Bleeding;   Delayed Bleeding;   Post-Polypectomy Syndrome;   Post Procedural Complication
  Interventions:   Drug: Eleview;   Drug: Hetastarch
  Sponsor:   Indiana University
  Completed
• A Study to Investigate a Method to Measure Food Occlusion by Denture Adhesives in Denture Wearers

  NCT03345108

  Condition:   Denture Retention
  Interventions:   Device: Denture Adhesive Cream (Conventional Application);   Device: Denture Adhesive (Continuous Strip Application);   Other: No Adhesive
  Sponsor:   GlaxoSmithKline
  Completed
• A Pilot Study to Assess Theragnostically Planned Liver Radiation With Functional DVH Analysis to Optimize Individualized Radiation Therapy

  NCT03338062

  Conditions:   Liver Cancer;   Hepatocellular Carcinoma;   Cholangiocarcinoma
  Interventions:   Diagnostic Test: Hepatobiliary Iminodiacetic Acid (HIDA) scan;   Diagnostic Test: MRI with Eovist contrast
  Sponsor:   Indiana University
  Recruiting
• Changes in Esophageal Distensibility With Proton Pump Inhibitors in Patients With Esophageal Eosinophilia: A Pilot Study

  NCT03312686

  Condition:   Eosinophilic Esophagitis
  Intervention:   Diagnostic Test: endoflip
  Sponsor:   Indiana University
  Recruiting
• Factors Predicting Success in Lung Transplant Recipients Who Have Undergone Intensive Post-operative Rehabilitation

  NCT03299504

  Condition:   Lung Transplant
  Intervention:   Other: Exercise
  Sponsor:   Indiana University Health Methodist Hospital
  Completed
• Analysis of Stannous Fluoride in GCF and Subgingival Plaque

  NCT03296657

  Conditions:   Subgingival Plaque;   GCF
  Intervention:   Drug: stannous fluoride
  Sponsor:   Procter and Gamble
  Completed
• In Situ Erosion Study to Investigate the Effectiveness of an Experimental Toothpaste

  NCT03296072

  Condition:   Tooth Erosion
  Interventions:   Drug: 0.254% w/w sodium fluoride and 5% KNO3;   Drug: 0.454% w/w stannous fluoride;   Drug: 5% KNO3
  Sponsor:   GlaxoSmithKline
  Completed
• Biofilm Modified Macrophage Phenotype and Function in Diabetic Wound Healing

  NCT03271580

  Conditions:   Wound;   Bacterial Infections;   Diabetes Mellitus;   Infected Ulcer of Skin
  Interventions:   Diagnostic Test: Finger prick test for HbA1c measurement;   Procedure: Punch Biopsy;   Other: Vac Sponge Collection;   Other: Ankle Brachial Index
  Sponsor:   Sashwati Roy
  Recruiting
• A Study to Investigate the Stain and Plaque Removal Capability of Two Experimental Potassium Nitrate Dentifrices

  NCT03267511

  Condition:   Oral Hygiene
  Interventions:   Drug: 5% KNO3 / 0.2542% NaF dentifrice with 0.5% spherical silica;   Drug: 5% KNO3 / 0.2542% NaF dentifrice with 1% spherical silica and 5% STP;   Drug: 5% KNO3 / 0.2542% NaF dentifrice with 6% abrasive silica;   Drug: 5% KNO3 / 0.2543% NaF dentifrice with 16% abrasive silica and 5% STP
  Sponsor:   GlaxoSmithKline
  Completed
• Intraductal Secretin Stimulation Test: What Is the Proper Collection Time?

  NCT03263481

  Condition:   Cholangiopancreatography, Endoscopic Retrograde
  Intervention:   Drug: Human Secretin for injection 16 mcg
  Sponsor:   Indiana University
  Recruiting
• Mindfulness to Enhance Quality of Life and Support Advance Care Planning

  NCT03257007

  Conditions:   Mindfulness;   Meditation;   Metastatic Cancer;   Quality of Life;   Advance Care Planning;   Palliative Care;   Family Caregiver;   Supportive Care
  Intervention:   Behavioral: Mindfulness
  Sponsor:   Indiana University
  Completed
• Trial of Netarsudil for Prevention of Corticosteroid-induced Intraocular Pressure Elevation

  NCT03248037

  Conditions:   Fuchs' Endothelial Dystrophy;   Bullous Keratopathy
  Interventions:   Drug: Netarsudil;   Drug: Placebo
  Sponsor:   Cornea Research Foundation of America
  Completed
• Reducing Sedentary Time in Fibromyalgia Patients

  NCT03247348

  Conditions:   Fibromyalgia;   Veterans
  Intervention:   Behavioral: ReSeT-FM intervention
  Sponsors:   Indiana University;   Richard L. Roudebush VA Medical Center
  Recruiting
• Quantifying the Efficacy and Role of Service Dogs for Military Veterans With PTSD

  NCT03245814

  Condition:   Post Traumatic Stress Disorder
  Intervention:   Behavioral: Service Dog
  Sponsors:   Marguerite O'Haire;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   National Center for Complementary and Integrative Health (NCCIH)
  Enrolling by invitation
• An Initial Safety Study of Gedatolisib Plus PTK7-ADC for Metastatic Triple-negative Breast Cancer

  NCT03243331

  Conditions:   Triple Negative Breast Cancer;   Metastatic Breast Cancer
  Interventions:   Drug: Gedatolisib;   Drug: PTK7-ADC
  Sponsor:   Kathy Miller
  Recruiting
• A Study to Assess Efficacy of an Experimental Oral Rinse in Providing Long Term Relief From Dentinal Hypersensitivity

  NCT03238352

  Condition:   Dentin Sensitivity
  Interventions:   Device: Potassium oxalate;   Drug: Sodium fluoride;   Other: Placebo
  Sponsor:   GlaxoSmithKline
  Completed
• A Trial Comparing the Incidence of Hypophosphatemia in Relation to Treatment With Iron Isomaltoside and Ferric Carboxymaltose in Subjects With Iron Deficiency Anaemia (IDA-05)

  NCT03237065

  Condition:   IDA - Iron Deficiency Anemia
  Interventions:   Drug: Iron Isomaltoside (Monofer);   Drug: Ferric carboxymaltose
  Sponsor:   Pharmacosmos A/S
  Completed
• Ridge Preservation With Moldable Beta-tricalcium Phosphate Bone Substitute on Non-containable Non-Molar Extraction Sites

  NCT03215667

  Conditions:   Alveolar Ridge Preservation;   Dental Implants
  Intervention:   Device: easy-graft CLASSIC (beta-Tricalcium Phosphate)
  Sponsor:   Sunstar Americas
  Recruiting
• Assessment of a New "Boosting" Strategy for HIV Pre-exposure Prophylaxis in Healthy Volunteers

  NCT03202511

  Condition:   Pre-Exposure Prophylaxis
  Interventions:   Drug: Probenecid Oral Tablet;   Drug: Tenofovir disoproxil fumarate/Emtricitabine
  Sponsor:   Indiana University
  Completed
• Effect of an H1 Receptor Antagonist on Exercise Performance in Hypoxia

  NCT03192488

  Condition:   Exercise Intolerance at Altitude
  Interventions:   Drug: Cetirizine;   Drug: Placebo oral capsule
  Sponsor:   Indiana University
  Unknown status
• Impact of Protein Quantity Within the USDA Healthy Style Eating Pattern on Sleep

  NCT03174769

  Conditions:   Sleep;   Body Composition
  Interventions:   Other: Normal protein;   Other: High protien
  Sponsor:   Purdue University
  Active, not recruiting
• Astringency and Bitterness Perception

  NCT03171402

  Condition:   Taste Bitter-Salty
  Intervention:   Diagnostic Test: Astringency and bitterness perception
  Sponsor:   Purdue University
  Completed
• Bexagliflozin Drug/Drug Interaction Study With Exenatide Injection

  NCT03167411

  Condition:   Type2 Diabetes Mellitus
  Interventions:   Drug: Bexagliflozin;   Drug: Exenatide Injection
  Sponsor:   Theracos
  Completed
• Migraine Prevention Using ActiPatch

  NCT03166046

  Condition:   Migraine
  Interventions:   Device: Pulsed Shortwave Therapy;   Device: Placebo Pulsed Shortwave therapy
  Sponsor:   BioElectronics Corporation
  Completed
• Onco4D(TM) Biodynamic Chemotherapy Selection for Breast Cancer Patients

  NCT03164863

  Condition:   Breast Cancer
  Intervention:   Diagnostic Test: Onco4D Biodynamic Chemotherapy Selection Assay
  Sponsor:   Animated Dynamics, Inc.
  Recruiting
• The Effects of Protein Source on Appetite Control, Satiety, and Subsequent Food Intake

  NCT03154606

  Condition:   Appetitive Behavior
  Interventions:   Other: Micellar Casein (#1);   Other: Micellar Casein (#2);   Other: Calcium Caseinate;   Other: Sodium Caseinate;   Other: Milk Protein Isolate;   Other: Pure Protein Blend;   Other: Whey Protein Isolate;   Other: Native Whey Protein Isolate;   Other: Soy Protein;   Other: Pea Protein;   Other: Native Whey: Micellar Casein (50:50) blend;   Other: Carbohydrate Control
  Sponsor:   Purdue University
  Completed
• Comparison of Three Different Pain Blocks for Subjects Undergoing VATS (Video Assisted Thoracoscopic Surgery) Procedure.

  NCT03151434

  Conditions:   Video Assisted Thoracoscopic Surgery;   Pain, Postoperative;   Pain, Acute
  Interventions:   Procedure: US Guided Single Shot Paravertebral Block;   Procedure: US Guided Paravertebral Catheter;   Procedure: Thoracic Epidural
  Sponsor:   Indiana University
  Recruiting
• Increased Protein at Breakfast for Weight Management in Overweight Adolescents

  NCT03146442

  Condition:   Obesity, Adolescent
  Intervention:   Behavioral: Breakfast
  Sponsors:   Purdue University;   University of Kansas Medical Center;   University of Tennessee;   Banner Alzheimer's Institute
  Recruiting
• Task-specificity for Locomotor Recovery Following SCI

  NCT03144388

  Condition:   Spinal Cord Injuries
  Interventions:   Procedure: Variable Stepping Training;   Procedure: Variable Non-specific Training
  Sponsor:   Indiana University
  Recruiting
• High Protein Breakfast on Weight Management and Glycemic Control in 'Breakfast-skipping' Teens

  NCT03134014

  Conditions:   Breakfast;   Appetitive Behavior
  Intervention:   Dietary Supplement: Breakfast
  Sponsor:   Purdue University
  Completed
• Developing SUPPORT, a Community-Driven, Recovery-Oriented System of Care

  NCT03132753

  Condition:   Substance Use
  Intervention:   Behavioral: SUPPORT
  Sponsor:   Indiana University
  Active, not recruiting
• Sinusoidal Obstruction Syndrome for Stem Cell Transplant Patients Biomarker Study

  NCT03132337

  Condition:   Sinusoidal Obstruction Syndrome
  Intervention:   Other: Serial Blood Draws
  Sponsor:   Indiana University
  Recruiting
• Acute Kidney Injury in Patients Undergoing Contrast Exposure: VQ vs. CT

  NCT03116139

  Conditions:   Acute Kidney Injury;   Pulmonary Embolism;   Contrast-induced Nephropathy
  Interventions:   Diagnostic Test: V/Q imaging;   Diagnostic Test: Computed tomography scan
  Sponsors:   Indiana University;   National Heart, Lung, and Blood Institute (NHLBI)
  Recruiting
• Phosphorus Absorption in Healthy Adults and in Patients With Moderate Chronic Kidney Disease

  NCT03108222

  Condition:   Chronic Kidney Disease Mineral and Bone Disorder
  Intervention:   Other: Phosphorus Absorption Test
  Sponsor:   Purdue University
  Active, not recruiting
• Trial Outcomes for Massage: Caregiver-Assisted vs. Therapist-Treated

  NCT03100539

  Conditions:   Neck Pain;   Chronic Pain;   Pain;   Arthritis;   Musculoskeletal Pain;   Osteoarthritis
  Interventions:   Other: Care giver treatment;   Other: Therapist treated massage
  Sponsor:   VA Office of Research and Development
  Recruiting
• Urine Trypsinogen 2 Dipstick for the Early Detection of Post-ERCP Pancreatitis

  NCT03098082

  Condition:   Post-ERCP Acute Pancreatitis
  Intervention:   Device: Actim Pancreatitis
  Sponsor:   Indiana University
  Recruiting
• Amnion-Chorion Allograft Barrier Used for Root Surface and Guided Tissue Regeneration for Periodontal Intrabony Defects and Grade II Furcation Defects.

  NCT03095976

  Condition:   Periodontal Diseases
  Intervention:   Procedure: Amnion-Chorion allograft membrane on the root surface of periodontally diseased site.
  Sponsor:   Indiana University
  Recruiting
• Translating 3-Step Workout for Life in a Local Senior Living Community

  NCT03095534

  Conditions:   Frail Elderly;   Muscle Weakness
  Intervention:   Behavioral: 3-Step Workout for Life
  Sponsor:   Indiana University
  Completed
• Decreasing Delirium Through Music

  NCT03095443

  Condition:   Delirium
  Interventions:   Other: Music Therapy - Personalized Playlist;   Other: Music Therapy - Standard Playlist;   Other: Attention Control
  Sponsors:   Indiana University;   Regenstrief Institute, Inc.
  Completed
• Patient-Centered Decision Support to Improve Diabetes Management in Pre-Teens and Adolescents With Type 1 Diabetes

  NCT03084900

  Condition:   Diabetes Mellitus
  Intervention:   Other: Arm 1
  Sponsors:   Indiana University;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  Recruiting
• Examining the Effects of Processed Music on Chronic Pain

  NCT03083977

  Condition:   Pain
  Intervention:   Other: Safe and Sound Protocol
  Sponsor:   Indiana University
  Recruiting
• Addressing Place and People Micro Environments in Weight Loss Disparities

  NCT03083964

  Condition:   Obese
  Interventions:   Behavioral: Usual Care;   Behavioral: Priming
  Sponsor:   Indiana University
  Recruiting
• The Efficacy of the AIRVO Warm Humidifier as an Add on to Oxygen Therapy

  NCT03081650

  Conditions:   COPD;   Chronic Obstructive Pulmonary Disease
  Intervention:   Device: Airvo Humidifier
  Sponsors:   Lutheran Hospital, Indiana;   Fisher and Paykel Healthcare
  Unknown status
• Late Function After Surgery for Transposition of the Great Arteries

  NCT03078413

  Condition:   Transposition of Great Vessels
  Intervention:  
  Sponsor:   Indiana University
  Completed
• Assessing Outcomes in ED Patients With RV Failure

  NCT03073629

  Condition:   Right Heart Failure
  Intervention:   Diagnostic Test: Clinical Pathway
  Sponsor:   Indiana University
  Recruiting
• The Acute Effect of Egg-Based High Protein Meal on Hypertensive Response to Exercise

  NCT03073252

  Conditions:   Blood Pressure;   Cardiovascular Risk Factor
  Interventions:   Other: Normal Protein;   Other: HIgh Protein
  Sponsor:   Purdue University
  Completed
• The Effects of LycoRed Phytonutrient and Vitamin Supplement (a.k.a. LYC-001e) on Ocular Blood Flow

  NCT03068377

  Condition:   Ocular Blood Flow
  Interventions:   Dietary Supplement: Experimental;   Dietary Supplement: Placebo
  Sponsors:   LycoRed Ltd.;   Indiana University School of Medicine
  Completed
• Post-prandial Glucose Response From Phytochemical Rich Potato Products

  NCT03066713

  Conditions:   Glycemic Response;   Appetitive Behavior
  Interventions:   Other: Skin Off French Fry;   Other: Skin On French Fry;   Other: Hash brown;   Other: Carbohydrate control
  Sponsors:   Purdue University;   USDA Beltsville Human Nutrition Research Center
  Completed
• Mobile Enhancement of Motivation in Schizophrenia

  NCT03059771

  Conditions:   Schizophrenia;   Schizo Affective Disorder;   Psychosis
  Interventions:   Behavioral: Mobile Enhancement of Motivation (MEMS);   Behavioral: Control
  Sponsors:   Indiana University;   Indiana Clinical and Translational Sciences Institute;   American Psychological Foundation;   Indiana University-Purdue University Indianapolis Department of Psychology
  Completed
• CC100: Phase 1 Multiple-Dose Safety and Tolerability in Subjects With ALS

  NCT03049046

  Condition:   Amyotrophic Lateral Sclerosis
  Interventions:   Drug: CC100;   Drug: Placebos
  Sponsor:   Chemigen, LLC
  Unknown status
• Scheduled Awakenings for the Treatment of Nocturnal Enuresis

  NCT03047720

  Condition:   Nocturnal Enuresis
  Interventions:   Other: One;   Other: Two
  Sponsor:   Indiana University
  Recruiting
• Prospective Analysis of Value of Contrast-enhanced Sonography During Biopsies of Focal Liver Masses

  NCT03040323

  Condition:   Liver Biopsy
  Interventions:   Drug: Lumason 60.7Mg Powder for Injection;   Drug: Placebos
  Sponsor:   Indiana University
  Terminated
• A Clinical Bite Force Study of Two Marketed Adhesives Against no Adhesive

  NCT03037307

  Condition:   Denture Retention
  Interventions:   Other: Test Product;   Other: Positive Contol;   Other: Negative Control
  Sponsor:   GlaxoSmithKline
  Completed
• Evaluation of an Incontinence Product

  NCT03023072

  Condition:   Incontinence
  Intervention:   Other: Incontinence Detection System
  Sponsor:   Hill-Rom
  Terminated
• Nerve Blocks vs Local Injections for Post-op Pain Prevention in Laparoscopic Cholecystectomy in Children

  NCT03022279

  Condition:   Laparoscopic Cholecystectomy
  Interventions:   Procedure: TAP Blocks;   Procedure: local wound infiltration;   Drug: 0.2% ropivacaine;   Device: ultrasound
  Sponsor:   Brian Wallace Gray
  Enrolling by invitation
• Use of Electronic Personal Health Records to Improve Medication Adherence

  NCT03018197

  Conditions:   Atrial Fibrillation;   Medication Adherence
  Intervention:   Other: Medication Education
  Sponsors:   Parkview Health;   Centers for Medicare and Medicaid Services
  Completed
• The Effects of Aspartame on Appetite, Body Composition and Oral Glucose Tolerance

  NCT02999321

  Condition:   Oral Glucose Tolerance
  Interventions:   Other: aspartame;   Other: water
  Sponsors:   Purdue University;   Ajinomoto USA, INC.
  Completed
• Electronic Patient Notification of Remote ICD Data: Impact of Patient Engagement on Outcomes in the Merlin.Net™

  NCT02989090

  Conditions:   Implantable Cardioverter-Defibrillator;   Health Information Exchange;   Electronic Health Records;   Patient Participation
  Interventions:   Other: Receive Detailed ICD Information-electronic;   Other: Receive Detailed ICD Information-paper
  Sponsors:   Parkview Hospital, Indiana;   Abbott Medical Devices
  Completed
• Orthodontic Archwire Comparison Trial

  NCT02983084

  Condition:   Malocclusion
  Intervention:   Device: Orthodontic archwire
  Sponsors:   Ormco Corporation;   Indiana University
  Active, not recruiting
• Fecal Metabolome and the Intestinal Microbiota in Irritable Bowel Syndrome

  NCT02981888

  Condition:   IBS
  Intervention:   Radiation: X-Ray
  Sponsor:   Indiana University
  Recruiting
• A Study to Assess the Effect of Y-90 Therapy on Non-target/Background Liver

  NCT02966223

  Conditions:   HCC;   Liver Cancer
  Intervention:   Radiation: MRI and HIDA scan
  Sponsors:   Indiana University;   BTG International Inc.
  Recruiting
• A Phase1 Study to Explore the Safety of EOS789 in Patients With Chronic Kidney Disease and Hyperphosphatemia on Hemodialysis

  NCT02965053

  Condition:   Hyperphosphatemia
  Interventions:   Drug: EOS789;   Drug: Placebo;   Drug: Renvela
  Sponsor:   Chugai Pharmaceutical
  Completed