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• Evaluation of Pain Alleviating Strategies During Allergy Shots

  NCT04181632

  Conditions:   Immunotherapy;   Allergy
  Interventions:   Device: Buzzy Bee with Ice pack;   Device: Buzzy Bee without Ice pack;   Device: Shot Blocker
  Sponsor:   Nemours Children's Clinic
  Recruiting
• Remote Microphone (RM) - A Comparative Study

  NCT04147611

  Condition:   Hearing Loss, Conductive
  Interventions:   Device: BAHA;   Device: Wireless Audio Streaming Accessory;   Device: Digital Adaptive RM System
  Sponsors:   University of Miami;   Cochlear
  Recruiting
• Rescue of Infants With Mct8 Deficiency

  NCT04143295

  Condition:   Mct8 (Slc16A2)-Specific Thyroid Hormone Cell Transporter Deficiency
  Intervention:   Drug: Diiodothyropropionic acid
  Sponsor:   Roy E. Weiss, M.D.
  Available
• Routine Versus no Assessment of Gastric Residual Volumes in Preterm Infants

  NCT04062851

  Conditions:   Gastric Residual Volume;   Preterm Infant;   Feeding Disorder Neonatal
  Intervention:   Other: No Gastric residual volume monitoring
  Sponsor:   Florida Hospital
  Recruiting
• Evaluation of the Spark of Duval Intervention

  NCT04044027

  Condition:   Teen Pregnancy Prevention
  Intervention:   Behavioral: S.P.A.R.K (Speaking to the Potential, Ability and Resilience inside Kids) Teen Pregnancy Prevention and Mentoring
  Sponsor:   University of South Florida
  Recruiting
• Addition of Acetaminophen in Standard PDA Management

  NCT04026464

  Condition:   Patent Ductus Arteriosus
  Interventions:   Drug: Intravenous Ibuprofen;   Drug: Intravenous Ibuprofen + Oral Acetaminophen
  Sponsor:   University of Florida
  Not yet recruiting
• Skeletal Muscle Effects of GH in Boys

  NCT04020913

  Conditions:   Growth Hormone Deficiency;   Idiopathic Short Stature
  Intervention:   Drug: Somatropin injection
  Sponsors:   Nemours Children's Clinic;   Novo Nordisk A/S
  Recruiting
• MCRF Clinical Pilot Study

  NCT03991585

  Condition:   Emotional Adjustment
  Intervention:   Behavioral: Musical Contour Regulation Facilitation (MCRF)
  Sponsors:   University of Miami;   American Music Therapy Association;   University of Kansas
  Active, not recruiting
• Reducing Obesity Health Disparities in Hispanic Youth

  NCT03943628

  Conditions:   Overweight;   Family Relations;   Adolescent Behavior;   Drug Use;   Sexual Behavior
  Intervention:   Behavioral: Familias Unidas
  Sponsors:   University of Miami;   National Institutes of Health (NIH);   National Institute on Minority Health and Health Disparities (NIMHD)
  Completed
• The FOUNDATION Study

  NCT03939546

  Condition:   Preterm Infant
  Intervention:   Other: B. infantis EVC001
  Sponsor:   Evolve BioSystems, Inc.
  Recruiting
• Ideal Steroids for Asthma Treatment in the PICU

  NCT03900624

  Condition:   Asthma Childhood
  Intervention:   Drug: Dexamethasone
  Sponsor:   Johns Hopkins All Children's Hospital
  Enrolling by invitation
• Culturally Modified Family Based Therapy for Haitian Youth in South Florida

  NCT03876171

  Condition:   Problem Behavior
  Interventions:   Behavioral: Haitian youth and family intervention study: family functioning;   Behavioral: Haitian youth intervention study: youth psychoeducational;   Behavioral: Haitian family intervention study: family psychoeducational;   Behavioral: Diversion Programs
  Sponsors:   University of Miami;   National Institute on Drug Abuse (NIDA)
  Recruiting
• Targeting Burdensomeness Among Clinic Referred Youth

  NCT03781037

  Condition:   Perceived Burdensomeness Toward Others
  Intervention:   Behavioral: GIVE Module
  Sponsor:   Florida International University
  Recruiting
• Arterial Oxygen Saturation on Ventilatory Stability in Extremely Premature Infants

  NCT03695900

  Conditions:   Apnea of Prematurity;   Desaturation of Blood;   Central Apnea;   Periodic Breathing;   Obstructive Apnea of Newborn
  Interventions:   Other: Targeting SpO2 at 93-95%;   Other: Targeting SpO2 at 90-92%
  Sponsors:   University of Miami;   The Gerber Foundation
  Recruiting
• Evaluation of Trigeminal Nerve Blockade

  NCT03632044

  Conditions:   Mouth Abnormalities;   Cleft Palate;   Birth Defect
  Interventions:   Drug: Ropivacaine;   Other: Sham Comparator
  Sponsor:   University of Florida
  Enrolling by invitation
• Pharmacokinetic Study of DYANAVEL XR (Amphetamine) Extended-release Oral Suspension, in Children Aged 4 to 5 Years

  NCT03610464

  Condition:   Attention Deficit Hyperactivity Disorder
  Intervention:   Drug: Amphetamine Extended Release Suspension [Dyanavel]
  Sponsor:   Tris Pharma, Inc.
  Completed
• Inhaled Nitric Oxide for Pulmonary Hypertension and Bronchopulmonary Dysplasia

  NCT03576885

  Conditions:   Pulmonary Hypertension;   Bronchopulmonary Dysplasia
  Interventions:   Drug: inhaled nitric oxide;   Drug: Placebo
  Sponsors:   Florida Hospital;   Mallinckrodt;   Thrasher Research Fund
  Recruiting
• Improving Satisfaction, Engagement and Outcomes Among Traditionally Underserved Children Through Cultural Formulation

  NCT03499600

  Condition:   Disruptive Behavior
  Interventions:   Behavioral: Clinical Assessment and CFI;   Behavioral: Clinical Assessment
  Sponsors:   Florida International University;   University of Miami
  Completed
• PEARLS Intervention

  NCT03260062

  Condition:   Deafness, Bilateral
  Interventions:   Behavioral: Parent-Child Early Approaches to Raising Language Skills;   Other: Standard Care Speech therapy
  Sponsors:   University of Miami;   National Institute on Deafness and Other Communication Disorders (NIDCD)
  Recruiting
• Technology and Early Anxiety Treatment

  NCT03255122

  Condition:   Anxiety Disorders
  Interventions:   Behavioral: I-CALM;   Behavioral: Delayed I-CALM
  Sponsors:   Florida International University;   Andrew Kukes Foundation for Social Anxiety
  Recruiting
• Intranasal Oxytocin for Infants With Prader-Willi Syndrome

  NCT03245762

  Condition:   Prader-Willi Syndrome
  Interventions:   Drug: Oxytocin;   Drug: Placebo
  Sponsors:   University of Florida;   Prader-Willi Syndrome Association
  Completed
• Comparison of Primary Extubation Failure Between NIPPV and NI-NAVA

  NCT03242057

  Conditions:   Preterm Infant;   BPD - Bronchopulmonary Dysplasia;   Barotrauma
  Interventions:   Other: NAVA;   Other: NIPPV
  Sponsor:   University of Florida
  Completed
• A Crowdsourced Social Media Portal for Parents of Very Young Children With Type 1 Diabetes

  NCT03222180

  Condition:   Type 1 Diabetes Mellitus
  Intervention:   Behavioral: Website
  Sponsor:   Nemours Children's Clinic
  Active, not recruiting
• Methadone Demonstration Project

  NCT03134703

  Condition:   Neonatal Abstinence Syndrome
  Interventions:   Drug: Methadone;   Drug: Morphine
  Sponsors:   Johns Hopkins All Children's Hospital;   Florida Department of Health
  Terminated
• Efficacy of Auricular Acupuncture on Neonatal Abstinence Syndrome

  NCT02872077

  Condition:   Neonatal Abstinence Syndrome
  Intervention:   Other: Auricular acupuncture
  Sponsor:   University of South Florida
  Completed
• Antibiotic "Dysbiosis" in Preterm Infants

  NCT02784821

  Conditions:   Enterocolitis, Necrotizing;   Bacteremia;   Bronchopulmonary Dysplasia;   Intraventricular Hemorrhage;   Periventricular Leukomalacia;   Chronic Lung Disease;   Retinopathy of Prematurity;   Ileal Perforation
  Interventions:   Drug: Antibiotic;   Other: Gastric fluid;   Other: Breast milk;   Other: Stool samples;   Drug: Antibiotics - pre-emptive;   Other: Skin swabs
  Sponsors:   University of Florida;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   Society for Pediatric Dermatology
  Completed
• STAND Community Trial

  NCT02694939

  Condition:   Attention Deficit Hyperactivity Disorder
  Interventions:   Behavioral: STAND (Behavior Therapy + Motivational Interviewing);   Behavioral: Usual Care
  Sponsor:   Florida International University
  Active, not recruiting
• Treatment of Impulsive Aggression in Subjects With ADHD in Conjunction With Standard ADHD Treatment (CHIME 4)

  NCT02691182

  Condition:   Attention Deficit Hyperactivity Disorder (ADHD)
  Intervention:   Drug: SPN-810
  Sponsor:   Supernus Pharmaceuticals, Inc.
  Recruiting
• JUEGA: A Fun Study for Hispanic/Latino Adolescent Girls

  NCT02578147

  Condition:   Adolescent Behavior
  Interventions:   Behavioral: Mighty Girls;   Behavioral: Game Girls
  Sponsors:   University of Miami;   National Institute of Nursing Research (NINR)
  Terminated
• Intervention for Teens With ADHD and Substance Use

  NCT02502799

  Condition:   Attention Deficit Hyperactivity Disorder
  Interventions:   Behavioral: Brief Early Intervention;   Behavioral: Parent Training with Adolescent Cognitive Behavioral Therapy;   Drug: Methylphenidate
  Sponsor:   Florida International University
  Recruiting
• Respiratory Muscle Function in Untreated X-Linked Myotubular Myopathy (XLMTM)

  NCT02453152

  Condition:   X-linked Myotubular Myopathy
  Interventions:   Other: History and physical;   Other: Tidal breathing;   Other: Maximal respiratory pressures;   Other: Peak cough flow;   Other: Pediatric Evaluation of Disability Inventory;   Other: PedsQL Multidimensional Fatigue Scale;   Other: Review of ventilation requirements
  Sponsors:   University of Florida;   Audentes Therapeutics
  Completed
• A Within Subjects Comparison of Two Antegrade Flushing Regimens in Children

  NCT02435069

  Conditions:   Fecal Incontinence;   Neurogenic Bowel
  Interventions:   Drug: Dose Response - NS and USP Glycerin - First Intervention;   Drug: Effectiveness - NS and USP Glycerin - Second Intervention
  Sponsors:   Nemours Children's Clinic;   University of Florida
  Completed
• Improving Medication Adherence in ADHD Adolescents

  NCT02271880

  Condition:   ADHD
  Interventions:   Other: Medication as usual;   Other: STAR
  Sponsor:   Florida International University
  Terminated
• Assessment of Cardiopulmonary Function in Duchenne Muscular Dystrophy

  NCT02195999

  Condition:   Muscular Dystrophy, Duchenne
  Interventions:   Other: Magnetic Resonance Imaging (MRI);   Other: Pulmonary Function Testing (PFT);   Other: Metabolic Exercise Testing using stationary bicycle;   Other: Echocardiogram
  Sponsors:   University of Florida;   CureDuchenne
  Completed
• Acupuncture in Neonatal Abstinence Syndrome (NAS) Babies

  NCT02062151

  Condition:   Neonatal Abstinence Syndrome
  Intervention:   Other: Acupuncture
  Sponsor:   University of South Florida
  Completed
• Examining Tolerance to CNS Stimulants in ADHD

  NCT02039908

  Condition:   Attention-deficit/Hyperactivity Disorder
  Intervention:   Drug: Methylphenidate
  Sponsor:   Florida International University
  Active, not recruiting
• Early Detection of Progressive Kidney Disease in Preterm Infants

  NCT02000895

  Conditions:   Kidney Disease;   Cardiovascular Disease
  Intervention:  
  Sponsor:   University of Miami
  Recruiting
• Early iNO for Oxidative Stress, Vascular Tone and Inflammation in Babies With Hypoxic Respiratory Failure

  NCT01891500

  Conditions:   Persistent Fetal Circulation Syndrome;   Hypertension, Pulmonary, of Newborn, Persistent;   Persistent Pulmonary Hypertension of Newborn
  Interventions:   Drug: Inhaled nitric oxide;   Drug: Nitrogen Gas;   Drug: Crossover iNO
  Sponsors:   University of Florida;   Mallinckrodt
  Recruiting
• Parent Educational Program for Children With Sickle Cell Disease

  NCT00860782

  Conditions:   Hemoglobin SC Disease;   Anemia, Sickle Cell
  Intervention:   Behavioral: Parent Educational Support
  Sponsors:   University of Miami;   National Heart, Lung, and Blood Institute (NHLBI)
  Active, not recruiting
• Sleep and Emotional Memory in Peripubertal Anxiety

  NCT03643848

  Condition:   Anxiety
  Interventions:   Behavioral: Sleep with Sound Cues;   Behavioral: Sleep with Sham Cues
  Sponsor:   Florida International University
  Recruiting
• Exposure Therapy for Auditory Sensitivity in Autism

  NCT03206996

  Conditions:   Sensory Disorders;   Autism;   Autism Spectrum Disorder;   Autism With High Cognitive Abilities;   Autistic Behavior;   Hyperacusis
  Interventions:   Behavioral: Exposure therapy;   Behavioral: Psycho-education;   Behavioral: Caregiver education/home program development
  Sponsor:   University of Florida
  Completed
• Combination of Acetaminophen and Ibuprofen in the Management of Patent Ductus Arteriosus

  NCT03103022

  Conditions:   Patent Ductus Arteriosus;   Neonate
  Interventions:   Drug: Acetaminophen;   Drug: ibuprofen
  Sponsor:   University of Florida
  Completed
• Human Fibrinogen Concentrate in Pediatric Cardiac Surgery

  NCT02822599

  Conditions:   Hypofibrinogenemia;   Afibrinogenemia;   Bleeding Disorders
  Interventions:   Drug: RiaStAP;   Drug: Saline
  Sponsor:   Nicklaus Children's Hospital f/k/a Miami Children's Hospital
  Completed
• BIO-11006 for Osteosarcoma and Ewing's Sarcoma Lung Metastases

  NCT04183062

  Conditions:   Osteosarcoma Metastatic;   Ewing's Sarcoma Metastatic
  Intervention:   Drug: Chemotherapy (gemcitabine & docetaxel) plus BIO-11006
  Sponsor:   Nicklaus Children's Hospital f/k/a Miami Children's Hospital
  Recruiting
• Development of Novel Biomarkers for the Early Diagnosis of Type 1 Diabetes

  NCT04164966

  Condition:   Type 1 Diabetes
  Intervention:  
  Sponsor:   Translational Research Institute for Metabolism and Diabetes, Florida
  Not yet recruiting
• Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears

  NCT04088227

  Conditions:   Anterior Cruciate Ligament Tear;   Anterior Cruciate Ligament Rupture
  Interventions:   Drug: Experimental Group;   Other: Control Group
  Sponsor:   Andrews Research & Education Foundation
  Recruiting
• Prosthetic Device in Children With Upper Congenital Limb Deficiency

  NCT04059107

  Condition:   Upper Limb Deformities, Congenital
  Intervention:   Device: 3D Printed Myoelectric Prosthetic Device
  Sponsors:   Oregon Health and Science University;   Limbitless Solutions;   University of Central Florida
  Enrolling by invitation
• Investigating Event-Related Potentials and Eye-Tracking Measures in Hockey Players

  NCT03975023

  Conditions:   Healthy;   Traumatic Brain Injury
  Intervention:   Device: NeuroCatch Platform (NCP)
  Sponsors:   Frederick Carrick, PhD, FACCN;   HealthTech Connex Inc.
  Recruiting
• Observational Trial of the Impact of Radiation Dose in Children With Brain and Skull Base Tumors.

  NCT03972514

  Conditions:   Brain Tumor;   Brain Cancer;   Skull Base Tumor
  Intervention:  
  Sponsor:   Baptist Health South Florida
  Recruiting
• Lactobacillus Johnsonii in Children and Adolescents With T1D

  NCT03961854

  Condition:   Type 1 Diabetes (T1D)
  Interventions:   Drug: L. johnsonii Probiotic;   Drug: Placebo Capsule
  Sponsors:   University of Florida;   Juvenile Diabetes Research Foundation
  Recruiting
• Ex Vivo Drug Sensitivity Testing and Mutation Profiling

  NCT03860376

  Conditions:   Recurrent Childhood Acute Myeloid Leukemia;   Recurrent Childhood Acute Lymphoblastic Leukemia;   Recurrent Childhood Large Cell Lymphoma;   Refractory Childhood Acute Lymphoblastic Leukemia;   Refractory Childhood Hodgkin Lymphoma;   Refractory Childhood Malignant Germ Cell Neoplasm;   Recurrent Childhood Brain Tumor;   Recurrent Childhood Brainstem Glioma;   Recurrent Childhood Rhabdomyosarcoma;   Recurrent Childhood Soft Tissue Sarcoma;   Recurrent Childhood Ependymoma;   Recurrent Childhood Lymphoblastic Lymphoma;   Recurrent Childhood Gliosarcoma;   Refractory Chronic Myelogenous Leukemia, BCR-ABL1 Positive
  Intervention:  
  Sponsors:   Florida International University;   Nicklaus Children's Hospital f/k/a Miami Children's Hospital
  Recruiting
• Vorinostat Dose-escalation After Allogeneic Hematopoietic Cell Transplantation

  NCT03843528

  Conditions:   Acute Myeloid Leukemia;   Myelodysplastic Syndromes;   Mixed Phenotype Acute Leukemia;   Juvenile Myelomonocytic Leukemia
  Interventions:   Drug: Vorinostat;   Drug: Azacitidine Injection
  Sponsor:   Johns Hopkins All Children's Hospital
  Recruiting
• Diabetes Autoimmunity Withdrawn in New Onset Patients (DAWN)

  NCT03794973

  Condition:   Diabetes Mellitus, Type 1
  Interventions:   Biological: TOL-3021;   Other: TOL-3021 Placebo
  Sponsor:   Tolerion, Inc.
  Not yet recruiting
• Computer Assisted Family Intervention to Treat Self-Harm Disparities in Latinas and Sexual/Gender Minority Youth

  NCT03709472

  Conditions:   Self Harm;   Depression;   Emotion Dysregulation;   Behavior Problem
  Interventions:   Behavioral: Computer Assisted CIFFTA;   Behavioral: Behavioral: Traditional face-to-face treatment-no technology
  Sponsors:   University of Miami;   National Institute on Minority Health and Health Disparities (NIMHD)
  Recruiting
• Training Language and Literacy for Children Who Use CIs

  NCT03582566

  Condition:   Hearing Loss, Sensorineural
  Interventions:   Behavioral: Phonological Awareness;   Behavioral: Working Memory;   Behavioral: Phonological Awareness + Working Memory;   Behavioral: Active Control
  Sponsors:   Florida State University;   Northwestern University
  Recruiting
• Comparing Speedlyte and IV Rehydration Treating Children With Gastroenteritis in a Pediatric Emergency Department (ED)

  NCT03562702

  Conditions:   Dehydration;   Acute Gastroenteritis
  Interventions:   Other: Standard IV Rehydration Therapy;   Other: Oral Rehydration Therapy (ORT)
  Sponsors:   Nicklaus Children's Hospital f/k/a Miami Children's Hospital;   Einsoff Biohealth
  Recruiting
• Type 2 Diabetes and the Brain in Adolescents

  NCT03461510

  Conditions:   Type 2 Diabetes Mellitus;   Obesity;   Pediatric Obesity;   Insulin Resistance;   Dysglycemia;   Hyperglycemia
  Interventions:   Procedure: Hyperglycemic clamp;   Procedure: Hyperinsulinemic Euglycemic clamp
  Sponsor:   Nemours Children's Clinic
  Completed
• Diagnostic Odyssey: Whole Genome Sequencing (WGS)

  NCT03458962

  Conditions:   Genetic Disease;   Genetic Syndrome
  Intervention:   Genetic: Genetic Enrollees
  Sponsors:   Nicklaus Children's Hospital f/k/a Miami Children's Hospital;   Rady Pediatric Genomics & Systems Medicine Institute
  Enrolling by invitation
• Study of Stool Patterns to Collect a Panel of Stool Images for the Development of a Software

  NCT03402555

  Condition:   Healthy
  Intervention:   Other: Stool pattern
  Sponsors:   Danone Asia Pacific Holdings Pte, Ltd.;   ObvioHealth
  Active, not recruiting
• Microdystrophin Gene Transfer Study in Adolescents and Children With DMD

  NCT03368742

  Condition:   Duchenne Muscular Dystrophy
  Intervention:   Genetic: SGT-001
  Sponsor:   Solid Biosciences, LLC
  Suspended
• Adoptive Cellular Therapy in Pediatric Patients With High-grade Gliomas

  NCT03334305

  Condition:   Malignant Glioma
  Interventions:   Biological: TTRNA-DC vaccines with GM-CSF;   Drug: Dose-intensified TMZ;   Biological: Autologous Hematopoietic Stem cells (HSCs);   Biological: TTRNA-xALT;   Drug: Td vaccine
  Sponsors:   University of Florida;   National Pediatric Cancer Foundation;   National Cancer Institute (NCI);   Moffitt Clinical Research Network (MCRN);   National Institutes of Health (NIH)
  Recruiting
• Ketogenic Diet in Children With Malignant or Recurrent/Refractory Brain Tumor

  NCT03328858

  Condition:   Brain Tumors
  Intervention:   Other: Ketogenic Diet
  Sponsor:   Nicklaus Children's Hospital f/k/a Miami Children's Hospital
  Active, not recruiting
• Wellness Achieved Through Changing Habits (The WATCH Study)

  NCT03284788

  Conditions:   Weight Loss;   Obesity;   Overweight
  Intervention:   Behavioral: ABT Weight Loss Intervention
  Sponsors:   University of Florida;   StayWell;   National Heart, Lung, and Blood Institute (NHLBI);   WellCare Health Plans, Inc.
  Recruiting
• Skeletal Muscle and Adipose Tissue Study

  NCT03190668

  Condition:   Idiopathic Scoliosis
  Interventions:   Drug: Bolus dose of Cefazolin;   Drug: Continuous Cefazolin drip;   Device: Paraspinal muscle microdialysis catheters;   Device: Subcutaneous microdialysis catheters
  Sponsor:   University of Florida
  Recruiting
• Exploratory fMRI Study on the Treatment for Impulsive Aggression in Children With ADHD

  NCT03638466

  Condition:   Attention Deficit Hyperactivity Disorder (ADHD)
  Interventions:   Drug: SPN-810;   Drug: Placebo
  Sponsor:   Supernus Pharmaceuticals, Inc.
  Terminated
• Steroids in Children Hospitalized With Asthma

  NCT02780479

  Conditions:   Asthma;   Status Asthmaticus;   Wheezes
  Interventions:   Drug: Dexamethasone;   Drug: Prednisone
  Sponsor:   University of Florida
  Terminated
• Strata Programmable CSF Shunt Valve Study

  NCT02737163

  Condition:   Hydrocephalus
  Intervention:  
  Sponsor:   Johns Hopkins All Children's Hospital
  Terminated
• Influence of Monopoly Game on Subtle Behaviors

  NCT02729389

  Conditions:   Psychosocial Influence on Cardiovascular Disease;   Cardiovascular Disease
  Interventions:   Behavioral: High Social Status Condition;   Behavioral: Low Social Status Condition
  Sponsors:   University of Florida;   University of Alabama at Birmingham;   Brown University
  Completed
• Advancing Child Competencies by Extending Supported Services (ACCESS) for Families Program

  NCT03260816

  Conditions:   Developmental Delay;   Disruptive Behavior
  Interventions:   Behavioral: Internet-delivered Parent-Child Interaction Therapy (I-PCIT);   Other: Referrals as Usual (RAU)
  Sponsors:   Florida International University;   University of Miami;   Nicklaus Children's Hospital f/k/a Miami Children's Hospital;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
  Active, not recruiting
• Phase II Study of Intraventricular Methotrexate in Children With Recurrent or Progressive Malignant Brain Tumors

  NCT02684071

  Conditions:   Recurrent Childhood Medulloblastoma;   Recurrent Childhood Ependymoma;   Childhood Atypical Teratoid/Rhabdoid Tumor;   Embryonal Tumor With Abundant Neuropil and True Rosettes;   Metastatic Malignant Neoplasm to the Leptomeninges
  Interventions:   Drug: Intra thecal methotrexate;   Drug: topotecan;   Drug: cyclophosphamide
  Sponsor:   Nicklaus Children's Hospital f/k/a Miami Children's Hospital
  Active, not recruiting
• Safety, Efficacy, and Feasibility of High-dose Cholecalciferol in Pediatric Patients With Cystic Fibrosis

  NCT02613884

  Condition:   Vitamin D Deficiency
  Intervention:   Drug: Treatment
  Sponsor:   Johns Hopkins All Children's Hospital
  Completed
• Novel Mechanisms and Approaches to Treat Neonatal Sepsis

  NCT02554630

  Conditions:   Complication of Prematurity;   Immunologic Deficiency Syndromes
  Interventions:   Other: Adjuvant;   Other: Blood Collection
  Sponsors:   University of Florida;   National Institute of General Medical Sciences (NIGMS);   Surgical Infection Society
  Recruiting
• The OneFlorida Cancer Control Alliance: Implementing the 6As in Pediatric Primary Care

  NCT03044691

  Condition:   Smoking Cessation
  Intervention:   Behavioral: ResearchACTS software
  Sponsor:   University of Florida
  Terminated
• Anesthetic Optimization in Scoliosis Surgery

  NCT02481570

  Conditions:   Adolescent Idiopathic Scoliosis;   Respiratory Depression;   Postoperative Pain
  Intervention:   Other: pharmacokinetic simulation
  Sponsor:   University of Florida
  Completed
• Diet and Exercise in Pompe Disease

  NCT02363153

  Conditions:   Pompe Disease;   Glycogen Storage Disease Type II;   Lysosomal Storage Diseases
  Intervention:   Other: Diet and Exercise
  Sponsors:   University of Florida;   Amicus Therapeutics
  Recruiting
• Ketogenic Therapy Effects on Electrical and Metabolic Abnormalities in Epilepsy

  NCT02216500

  Condition:   Seizures
  Intervention:   Dietary Supplement: Ketogenic Therapy
  Sponsor:   University of Florida
  Recruiting
• Targeting Attention Orienting to Social Threat to Reduce Social Anxiety in Youth

  NCT03932032

  Condition:   Social Anxiety Disorder of Childhood
  Interventions:   Behavioral: Attention Bias Modification Treatment;   Behavioral: Neutral Control Task
  Sponsors:   Florida International University;   Yale University
  Recruiting
• Autologous Stem Cell Transplantation for Patients With Recurrent Nasopharyngeal Carcinoma

  NCT02137096

  Condition:   Recurrent Nasopharynx Carcinoma
  Interventions:   Drug: Etoposide phosphate;   Drug: Carboplatin;   Drug: Ifosfamide;   Procedure: Autologous Stem Cell Transplantation
  Sponsor:   University of Florida
  Terminated
• Open-Label Safety and PK Study of ER Hydromorphone Tablets in Opioid-Tolerant Pediatric Chronic Pain Patients

  NCT02321319

  Condition:   Chronic Pain
  Intervention:   Drug: Hydromorphone HCl ER Tablets
  Sponsor:   Mallinckrodt
  Terminated
• Attention Training to Modify Error-related Negativity and Risk for Anxiety in Adolescence

  NCT03176004

  Condition:   Anxiety
  Intervention:   Other: Attention Bias Modification
  Sponsors:   Florida State University;   San Diego State University
  Recruiting
• Proteinuria in Pre and Post Transplant

  NCT01094327

  Condition:   Proteinuria
  Intervention:  
  Sponsor:   University of Miami
  Recruiting
• Study of Irinotecan and Bevacizumab With Temozolomide in Refractory/Relapsed Central Nervous System (CNS) Tumors

  NCT00876993

  Condition:   Central Nervous System Tumors
  Interventions:   Drug: Bevacizumab;   Drug: Irinotecan;   Drug: Temozolomide
  Sponsors:   Johns Hopkins All Children's Hospital;   V Foundation;   Brain Tumor Alliance
  Completed
• Early Administration of Steroids in the Ambulance Setting

  NCT03962894

  Condition:   Asthma in Children
  Intervention:   Drug: Prednisolone
  Sponsor:   University of Florida
  Recruiting
• Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I)

  NCT03396575

  Condition:   Diffuse Intrinsic Pontine Glioma (DIPG)
  Interventions:   Biological: TTRNA-DC vaccines with GM-CSF;   Biological: TTRNA-xALT;   Drug: Cyclophosphamide + Fludarabine Lymphodepletive Conditioning;   Drug: Dose-Intensified TMZ;   Drug: Td vaccine;   Biological: Autologous Hematopoietic Stem Cells (HSC)
  Sponsors:   University of Florida;   Accelerate Brain Cancer Cure;   Lyla Nsouli Foundation
  Recruiting
• Pevonedistat With VXLD Chemotherapy for Adolescent/Young Adults With Relapsed/Refractory Acute Lymphoblastic Leukemia

  NCT03349281

  Conditions:   Refractory Acute Lymphoblastic Leukemia;   Relapsed Acute Lymphoblastic Leukemia
  Interventions:   Drug: Pevonedistat;   Drug: Vincristine;   Drug: Dexamethasone;   Drug: PEG-asparaginase;   Drug: Doxorubicin;   Drug: Cytarabine;   Drug: Methotrexate;   Drug: Hydrocortisone
  Sponsors:   Julio Barredo;   Takeda
  Recruiting
• Normative Oculomotor and Vestibular Data in Pediatric Population

  NCT04107610

  Condition:   Healthy
  Intervention:   Device: I-PAS
  Sponsors:   Neuro Kinetics;   Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute);   University of Miami
  Not yet recruiting
• Nab-paclitaxel in Combination With Gemcitabine for Pediatric Relapsed and Refractory Solid Tumors

  NCT03507491

  Condition:   Cancer
  Interventions:   Drug: Gemcitabine;   Drug: Nab-paclitaxel
  Sponsors:   Emory University;   Celgene Corporation
  Recruiting
• Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors

  NCT02644291

  Conditions:   Medulloblastoma;   Astrocytoma, Grade III;   Glioblastoma;   Anaplastic Astrocytoma;   Brain Stem Neoplasms, Malignant;   Oligodendroblastoma;   Anaplastic Oligodendroglioma;   Malignant Glioma
  Intervention:   Drug: Mebendazole
  Sponsor:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
  Recruiting
• A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or Observation After Radical Resection

  NCT01419067

  Condition:   Craniopharyngioma
  Interventions:   Procedure: Radical Surgery or Limited Surgery;   Device: Proton Therapy;   Drug: ^1^8F-fluorodeoxyglucose;   Drug: ^1^1C-methionine
  Sponsor:   St. Jude Children's Research Hospital
  Active, not recruiting
• Community Study of Outcome Monitoring for Emotional Disorders in Teens

  NCT02567266

  Conditions:   Depression;   Anxiety
  Interventions:   Behavioral: Unified Protocol for Adolescents (UP-A);   Behavioral: Youth Outcomes Questionnaire;   Behavioral: Treatment as Usual
  Sponsors:   University of Miami;   University of Connecticut;   National Institute of Mental Health (NIMH)
  Recruiting
• Computerized Cognitive Behavioral Therapy for Childhood Anxiety in Community Health Centers

  NCT01416805

  Conditions:   Generalized Anxiety Disorder;   Social Phobia;   Separation Anxiety Disorder
  Interventions:   Behavioral: Computerized Cognitive Behavioral Therapy;   Behavioral: Treatment as usual
  Sponsors:   University of South Florida;   Access Behavioral Health;   Henderson Behavioral Health;   Directions for Mental Health
  Completed
• Superficial Radiation Therapy (SRT) for the Treatment of Recurrent Keloid Scars

  NCT04184011

  Condition:   Keloid Scar
  Intervention:   Device: SRT-100™
  Sponsor:   Sensus Healthcare
  Recruiting
• Dupilumab for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine and Who Are naïve to, Intolerant of, or Incomplete Responders to Omalizumab

  NCT04180488

  Condition:   Chronic Spontaneous Urticaria
  Interventions:   Drug: Dupilumab SAR231893;   Drug: Placebo;   Drug: non sedating H1-antihistamine
  Sponsors:   Sanofi;   Regeneron Pharmaceuticals
  Recruiting
• Alpha-1 Research Registry

  NCT04157049

  Condition:   Alpha 1-Antitrypsin Deficiency
  Intervention:  
  Sponsor:   Alpha-1 Foundation
  Recruiting
• To Compare the Safety and Efficacy of Perrigo's Product to an FDA Approved Product for the Treatment of Secondarily Infected Traumatic Skin Lesions

  NCT04155203

  Condition:   Secondarily Infected Traumatic Skin Lesions
  Interventions:   Drug: Mupirocin Calcium;   Drug: Vehicle
  Sponsor:   Perrigo Company
  Recruiting
• Evaluation of Quality of Vision and Spectacle Independence With the AcrySof® Panoptix® Intraocular Lens

  NCT04124952

  Condition:   Cataract
  Intervention:   Device: Panoptix
  Sponsors:   SightTrust Eye Institute;   Science in Vision
  Enrolling by invitation
• Enhancing School-Based Violence Prevention

  NCT04087772

  Condition:   Aggressive Childhood Behavior
  Interventions:   Behavioral: Mental Health Enhanced Positive Behavioral Interventions and Supports (PBIS-MH);   Behavioral: Racial/Ethnic Discrimination Interventions (RED)
  Sponsors:   Medical University of South Carolina;   National Institute on Minority Health and Health Disparities (NIMHD)
  Recruiting
• Iron Absorption and Exercise

  NCT04079322

  Conditions:   Iron-deficiency;   Iron Deficiency Anemia
  Intervention:   Other: Meal
  Sponsor:   Florida State University
  Recruiting
• Tissue Oxygen Deprivation as Detected With Raman in Association With Umbilical Artery Catheters

  NCT04038203

  Condition:   Tissue Oxygenation
  Intervention:   Device: Resonance Raman Spectroscopy (RPS)
  Sponsor:   University of Florida
  Not yet recruiting
• Open-label Extension Study of Brazikumab in Crohn's Disease

  NCT03961815

  Condition:   Crohn's Disease
  Intervention:   Drug: Brazikumab
  Sponsor:   Allergan
  Enrolling by invitation
• Home Video-based Telemedicine to Reduce Hypoglycemia Fear in Parents of Young Children

  NCT03914547

  Condition:   Type 1 Diabetes Mellitus
  Interventions:   Behavioral: REDCHiP;   Behavioral: ATTN
  Sponsors:   University of Kansas Medical Center;   Children's Mercy Hospital Kansas City;   University of Florida;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  Recruiting
• Evidence-based Assessment of Medication Sensitivity in Acute Hepatic Porphyria

  NCT03906214

  Condition:   Porphyrias
  Intervention:   Other: Web-based Survey
  Sponsors:   University of South Florida;   University of Texas;   Wake Forest University Health Sciences;   University of Miami;   University of Washington;   Icahn School of Medicine at Mount Sinai;   University of Alabama at Birmingham;   University of California, San Francisco;   University of Utah;   National Institutes of Health (NIH)
  Completed
• Focused Cardiac Ultrasound

  NCT03887286

  Conditions:   Ventricular Dysfunction;   Pericardial Effusion;   Valvular Disease;   Septal Defect
  Interventions:   Device: Philips EPIQ 7 ultrasound machine;   Device: Philips Lumify Broadband sector array transducer
  Sponsor:   University of Miami
  Completed
• The Loop Observational Study

  NCT03838900

  Condition:   Diabetes Mellitus, Type 1
  Intervention:   Device: Loop
  Sponsors:   Jaeb Center for Health Research;   Stanford University;   Tidepool Project;   RileyLink
  Active, not recruiting
• A Study of S6G5T 3 in the Treatment of Acne Vulgaris

  NCT03761810

  Condition:   Acne Vulgaris
  Interventions:   Drug: S6G5T-3;   Drug: S6G5T-8
  Sponsor:   Sol-Gel Technologies, Ltd.
  Recruiting
• The Effect Of An Anesthetic Procedure On Post Operative Pain Management In Carpal Tunnel Release

  NCT03729375

  Conditions:   Pain, Postoperative;   Carpal Tunnel Syndrome
  Interventions:   Drug: 10cc injection of bupivacaine;   Drug: 20cc injection of bupivacaine
  Sponsor:   University of South Florida
  Recruiting
• A Study for a Topical Medication Versus Placebo in Patients With Hand Dermatitis

  NCT03703895

  Condition:   Hand Dermatitis
  Interventions:   Drug: Topical AFX5931;   Drug: Topical Placebo
  Sponsors:   The Center for Clinical and Cosmetic Research;   Afecta Pharmaceuticals
  Completed
• Diagnostic Odyssey Survey 2

  NCT03678740

  Condition:   Mitochondrial Diseases
  Intervention:   Other: Odyssey 2 Survey
  Sponsors:   University of South Florida;   Columbia University;   United Mitochondrial Disease Foundation;   George Washington University;   Massachusetts General Hospital
  Completed
• Omegaven as Alternative Parenteral Fat Nutrition

  NCT03662282

  Conditions:   Cholestasis;   Cholestasis of Parenteral Nutrition
  Intervention:   Drug: Omegaven
  Sponsor:   University of South Florida
  Completed
• Mission Reconnect- Delivering a Mobile and Web Based Self Directed Complementary And Integrative Health Program to Veterans and Their Partners to Manage Pain and PTSD

  NCT03593772

  Conditions:   PTSD;   Chronic Musculoskeletal Pain
  Intervention:   Behavioral: Mission Reconnect
  Sponsor:   VA Office of Research and Development
  Recruiting
• Adhear Bone Conduction System

  NCT03533686

  Conditions:   Hearing Loss, Conductive;   Hearing Loss, Unilateral
  Interventions:   Device: Adhear Bone Conduction System;   Device: Standard of Care
  Sponsors:   University of Miami;   Med-El Corporation
  Recruiting
• Pilot Study of OMEGA-3 and Vitamin D in High-Dose in Type I Diabetic Patients

  NCT03406897

  Conditions:   Diabetes Mellitus, Type 1;   Hypoglycemia;   Diabetes Mellitus;   Diabetes, Autoimmune
  Interventions:   Drug: Cholecalciferol;   Drug: Omega 3 fatty acid
  Sponsors:   Rodolfo Alejandro;   Diabetes Research Institute Foundation
  Recruiting
• A Study to Assess the Safety and Local Tolerability of DFD-03 (Tazarotene) Lotion, 0.1% Compared to Tazorac® (Tazarotene) Cream, 0.1% in the Topical Treatment of Acne Vulgaris

  NCT03341910

  Condition:   Acne Vulgaris
  Interventions:   Drug: Tazarotene Lotion, 0.1%;   Drug: Tazarotene Cream, 0.1%;   Drug: Vehicle Lotion 0%;   Drug: Vehicle Cream 0%
  Sponsor:   Dr. Reddy's Laboratories Limited
  Completed
• Clinical Endpoint Study of Ivermectin 0.5% Lotion

  NCT03301649

  Condition:   Head Lice
  Interventions:   Drug: Ivermectin Lotion 0.5%;   Drug: Placebo/Vehicle Lotion
  Sponsor:   Actavis Inc.
  Completed
• Friends/Family in the Abortion Procedure Room (FAIR)

  NCT03227614

  Conditions:   Anxiety;   Pain;   Abortion
  Intervention:   Behavioral: Support Person Intervention
  Sponsor:   Planned Parenthood of Southwest and Central Florida
  Completed
• Clinical Applications of Advanced Ophthalmic Imaging

  NCT03135327

  Conditions:   Multiple Sclerosis;   Dry Eye Syndromes;   Diabetic Retinopathy;   Presbyopia;   Myopia;   Dementia
  Intervention:   Other: No intervention
  Sponsor:   University of Miami
  Recruiting
• Pregnancy in Osteogenesis Imperfecta (OI) Registry

  NCT03072303

  Conditions:   Osteogenesis Imperfecta;   Brittle Bone Disorders
  Intervention:   Other: Web-based Survey
  Sponsors:   University of South Florida;   Rare Diseases Clinical Research Network;   National Institutes of Health (NIH)
  Completed
• Topical BPM31510 3.0% Cream in Patients With Epidermolysis Bullosa

  NCT02793960

  Condition:   Epidermolysis Bullosa
  Intervention:   Drug: topical BPM31510 3.0% Cream
  Sponsors:   Shasa Hu;   Berg, LLC
  Active, not recruiting
• Axitinib and Pembrolizumab in Subjects With Advanced Alveolar Soft Part Sarcoma and Other Soft Tissue Sarcomas

  NCT02636725

  Conditions:   Alveolar Soft Part Sarcoma;   Soft Tissue Sarcomas
  Interventions:   Drug: Axitinib;   Drug: Pembrolizumab;   Procedure: Blood Draw;   Procedure: Tumor Specimen Collection
  Sponsors:   Jonathan Trent;   Merck Sharp & Dohme Corp.;   Pfizer
  Active, not recruiting
• Pharmacokinetic Study in Children and Adolescents Aged 6 to 17 Years Who Have Been Diagnosed With ADHD

  NCT02578030

  Condition:   Attention-Deficit Hyperactivity Disorder (ADHD)
  Interventions:   Drug: SHP465 12.5mg;   Drug: SHP465 25mg
  Sponsor:   Shire
  Completed
• Biomarkers in Friedreich's Ataxia

  NCT02497534

  Condition:   Friedreich's Ataxia
  Intervention:  
  Sponsors:   University of Florida;   Children's Miracle Network;   National Institutes of Health (NIH);   Friedreich's Ataxia Research Alliance
  Recruiting
• Clinical Usability of Nasal Glucagon in Treatment of Hypoglycemia in Children and Adolescents

  NCT02402933

  Conditions:   Hypoglycemia;   Diabetes Mellitus
  Intervention:   Drug: Nasal Glucagon
  Sponsor:   Eli Lilly and Company
  Completed
• Electroencephalogram (EEG) Triggered Functional Magnetic Resonance Imaging (fMRI) in Epilepsy Patients

  NCT02193932

  Condition:   Epilepsy
  Intervention:   Other: EEG Triggered fMRI using Micro Maglink
  Sponsor:   Baptist Health South Florida
  Completed
• VCRC Patient Contact Registry Patient-Reported Data Validation Study

  NCT02190942

  Conditions:   Behcet's Disease;   Churg-Strauss Syndrome;   Giant Cell Arteritis;   Wegener Granulomatosis;   Microscopic Polyangiitis;   Polyarteritis Nodosa;   Takayasu's Arteritis
  Intervention:  
  Sponsors:   University of South Florida;   Wayne State University;   University of Pittsburgh;   University of Pennsylvania;   Boston University
  Completed
• Reducing Hospitalizations of Nursing Home Residents

  NCT02177058

  Condition:   Unnecessary Hospitalizations of Nursing Home Residents
  Interventions:   Other: INTERACT Quality improvement program;   Other: Quarterly surveys/data reporting
  Sponsors:   Florida Atlantic University;   National Institute of Nursing Research (NINR);   University of Minnesota
  Active, not recruiting
• Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy

  NCT02161380

  Condition:   Leber's Hereditary Optic Neuropathy
  Interventions:   Drug: injection of scAAV2-P1ND4v2 1.18x10e9 vg (Low),;   Drug: injection of scAAV2-P1ND4v2 5.81 X10e9 vg (Med);   Drug: injection of scAAV2-P1ND4v2 2.4 X10e10vg (High);   Drug: injection of scAAV2-P1ND4v2 1.0 X10e11vg (Higher)
  Sponsors:   John Guy;   National Eye Institute (NEI)
  Recruiting
• Deep Brain Stimulation Effects on Gait and Balance in Patients With Parkinson's Disease

  NCT02022735

  Condition:   Parkinson's Disease
  Intervention:   Device: Deep Brain Stimulation
  Sponsor:   University of Miami
  Active, not recruiting
• The Preeclampsia Registry

  NCT02020174

  Conditions:   Preeclampsia;   Eclampsia;   HELLP Syndrome;   Toxemia;   Hypertensive Disorder of Pregnancy
  Intervention:  
  Sponsor:   Preeclampsia Foundation
  Recruiting
• Liver Fibrosis in Sickle Cell Disease

  NCT02007746

  Condition:   Sickle Cell Disease
  Interventions:   Other: Liver transient elastography (Fibroscan);   Other: Ferriscan;   Procedure: Liver biopsy in iron overloaded subjects.
  Sponsor:   University of Miami
  Recruiting
• Blinded, Randomized Study Evaluating Aurstat Versus Control in the Treatment of Atopic Dermatitis Associated Pruritus

  NCT01905631

  Conditions:   Pruritus;   Atopic Dermatitis
  Intervention:   Drug: Aurstat Anti-Itch Hydrogel (Aurstat)
  Sponsors:   The Center for Clinical and Cosmetic Research;   Onset Dermatologics, Inc.
  Completed
• Dendritic Cell (DC) Vaccine for Malignant Glioma and Glioblastoma

  NCT01808820

  Conditions:   Malignant Glioma;   Glioblastoma Multiforme;   Anaplastic Astrocytoma;   High Grade Glioma
  Interventions:   Biological: Dendritic Cell Vaccine;   Biological: Tumor Lysate;   Other: Imiquimod;   Procedure: Leukapheresis
  Sponsor:   Macarena De La Fuente
  Active, not recruiting
• Dendritic Cell Vaccine With or Without Gemcitabine Pre-Treatment for Adults and Children With Sarcoma

  NCT01803152

  Conditions:   Sarcoma;   Soft Tissue Sarcoma;   Bone Sarcoma
  Interventions:   Biological: Dendritic Cells Vaccine;   Biological: Lysate of Tumor;   Drug: Gemcitabine;   Drug: Imiquimod;   Procedure: Leukapheresis
  Sponsor:   Macarena De La Fuente
  Active, not recruiting
• Evaluation of Adrenal Suppression Potential and Pharmacokinetics of Halobetasol Lotion 0.05%

  NCT03212963

  Condition:   Plaque Psoriasis
  Intervention:   Drug: Halobetasol Topical Lotion
  Sponsor:   Sun Pharmaceutical Industries Limited
  Completed
• Vaccine Combining Multiple Class I Peptides and Montanide ISA 51VG With Escalating Doses of Anti-PD-1 Antibody Nivolumab or Ipilimumab With Nivolumab For Patients With Resected Stages IIIC/ IV Melanoma

  NCT01176474

  Condition:   Melanoma (Skin)
  Interventions:   Biological: NY-ESO-1 157-165 (165V);   Drug: Nivolumab;   Biological: gp100:280-288 (288V);   Drug: Montanide ISA 51 vegetable grade (VG);   Drug: Ipilimumab;   Procedure: Apheresis Procedure
  Sponsors:   H. Lee Moffitt Cancer Center and Research Institute;   National Cancer Institute (NCI);   Medarex;   Bristol-Myers Squibb
  Active, not recruiting
• Multiple Class I Peptides & Montanide ISA 51 VG w Escalating Doses of Anti-PD-1 ab BMS936558

  NCT01176461

  Condition:   Melanoma (Skin)
  Interventions:   Biological: MART-1;   Biological: NY-ESO-1;   Biological: gp100:209-217(210M);   Biological: gp100:280-288(288V);   Drug: Montanide ISA 51 VG;   Biological: BMS-936558
  Sponsors:   H. Lee Moffitt Cancer Center and Research Institute;   National Cancer Institute (NCI);   Bristol-Myers Squibb;   Medarex
  Active, not recruiting
• The Insulin-Only Bionic Pancreas Bridging Study- Pediatric Transitional Study

  NCT04112069

  Condition:   Type1 Diabetes Mellitus
  Interventions:   Device: iLet Bionic Pancreas insulin-only configuration with Humalog or Novolog;   Other: Usual Care
  Sponsor:   Massachusetts General Hospital
  Completed
• Kuvan Therapy in Phenylketonuria (PKU): The Effect of Blood Phenylalanine Concentration on Kuvan Response

  NCT00841100

  Condition:   Phenylketonuria
  Interventions:   Drug: Kuvan;   Other: Diet
  Sponsor:   University of Miami
  Completed
• Florida Center for Brain Tumor Research

  NCT00811148

  Condition:   Brain Tumors
  Intervention:   Procedure: Tissue Bank
  Sponsor:   University of Florida
  Recruiting
• Biomechanics/Motion Analysis Laboratory Data Bank

  NCT00160771

  Condition:   Kinematics
  Intervention:   Behavioral: Joint Motion Analysis
  Sponsor:   University of Florida
  Recruiting
• Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Multiple Myeloma

  NCT00005792

  Conditions:   Multiple Myeloma;   Plasma Cell Neoplasm
  Interventions:   Drug: etoposide phosphate;   Drug: melphalan;   Drug: topotecan;   Procedure: Autologous Stem Cell Rescue
  Sponsors:   H. Lee Moffitt Cancer Center and Research Institute;   SmithKline Beecham;   Bristol-Myers Squibb
  Completed
• Adaptive Response to Intervention (RTI) for Students With ADHD

  NCT03511976

  Condition:   Attention Deficit Disorder With Hyperactivity
  Interventions:   Behavioral: Tier 1 Classroom Management;   Behavioral: Daily Report Card (DRC);   Behavioral: Enhanced DRC (DRC-E);   Drug: Stimulant
  Sponsors:   Florida International University;   University at Buffalo
  Recruiting
• Non-Invasive Detection of Tissue Oxygen Deprivation in Premature Infants With Patent Ductus Arteriosus.

  NCT03277768

  Conditions:   Premature Infant;   Patent Ductus Arteriosus;   Hemodynamic Instability
  Intervention:   Device: Resonance Raman Spectroscopy (RRS)
  Sponsors:   University of Florida;   Boston Children’s Hospital
  Completed
• A Study to Assess the Effectiveness of the Nautilus BrainPulse™ as an Aid in the Diagnosis of Concussion

  NCT02660164

  Condition:   Concussion
  Intervention:   Device: Nautilus BrainPulse Recording
  Sponsor:   Jan Medical, Inc.
  Recruiting
• Efficacy & Safety of STG320 Sublingual Tablets of HDM Allergen Extracts in Adults and Adolescents With HDM-associated AR

  NCT02443805

  Conditions:   Rhinitis, Allergic, Perennial;   House Dust Mite Allergy
  Interventions:   Biological: 300 IR;   Biological: Placebo
  Sponsor:   Stallergenes Greer
  Completed
• Incorporating teleCBIT Into a Hospital-Based Tic Program

  NCT04007913

  Conditions:   Tic Disorders;   Tourette Syndrome
  Intervention:   Behavioral: teleCBIT
  Sponsors:   San Jose State University;   American Academy of Neurology;   Tourette Association of America
  Completed
• Investigation of Neurocognitive Measures of Sport-Related Injury

  NCT03414242

  Condition:   Concussion, Brain
  Intervention:   Other: Cervical spine musculature
  Sponsor:   Mayo Clinic
  Enrolling by invitation
• Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy

  NCT01484678

  Condition:   Duchenne Muscular Dystrophy
  Intervention:  
  Sponsors:   University of Florida;   University of Pennsylvania;   Oregon Health and Science University;   Children's Hospital of Philadelphia;   Shriners Hospitals for Children;   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
  Recruiting
• Phase I Trial of Gene Vector to Patients With Retinal Disease Due to RPE65 Mutations

  NCT00481546

  Conditions:   Amaurosis of Leber;   Retinal Diseases
  Intervention:   Genetic: rAAV2-CBSB-hRPE65
  Sponsors:   University of Pennsylvania;   National Eye Institute (NEI)
  Active, not recruiting
• Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor

  NCT01326104

  Conditions:   Medulloblastoma;   Neuroectodermal Tumor
  Interventions:   Biological: TTRNA-xALT;   Biological: TTRNA-DCs
  Sponsors:   University of Florida;   United States Department of Defense
  Active, not recruiting
• Reversing Type 1 Diabetes After it is Established

  NCT01106157

  Condition:   Diabetes Mellitus, Type 1
  Interventions:   Drug: Anti-Thymocyte Globin (ATG);   Drug: Placebo;   Drug: Pegylated GCSF
  Sponsors:   University of Florida;   The Leona M. and Harry B. Helmsley Charitable Trust;   Genzyme, a Sanofi Company
  Completed
• Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy

  NCT01871766

  Condition:   Rhabdomyosarcoma
  Interventions:   Drug: Vincristine;   Drug: Dactinomycin;   Drug: Cyclophosphamide;   Procedure: Surgical Resection;   Procedure: Radiation;   Drug: Bevacizumab;   Drug: Sorafenib;   Drug: Myeloid Growth Factor;   Procedure: Lymph Node Sampling;   Drug: Irinotecan;   Drug: Ifosfamide;   Drug: Etoposide;   Drug: Etoposide Phosphate;   Drug: Doxorubicin;   Drug: Dexrazoxane;   Drug: ^1^1C-methionine
  Sponsor:   St. Jude Children's Research Hospital
  Recruiting
• A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis

  NCT03987763

  Condition:   Psoriasis
  Intervention:   Drug: IDP-122 Lotion
  Sponsor:   Bausch Health Americas, Inc.
  Recruiting
• A Study to Assess the Pharmacokinetics (PK), Pharmacodynamics (PD) and Safety of 2-Week Treatment With Inhaled AZD7594 in Adolescents (12 to 17 Years) With Asthma

  NCT03976869

  Condition:   Asthma
  Intervention:   Drug: AZD7594
  Sponsors:   AstraZeneca;   Parexel
  Recruiting
• A Food Additive Removal Diet for Pediatric Eosinophilic Esophagitis

  NCT03657771

  Condition:   Eosinophilic Esophagitis
  Interventions:   Other: DED;   Other: FREE
  Sponsor:   Nemours Children's Clinic
  Recruiting
• Glycemic Control and the Brain in Children With Type 1 Diabetes

  NCT03428932

  Condition:   Type 1 Diabetes Mellitus
  Intervention:   Device: Closed Loop (Medtronic 670G)
  Sponsors:   Nemours Children's Clinic;   National Institutes of Health (NIH);   Washington University School of Medicine;   Stanford University;   University of Iowa;   Yale University;   Jaeb Center for Health Research
  Completed
• Remote Monitoring of Diabetes in Young Children With Type 1 Diabetes

  NCT02848261

  Condition:   Type 1 Diabetes Mellitus
  Interventions:   Behavioral: Developmental Demands;   Behavioral: Distress Reduction;   Behavioral: Remote Monitoring;   Behavioral: Fear of Hypoglycemia;   Behavioral: No intervention
  Sponsors:   Stanford University;   University of Colorado, Denver;   Indiana University;   University of South Florida
  Completed
• Intense Physiotherapies to Improve Function in Young Children With Cerebral Palsy

  NCT02167022

  Condition:   Cerebral Palsy
  Intervention:   Other: Physical and occupational therapy
  Sponsors:   University of Arizona;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   Tucson Medical Center;   Phoenix Children's Hospital;   United Cerebral Palsy-Central Arizona;   Nemours Children's Hospital
  Active, not recruiting
• Phase 1/2 Study in Boys With Duchenne Muscular Dystrophy

  NCT02439216

  Condition:   Muscular Dystrophy, Duchenne
  Interventions:   Drug: Edasalonexent;   Drug: Placebo
  Sponsor:   Catabasis Pharmaceuticals
  Completed
• Implementing a Healthcare Provider Education Intervention in Rural Communities to Reduce Asthma Morbidity

  NCT04060823

  Condition:   Asthma
  Intervention:   Other: Easy Breathing program
  Sponsor:   University of Florida
  Recruiting
• Teacher Child Interaction Training (TCIT): Randomized Control Trial

  NCT04000230

  Condition:   Behavior, Child
  Interventions:   Behavioral: TCIT;   Behavioral: Booster
  Sponsors:   University of Miami;   The Children's Trust
  Recruiting
• Spanish Intervention for Caregivers of Veterans With Stroke

  NCT03142841

  Condition:   Depression
  Intervention:   Other: RESCUE Problem Solving Intervention
  Sponsor:   VA Office of Research and Development
  Recruiting
• Intervention to Expand Opioid Use Disorder Treatment Pharmacotherapy Prescribers

  NCT02926482

  Condition:   Opioid-use Disorder
  Intervention:   Behavioral: Prescriber Recruitment Bundle (PRB)
  Sponsors:   University of Wisconsin, Madison;   National Institute on Drug Abuse (NIDA)
  Active, not recruiting
• Statins in Children With Type 1 Diabetes and Hypercholesterolemia

  NCT01236365

  Conditions:   Diabetes Mellitus, Insulin-Dependent;   Hypercholesterolemia
  Interventions:   Drug: Atorvastatin;   Drug: Atorvastatin Placebo
  Sponsors:   Nemours Children's Clinic;   Pfizer;   Medtronic;   Quest Diagnostics
  Completed
• A Phase 2 Study for Dose Determination of SRP-5051, Then Dose Expansion in Patients With Duchenne Muscular Dystrophy Amenable to Exon 51-Skipping Treatment

  NCT04004065

  Condition:   Duchenne Muscular Dystrophy
  Intervention:   Drug: SRP-5051
  Sponsor:   Sarepta Therapeutics, Inc.
  Recruiting
• Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma

  NCT03739372

  Conditions:   Glioma;   Glioma of Brain;   Cancer;   Pediatric Cancer;   Pediatric Brain Tumor;   Astrocytoma;   Glioblastoma;   Hemispheric
  Intervention:   Other: Specialized tumor board recommendation
  Sponsors:   University of California, San Francisco;   Pacific Pediatric Neuro-Oncology Consortium
  Recruiting
• PRC-063 Classroom Study in Children (6-12 Years of Age) With ADHD

  NCT03172481

  Condition:   ADHD
  Interventions:   Drug: PRC-063 oral capsules;   Drug: Placebo oral capsules
  Sponsor:   Purdue Pharma, Canada
  Completed
• Protocol to Monitor the Neurological Development of Infants With Exposure in Utero From Birth to 15 Months in Tanezumab Clinical Studies

  NCT03031938

  Conditions:   Osteoarthritis;   Cancer Pain;   Recurrent Low Back Pain
  Intervention:   Drug: Investigational medical product (IMP) administered in parent study
  Sponsors:   Pfizer;   Eli Lilly and Company
  Active, not recruiting
• Robotic vs. Freehand Corrective Surgery for Pediatric Scoliosis

  NCT02084264

  Condition:   Scoliosis
  Intervention:  
  Sponsor:   Mazor Robotics
  Terminated
• To Assess Safety, Tolerability and Physiological Effects on Structure and Function of AXA4010 in Subjects With Sickle Cell Disease

  NCT04134299

  Conditions:   To Assess the Safety and Tolerabiltiy of an Amino Acid Composition in Subjects With Sickle Cell Disease;   Anemia, Sickle Cell;   Sickle Cell Anemia;   Sickle Cell Disorders;   Sickle Cell Disease
  Intervention:   Dietary Supplement: AXA4010
  Sponsor:   Axcella Health, Inc
  Recruiting
• Myopia Assessment of Two Manufacturing Processes

  NCT04126057

  Condition:   Juvenile Myopia
  Intervention:   Device: SightGlass Vision DOT Spectacle Lenses
  Sponsor:   SightGlass Vision, Inc.
  Recruiting
• Expanded Indications in the MED-EL Pediatric Cochlear Implant Population

  NCT03900897

  Condition:   Hearing Loss, Sensorineural
  Intervention:   Device: MED-EL SYNCHRONY PIN Cochlear Implant
  Sponsor:   Med-El Corporation
  Recruiting
• A Study of Lymphoseek® as a Lymphoid Tissue Targeting Agent in Pediatric Patients With Melanoma, Rhabdomyosarcoma, or Other Solid Tumors Who Are Undergoing Lymph Node Mapping

  NCT02509598

  Conditions:   Rhabdomyosarcoma;   Melanoma
  Interventions:   Drug: Tc99m tilmanocept;   Drug: Vital Blue Dye (optional)
  Sponsor:   Cardinal Health 414, LLC
  Completed
• Gastrointestinal Tract Microbiome in Healthy Term Infants Receiving Mother'S-own Breast Milk or Cow's Milk-based Infant Formulas

  NCT04059666

  Condition:   Gastrointestinal Microbiome
  Interventions:   Other: Investigational;   Other: Control
  Sponsor:   Mead Johnson Nutrition
  Recruiting
• iKanEat: A Randomized-controlled, Multi-center Trial of Megestrol for Chronic Oral Food Refusal in Children

  NCT03815019

  Conditions:   Feeding Behavior;   Feeding Disorder of Infancy or Early Childhood
  Interventions:   Drug: Megestrol Acetate;   Behavioral: iKanEat Behavioral Intervention
  Sponsor:   University of Kansas Medical Center
  Recruiting
• Oropharyngeal Administration of Mother's Colostrum for Premature Infants

  NCT02116699

  Conditions:   Infection;   Enterocolitis, Necrotizing;   Ventilator-associated Pneumonia
  Interventions:   Other: oropharyngeal mother's milk;   Other: oropharyngeal sterile water
  Sponsors:   NorthShore University HealthSystem;   The Gerber Foundation;   Fundacion Para La Investigacion Hospital La Fe;   University of Chicago
  Recruiting
• Standard Lipid Therapy vs IVFE Minimization for Prevention of PNALD

  NCT02357576

  Condition:   Cholestasis
  Intervention:   Drug: Intralipid 20% I.V. Fat Emulsion
  Sponsors:   University of Michigan;   Seattle Children's Hospital;   University of Florida;   Primary Children's Hospital;   University of Colorado, Denver
  Terminated
• eHealth Evidence-based Intervention (EBI) for Latino Youth in Primary Care

  NCT03009539

  Conditions:   Sexual Risk Behavior;   Drug Use;   Family Functioning
  Intervention:   Behavioral: eHealth Familias Unidas Primary Care
  Sponsors:   University of Miami;   National Institute on Drug Abuse (NIDA)
  Active, not recruiting
• A Study to Test if TEV-50717 is Effective in Relieving Tics Associated With Tourette Syndrome

  NCT03571256

  Condition:   Tourette Syndrome
  Interventions:   Drug: deutetrabenazine Low;   Drug: deutetrabenazine High;   Drug: Placebo
  Sponsors:   Teva Branded Pharmaceutical Products, R&D Inc.;   Nuvelution TS Pharma, Inc.
  Active, not recruiting
• A Study of Galcanezumab (LY2951742) in Participants 6 to 17 Years of Age With Episodic Migraine

  NCT03432286

  Condition:   Episodic Migraine
  Interventions:   Drug: Galcanezumab;   Drug: Placebo
  Sponsor:   Eli Lilly and Company
  Recruiting
• Evaluate the Safety of a Single Oral Dose of Solosec™ (Secnidazole) 2g for the Treatment of Adolescent Girls With BV

  NCT03937869

  Condition:   Bacterial Vaginoses
  Intervention:   Drug: Secnidazole
  Sponsor:   Lupin Research Inc
  Recruiting
• Investigation of Cognitive Outcomes With Cannabidiol Oral Solution

  NCT04133480

  Condition:   Lennox-Gastaut Syndrome
  Intervention:   Drug: GWP42003-P
  Sponsor:   GW Research Ltd
  Not yet recruiting
• Effects of a Orally Inhaled Fluticasone Furoate on Growth Velocity in Prepubertal, Paediatric Subjects With Asthma Over a Year

  NCT02889809

  Condition:   Asthma
  Interventions:   Drug: Fluticasone furoate;   Drug: Placebo;   Drug: Montelukast;   Drug: Short Acting Beta 2 Agonist
  Sponsor:   GlaxoSmithKline
  Recruiting
• IBP-9414 for the Prevention of Necrotizing Enterocolitis - The Connection Study

  NCT03978000

  Condition:   Necrotizing Enterocolitis
  Interventions:   Drug: IBP-9414;   Drug: Placebo
  Sponsor:   Infant Bacterial Therapeutics
  Recruiting
• KP415 Open-Label Safety Study in Children (6-12 Years of Age) With ADHD

  NCT03460652

  Condition:   ADHD
  Intervention:   Drug: KP415 oral capsule
  Sponsor:   KemPharm, Inc.
  Completed
• Growth and Tolerance of Young Infants Fed Infant Formula

  NCT04105686

  Condition:   Growth and Tolerance
  Interventions:   Other: Control Infant Formula;   Other: Experimental Infant Formula
  Sponsor:   Abbott Nutrition
  Recruiting
• Patient Perception of Treatment Burden in Weekly Versus Daily Growth Hormone Injections in Children With GHD

  NCT03831880

  Condition:   Growth Hormone Deficiency
  Interventions:   Drug: Genotropin;   Drug: somatrogon
  Sponsor:   Pfizer
  Recruiting
• A Study of Escitalopram in the Treatment of Children and Adolescents With Generalized Anxiety Disorder

  NCT03924323

  Conditions:   Anxiety Disorders;   Generalized Anxiety Disorder
  Interventions:   Drug: Escitalopram;   Other: Placebo
  Sponsor:   Allergan
  Recruiting
• Treatment of Impulsive Aggression (IA) in Adolescent With ADHD in Conjunction With Standard ADHD Treatment

  NCT03597503

  Condition:   Attention Deficit Hyperactivity Disorder
  Interventions:   Drug: SPN-810;   Drug: Placebo
  Sponsor:   Supernus Pharmaceuticals, Inc.
  Recruiting
• JAK1 Inhibitor With Medicated Topical Therapy in Adolescents With Atopic Dermatitis

  NCT03796676

  Condition:   Atopic Dermatitis
  Interventions:   Drug: Placebo;   Drug: PF-04965842;   Drug: PF04965842
  Sponsor:   Pfizer
  Recruiting
• Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US

  NCT03537508

  Condition:   Meningococcal Infections
  Interventions:   Biological: MenACYW conjugate vaccine;   Biological: MenACYW-135 conjugate vaccine;   Biological: DTaP-IPV//Hib vaccine;   Biological: Pneumococcal 13-valent conjugate vaccine;   Biological: Pentavalent rotavirus vaccine;   Biological: Hepatitis B vaccine;   Biological: Measles, mumps, rubella (MMR) vaccine;   Biological: Varicella vaccine;   Biological: Hepatitis A vaccine
  Sponsor:   Sanofi Pasteur, a Sanofi Company
  Recruiting
• Safety and Efficacy of NBI-98854 in Pediatric Subjects With Tourette Syndrome

  NCT03530293

  Condition:   Tourette Syndrome
  Interventions:   Drug: Valbenazine;   Drug: Placebo oral capsule
  Sponsor:   Neurocrine Biosciences
  Terminated
• Efficacy and Safety of SHP465 at 6.25 mg in the Treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in Children Aged 6-12 Years

  NCT03325881

  Condition:   Attention Deficit Hyperactivity Disorder (ADHD)
  Interventions:   Drug: SHP465;   Drug: Placebo
  Sponsor:   Shire
  Completed
• Safety of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

  NCT03673462

  Condition:   Healthy Volunteers (Meningococcal Infection)
  Interventions:   Biological: Meningococcal polysaccharide (serogroups A,C,Y and W) tetanus toxoid conjugate vaccine (MenACYW conjugate vaccine);   Biological: Meningococcal (Groups A, C, Y and W 135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine (MENVEO®);   Biological: Diphtheria, Tetanus, Acellular Pertussis, Poliovirus and Haemophilus b Vaccine;   Biological: Pneumococcal 13-valent Conjugate Vaccine;   Biological: Rotavirus Vaccine;   Biological: Hepatitis B Vaccine;   Biological: Measles, Mumps, and Rubella Virus Vaccine;   Biological: Varicella Virus Vaccine
  Sponsor:   Sanofi Pasteur, a Sanofi Company
  Recruiting
• Safety and Efficacy Study of Fluticasone Furoate/Vilanterol (FF/VI) Fixed Dose Combination (FDC) Compared to FF Alone in Subjects With Asthma

  NCT03248128

  Condition:   Asthma
  Interventions:   Drug: FF/VI via ELLIPTA DPI;   Drug: FF via ELLIPTA DPI
  Sponsor:   GlaxoSmithKline
  Recruiting
• A Study to Evaluate the Safety and Efficacy of MEDI8897 for the Prevention of Medically Attended RSV LRTI in Healthy Late Preterm and Term Infants

  NCT03979313

  Condition:   Respiratory Syncytial Virus Infections
  Interventions:   Drug: MEDI8897;   Drug: Placebo
  Sponsor:   MedImmune LLC
  Recruiting
• Diabetes Study of Linagliptin and Empagliflozin in Children and Adolescents (DINAMO)TM

  NCT03429543

  Condition:   Diabetes Mellitus, Type 2
  Interventions:   Drug: Linagliptin;   Drug: Empagliflozin;   Drug: Placebo
  Sponsor:   Boehringer Ingelheim
  Recruiting
• Efficacy, Safety, and Tolerability of Levomilnacipran ER in Pediatric (7-17 Years) With Major Depressive Disorder

  NCT03569475

  Condition:   Major Depressive Disorder
  Interventions:   Drug: Levomilnacipran ER;   Drug: Fluoxetine;   Drug: Placebo
  Sponsor:   Allergan
  Recruiting
• Efficacy & Safety Of Zomig Nasal Spray For Acute Migraine Treatment In Subjects 6 To 11 Years, With OLE

  NCT03275922

  Condition:   Migraine
  Interventions:   Drug: Placebo ZNS;   Drug: ZNS
  Sponsors:   Impax Laboratories, LLC;   AstraZeneca
  Recruiting
• Extension Study Evaluating The Safety And Tolerability Of Flexible Doses Of Oral Ziprasidone In Children And Adolescents With Bipolar I Disorder

  NCT03768726

  Condition:   Bipolar Disorder
  Intervention:   Drug: Ziprasidone
  Sponsor:   Pfizer
  Recruiting
• Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

  NCT03691610

  Condition:   Healthy Volunteers (Meningococcal Infection)
  Interventions:   Biological: Meningococcal Polysaccharide (Serogroups A,C,Y and W) Tetanus Toxoid Conjugate vaccine MenACYW conjugate vaccine;   Biological: Meningococcal (Groups A, C, Y and W 135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine;   Biological: Meningococcal Polysaccharide (serogroups A,C,Y and W-135) Diphtheria Toxoid Conjugate Vaccine;   Biological: Diphtheria and Tetanus Toxoids and Acellular Pertussis, inactivated Poliovirus and Haemophilus b Conjugate Vaccine;   Biological: Diphtheria and Tetanus Toxoids and Acellular Pertussis, Hepatitis B and Inactivated Poliovirus Vaccine;   Biological: Haemophilus b Conjugate Vaccine;   Biological: Pneumococcal 13-valent Conjugate Vaccine;   Biological: Rotavirus Vaccine, Live, Oral, Pentavalent;   Biological: Hepatitis B Vaccine;   Biological: Measles, Mumps, and Rubella Virus Vaccine Live;   Biological: Varicella Virus Vaccine Live
  Sponsor:   Sanofi Pasteur, a Sanofi Company
  Recruiting