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Ellijay, Georgia 30536
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Relationship-based Care Model in Pediatrics
NCT04199429
Conditions: Depression, Anxiety; Nurse-Patient Relations
Intervention: Behavioral: Relationship-Based Care
Sponsors: University of Urbino "Carlo Bo"; University of Padua
Completed
Effectiveness of a Mobile App for Individuals With or at Risk of Knee Osteoarthritis
NCT04199416
Conditions: Knee Pain/Osteoarthritis; Digital Health
Interventions: Device: mRehab app; Device: Sham app
Sponsor: The University of Hong Kong
Not yet recruiting
Assessment of Complication Risk Factors in a French National Cohort of Asplenic Patients
NCT04199403
Condition: Asplenia
Intervention:
Sponsors: Poitiers University Hospital; Pr Pierre BUFFET Institut National de la Transfusion Sanguine; Pr Sophie CANDON Laboratoire d'immunologie et biothérapies CHU de Rouen; Dr Edouard TUAILLON Département Bactériologie-Virologie/INSERM U1058 CHU de Montpellier
Not yet recruiting
Physical Therapy Following Total Hip Arthroplasty
NCT04199390
Conditions: Hip Osteoarthritis; Surgery
Intervention: Procedure: total hip arthroplasty
Sponsors: Orthopedic One; Medacta USA
Completed
Retrospective Evaluation of Clinical and Functional Results and Survivorship of Total Knee Replacement and Total Hip Replacement, Both Isolated or Combined.
NCT04199377
Conditions: HIP REPLACEMENT; KNEE REPLACEMENT
Intervention: Procedure: HIP KNEE REPLACEMENT
Sponsor: Istituto Ortopedico Galeazzi
Recruiting
Medium vs Low Oxygen Threshold for the Surfactant Administration
NCT04199364
Condition: Respiratory Distress Syndrome
Intervention: Drug: Poractant Alfa 80 mg/mL Intratracheal Suspension
Sponsor: Virgilio Paolo Carnielli
Not yet recruiting
Single and Multiple Ascending Dose Study of AMG 171 in Subjects With Obesity
NCT04199351
Condition: Obesity
Interventions: Drug: AMG 171; Drug: Placebo
Sponsor: Amgen
Not yet recruiting
The Effect of Web Based Education Based on Self-Care Deficiency Theory on Self-Care Power and Self-Efficacy and Perceived Social Support in Patients Receiving Peritoneal Dialysis
NCT04199338
Conditions: Self-Care; Self Efficacy; Perceived Social Support; Peritoneal Dialysis
Intervention: Other: The Effect of Web Based Education Based on Self-Care Deficiency Theory on Self-Care Power and Self-Efficacy and Perceived Social Support in Patients Receiving Peritoneal Dialysis
Sponsor: Akdeniz University
Enrolling by invitation
Probiotics for Gout / Hyperuricemia: Randomized, Double-blind, Intervention, Parallel Controlled, Multicenter
NCT04199325
Conditions: Gout; Hyperuricemia
Interventions: Dietary Supplement: Probiotics; Drug: uric-acid-lowering drug
Sponsor: The Affiliated Hospital of Inner Mongolia Medical University
Recruiting
Magnetic Muscle Stimulation of Abdominal Muscle
NCT04199312
Condition: Body Fat Disorder
Intervention: Device: The ZELTIQ System
Sponsor: Zeltiq Aesthetics
Active, not recruiting
Sensors for Communication for Persons Who Cannot Communicate Unequivocally
NCT04199299
Conditions: Intellectual Disability; Autism; Cerebral Palsy
Intervention: Device: Heart rate and respiration rate sensors
Sponsor: University of Oslo
Recruiting
Horizontal Strabismus Surgery
NCT04199286
Condition: Strabismus
Intervention: Procedure: symmetrical and asymmetrical horizontal strabismus surgery
Sponsor: Minia University
Completed
Assessment of Human Diaphragm Strength by Magnetic and Electric Stimulation After Ultrasonography Phrenic Nerve Tracking
NCT04199273
Conditions: Intensive Care Unit; Invasive Mechanical Ventilation
Interventions: Procedure: Magnetic stimulation; Procedure: Electric stimulation
Sponsor: University Hospital, Montpellier
Not yet recruiting
Investigation to Evaluate PAPILOCARE® Gel Effect on Normalization of Cervix Cytological Alterations Caused by HPV.
NCT04199260
Conditions: HPV Infection; Lesion Cervix
Intervention: Device: papilocare vaginal gel
Sponsors: Procare Health Iberia S.L.; Adknoma Health Research
Recruiting
Early Exercise to Improve Psychosocial Function After Pediatric Mild Traumatic Brain Injury
NCT04199247
Conditions: Brain Concussion; Pediatric; Mild Traumatic Brain Injury; Psychological
Intervention: Behavioral: Sub symptom aerobic exercise
Sponsor: University of Colorado, Denver
Not yet recruiting
Tolerability of AB-Fortis Encapsulated Iron
NCT04199234
Condition: Supplement
Interventions: Dietary Supplement: experimental product consumption. (AB Fortis 60 mg); Dietary Supplement: comparator product consumption. (Iron sulphate.)
Sponsor: Universidad Católica San Antonio de Murcia
Not yet recruiting
Use of Stress Inoculation Training in Medical Education
NCT04199221
Condition: Stress
Interventions: Behavioral: Stress Innoculation Training (SIT); Behavioral: Extra attempt
Sponsor: Virginia Commonwealth University
Not yet recruiting
Does Prehabilitation Improve Outcome in Coloncancer Surgery?
NCT04199208
Condition: Surgery--Complications
Interventions: Other: Prehabilitation and Immunonutrition; Other: Standard Care Arm
Sponsor: Region Skane
Not yet recruiting
Microbiome of the Ageing Gut and Its Effect on Human Gut Health and Cognition.
NCT04199195
Condition: Ageing
Intervention:
Sponsors: Quadram Institute Bioscience; Norfolk and Norwich University Hospitals NHS Foundation Trust
Enrolling by invitation
Exercise Training to Improve PTSD Symptoms and Health in Older Veterans
NCT04199182
Condition: Post-traumatic Stress Disorder
Interventions: Behavioral: Exercise Training; Other: Healthy Aging Attention Control (HA-ATC)
Sponsor: VA Office of Research and Development
Not yet recruiting
Safety and Immunogenicity of a Nipah Virus Vaccine
NCT04199169
Condition: Nipah Virus Infection
Interventions: Biological: HeV-sG-V; Biological: Normal Saline Placebo
Sponsors: Profectus BioSciences, Inc.; PATH; Coalition for Epidemic Preparedness Initiative (CEPI); Cincinnati Children's Hospital Medical Center (CCHMC)
Not yet recruiting
Evaluation of Non-invasive Blood Pressure Measured at the Ankle During Cesarean Delivery Compared to the Arm
NCT04199156
Conditions: Non-invasive Blood Pressure; Cesarean Delivery; Spinal Anesthesia
Intervention:
Sponsor: Kasr El Aini Hospital
Not yet recruiting
Brain Reactivity to Nitrous Oxyde in Depression : an MRI and Ultrasound Study (PROTOBRAIN Pilote)
NCT04199143
Conditions: Treatment Resistant Depression; Nitrous Oxyde
Interventions: Drug: Nitrous Oxide-Oxygen; Device: Tissue Pulsatility Imaging - TPI; Device: Magnetic Resonance Imaging - MRI
Sponsor: University Hospital, Tours
Not yet recruiting
Cognitive Rehabilitation and Brain Activity of Attention-Control Impairment in TBI
NCT04199130
Condition: Traumatic Brain Injury
Interventions: Behavioral: BrainHQ; Behavioral: Goal Management Training
Sponsor: Catherine Tocci
Not yet recruiting
Health Systems Reach Interventions Project
NCT04199117
Conditions: Smoking, Cigarette; Smoking Cessation
Interventions: Drug: Varenicline; Drug: Combination nicotine patch and nicotine mini-lozenge treatment; Behavioral: Monetary incentives for initiating treatment; Behavioral: Automated tailored outreach; Behavioral: Care management; Other: Wisconsin Tobacco Quit Line referral; Other: Primary care provider referral; Behavioral: Untailored outreach; Behavioral: Multiple smoking cessation coaching calls
Sponsors: University of Wisconsin, Madison; National Cancer Institute (NCI)
Not yet recruiting
A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (LEAP-010) (MK-7902-010)
NCT04199104
Condition: Head and Neck Squamous Cell Carcinoma
Interventions: Drug: Lenvatinib; Drug: Pembrolizumab; Drug: Placebo
Sponsor: Merck Sharp & Dohme Corp.
Not yet recruiting
Craniosacral Therapy as a Self-help Strategy for Patients With Chronic Non-specific Back Pain
NCT04199091
Conditions: Low Back Pain, Mechanical; Complementary Therapies; Progressive Muscle Relaxation
Interventions: Procedure: Craniosacral Therapy (CST) self-help techniques; Procedure: Progressive Muscle Relaxation (PMR)
Sponsor: Universität Duisburg-Essen
Not yet recruiting
Clinical Trial to Explore Papilocare Gel Efficacy to Repair of the Cervico-vaginal Mucosa With HPV High Risk Lesions.
NCT04199078
Conditions: Human Papilloma Virus; Human Papilloma Virus Infection; Cervix Lesion
Intervention: Device: Papilocare vaginal gel
Sponsors: Procare Health Iberia S.L.; Adknoma Health Research
Recruiting
Impact of Good Practice Guidelines on Evidence-based Practice and Nurses' Work Environment
NCT04199065
Conditions: Nurses' Work Environment; Committed Centers With Excellence in Care (CCEC®) Program; Nurses' Evidence-based-practice Attitudes; Nurse Physician Relations; Practice Nurse's Scope; Professional Stress
Intervention: Other: Good Practice Guidelines implementation
Sponsors: Parc de Salut Mar; IMIM, Institut Hospital del Mar d'Investigacions Mèdiques; COIB, Col·legi d'Infermers i infermeres de Barcelona; Department of Health, Generalitat de Catalunya (PERIS)
Active, not recruiting
LinkPositively: A Technology-Delivered Peer Navigation and Social Networking Intervention to Improve HIV Care
NCT04199052
Condition: HIV/AIDS
Intervention: Behavioral: LinkPositively
Sponsors: University of California, San Diego; San Diego State University; National Institute of Mental Health (NIMH)
Not yet recruiting
Effects of Endotracheal Tube Fixation Methods on Hemodynamic Parameters During Endotracheal Suction
NCT04199039
Condition: Cardiac Surgery
Intervention: Other: Effect on Endotracheal Tube Fixation Methods on Hemodynamic Parameters During Endotracheal Suction
Sponsor: Mersin University
Completed
Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma
NCT04199026
Conditions: Metastatic Sarcoma; Recurrent Sarcoma; Resectable Sarcoma
Interventions: Drug: Doxorubicin; Drug: Doxorubicin Hydrochloride; Device: Drug Delivery Microdevice; Drug: Everolimus; Biological: Ganitumab; Drug: Ifosfamide; Drug: Irinotecan; Drug: Pazopanib; Drug: Polyethylene Glycol; Drug: Temozolomide; Drug: Temsirolimus; Procedure: Therapeutic Conventional Surgery; Drug: Vincristine
Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Not yet recruiting
Comparison of Ropivacaine With or Without Fentanyl in Spinal Anaesthesia for Lower Limb Surgeries
NCT04199013
Conditions: Leg Injury; Arthroplasty, Replacement, Knee
Interventions: Drug: Ropivacaine 0.75% Injectable Solution; Drug: Fentanyl Citrate
Sponsor: Tribhuvan University Teaching Hospital, Institute Of Medicine.
Not yet recruiting
Clinical and Basic Investigations Into Congenital Disorders of Glycosylation
NCT04199000
Condition: Congenital Disorders of Glycosylation
Intervention:
Sponsors: Mayo Clinic; National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting
Dietary Monosaccharide Supplementation in Patients With Congenital Disorders of Glycosylation
NCT04198987
Condition: Congenital Disorder of Glycosylation
Intervention:
Sponsor: Mayo Clinic
Recruiting
The Canadian Underage Substance Use Prevention Trial
NCT04198974
Conditions: Substance Use Disorders; Adolescent Behavior; Adolescent Development
Interventions: Behavioral: PreVenture Training (PTtT); Behavioral: PreVenture Training+Implementation Facilitation
Sponsors: St. Justine's Hospital; University of British Columbia; Center for Addiction and Mental Health; Dalhousie University; Canadian Institutes of Health Research (CIHR)
Recruiting
Electronic Intervention to Chronic Opioid Therapy
NCT04198961
Condition: Chronic Opioid Therapy
Intervention: Other: opioid prescribing
Sponsor: Stanford University
Not yet recruiting
Interaction Between Omeprazole and Gliclazide in CYP2C19 Normal/ Ultrarapid Metabolisers
NCT04198948
Condition: Diabetes Mellitus, Type 2
Interventions: Drug: Omeprazole; Drug: Placebo oral tablet; Drug: Gliclazide
Sponsors: University of Sarajevo; General Hospital Prim. Dr. Abdulah Nakas; University of Dundee
Completed
Evaluating a Digital Diabetes Education Program
NCT04198935
Condition: Diabetes Mellitus, Type 2
Intervention: Device: Span Health Mobile Application
Sponsor: Adam Bataineh
Not yet recruiting
Acalabrutinib for the Treatment of Chronic Graft Versus Host Disease
NCT04198922
Condition: Recurrent Moderate-Severe Chronic Graft Versus Host Disease
Interventions: Drug: Acalabrutinib; Other: Questionnaire Administration
Sponsors: Fred Hutchinson Cancer Research Center; National Cancer Institute (NCI); AstraZeneca
Not yet recruiting
Optimization of a Non-invasive Electrophysiological Method for Studying the Functionality of Auditory Nerve Fibers
NCT04198909
Conditions: Healthy Volunteer; Without Hearing Disorders
Intervention: Diagnostic Test: Electrocochleography, electrophysiology thet for analyse the wave I generated by the auditory pathways
Sponsors: University Hospital, Clermont-Ferrand; Laboratory of Neurosensory Biophysics - UMR INSERM 1107.; Foundation of Gueules Cassées; Region of Auvergne-Rhône-Alpes
Recruiting
The Sakakibara Health Integrative Profile of Atherosclerotic-Carcinogenesis Hypothesis (SHIP-AC)
NCT04198896
Conditions: Cancers; Atheroscleroses, Coronary; Atherosclerosis of Artery
Intervention: Other: incidece of cancers
Sponsor: Sakakibara Heart Institute
Completed
SINGaporean Program Performed With an eXPANsion Medical Device (SingXpand)
NCT04198883
Condition: Heart Attack
Intervention: Combination Product: Protheracytes
Sponsor: CellProthera
Active, not recruiting
MitraClip REPAIR MR Study
NCT04198870
Condition: Mitral Valve Regurgitation
Interventions: Device: MitraClip™ device implantation; Procedure: Mitral Valve Repair Surgery
Sponsor: Abbott Medical Devices
Not yet recruiting
Development and Testing of a Mobile Health Application for Management of Gestational Diabetes
NCT04198857
Conditions: Diabetes, Gestational; Telemedicine
Intervention: Behavioral: Develop a mobile app that supports self- management and treatment for Nepalese GDM patients
Sponsors: Rutgers, The State University of New Jersey; Nepal Health Research Council; University of Connecticut; John E. Fogarty International Center (FIC); Dhulikhel Hospital
Not yet recruiting
The Effectiveness and Safety of Apixaban in NVAF Patients With History of Osteoporosis and/or Fracture: A Nation-wide Population Based Study
NCT04198844
Condition: Atrial Fibrillation
Interventions: Drug: warfarin; Drug: apixaban
Sponsor: Pfizer
Active, not recruiting
Effect of Acupuncture on Quiescent Crohn's Disease
NCT04198831
Conditions: Inflammatory Bowel Diseases; Crohn Disease
Interventions: Other: acupuncture; Other: Sham acupuncture
Sponsors: Shanghai Institute of Acupuncture, Moxibustion and Meridian; Fudan University; Shanghai University of Traditional Chinese Medicine; Ruijin Hospital; Indiana University School of Medicine
Recruiting
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of HH2710 in Patient With Advanced Tumors
NCT04198818
Conditions: Advanced Tumors; Melanoma; Non-Small-Cell Lung Cancer; Erdheim-Chester Disease; Other RAS/RAF/MEK/ERK Mutated Tumors
Intervention: Drug: HH2710
Sponsor: ShangHai HaiHe Pharmaceutical
Not yet recruiting
Vitamin E and DHA-EE on NAFLD - Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Clinical Trial (PUVENAFLD)
NCT04198805
Conditions: Non-Alcoholic Fatty Liver Disease; Non-Alcoholic Fatty Liver; Non-Alcoholic Steatohepatitis
Interventions: Dietary Supplement: Vitamin E [(all-rac)-α-tocopheryl acetate]; Dietary Supplement: Omega-3 fatty acid (DHA EE); Combination Product: Omega-3 fatty acid (DHA EE) & Vitamin E [(all-rac)-α-tocopheryl acetate]; Other: Placebo
Sponsors: Naga P. Chalasani; DSM Nutritional Products, Inc.
Recruiting
Predictors for Survival and Good Neurological Outcome in E-CPR and Non CPR Treated Patients
NCT04198792
Conditions: Cardiac Arrest; Extracorporeal Membrane Oxygenation; Hypoxia-Ischemia, Brain
Intervention: Other: No intervention
Sponsor: Sahlgrenska University Hospital, Sweden
Recruiting
Interest of the Smartphone Application "MonCœur" in the Follow-up of Patients With Heart Failure
NCT04198779
Conditions: Heart Failure; Heart Decompensation
Intervention: Device: APPLI
Sponsor: French Cardiology Society
Not yet recruiting
Study of INBRX-106 in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
NCT04198766
Conditions: Solid Tumor; Non-Small Cell Lung Cancer; Melanoma; Head and Neck Cancer; Gastric Cancer; Renal Cell Carcinoma; Urothelial Carcinoma
Interventions: Drug: INBRX-106 - Hexavalent OX40 agonist antibody; Drug: Pembrolizumab
Sponsor: Inhibrx, Inc.
Recruiting
Skin Characteristics of Parents of Food Allergic Pediatric Patients
NCT04198753
Condition: Food Allergy in Children
Interventions: Diagnostic Test: Skin tape stripping; Device: Skin barrier assessment; Diagnostic Test: Blood draw
Sponsor: National Jewish Health
Not yet recruiting
Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface
NCT04198740
Conditions: Dry Eye Syndrome; Infectious Keratoconjunctivitis; Mucous Membrane Pemphigoid; Allergic Conjunctivitis
Intervention: Diagnostic Test: Tear sample collection via Schirmer strip and subsequent analysis by mass spectrometry
Sponsors: Centre hospitalier de l'Université de Montréal (CHUM); Université du Québec a Montréal
Not yet recruiting
Study of the Impact of DPD Activity on the Efficacy of Capecitabine
NCT04198727
Condition: Breast Neoplasm Malignant Female
Interventions: Other: DPD activity assessment; Drug: Capecitabine
Sponsors: Centre Antoine Lacassagne; Cerbaliance
Not yet recruiting
Pudendal Nerve Block in Vaginal Surgery
NCT04198714
Conditions: Nerve Block; Pain, Postoperative; Pelvic Floor Disorders; Pelvic Organ Prolapse; Pudendal Neuralgia; Surgery
Intervention: Procedure: Pudendal block
Sponsor: MetroHealth Medical Center
Recruiting
Pulsed Field Ablation to Irreversibly Electroporate Tissue and Treat AF
NCT04198701
Condition: Atrial Fibrillation
Intervention: Device: Medtronic Pulsed Field Ablation (PFA) System
Sponsor: Medtronic Cardiac Rhythm and Heart Failure
Not yet recruiting
Effectiveness of Intensive Smoking Cessation Interventions in Patients With Cancer
NCT04198688
Conditions: Tobacco Smoking; Cancer; Tobacco Cessation
Intervention: Behavioral: Intensive Smoking Cessation Intervention
Sponsors: Bispebjerg Hospital; Rigshospitalet, Denmark; Aarhus University Hospital Skejby; Danish Cancer Society
Completed
Effects of Preventive Physiotherapy Practices on Posture and Work-Related Functions in Office Workers
NCT04198675
Conditions: Work-related Musculoskeletal Disorders; Office Workers
Interventions: Behavioral: Supervised EMG Biofeedback Exercise Training Group; Behavioral: Home-Based Exercise Training Group; Behavioral: Posture Training/Ergonomic Regulations Group
Sponsors: Marmara University; Hacettepe University
Active, not recruiting
Rib Fracture Analgesia Using Cryoanalgesia
NCT04198662
Condition: Traumatic Rib Fracture(s)
Interventions: Device: Cryoneurolysis with a Painblocker (Epimed International, Farmers Branch, Texas); Drug: Intercostal nerve block ropivacaine with epinephrine
Sponsors: University of California, San Diego; University of Florida; Epimed International
Recruiting
Effect of Azithromycin on Failure Proportion of Severe Periodontitis Non-surgical Treatment
NCT04198649
Condition: Severe Chronic Periodontitis
Interventions: Drug: Non-surgical periodontal treatment and azithromycin treatment; Other: Non-surgical periodontal treatment and placebo treatment
Sponsor: University Hospital, Strasbourg, France
Not yet recruiting
A Study to Evaluate LY01011 and Xgeva® in Healthy Adults
NCT04198636
Condition: Healthy Adults
Interventions: Drug: LY01011; Drug: Xgeva 120 MG in 1.7 ML Injection
Sponsors: Luye Pharma Group Ltd.; Shang Dong Boan Biotechnology Co., Ltd (Co-sponsor)
Not yet recruiting
Efficacy of Montelukast in Reducing the Incidence and Severity of Monoclonal Antibodies Associated Infusion Reactions
NCT04198623
Conditions: Infusion Reaction; Monoclonal Antibody
Intervention: Drug: Montelukast 10 Mg Oral Tablet
Sponsor: University of California, San Francisco
Not yet recruiting
Evaluation and Correlation of Serum Fetuin-A Levels in Periodontal Health and Disease: A Clinico-biochemical Study
NCT04198610
Condition: Gingivitis and Periodontal Diseases
Intervention: Procedure: Non surgical periodontal therapy
Sponsor: Krishnadevaraya College of Dental Sciences & Hospital
Completed
Exploring Two Treatments for Misophonia
NCT04198597
Condition: Misophonia
Interventions: Behavioral: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders; Behavioral: Process-based Cognitive Behavioral Therapy
Sponsor: Duke University
Not yet recruiting
Study of Telemedicine Stress Management and Lifestyle Group Intervention for HCV Patients
NCT04198584
Condition: Chronic Hepatitis C
Intervention: Behavioral: VC-CBCS
Sponsors: University of North Carolina, Chapel Hill; Duke University; National Institute of Nursing Research (NINR)
Not yet recruiting
Retrospective Chart Review Study to Assess Characteristics, Treatment Outcomes and Resource Use of Adults Hospitalized for CAP and CSSTi Treated With Zinforo in Multiple Countries
NCT04198571
Conditions: Community Acquired Pneumonia; Complicated Skin and Soft Tissue Infection
Intervention: Drug: Zinforo (ceftaroline fosamil)
Sponsor: Pfizer
Not yet recruiting
A Study of the Safety, Tolerability and Pharmacokinetics of MEDI0618 in Healthy Volunteers
NCT04198558
Condition: Chronic Pain
Interventions: Drug: MEDI0618; Drug: Placebo
Sponsor: AstraZeneca
Recruiting
Ethnic Differences in Iron Absorption (FeGenes)
NCT04198545
Conditions: Anemia, Iron Deficiency; Iron Overload
Intervention:
Sponsors: Cornell University; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Office of Dietary Supplements (ODS)
Recruiting
Contrast Bath and Sympathetic Skin Response
NCT04198532
Conditions: Stroke; Sympathetic Disorder
Intervention: Other: Contrast bath
Sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Completed
Effects of Weight Loss on Vascular Function in Obese Subjects
NCT04198519
Condition: Obesity
Intervention: Other: Weight Loss
Sponsors: Mario Fritsch Neves; Rio de Janeiro State Research Supporting Foundation (FAPERJ); Conselho Nacional de Desenvolvimento Científico e Tecnológico
Recruiting
Viral Load Guided Immunosuppression After Lung Transplantation
NCT04198506
Condition: Transplantation Lung
Interventions: Other: Tailored tacrolimus dosing; Other: Conventional tacrolimus dosing
Sponsor: Philipps University Marburg Medical Center
Not yet recruiting
Effect of CPAP Treatment in Cognition in Adults With DS and OSA
NCT04198493
Condition: Obstructive Sleep Apnea
Interventions: Device: CPAP; Other: CONSERVATIVE TREATMENT FOR OSA
Sponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Not yet recruiting
A Clinical Trial to Assess the Efficacy and Safety of JMT103 in Patients With Refractory HCM
NCT04198480
Condition: Hypercalcemia of Malignancy
Intervention: Drug: JMT103
Sponsors: Shanghai JMT-Bio Inc.; CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Not yet recruiting
To Evaluate the Optimum Dose of Platelet Rich Plasma in Knee Osteoarthritis and Compare Efficacy With Hyaluronic Acid
NCT04198467
Condition: Knee Osteoarthritis
Interventions: Biological: Platelet rich plasma; Drug: Hyaluronic Acid
Sponsor: Dr. Himanshu Bansal Foundation
Completed
Compression and CO2 Laser for Leg Wounds
NCT04198454
Condition: Wound Healing
Interventions: Other: Compression bandages; Other: Standard wound dressings; Device: Fractional ablative carbon dioxide laser
Sponsor: Northwestern University
Not yet recruiting
The Omeza Protocol for Chronic Ulcers
NCT04198441
Conditions: Venous Leg Ulcer; Diabetic Foot Ulcer
Intervention: Device: Wound dressing
Sponsor: Omeza, LLC
Not yet recruiting
Clinical Decision Support for Opioid Use Disorders in Medical Settings (COMPUTE 2.0)
NCT04198428
Condition: Opioid-use Disorder
Intervention: Other: Opioid Wizard
Sponsors: HealthPartners Institute; National Institute on Drug Abuse (NIDA); The Emmes Company, LLC; Hennepin Healthcare Research Institute.
Recruiting
A Study of the Safety and Efficacy of Venetoclax in Japanese Participants With Relapsed and Refractory Chronic Lymphocytic Leukemia (Including Small Lymphocytic Leukemia)
NCT04198415
Conditions: Cancer; Chronic Lymphocytic Leukemia (CLL); Small Lymphocytic Leukemia (SLL)
Intervention:
Sponsor: AbbVie
Not yet recruiting
Microbiotic Analysis in Digestive Endocrine Tumors
NCT04198402
Conditions: Digestive Neuroendocrine Tumor; Fecal Microbiota; Bacterial Signature
Intervention: Biological: Biological sampling
Sponsor: Assistance Publique - Hôpitaux de Paris
Not yet recruiting
Retrospective Clinical and Functional Evaluation of Patients Undergoing Knee Replacement With Small Implants
NCT04198389
Condition: KNEE REPLACEMENT
Intervention: Procedure: PARTIAL KNEE REPLACEMENT
Sponsor: Istituto Ortopedico Galeazzi
Active, not recruiting
The Laterally Closed Tunnel Versus Modified Coronally Advanced Tunnel With Subepithelial Connective Tissue Graft for Treatment of Deep Isolated Mandibular Anterior Gingival Recession Defects
NCT04198376
Condition: Gingival Recession, Localized
Interventions: Procedure: Group A The Laterally Closed Tunnel Technique with SCTG; Procedure: Group B Modified Coronally Advanced Tunnel Technique with SCTG.
Sponsor: Krishnadevaraya College of Dental Sciences & Hospital
Enrolling by invitation
A Study to Evaluate the Efficacy and Safety of Bismuth-Containing Quadruple Therapy With Oral Vonoprazan (TAK-438) 20 mg Compared to Esomeprazole 20 mg Twice Daily in Paticipants With Helicobacter Pylori Infection
NCT04198363
Condition: Helicobacter Pylori
Interventions: Drug: Vonoprazan; Drug: Amoxicillin; Drug: Clarithromycin; Drug: Bismuth Potassium citrate; Drug: Esomeprazole
Sponsor: Takeda
Not yet recruiting
Pancreatic Islet Transplantation to the Anterior Chamber of the Eye
NCT04198350
Conditions: Type 1 Diabetes; Visual Impairment
Intervention: Procedure: Islet implantation
Sponsor: Imperial College London
Not yet recruiting
Endoscopic Full Thickness Resection for Gastric GIST
NCT04198337
Condition: Gastric GIST
Intervention: Procedure: Endoscopic Full Thickness Resection
Sponsor: Chinese University of Hong Kong
Recruiting
Isthmocele After Endometrial and Non-endometrial Suturing in Cesarean Section
NCT04198324
Conditions: Cesarean Section; Dehiscence; Cesarean Wound; Dehiscence
Interventions: Procedure: Closure of the uterus with endometrium at the time of cesarean; Procedure: Closure of the uterus without endometrium at the time of cesarean
Sponsor: Kocaeli University
Not yet recruiting
The Impact of CBT for Insomnia on Alcohol Treatment Outcomes
NCT04198311
Conditions: Insomnia; Alcohol Use Disorder
Interventions: Behavioral: CBT-I; Behavioral: Sleep Hygiene
Sponsor: University of Missouri-Columbia
Not yet recruiting
Prospective Clinical Trial of Three Apical Sealing Materials
NCT04198298
Condition: Periapical Abscess
Interventions: Drug: EndoSequence; Drug: ProRoot MTA; Drug: Biodentine
Sponsor: University of the Pacific
Completed
Post-Operative Voiding After Gynecological Surgery Trial
NCT04198285
Conditions: Urinary Retention; Postoperative Complications; Surgery
Intervention: Procedure: Retrograde bladder filling
Sponsor: Women's College Hospital
Not yet recruiting
Impact Evaluation of CyberRwanda
NCT04198272
Conditions: Pregnancy in Adolescence; Adolescent Health; Health Services Accessibility
Intervention: Behavioral: CyberRwanda
Sponsors: University of California, Berkeley; Youth Development Labs; Society for Family Health, Rwanda
Not yet recruiting
Interventional Devascularization Plus HVPG‐Guided Carvedilol Therapy vs TIPS
NCT04198259
Conditions: Gastric Varices Bleeding; Liver Cirrhoses
Interventions: Procedure: interventional devascularization; Procedure: TIPS
Sponsor: Fourth Military Medical University
Not yet recruiting
Chinese ET Registry (CETR)
NCT04198246
Condition: Essential Tremor
Intervention:
Sponsor: Xiangya Hospital of Central South University
Recruiting
Impact of Placement of a Diazepam Suppository on Early Postoperative Pain Following Pelvic Reconstructive Surgery
NCT04198233
Condition: Postoperative Pain
Interventions: Drug: Diazepam; Drug: Placebos
Sponsor: TriHealth Inc.
Not yet recruiting
BIO|STREAM.ICM Obesity
NCT04198220
Conditions: Tachycardia Atrial; Atrial Fibrillation; Syncope; Bradycardia; Cryptogenic Stroke
Intervention:
Sponsor: Biotronik SE & Co. KG
Not yet recruiting
The Effectiveness and Safety of Vagus Nerve Stimulation for TRE
NCT04198207
Conditions: Tuberous Sclerosis Complex; Epilepsy
Intervention:
Sponsors: Beijing Children's Hospital; Beijing Tiantan Hospital; First Hospital of Jilin University; Xuanwu Hospital, Beijing; Sanbo Brain Hospital Capital Medical University; Peking University First Hospital; China-Japan Friendship Hospital; Chinese PLA General Hospital; Fourth Medical Center of PLA General Hospital; Capital Institute of Pediatrics, China; The Second Hospital of Hebei Medical University; Xijing Hospital; First Affiliated Hospital Xi'an Jiaotong University; Children's Hospital of Fudan University; RenJi Hospital; Jining Medical University; Xiamen Humanity Hospital; Xiangya Hospital of Central South University; Wuhan Medical Care Center for Women and Children; Guangdong 999 Brain Hospital; Shenzhen Children's Hospital; Xinqiao Hospital, Army Medical University; West China Hospital
Not yet recruiting
Apple Heart & Movement Study
NCT04198194
Condition: Prevention
Intervention: Diagnostic Test: Predictors of events
Sponsors: Brigham and Women's Hospital; Apple Inc.; American Heart Association
Recruiting
The Effectiveness and Safety of Resective Epilepsy Surgery for TRE
NCT04198181
Conditions: Tuberous Sclerosis Complex; Epilepsy
Intervention:
Sponsors: Beijing Children's Hospital; Beijing Tiantan Hospital; First Hospital of Jilin University; Xuanwu Hospital, Beijing; Sanbo Brain Hospital Capital Medical University; Peking University First Hospital; China-Japan Friendship Hospital; Chinese PLA General Hospital; Fourth Medical Center of PLA General Hospital; Capital Institute of Pediatrics, China; The Second Hospital of Hebei Medical University; Xijing Hospital; First Affiliated Hospital Xi'an Jiaotong University; Children's Hospital of Fudan University; RenJi Hospital; Jining Medical University; Xiamen Humanity Hospital; Xiangya Hospital of Central South University; Wuhan Medical Care Center for Women and Children; Guangdong 999 Brain Hospital; Shenzhen Children's Hospital; Xinqiao Hospital, Army Medical University; West China Hospital
Not yet recruiting
The Predictive Performance of Renal Ultrasound on Changes in Renal Clearance
NCT04198168
Conditions: Acute Kidney Injury; Hypoperfusion; Fluid Overload
Intervention: Drug: IV crystalloid fluid bolus
Sponsor: Aarhus University Hospital
Recruiting
Renal Denervation Using Stereotactic Radiotherapy System for the Treatment of Refractory Hypertension
NCT04198155
Condition: Hypertension
Intervention: Radiation: stereotactic body radiotherapy (SBRT)
Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Not yet recruiting
Psychiatric Inpatient Nightmare Treatment
NCT04198142
Conditions: Nightmare; Psychiatric Disorder
Interventions: Behavioral: Imagery Rehearsal Therapy; Behavioral: Treatment as Usual with dream diaries
Sponsors: University of Zurich; Swiss National Science Foundation; Psychiatric University Hospital, Zurich
Recruiting
The Evaluation of Postoperative Antibiotics in Non-Infected Mandible Fractures
NCT04198129
Conditions: Jaw Fractures; Infection
Interventions: Drug: Antibiotic treatment (Unasyn or Clindamycin); Drug: Antibiotic treatment (Augmentin or Clindamycin); Other: Control Group
Sponsor: The University of Texas Health Science Center, Houston
Not yet recruiting
Combining Varenicline and Guanfacine for Smoking Cessation
NCT04198116
Condition: Smoking Cessation
Interventions: Drug: Varenicline; Drug: Varenicline + Guanfacine ER
Sponsors: Yale University; National Institute on Drug Abuse (NIDA)
Not yet recruiting
Transperineal Laser Ablation for Percutaneous Treatment of Benign Prostatic Hyperplasia
NCT04198103
Conditions: BPH; Lower Urinary Tract Symptoms
Intervention: Device: Transperineal Focal Laser Ablation (TPLA)
Sponsors: University of Rome Tor Vergata; Ospedale Regina Apostolorum; European Institute of Oncology
Active, not recruiting
Sexual & Gender Minority Competency in Oncology
NCT04198090
Condition: Neoplasms
Intervention: Behavioral: SGM Competency Training Program
Sponsor: University of Rochester
Not yet recruiting
Conservative Versus Conventional Oxygen Administration in Critically Ill Patients
NCT04198077
Conditions: Critical Illness; Respiration, Artificial; Hyperoxia; Hyperoxemia
Intervention: Drug: Oxygen
Sponsor: University of Modena and Reggio Emilia
Recruiting
Pain Management for Cystoscopy: A Prospective Randomized Study Focused on Understanding the Role of the "Bag Squeeze" to Manage Pain for Patients Undergoing Cystoscopy
NCT04198064
Condition: Pain, Procedural
Interventions: Procedure: Bag Squeeze; Procedure: No Bag Squeeze
Sponsor: University Health Network, Toronto
Completed
The Clinical Study of Adjuvant Chemotherapy on Intestinal and Urethral Flora in Patients With Gastric and Colon Cancer
NCT04198051
Conditions: Gastric Cancer; Colon Cancer
Intervention: Drug: adjuvant chemotherapy
Sponsor: The First Affiliated Hospital of Dalian Medical University
Recruiting
Family-Centered Songwriting in Pediatric Palliative Care
NCT04198038
Condition: Cognitive Impairment
Intervention: Behavioral: Songwriting with licensed music therapist
Sponsor: Vanderbilt University
Not yet recruiting
Psoas Density in Colorectal Cancer
NCT04198025
Condition: Cancer of Colon
Intervention:
Sponsor: University of Nottingham
Not yet recruiting
An Open Label Study to Allow Patients Continuous Use of the HemoCare™ Hemodialysis System
NCT04198012
Condition: End Stage Renal Disease
Intervention: Device: HemoCare™ Hemodialysis System
Sponsors: Deka Research and Development; CVS Kidney Care LLC.
Not yet recruiting
A Study to Determine Safety and Tolerability of GMI-1359 in Subjects With HR+ Metastatic Breast Cancer
NCT04197999
Conditions: HR+ Metastatic Breast Cancer; Breast Cancer; Breast Cancer Metastatic
Intervention: Drug: GMI-1359
Sponsor: GlycoMimetics Incorporated
Recruiting
Study of Oral Infigratinib for the Adjuvant Treatment of Subjects With Invasive Urothelial Carcinoma With Susceptible FGFR3 Genetic Alterations
NCT04197986
Conditions: Upper Tract Urothelial Carcinomas; Urothelial Bladder Cancer
Interventions: Drug: Infigratinib; Drug: Placebo
Sponsor: QED Therapeutics, Inc.
Not yet recruiting
Association Between Self-reported Web-based SCCAI and Health-related Quality of Life Index in UC Patients
NCT04197973
Conditions: Quality of Life; Ulcerative Colitis
Intervention:
Sponsors: YooJin Lee; Inje University; Gangnam Severance Hospital; Jeju National University Hospital; Soonchunhyang University Hospital
Not yet recruiting
Microwave Ablation and Surgical Resection for Micropapillary Thyroid Carcinoma
NCT04197960
Condition: Papillary Thyroid Carcinoma
Interventions: Procedure: Microwave ablation; Procedure: Surgical resection
Sponsor: Chinese PLA General Hospital
Not yet recruiting
Selectively Modulating Pathophysiological Biomaker to Improve Freezing of Gait in Parkinson' s Disease by Adaptive Subthalamic Stimulation
NCT04197947
Conditions: Freezing of Gait; Parkinson Disease
Intervention: Device: Neuro Omega
Sponsor: Chang Gung Memorial Hospital
Recruiting
WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases
NCT04197934
Conditions: Anaplastic Astrocytoma, IDH-Wildtype; Glioblastoma, IDH-Wildtype; Lung Non-Small Cell Carcinoma; Metastatic Malignant Neoplasm in the Central Nervous System; Metastatic Malignant Neoplasm in the Leptomeninges
Interventions: Drug: EGFR/EGFRvIII Inhibitor WSD0922-FU; Procedure: Therapeutic Conventional Surgery
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Not yet recruiting
Exablate for LIFU Neuromodulation in Patients With Opioid Use Disorder (OUD)
NCT04197921
Condition: Opioid-use Disorder
Intervention: Device: Exablate Model 4000 Type 2.0/2.1
Sponsor: InSightec
Recruiting
EUS-guided Gallbladder Drainage Instead of Laparoscopic Cholecystectomy for Acute Cholecystitis. A Feasibility Study.
NCT04197908
Condition: Acute Cholecystitis
Intervention: Device: EUS-guided gallbladder drainage (EGBD)
Sponsor: Chinese University of Hong Kong
Not yet recruiting
Clinical and Radiographic Evaluation of Advanced Platelet Rich Fibrin in the Preservation of Alveolar Ridge Following Atraumatic Tooth Extraction
NCT04197895
Condition: Socket Preservation
Interventions: Procedure: Socket preservation with APRF; Procedure: natural healing
Sponsor: Nahed Gamal Saleh Abdelaal
Not yet recruiting
Clinical Study to Evaluate OrienX010 in Combination With Treprizumab Injection as Neoadjuvant Treatment in Melanoma
NCT04197882
Condition: Melanoma (Skin)
Intervention: Biological: OrienX010 Combination with Treprizumab injection
Sponsor: Beijing Cancer Hospital
Recruiting
Does a Preoperative Bowel Regimen Change Time to First Bowel Movement After Robotic Sacral Colpopexy
NCT04197869
Conditions: Constipation; Post-Op Complication
Intervention: Drug: Polyethylene Glycol Powder
Sponsor: Northwell Health
Recruiting
Direct Information to At-risk Relatives
NCT04197856
Conditions: Familial Breast Cancer; Familial Colorectal Cancer; Hereditary Breast and Ovarian Cancer Syndrome; Hereditary Breast Cancer; Lynch Syndrome
Interventions: Other: Standard care encouraging family-mediated disclosure of hereditary cancer risk; Other: Offer of health-care assisted disclosure by sending direct letters to at-risk relatives
Sponsors: Umeå University; Göteborg University; Lund University; Karolinska Institutet
Not yet recruiting
Navicam as a Triage Tool in the Management of Patients With Acute Upper Gastrointestinal Bleeding
NCT04197843
Condition: GastroIntestinal Bleeding
Intervention: Device: NaviCam (ANKON)
Sponsor: Chinese University of Hong Kong
Not yet recruiting
Evaluation of Acute Post-thrombectomy Complications for Stroke
NCT04197830
Conditions: Stroke, Complication; Stroke, Acute; Stroke Hemorrhagic
Intervention: Procedure: Thrombectomy for stroke
Sponsor: University of Liege
Not yet recruiting
A Single Dose Escalation Study of PCSK9 Inhibitor (JS002) in Health Subjects
NCT04197817
Condition: Hypercholesterolemia
Interventions: Drug: JS002; Drug: Placebo
Sponsor: Shanghai Junshi Bioscience Co., Ltd.
Completed
Do Mirror Neurons Play a Role in Tourette Syndrome Physiopathology? A Pilot Study.
NCT04197804
Condition: Tourette Syndrome
Intervention: Other: Routine tests perform
Sponsor: Istituto Ortopedico Galeazzi
Completed
Effect of Core Stabilization Exercises and Neuromuscular Electrical Stimulation in Patients With Idiopathic Pulmonary Fibrosis
NCT04197791
Condition: Idiopathic Pulmonary Fibrosis
Interventions: Device: Neuromuscular Electrical Stimulation; Other: Core Stabilization Exercises
Sponsor: Istanbul University-Cerrahpasa
Active, not recruiting
Food Effect Study of DDO-3055 Tablets in Healthy Subjects
NCT04197778
Condition: Anemia in Chronic Kidney Disease
Intervention: Drug: DDO-3055 tablet
Sponsor: Jiangsu HengRui Medicine Co., Ltd.
Not yet recruiting
acTBS Treatment for Inpatient Subjects With Suicidality
NCT04197765
Condition: Suicidality
Intervention: Device: accelerated Thetaburst stimulation
Sponsor: University of California, Los Angeles
Not yet recruiting
Regional Anesthesia and Analgesia Techniques in Obese Patients
NCT04197752
Conditions: Obesity; Regional Anesthesia
Intervention: Other: Regional anesthesia/analgesia techniques
Sponsor: Istanbul University
Recruiting
Fixed-dose Amikacin for Elderly UTI
NCT04197739
Conditions: Urinary Tract Infections; Elderly Infection
Intervention: Drug: Amikacin
Sponsor: Rabin Medical Center
Not yet recruiting
Glycaemic Response to High REsistant STarch Bread
NCT04197726
Condition: Blood Glucose Response
Interventions: Other: sbeIIa/b white bread; Other: Control white bread
Sponsors: Quadram Institute Bioscience; Norfolk and Norwich University Hospitals NHS Foundation Trust
Not yet recruiting
Testing the Sequential Combination of the Anti-cancer Drugs Olaparib Followed by Adavosertib (AZD1775) in Patients With Advanced Solid Tumors With Selected Mutations and PARP Resistance, STAR Study
NCT04197713
Conditions: Advanced Malignant Solid Neoplasm; Metastatic Malignant Solid Neoplasm; Refractory Malignant Solid Neoplasm; Unresectable Malignant Solid Neoplasm
Interventions: Drug: Adavosertib; Drug: Olaparib
Sponsor: National Cancer Institute (NCI)
Not yet recruiting
The PRESSURE CABG Cardiac Surgery Trial
NCT04197700
Conditions: Coronary Artery Bypass Grafting; Hypotension
Intervention: Other: Target MAP Management
Sponsors: University of Alberta; Canadian VIGOUR Centre
Not yet recruiting
TPIV100 and Sargramostim for the Treatment of HER2 Positive, Stage II-III Breast Cancer in Patients With Residual Disease After Chemotherapy and Surgery
NCT04197687
Conditions: Breast Adenocarcinoma; Stage II Breast Cancer AJCC v6 and v7; Stage IIA Breast Cancer AJCC v6 and v7; Stage IIB Breast Cancer AJCC v6 and v7; Stage III Breast Cancer AJCC v7; Stage IIIA Breast Cancer AJCC v7; Stage IIIB Breast Cancer AJCC v7; Stage IIIC Breast Cancer AJCC v7
Interventions: Biological: Pertuzumab; Other: Placebo Administration; Biological: Sargramostim; Biological: Trastuzumab; Biological: Trastuzumab Emtansine; Biological: Vaccine Therapy
Sponsors: Mayo Clinic; National Cancer Institute (NCI)
Not yet recruiting
China Q Cohort Study
NCT04197674
Conditions: End Stage Renal Disease on Dialysis; Peritoneal Dialysis; Hemodialysis
Intervention: Other: Dialysis modality
Sponsor: Sun Yat-sen University
Not yet recruiting
Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Healthy Elderly Subjects
NCT04197661
Condition: Healthy Elderly Subjects
Intervention: Drug: HSK3486
Sponsors: Sichuan Haisco Pharmaceutical Group Co., Ltd.; First Hospital of Jilin University
Not yet recruiting
Effects of Exercise on Thoracic Aneurysms
NCT04197648
Condition: Aneurysms and Exercise
Intervention: Device: Exercise group
Sponsor: Paul Poirier
Not yet recruiting
Short-term Effects of Dapagliflozin on Peak VO2 in HFrEF
NCT04197635
Conditions: Heart Failure With Reduced Ejection Fraction; Type 2 Diabetes
Interventions: Diagnostic Test: Maximal functional capacity by cardiopulmonary exercise testing; Diagnostic Test: Echocardiography; Behavioral: Evaluation of quality of life health related; Diagnostic Test: Submáximal functional capacity assesment by 6 minutes walk test
Sponsor: Fundación para la Investigación del Hospital Clínico de Valencia
Recruiting
Generation of Biological Samples Positive to Hydrochlorothiazide for Anti-doping Control
NCT04197622
Condition: Healthy Volunteers
Intervention: Drug: Hydrochlorothiazide
Sponsor: Parc de Salut Mar
Completed
Static Muscular Stretching for Treatment of Peripheral Arterial Disease
NCT04197609
Condition: Peripheral Artery Disease
Intervention: Device: Dorsiflexion Splint
Sponsors: Mayo Clinic; Florida State University, College of Medicine
Not yet recruiting
Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)
NCT04197596
Conditions: Viral Infection; Primary Immune Deficiency Disorder
Intervention: Biological: BK CTL
Sponsors: New York Medical College; Children's Hospital of Philadelphia; Medical College of Wisconsin; Nationwide Children's Hospital
Not yet recruiting
DJUS Postmarket Registry
NCT04197583
Condition: Ureter Obstruction
Intervention: Device: Double-J Ureteral Stent
Sponsor: Boston Scientific Corporation
Not yet recruiting
OPIOID-FREE ANESTHESIA FOR OPEN CARDIAC SURGERY: A PROSPECTIVE RANDOMIZED CONTROLLED TRIAL
NCT04197570
Conditions: Opioid Use; Heart; Surgery, Heart, Functional Disturbance as Result; Anesthesia
Interventions: Drug: Opioid Anesthetics; Drug: Non Opioid Analgesics
Sponsors: Benaroya Research Institute; Virginia Mason Hospital/Medical Center
Not yet recruiting
Bone Age of Chinese Child (BACC)
NCT04197557
Condition: Bone Development
Intervention:
Sponsors: Beijing Jishuitan Hospital; National Institute for Nutrition and Health Chinese Center for Disease Control and Prevention; Beijing institute of child
Recruiting
Evaluation of the Implantation of the End-vascular Creation of the Arteriovenous Fistulas in Patients in the University Hospital of Araba. Pilot Study.
NCT04197544
Condition: Efficacy and Safety
Intervention: Procedure: endoFAVI
Sponsor: Fernando López Zárraga
Not yet recruiting
Postoperative Pain After the Use of Different Last Irrigation Method During Root Canal Treatment in Primary Teeth
NCT04197531
Condition: Post Operative Pain
Intervention: Other: Irrigation Method
Sponsor: TC Erciyes University
Completed
Evaluation the Neurocognitive Functions Among Children With Enlargement Adenoid and Tonsils, Before and After Tonsillectomy or Adenotonsillectomy
NCT04197518
Condition: Child Neurocognitive Function
Intervention: Diagnostic Test: neuro trax system and a neurology test.
Sponsor: Hillel Yaffe Medical Center
Not yet recruiting
Application of Forward-looking Infrared for the Identification and Evaluation of Fractures in the Acute Trauma Setting
NCT04197505
Condition: Acute Fracture
Intervention: Behavioral: FLIR E95 camera
Sponsor: NYU Langone Health
Not yet recruiting
Hypofractionated Stereotactic Radiotherapy With Anlotinib in Patients With Recurrent High-Grade Gliomas
NCT04197492
Condition: Malignant Glioma
Interventions: Radiation: Hypofractionated Stereotactic Radiotherapy; Drug: Anlotinib
Sponsor: Huashan Hospital
Not yet recruiting
A Study to Evaluate the Safety and Biomarkers of Resmetirom (MGL-3196) in Non Alcoholic Fatty Liver Disease (NAFLD) Patients
NCT04197479
Condition: Non-Alcoholic Fatty Liver Disease
Interventions: Drug: Placebo; Drug: Resmetirom
Sponsor: Madrigal Pharmaceuticals, Inc.
Recruiting
Comparison of Different Treatments for Overactive Bladder Syndrome
NCT04197466
Conditions: Overactive Bladder; Overactive Bladder Syndrome; Overactive Detrusor
Interventions: Other: Pelvic Floor Exercise Group; Other: Kinesio tape; Other: Electrical stimulation
Sponsor: Ankara Yildirim Beyazıt University
Recruiting
The Cardiovascular Multi-dimensional Observational Investigation of the Use of PCSK9 Inhibitors (cvMOBIUS)
NCT04197453
Condition: ASCVD
Intervention:
Sponsors: Amgen; Duke Clinical Research Institute
Recruiting
Characterization of Bovine Adrenal Medulla (BAM8-22) as a New Surrogate Model of Non-histaminergic Itch
NCT04197440
Conditions: BAM8-22; SPT Pricks
Interventions: Drug: BAM8-22 2mg/ml; Drug: BAM8-22 1mg/ml; Drug: BAM8-22 0.5 mg/ml; Drug: Placebo; Drug: BAM8-22 with 1 SPT; Drug: BAM8-22 with 5 SPT; Drug: BAM8-22 with 25 SPT; Drug: BAM8-22 with inactivate cowhage spicules
Sponsor: Aalborg University
Not yet recruiting
Determination of the Safety and Efficacy of a Novel Oral Rinse on Oral Health
NCT04197427
Conditions: Plaque; Gingivitis
Interventions: Device: Experimental Oral Rinse; Device: Placebo
Sponsor: You First Services
Not yet recruiting
Development of Urologic Registry for Personalized Medicine in Patients With Urological Malignancy by Analyzing Circulating Tumor DNA
NCT04197414
Conditions: Prostate Cancer; Renal Cell Cancer; Bladder Cancer; Ureter Cancer
Intervention:
Sponsor: Yonsei University
Recruiting
Screening & Health Education in Barbershops Centers for Hypertension
NCT04197401
Condition: Hypertension
Intervention:
Sponsors: Dacima Consulting; Société Tunisienne de Cardiologie & de Chirurgie Cardiovasculaire
Completed
Inspiratory Muscle Training in Pulmonary Arterial Hypertension
NCT04197388
Condition: Pulmonary Hypertension
Intervention: Device: Inspiratory muscle training device
Sponsor: Golden Jubilee National Hospital
Recruiting
Impact of Pre-cooling in Adolescent Tennis Athletes
NCT04197375
Condition: Risk of Heat Stress
Interventions: Behavioral: Thermal stress and performance using a pre-cooling protocol; Biological: Thermal stress and performance without a pre-cooling protocol
Sponsor: Petros Dinas
Completed
Everyday Activity Shoes: a Quantification of Impact Forces While Walking
NCT04197362
Condition: Impact Forces
Intervention: Other: Evaluation
Sponsor: Emory University
Not yet recruiting
Safety, Tolerability and Pharmacokinetics of ALD1910 in Healthy Men and Woman
NCT04197349
Condition: Migraine
Interventions: Biological: ALD1910; Biological: Sumatriptan
Sponsors: H. Lundbeck A/S; Alder Biopharmaceuticals, Inc.
Recruiting
Bariatric Embolization of Arteries With Imaging Visible Embolics (BEATLES)
NCT04197336
Conditions: Obesity; Morbid Obesity; Weight Loss
Interventions: Device: Bariatric Embolization of Arteries with imaging visible Embolics; Other: Control Arm
Sponsors: Johns Hopkins University; Biocompatibles UK Ltd
Not yet recruiting
Alprostadil Liposomes for Injection for Lower Extremity Arteriosclerosis Obliteran of Phase II Clinical Trial
NCT04197323
Condition: Peripheral Artery Disease
Intervention: Drug: Alprostadil liposomes for injection
Sponsor: CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Recruiting
Cabozantinib and Nivolumab for Carcinoid Tumors
NCT04197310
Conditions: Carcinoid Tumor; Carcinoid Tumor of GI System; Neuroendocrine Tumors
Interventions: Drug: Nivolumab; Drug: Cabozantinib
Sponsors: Dana-Farber Cancer Institute; Bristol-Myers Squibb; Exelixis
Not yet recruiting
Brain Imaging Biomarkers in Patients With Brain Metastasis
NCT04197297
Condition: Brain Metastases, Adult
Intervention: Diagnostic Test: CT and MRI Scans
Sponsor: University Health Network, Toronto
Not yet recruiting
Determination of the Effectiveness of Certain Physical Methods in the Treatment of Knee Osteoarthritis
NCT04197284
Condition: Osteoarthritis, Knee
Interventions: Device: Biofeedback, Myomed 632; Device: device for electrical stimulation, BTL 4000 Smart; Other: kinesitherapy
Sponsor: Clinical Hospital Centre Zagreb
Not yet recruiting
Management of Acutely Symptomatic Hernia
NCT04197271
Conditions: Hernia; Emergencies; Surgery--Complications
Interventions: Procedure: Emergency Hernia Repair; Other: Conservative management
Sponsor: Sheffield Teaching Hospitals NHS Foundation Trust
Not yet recruiting
Evaluation of the Impact of an Individual Peer Support Intervention for Stroke Patients When Returning Home: a Mixed Methods Pilot Study
NCT04197258
Condition: Stroke
Intervention: Other: Peer support
Sponsor: Hospices Civils de Lyon
Not yet recruiting
Efficacy of Saline Injection Therapy in Atrophic Acne Scars
NCT04197245
Conditions: Atrophic; Scars
Intervention: Drug: saline injection therapy in post-acne atrophic scars
Sponsor: Jinnah Postgraduate Medical Centre
Completed
Study on the Safety for the Newborn of the Use of Biologics During Pregnancy by Mothers Affected by Autoimmune Diseases
NCT04197232
Condition: Suspected Damage to Fetus From Biologic Agents
Intervention: Other: clinical evaluation
Sponsor: IRCCS San Raffaele
Recruiting
Pembrolizumab With Axitinib in Recurrent Endometrial Cancer
NCT04197219
Condition: Recurrent Endometrial Cancer
Interventions: Drug: Pembrolizumab; Drug: Axitinib
Sponsor: Haider Mahdi
Not yet recruiting
Ultrasound Guided Costotransverse Block for Breast Cancer Surgery
NCT04197206
Condition: Postoperative Pain
Intervention: Other: costotransverse block
Sponsor: Cigli Regional Training Hospital
Not yet recruiting
Monitoring Antioxidant/Redox Status at Concordia (MARS-C)
NCT04197193
Condition: Oxidative Stress
Intervention:
Sponsors: University of Southampton; European Space Agency
Not yet recruiting
Hybrid APC for Gastric Low Grade Intraepithelial Neoplasia
NCT04197180
Condition: Gastric Low Grade Intraepithelial Neoplasia
Intervention: Procedure: Hybrid Argon Plasma Coagulation
Sponsors: Chinese University of Hong Kong; Nanfang Hospital of Southern Medical University; Shenzhen Hospital of Southern Medical University; The Fifth Affiliated Hospital of Zunyi Medical University, Zhuhai, China
Not yet recruiting
Mid-Infrared Spectroscopy as a Real Time Diagnostic Tool for Chronic Endometritis
NCT04197167
Conditions: Endometritis; IVF
Interventions: Procedure: Hysteroscopy; Device: Infrared Spectroscopy
Sponsor: Hillel Yaffe Medical Center
Not yet recruiting
Pain-related Fear as a Facilitator of Nocebo Hyperalgesia
NCT04197154
Conditions: Hyperalgesia; Chronic Pain Syndrome; Chronic Pain, Psychogenic; Fear of Pain
Interventions: Behavioral: Threat manipulation (control, no threat); Behavioral: Threat manipulation; Behavioral: Conditioning of moderate pain; Behavioral: Conditioning of high pain; Behavioral: Extinction
Sponsors: Leiden University Medical Center; Universiteit Leiden; KU Leuven; Maastricht University
Recruiting
Hypofractionated Whole-Pelvis Radiotherapy (WPRT) vs Conventionally-Fractionated WPRT in Prostate Cancer
NCT04197141
Condition: Prostate Cancer
Interventions: Radiation: Conventionally-fractionated WPRT; Radiation: Hypofractionated WPRT
Sponsors: Lawson Health Research Institute; Canadian Association of Radiation Oncology; AbbVie
Not yet recruiting
Lateral Ridge Augmentation Around Implants
NCT04197128
Condition: Alveolar Bone Resorption
Interventions: Device: Resorbable Collagen membrane with bone graft for augmentation; Device: Ribose cross linked collagen matrix for augmentation
Sponsor: Krishnadevaraya College of Dental Sciences & Hospital
Recruiting
Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis
NCT04197115
Conditions: Sepsis; Septic Shock
Interventions: Drug: Vitamin C; Drug: Hydrocortisone; Drug: Complex B
Sponsor: IMSS Hospital General de Zona 11, Piedras Negras
Recruiting
Use of CBD Oil in the Treatment of Posttraumatic Stress Disorder
NCT04197102
Condition: Post Traumatic Stress Disorder
Interventions: Drug: Cannabidiol (CBD) oil; Behavioral: Trauma focused group cognitive-behavioral therapy (CBT); Other: Placebo oil
Sponsor: University of Texas at Austin
Recruiting
Biological Effect of Vitamin D in Patients With Urothelial Carcinoma
NCT04197089
Condition: Urothelial Carcinoma
Intervention: Drug: Vitamin D
Sponsors: Germans Trias i Pujol Hospital; Spanish Clinical Research Network - CAIBER; Centro Nacional de Investigaciones Oncologicas CARLOS III; Fundació Institut Germans Trias i Pujol
Not yet recruiting
Neoadjuvant Therapy in Resectable Non-Small Cell Lung Cancer Stages IIIA
NCT04197076
Condition: Non Small Cell Lung Cancer
Interventions: Drug: anti-PD-1 or anti-PD-L1; Drug: EGFR-TKI, ALK inhibitor, ROS1 inhibitor; Drug: investigator decided
Sponsor: Shanghai Chest Hospital
Recruiting
Sugar-Sweetened Beverage Portion Limit Study
NCT04197063
Condition: Health Policy
Intervention: Behavioral: Sweetened beverage portion size limit
Sponsor: Rutgers, The State University of New Jersey
Completed
Effect of Sacubitril/Valsartan on Reduced Right Ventricular Ejection Fraction in Patients With CTD
NCT04197050
Conditions: Myocardial Injury; Connective Tissue Diseases
Intervention: Drug: Sacubitril / Valsartan Oral Tablet
Sponsor: RenJi Hospital
Not yet recruiting
Prevalence of Sialorrhea in Patients Treated With Clozapine
NCT04197037
Conditions: Sialorrhea; Clozapine Adverse Reaction; Quality of Life
Intervention: Procedure: Evaluation of sialorrhea through questionnaires that measure daytime and nighttime sialorrhea and the impact on quality of life.
Sponsor: Parc de Salut Mar
Recruiting
Assessment of Exercise Capacity in Virtual Reality
NCT04197024
Condition: COPD
Interventions: Device: Exercise capacity test; Device: Exercise capacity test in virtual reality
Sponsor: The Opole University of Technology
Not yet recruiting
Advanced Prosthetic Devices for Lower Limb Amputees
NCT04197011
Condition: Prostheses and Implants
Intervention: Device: prosthetic device
Sponsor: Nottingham Trent University
Recruiting
Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Hepatitis b Virus Related Compensated Cirrhosis
NCT04196998
Conditions: Hepatitis B; Compensated Cirrhosis
Interventions: Drug: Entecavir; Drug: Tenofovir Disoproxil Fumarate; Drug: Tenofovir alafenamide
Sponsor: Third Affiliated Hospital, Sun Yat-Sen University
Recruiting
FDG PET/CT Versus PET/MRI in Detecting Locoregional Recurrence 3 Months After CRT in Head and Neck SCC
NCT04196985
Condition: Head and Neck Squamous Cell Carcinoma
Interventions: Diagnostic Test: PET/MRI; Diagnostic Test: PET/TT
Sponsor: Turku University Hospital
Not yet recruiting
Telementoring Intervention (ECHO) for the Transformation of Professional Engagement, Practice Efficiency, and Community Building Through Team Meetings in Diagnostic Imaging Clinicians
NCT04196972
Condition: Malignant Neoplasm
Interventions: Other: Communication Intervention; Other: Questionnaire Administration; Other: Waiting List
Sponsors: M.D. Anderson Cancer Center; National Cancer Institute (NCI)
Not yet recruiting
Evaluation of TYR Sphere
NCT04196959
Conditions: Tyrosinemias; Alkaptonuria; Tyrosinemia, Type I; Tyrosinemia, Type II; Tyrosinemia, Type III
Intervention: Dietary Supplement: TYR sphere
Sponsor: Vitaflo International, Ltd
Recruiting
Use of Intrathecal Analgesia in Appendectomy
NCT04196946
Conditions: Anesthesia; Analgesia
Interventions: Drug: 25 mcg fentanyl; Drug: 250 mcg alfentanil
Sponsor: Nigde Omer Halisdemir University
Completed
Analysis of Vestibular Compensation Following Vestibular Neurectomy
NCT04196933
Conditions: Migraine; Vestibular Migraine; Vestibular Schwannoma; Motion Sickness; Dizziness; Vestibular Disorder
Interventions: Behavioral: Temporal Binding Adaptation - TBW training; Behavioral: Temporal Binding Adaptation - PSS training; Behavioral: Temporal Binding Adaptation - PSS adaptation with VI stimulation; Behavioral: Chronic Motion-modulated Stimulation
Sponsors: Massachusetts Eye and Ear Infirmary; National Institute on Deafness and Other Communication Disorders (NIDCD); Oregon Health and Science University; University of Geneva, Switzerland
Enrolling by invitation
Methotrexate-associated Anti-TNF Combination Therapy, the Neglected One !
NCT04196920
Condition: Chronic Inflammatory Bowel Disease
Intervention:
Sponsors: University Hospital, Montpellier; Rennes University Hospital - CHU Pontchaillou
Not yet recruiting
[Trial of device that is not approved or cleared by the U.S. FDA]
NCT04196907
Condition:
Intervention:
Sponsor: [Redacted]
Withheld
Ischemic Stroke, Obesity and Thrombolysis
NCT04196894
Condition: Ischemic Stroke
Intervention:
Sponsor: University Hospital Inselspital, Berne
Recruiting
Effect of Attention Deficit Hyperactivity Disorder Knowledge Improvement Program on Male Primary School Teachers
NCT04196881
Conditions: ADHD; Mental Disorder; Attention Deficit Hyperactivity Disorder
Intervention: Other: Knowledge Improvement Program about ADHD
Sponsor: King Khalid University
Active, not recruiting
Methotrexate and Metformin in Rheumatoid Arthritis Patients
NCT04196868
Condition: Arthritis, Rheumatoid
Interventions: Drug: Metformin treatment; Other: Placebo; Drug: Methotrexate treatment
Sponsors: University Hospital, Bordeaux; Ministry for Health and Solidarity, France
Not yet recruiting
Study of Teriparatide in Stress Fracture Healing
NCT04196855
Conditions: Stress Fracture; Parathyroid Hormone
Intervention: Drug: Teriparatide
Sponsors: University of East Anglia; Ministry of Defence, United Kingdom; Darlington Memorial Hospital; Clinical Research and Trials Unit (Norfolk & Norwich University Hospital, UK)
Not yet recruiting
Heart Failure Precision Medicine Study
NCT04196842
Condition: Heart Failure
Intervention: Device: Telemonitoring devices
Sponsor: University of California, Davis
Recruiting

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