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• Relationship-based Care Model in Pediatrics

  NCT04199429

  Conditions:   Depression, Anxiety;   Nurse-Patient Relations
  Intervention:   Behavioral: Relationship-Based Care
  Sponsors:   University of Urbino "Carlo Bo";   University of Padua
  Completed
• Effectiveness of a Mobile App for Individuals With or at Risk of Knee Osteoarthritis

  NCT04199416

  Conditions:   Knee Pain/Osteoarthritis;   Digital Health
  Interventions:   Device: mRehab app;   Device: Sham app
  Sponsor:   The University of Hong Kong
  Not yet recruiting
• Assessment of Complication Risk Factors in a French National Cohort of Asplenic Patients

  NCT04199403

  Condition:   Asplenia
  Intervention:  
  Sponsors:   Poitiers University Hospital;   Pr Pierre BUFFET Institut National de la Transfusion Sanguine;   Pr Sophie CANDON Laboratoire d'immunologie et biothérapies CHU de Rouen;   Dr Edouard TUAILLON Département Bactériologie-Virologie/INSERM U1058 CHU de Montpellier
  Not yet recruiting
• Physical Therapy Following Total Hip Arthroplasty

  NCT04199390

  Conditions:   Hip Osteoarthritis;   Surgery
  Intervention:   Procedure: total hip arthroplasty
  Sponsors:   Orthopedic One;   Medacta USA
  Completed
• Retrospective Evaluation of Clinical and Functional Results and Survivorship of Total Knee Replacement and Total Hip Replacement, Both Isolated or Combined.

  NCT04199377

  Conditions:   HIP REPLACEMENT;   KNEE REPLACEMENT
  Intervention:   Procedure: HIP KNEE REPLACEMENT
  Sponsor:   Istituto Ortopedico Galeazzi
  Recruiting
• Medium vs Low Oxygen Threshold for the Surfactant Administration

  NCT04199364

  Condition:   Respiratory Distress Syndrome
  Intervention:   Drug: Poractant Alfa 80 mg/mL Intratracheal Suspension
  Sponsor:   Virgilio Paolo Carnielli
  Not yet recruiting
• Single and Multiple Ascending Dose Study of AMG 171 in Subjects With Obesity

  NCT04199351

  Condition:   Obesity
  Interventions:   Drug: AMG 171;   Drug: Placebo
  Sponsor:   Amgen
  Not yet recruiting
• The Effect of Web Based Education Based on Self-Care Deficiency Theory on Self-Care Power and Self-Efficacy and Perceived Social Support in Patients Receiving Peritoneal Dialysis

  NCT04199338

  Conditions:   Self-Care;   Self Efficacy;   Perceived Social Support;   Peritoneal Dialysis
  Intervention:   Other: The Effect of Web Based Education Based on Self-Care Deficiency Theory on Self-Care Power and Self-Efficacy and Perceived Social Support in Patients Receiving Peritoneal Dialysis
  Sponsor:   Akdeniz University
  Enrolling by invitation
• Probiotics for Gout / Hyperuricemia: Randomized, Double-blind, Intervention, Parallel Controlled, Multicenter

  NCT04199325

  Conditions:   Gout;   Hyperuricemia
  Interventions:   Dietary Supplement: Probiotics;   Drug: uric-acid-lowering drug
  Sponsor:   The Affiliated Hospital of Inner Mongolia Medical University
  Recruiting
• Magnetic Muscle Stimulation of Abdominal Muscle

  NCT04199312

  Condition:   Body Fat Disorder
  Intervention:   Device: The ZELTIQ System
  Sponsor:   Zeltiq Aesthetics
  Active, not recruiting
• Sensors for Communication for Persons Who Cannot Communicate Unequivocally

  NCT04199299

  Conditions:   Intellectual Disability;   Autism;   Cerebral Palsy
  Intervention:   Device: Heart rate and respiration rate sensors
  Sponsor:   University of Oslo
  Recruiting
• Horizontal Strabismus Surgery

  NCT04199286

  Condition:   Strabismus
  Intervention:   Procedure: symmetrical and asymmetrical horizontal strabismus surgery
  Sponsor:   Minia University
  Completed
• Assessment of Human Diaphragm Strength by Magnetic and Electric Stimulation After Ultrasonography Phrenic Nerve Tracking

  NCT04199273

  Conditions:   Intensive Care Unit;   Invasive Mechanical Ventilation
  Interventions:   Procedure: Magnetic stimulation;   Procedure: Electric stimulation
  Sponsor:   University Hospital, Montpellier
  Not yet recruiting
• Investigation to Evaluate PAPILOCARE® Gel Effect on Normalization of Cervix Cytological Alterations Caused by HPV.

  NCT04199260

  Conditions:   HPV Infection;   Lesion Cervix
  Intervention:   Device: papilocare vaginal gel
  Sponsors:   Procare Health Iberia S.L.;   Adknoma Health Research
  Recruiting
• Early Exercise to Improve Psychosocial Function After Pediatric Mild Traumatic Brain Injury

  NCT04199247

  Conditions:   Brain Concussion;   Pediatric;   Mild Traumatic Brain Injury;   Psychological
  Intervention:   Behavioral: Sub symptom aerobic exercise
  Sponsor:   University of Colorado, Denver
  Not yet recruiting
• Tolerability of AB-Fortis Encapsulated Iron

  NCT04199234

  Condition:   Supplement
  Interventions:   Dietary Supplement: experimental product consumption. (AB Fortis 60 mg);   Dietary Supplement: comparator product consumption. (Iron sulphate.)
  Sponsor:   Universidad Católica San Antonio de Murcia
  Not yet recruiting
• Use of Stress Inoculation Training in Medical Education

  NCT04199221

  Condition:   Stress
  Interventions:   Behavioral: Stress Innoculation Training (SIT);   Behavioral: Extra attempt
  Sponsor:   Virginia Commonwealth University
  Not yet recruiting
• Does Prehabilitation Improve Outcome in Coloncancer Surgery?

  NCT04199208

  Condition:   Surgery--Complications
  Interventions:   Other: Prehabilitation and Immunonutrition;   Other: Standard Care Arm
  Sponsor:   Region Skane
  Not yet recruiting
• Microbiome of the Ageing Gut and Its Effect on Human Gut Health and Cognition.

  NCT04199195

  Condition:   Ageing
  Intervention:  
  Sponsors:   Quadram Institute Bioscience;   Norfolk and Norwich University Hospitals NHS Foundation Trust
  Enrolling by invitation
• Exercise Training to Improve PTSD Symptoms and Health in Older Veterans

  NCT04199182

  Condition:   Post-traumatic Stress Disorder
  Interventions:   Behavioral: Exercise Training;   Other: Healthy Aging Attention Control (HA-ATC)
  Sponsor:   VA Office of Research and Development
  Not yet recruiting
• Safety and Immunogenicity of a Nipah Virus Vaccine

  NCT04199169

  Condition:   Nipah Virus Infection
  Interventions:   Biological: HeV-sG-V;   Biological: Normal Saline Placebo
  Sponsors:   Profectus BioSciences, Inc.;   PATH;   Coalition for Epidemic Preparedness Initiative (CEPI);   Cincinnati Children's Hospital Medical Center (CCHMC)
  Not yet recruiting
• Evaluation of Non-invasive Blood Pressure Measured at the Ankle During Cesarean Delivery Compared to the Arm

  NCT04199156

  Conditions:   Non-invasive Blood Pressure;   Cesarean Delivery;   Spinal Anesthesia
  Intervention:  
  Sponsor:   Kasr El Aini Hospital
  Not yet recruiting
• Brain Reactivity to Nitrous Oxyde in Depression : an MRI and Ultrasound Study (PROTOBRAIN Pilote)

  NCT04199143

  Conditions:   Treatment Resistant Depression;   Nitrous Oxyde
  Interventions:   Drug: Nitrous Oxide-Oxygen;   Device: Tissue Pulsatility Imaging - TPI;   Device: Magnetic Resonance Imaging - MRI
  Sponsor:   University Hospital, Tours
  Not yet recruiting
• Cognitive Rehabilitation and Brain Activity of Attention-Control Impairment in TBI

  NCT04199130

  Condition:   Traumatic Brain Injury
  Interventions:   Behavioral: BrainHQ;   Behavioral: Goal Management Training
  Sponsor:   Catherine Tocci
  Not yet recruiting
• Health Systems Reach Interventions Project

  NCT04199117

  Conditions:   Smoking, Cigarette;   Smoking Cessation
  Interventions:   Drug: Varenicline;   Drug: Combination nicotine patch and nicotine mini-lozenge treatment;   Behavioral: Monetary incentives for initiating treatment;   Behavioral: Automated tailored outreach;   Behavioral: Care management;   Other: Wisconsin Tobacco Quit Line referral;   Other: Primary care provider referral;   Behavioral: Untailored outreach;   Behavioral: Multiple smoking cessation coaching calls
  Sponsors:   University of Wisconsin, Madison;   National Cancer Institute (NCI)
  Not yet recruiting
• A Study of Pembrolizumab (MK-3475) With or Without Lenvatinib (E7080/MK-7902) as First Line (1L) Intervention in a Programmed Cell Death-ligand 1 (PD-L1) Selected Population With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (R/M HNSCC) (LEAP-010) (MK-7902-010)

  NCT04199104

  Condition:   Head and Neck Squamous Cell Carcinoma
  Interventions:   Drug: Lenvatinib;   Drug: Pembrolizumab;   Drug: Placebo
  Sponsor:   Merck Sharp & Dohme Corp.
  Not yet recruiting
• Craniosacral Therapy as a Self-help Strategy for Patients With Chronic Non-specific Back Pain

  NCT04199091

  Conditions:   Low Back Pain, Mechanical;   Complementary Therapies;   Progressive Muscle Relaxation
  Interventions:   Procedure: Craniosacral Therapy (CST) self-help techniques;   Procedure: Progressive Muscle Relaxation (PMR)
  Sponsor:   Universität Duisburg-Essen
  Not yet recruiting
• Clinical Trial to Explore Papilocare Gel Efficacy to Repair of the Cervico-vaginal Mucosa With HPV High Risk Lesions.

  NCT04199078

  Conditions:   Human Papilloma Virus;   Human Papilloma Virus Infection;   Cervix Lesion
  Intervention:   Device: Papilocare vaginal gel
  Sponsors:   Procare Health Iberia S.L.;   Adknoma Health Research
  Recruiting
• Impact of Good Practice Guidelines on Evidence-based Practice and Nurses' Work Environment

  NCT04199065

  Conditions:   Nurses' Work Environment;   Committed Centers With Excellence in Care (CCEC®) Program;   Nurses' Evidence-based-practice Attitudes;   Nurse Physician Relations;   Practice Nurse's Scope;   Professional Stress
  Intervention:   Other: Good Practice Guidelines implementation
  Sponsors:   Parc de Salut Mar;   IMIM, Institut Hospital del Mar d'Investigacions Mèdiques;   COIB, Col·legi d'Infermers i infermeres de Barcelona;   Department of Health, Generalitat de Catalunya (PERIS)
  Active, not recruiting
• LinkPositively: A Technology-Delivered Peer Navigation and Social Networking Intervention to Improve HIV Care

  NCT04199052

  Condition:   HIV/AIDS
  Intervention:   Behavioral: LinkPositively
  Sponsors:   University of California, San Diego;   San Diego State University;   National Institute of Mental Health (NIMH)
  Not yet recruiting
• Effects of Endotracheal Tube Fixation Methods on Hemodynamic Parameters During Endotracheal Suction

  NCT04199039

  Condition:   Cardiac Surgery
  Intervention:   Other: Effect on Endotracheal Tube Fixation Methods on Hemodynamic Parameters During Endotracheal Suction
  Sponsor:   Mersin University
  Completed
• Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma

  NCT04199026

  Conditions:   Metastatic Sarcoma;   Recurrent Sarcoma;   Resectable Sarcoma
  Interventions:   Drug: Doxorubicin;   Drug: Doxorubicin Hydrochloride;   Device: Drug Delivery Microdevice;   Drug: Everolimus;   Biological: Ganitumab;   Drug: Ifosfamide;   Drug: Irinotecan;   Drug: Pazopanib;   Drug: Polyethylene Glycol;   Drug: Temozolomide;   Drug: Temsirolimus;   Procedure: Therapeutic Conventional Surgery;   Drug: Vincristine
  Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI)
  Not yet recruiting
• Comparison of Ropivacaine With or Without Fentanyl in Spinal Anaesthesia for Lower Limb Surgeries

  NCT04199013

  Conditions:   Leg Injury;   Arthroplasty, Replacement, Knee
  Interventions:   Drug: Ropivacaine 0.75% Injectable Solution;   Drug: Fentanyl Citrate
  Sponsor:   Tribhuvan University Teaching Hospital, Institute Of Medicine.
  Not yet recruiting
• Clinical and Basic Investigations Into Congenital Disorders of Glycosylation

  NCT04199000

  Condition:   Congenital Disorders of Glycosylation
  Intervention:  
  Sponsors:   Mayo Clinic;   National Institute of Neurological Disorders and Stroke (NINDS)
  Recruiting
• Dietary Monosaccharide Supplementation in Patients With Congenital Disorders of Glycosylation

  NCT04198987

  Condition:   Congenital Disorder of Glycosylation
  Intervention:  
  Sponsor:   Mayo Clinic
  Recruiting
• The Canadian Underage Substance Use Prevention Trial

  NCT04198974

  Conditions:   Substance Use Disorders;   Adolescent Behavior;   Adolescent Development
  Interventions:   Behavioral: PreVenture Training (PTtT);   Behavioral: PreVenture Training+Implementation Facilitation
  Sponsors:   St. Justine's Hospital;   University of British Columbia;   Center for Addiction and Mental Health;   Dalhousie University;   Canadian Institutes of Health Research (CIHR)
  Recruiting
• Electronic Intervention to Chronic Opioid Therapy

  NCT04198961

  Condition:   Chronic Opioid Therapy
  Intervention:   Other: opioid prescribing
  Sponsor:   Stanford University
  Not yet recruiting
• Interaction Between Omeprazole and Gliclazide in CYP2C19 Normal/ Ultrarapid Metabolisers

  NCT04198948

  Condition:   Diabetes Mellitus, Type 2
  Interventions:   Drug: Omeprazole;   Drug: Placebo oral tablet;   Drug: Gliclazide
  Sponsors:   University of Sarajevo;   General Hospital Prim. Dr. Abdulah Nakas;   University of Dundee
  Completed
• Evaluating a Digital Diabetes Education Program

  NCT04198935

  Condition:   Diabetes Mellitus, Type 2
  Intervention:   Device: Span Health Mobile Application
  Sponsor:   Adam Bataineh
  Not yet recruiting
• Acalabrutinib for the Treatment of Chronic Graft Versus Host Disease

  NCT04198922

  Condition:   Recurrent Moderate-Severe Chronic Graft Versus Host Disease
  Interventions:   Drug: Acalabrutinib;   Other: Questionnaire Administration
  Sponsors:   Fred Hutchinson Cancer Research Center;   National Cancer Institute (NCI);   AstraZeneca
  Not yet recruiting
• Optimization of a Non-invasive Electrophysiological Method for Studying the Functionality of Auditory Nerve Fibers

  NCT04198909

  Conditions:   Healthy Volunteer;   Without Hearing Disorders
  Intervention:   Diagnostic Test: Electrocochleography, electrophysiology thet for analyse the wave I generated by the auditory pathways
  Sponsors:   University Hospital, Clermont-Ferrand;   Laboratory of Neurosensory Biophysics - UMR INSERM 1107.;   Foundation of Gueules Cassées;   Region of Auvergne-Rhône-Alpes
  Recruiting
• The Sakakibara Health Integrative Profile of Atherosclerotic-Carcinogenesis Hypothesis (SHIP-AC)

  NCT04198896

  Conditions:   Cancers;   Atheroscleroses, Coronary;   Atherosclerosis of Artery
  Intervention:   Other: incidece of cancers
  Sponsor:   Sakakibara Heart Institute
  Completed
• SINGaporean Program Performed With an eXPANsion Medical Device (SingXpand)

  NCT04198883

  Condition:   Heart Attack
  Intervention:   Combination Product: Protheracytes
  Sponsor:   CellProthera
  Active, not recruiting
• MitraClip REPAIR MR Study

  NCT04198870

  Condition:   Mitral Valve Regurgitation
  Interventions:   Device: MitraClip™ device implantation;   Procedure: Mitral Valve Repair Surgery
  Sponsor:   Abbott Medical Devices
  Not yet recruiting
• Development and Testing of a Mobile Health Application for Management of Gestational Diabetes

  NCT04198857

  Conditions:   Diabetes, Gestational;   Telemedicine
  Intervention:   Behavioral: Develop a mobile app that supports self- management and treatment for Nepalese GDM patients
  Sponsors:   Rutgers, The State University of New Jersey;   Nepal Health Research Council;   University of Connecticut;   John E. Fogarty International Center (FIC);   Dhulikhel Hospital
  Not yet recruiting
• The Effectiveness and Safety of Apixaban in NVAF Patients With History of Osteoporosis and/or Fracture: A Nation-wide Population Based Study

  NCT04198844

  Condition:   Atrial Fibrillation
  Interventions:   Drug: warfarin;   Drug: apixaban
  Sponsor:   Pfizer
  Active, not recruiting
• Effect of Acupuncture on Quiescent Crohn's Disease

  NCT04198831

  Conditions:   Inflammatory Bowel Diseases;   Crohn Disease
  Interventions:   Other: acupuncture;   Other: Sham acupuncture
  Sponsors:   Shanghai Institute of Acupuncture, Moxibustion and Meridian;   Fudan University;   Shanghai University of Traditional Chinese Medicine;   Ruijin Hospital;   Indiana University School of Medicine
  Recruiting
• A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of HH2710 in Patient With Advanced Tumors

  NCT04198818

  Conditions:   Advanced Tumors;   Melanoma;   Non-Small-Cell Lung Cancer;   Erdheim-Chester Disease;   Other RAS/RAF/MEK/ERK Mutated Tumors
  Intervention:   Drug: HH2710
  Sponsor:   ShangHai HaiHe Pharmaceutical
  Not yet recruiting
• Vitamin E and DHA-EE on NAFLD - Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Clinical Trial (PUVENAFLD)

  NCT04198805

  Conditions:   Non-Alcoholic Fatty Liver Disease;   Non-Alcoholic Fatty Liver;   Non-Alcoholic Steatohepatitis
  Interventions:   Dietary Supplement: Vitamin E [(all-rac)-α-tocopheryl acetate];   Dietary Supplement: Omega-3 fatty acid (DHA EE);   Combination Product: Omega-3 fatty acid (DHA EE) & Vitamin E [(all-rac)-α-tocopheryl acetate];   Other: Placebo
  Sponsors:   Naga P. Chalasani;   DSM Nutritional Products, Inc.
  Recruiting
• Predictors for Survival and Good Neurological Outcome in E-CPR and Non CPR Treated Patients

  NCT04198792

  Conditions:   Cardiac Arrest;   Extracorporeal Membrane Oxygenation;   Hypoxia-Ischemia, Brain
  Intervention:   Other: No intervention
  Sponsor:   Sahlgrenska University Hospital, Sweden
  Recruiting
• Interest of the Smartphone Application "MonCœur" in the Follow-up of Patients With Heart Failure

  NCT04198779

  Conditions:   Heart Failure;   Heart Decompensation
  Intervention:   Device: APPLI
  Sponsor:   French Cardiology Society
  Not yet recruiting
• Study of INBRX-106 in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

  NCT04198766

  Conditions:   Solid Tumor;   Non-Small Cell Lung Cancer;   Melanoma;   Head and Neck Cancer;   Gastric Cancer;   Renal Cell Carcinoma;   Urothelial Carcinoma
  Interventions:   Drug: INBRX-106 - Hexavalent OX40 agonist antibody;   Drug: Pembrolizumab
  Sponsor:   Inhibrx, Inc.
  Recruiting
• Skin Characteristics of Parents of Food Allergic Pediatric Patients

  NCT04198753

  Condition:   Food Allergy in Children
  Interventions:   Diagnostic Test: Skin tape stripping;   Device: Skin barrier assessment;   Diagnostic Test: Blood draw
  Sponsor:   National Jewish Health
  Not yet recruiting
• Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface

  NCT04198740

  Conditions:   Dry Eye Syndrome;   Infectious Keratoconjunctivitis;   Mucous Membrane Pemphigoid;   Allergic Conjunctivitis
  Intervention:   Diagnostic Test: Tear sample collection via Schirmer strip and subsequent analysis by mass spectrometry
  Sponsors:   Centre hospitalier de l'Université de Montréal (CHUM);   Université du Québec a Montréal
  Not yet recruiting
• Study of the Impact of DPD Activity on the Efficacy of Capecitabine

  NCT04198727

  Condition:   Breast Neoplasm Malignant Female
  Interventions:   Other: DPD activity assessment;   Drug: Capecitabine
  Sponsors:   Centre Antoine Lacassagne;   Cerbaliance
  Not yet recruiting
• Pudendal Nerve Block in Vaginal Surgery

  NCT04198714

  Conditions:   Nerve Block;   Pain, Postoperative;   Pelvic Floor Disorders;   Pelvic Organ Prolapse;   Pudendal Neuralgia;   Surgery
  Intervention:   Procedure: Pudendal block
  Sponsor:   MetroHealth Medical Center
  Recruiting
• Pulsed Field Ablation to Irreversibly Electroporate Tissue and Treat AF

  NCT04198701

  Condition:   Atrial Fibrillation
  Intervention:   Device: Medtronic Pulsed Field Ablation (PFA) System
  Sponsor:   Medtronic Cardiac Rhythm and Heart Failure
  Not yet recruiting
• Effectiveness of Intensive Smoking Cessation Interventions in Patients With Cancer

  NCT04198688

  Conditions:   Tobacco Smoking;   Cancer;   Tobacco Cessation
  Intervention:   Behavioral: Intensive Smoking Cessation Intervention
  Sponsors:   Bispebjerg Hospital;   Rigshospitalet, Denmark;   Aarhus University Hospital Skejby;   Danish Cancer Society
  Completed
• Effects of Preventive Physiotherapy Practices on Posture and Work-Related Functions in Office Workers

  NCT04198675

  Conditions:   Work-related Musculoskeletal Disorders;   Office Workers
  Interventions:   Behavioral: Supervised EMG Biofeedback Exercise Training Group;   Behavioral: Home-Based Exercise Training Group;   Behavioral: Posture Training/Ergonomic Regulations Group
  Sponsors:   Marmara University;   Hacettepe University
  Active, not recruiting
• Rib Fracture Analgesia Using Cryoanalgesia

  NCT04198662

  Condition:   Traumatic Rib Fracture(s)
  Interventions:   Device: Cryoneurolysis with a Painblocker (Epimed International, Farmers Branch, Texas);   Drug: Intercostal nerve block ropivacaine with epinephrine
  Sponsors:   University of California, San Diego;   University of Florida;   Epimed International
  Recruiting
• Effect of Azithromycin on Failure Proportion of Severe Periodontitis Non-surgical Treatment

  NCT04198649

  Condition:   Severe Chronic Periodontitis
  Interventions:   Drug: Non-surgical periodontal treatment and azithromycin treatment;   Other: Non-surgical periodontal treatment and placebo treatment
  Sponsor:   University Hospital, Strasbourg, France
  Not yet recruiting
• A Study to Evaluate LY01011 and Xgeva® in Healthy Adults

  NCT04198636

  Condition:   Healthy Adults
  Interventions:   Drug: LY01011;   Drug: Xgeva 120 MG in 1.7 ML Injection
  Sponsors:   Luye Pharma Group Ltd.;   Shang Dong Boan Biotechnology Co., Ltd (Co-sponsor)
  Not yet recruiting
• Efficacy of Montelukast in Reducing the Incidence and Severity of Monoclonal Antibodies Associated Infusion Reactions

  NCT04198623

  Conditions:   Infusion Reaction;   Monoclonal Antibody
  Intervention:   Drug: Montelukast 10 Mg Oral Tablet
  Sponsor:   University of California, San Francisco
  Not yet recruiting
• Evaluation and Correlation of Serum Fetuin-A Levels in Periodontal Health and Disease: A Clinico-biochemical Study

  NCT04198610

  Condition:   Gingivitis and Periodontal Diseases
  Intervention:   Procedure: Non surgical periodontal therapy
  Sponsor:   Krishnadevaraya College of Dental Sciences & Hospital
  Completed
• Exploring Two Treatments for Misophonia

  NCT04198597

  Condition:   Misophonia
  Interventions:   Behavioral: Unified Protocol for Transdiagnostic Treatment of Emotional Disorders;   Behavioral: Process-based Cognitive Behavioral Therapy
  Sponsor:   Duke University
  Not yet recruiting
• Study of Telemedicine Stress Management and Lifestyle Group Intervention for HCV Patients

  NCT04198584

  Condition:   Chronic Hepatitis C
  Intervention:   Behavioral: VC-CBCS
  Sponsors:   University of North Carolina, Chapel Hill;   Duke University;   National Institute of Nursing Research (NINR)
  Not yet recruiting
• Retrospective Chart Review Study to Assess Characteristics, Treatment Outcomes and Resource Use of Adults Hospitalized for CAP and CSSTi Treated With Zinforo in Multiple Countries

  NCT04198571

  Conditions:   Community Acquired Pneumonia;   Complicated Skin and Soft Tissue Infection
  Intervention:   Drug: Zinforo (ceftaroline fosamil)
  Sponsor:   Pfizer
  Not yet recruiting
• A Study of the Safety, Tolerability and Pharmacokinetics of MEDI0618 in Healthy Volunteers

  NCT04198558

  Condition:   Chronic Pain
  Interventions:   Drug: MEDI0618;   Drug: Placebo
  Sponsor:   AstraZeneca
  Recruiting
• Ethnic Differences in Iron Absorption (FeGenes)

  NCT04198545

  Conditions:   Anemia, Iron Deficiency;   Iron Overload
  Intervention:  
  Sponsors:   Cornell University;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   Office of Dietary Supplements (ODS)
  Recruiting
• Contrast Bath and Sympathetic Skin Response

  NCT04198532

  Conditions:   Stroke;   Sympathetic Disorder
  Intervention:   Other: Contrast bath
  Sponsor:   Istanbul Physical Medicine Rehabilitation Training and Research Hospital
  Completed
• Effects of Weight Loss on Vascular Function in Obese Subjects

  NCT04198519

  Condition:   Obesity
  Intervention:   Other: Weight Loss
  Sponsors:   Mario Fritsch Neves;   Rio de Janeiro State Research Supporting Foundation (FAPERJ);   Conselho Nacional de Desenvolvimento Científico e Tecnológico
  Recruiting
• Viral Load Guided Immunosuppression After Lung Transplantation

  NCT04198506

  Condition:   Transplantation Lung
  Interventions:   Other: Tailored tacrolimus dosing;   Other: Conventional tacrolimus dosing
  Sponsor:   Philipps University Marburg Medical Center
  Not yet recruiting
• Effect of CPAP Treatment in Cognition in Adults With DS and OSA

  NCT04198493

  Condition:   Obstructive Sleep Apnea
  Interventions:   Device: CPAP;   Other: CONSERVATIVE TREATMENT FOR OSA
  Sponsor:   Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
  Not yet recruiting
• A Clinical Trial to Assess the Efficacy and Safety of JMT103 in Patients With Refractory HCM

  NCT04198480

  Condition:   Hypercalcemia of Malignancy
  Intervention:   Drug: JMT103
  Sponsors:   Shanghai JMT-Bio Inc.;   CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
  Not yet recruiting
• To Evaluate the Optimum Dose of Platelet Rich Plasma in Knee Osteoarthritis and Compare Efficacy With Hyaluronic Acid

  NCT04198467

  Condition:   Knee Osteoarthritis
  Interventions:   Biological: Platelet rich plasma;   Drug: Hyaluronic Acid
  Sponsor:   Dr. Himanshu Bansal Foundation
  Completed
• Compression and CO2 Laser for Leg Wounds

  NCT04198454

  Condition:   Wound Healing
  Interventions:   Other: Compression bandages;   Other: Standard wound dressings;   Device: Fractional ablative carbon dioxide laser
  Sponsor:   Northwestern University
  Not yet recruiting
• The Omeza Protocol for Chronic Ulcers

  NCT04198441

  Conditions:   Venous Leg Ulcer;   Diabetic Foot Ulcer
  Intervention:   Device: Wound dressing
  Sponsor:   Omeza, LLC
  Not yet recruiting
• Clinical Decision Support for Opioid Use Disorders in Medical Settings (COMPUTE 2.0)

  NCT04198428

  Condition:   Opioid-use Disorder
  Intervention:   Other: Opioid Wizard
  Sponsors:   HealthPartners Institute;   National Institute on Drug Abuse (NIDA);   The Emmes Company, LLC;   Hennepin Healthcare Research Institute.
  Recruiting
• A Study of the Safety and Efficacy of Venetoclax in Japanese Participants With Relapsed and Refractory Chronic Lymphocytic Leukemia (Including Small Lymphocytic Leukemia)

  NCT04198415

  Conditions:   Cancer;   Chronic Lymphocytic Leukemia (CLL);   Small Lymphocytic Leukemia (SLL)
  Intervention:  
  Sponsor:   AbbVie
  Not yet recruiting
• Microbiotic Analysis in Digestive Endocrine Tumors

  NCT04198402

  Conditions:   Digestive Neuroendocrine Tumor;   Fecal Microbiota;   Bacterial Signature
  Intervention:   Biological: Biological sampling
  Sponsor:   Assistance Publique - Hôpitaux de Paris
  Not yet recruiting
• Retrospective Clinical and Functional Evaluation of Patients Undergoing Knee Replacement With Small Implants

  NCT04198389

  Condition:   KNEE REPLACEMENT
  Intervention:   Procedure: PARTIAL KNEE REPLACEMENT
  Sponsor:   Istituto Ortopedico Galeazzi
  Active, not recruiting
• The Laterally Closed Tunnel Versus Modified Coronally Advanced Tunnel With Subepithelial Connective Tissue Graft for Treatment of Deep Isolated Mandibular Anterior Gingival Recession Defects

  NCT04198376

  Condition:   Gingival Recession, Localized
  Interventions:   Procedure: Group A The Laterally Closed Tunnel Technique with SCTG;   Procedure: Group B Modified Coronally Advanced Tunnel Technique with SCTG.
  Sponsor:   Krishnadevaraya College of Dental Sciences & Hospital
  Enrolling by invitation
• A Study to Evaluate the Efficacy and Safety of Bismuth-Containing Quadruple Therapy With Oral Vonoprazan (TAK-438) 20 mg Compared to Esomeprazole 20 mg Twice Daily in Paticipants With Helicobacter Pylori Infection

  NCT04198363

  Condition:   Helicobacter Pylori
  Interventions:   Drug: Vonoprazan;   Drug: Amoxicillin;   Drug: Clarithromycin;   Drug: Bismuth Potassium citrate;   Drug: Esomeprazole
  Sponsor:   Takeda
  Not yet recruiting
• Pancreatic Islet Transplantation to the Anterior Chamber of the Eye

  NCT04198350

  Conditions:   Type 1 Diabetes;   Visual Impairment
  Intervention:   Procedure: Islet implantation
  Sponsor:   Imperial College London
  Not yet recruiting
• Endoscopic Full Thickness Resection for Gastric GIST

  NCT04198337

  Condition:   Gastric GIST
  Intervention:   Procedure: Endoscopic Full Thickness Resection
  Sponsor:   Chinese University of Hong Kong
  Recruiting
• Isthmocele After Endometrial and Non-endometrial Suturing in Cesarean Section

  NCT04198324

  Conditions:   Cesarean Section; Dehiscence;   Cesarean Wound; Dehiscence
  Interventions:   Procedure: Closure of the uterus with endometrium at the time of cesarean;   Procedure: Closure of the uterus without endometrium at the time of cesarean
  Sponsor:   Kocaeli University
  Not yet recruiting
• The Impact of CBT for Insomnia on Alcohol Treatment Outcomes

  NCT04198311

  Conditions:   Insomnia;   Alcohol Use Disorder
  Interventions:   Behavioral: CBT-I;   Behavioral: Sleep Hygiene
  Sponsor:   University of Missouri-Columbia
  Not yet recruiting
• Prospective Clinical Trial of Three Apical Sealing Materials

  NCT04198298

  Condition:   Periapical Abscess
  Interventions:   Drug: EndoSequence;   Drug: ProRoot MTA;   Drug: Biodentine
  Sponsor:   University of the Pacific
  Completed
• Post-Operative Voiding After Gynecological Surgery Trial

  NCT04198285

  Conditions:   Urinary Retention;   Postoperative Complications;   Surgery
  Intervention:   Procedure: Retrograde bladder filling
  Sponsor:   Women's College Hospital
  Not yet recruiting
• Impact Evaluation of CyberRwanda

  NCT04198272

  Conditions:   Pregnancy in Adolescence;   Adolescent Health;   Health Services Accessibility
  Intervention:   Behavioral: CyberRwanda
  Sponsors:   University of California, Berkeley;   Youth Development Labs;   Society for Family Health, Rwanda
  Not yet recruiting
• Interventional Devascularization Plus HVPG‐Guided Carvedilol Therapy vs TIPS

  NCT04198259

  Conditions:   Gastric Varices Bleeding;   Liver Cirrhoses
  Interventions:   Procedure: interventional devascularization;   Procedure: TIPS
  Sponsor:   Fourth Military Medical University
  Not yet recruiting
• Chinese ET Registry (CETR)

  NCT04198246

  Condition:   Essential Tremor
  Intervention:  
  Sponsor:   Xiangya Hospital of Central South University
  Recruiting
• Impact of Placement of a Diazepam Suppository on Early Postoperative Pain Following Pelvic Reconstructive Surgery

  NCT04198233

  Condition:   Postoperative Pain
  Interventions:   Drug: Diazepam;   Drug: Placebos
  Sponsor:   TriHealth Inc.
  Not yet recruiting
• BIO|STREAM.ICM Obesity

  NCT04198220

  Conditions:   Tachycardia Atrial;   Atrial Fibrillation;   Syncope;   Bradycardia;   Cryptogenic Stroke
  Intervention:  
  Sponsor:   Biotronik SE & Co. KG
  Not yet recruiting
• The Effectiveness and Safety of Vagus Nerve Stimulation for TRE

  NCT04198207

  Conditions:   Tuberous Sclerosis Complex;   Epilepsy
  Intervention:  
  Sponsors:   Beijing Children's Hospital;   Beijing Tiantan Hospital;   First Hospital of Jilin University;   Xuanwu Hospital, Beijing;   Sanbo Brain Hospital Capital Medical University;   Peking University First Hospital;   China-Japan Friendship Hospital;   Chinese PLA General Hospital;   Fourth Medical Center of PLA General Hospital;   Capital Institute of Pediatrics, China;   The Second Hospital of Hebei Medical University;   Xijing Hospital;   First Affiliated Hospital Xi'an Jiaotong University;   Children's Hospital of Fudan University;   RenJi Hospital;   Jining Medical University;   Xiamen Humanity Hospital;   Xiangya Hospital of Central South University;   Wuhan Medical Care Center for Women and Children;   Guangdong 999 Brain Hospital;   Shenzhen Children's Hospital;   Xinqiao Hospital, Army Medical University;   West China Hospital
  Not yet recruiting
• Apple Heart & Movement Study

  NCT04198194

  Condition:   Prevention
  Intervention:   Diagnostic Test: Predictors of events
  Sponsors:   Brigham and Women's Hospital;   Apple Inc.;   American Heart Association
  Recruiting
• The Effectiveness and Safety of Resective Epilepsy Surgery for TRE

  NCT04198181

  Conditions:   Tuberous Sclerosis Complex;   Epilepsy
  Intervention:  
  Sponsors:   Beijing Children's Hospital;   Beijing Tiantan Hospital;   First Hospital of Jilin University;   Xuanwu Hospital, Beijing;   Sanbo Brain Hospital Capital Medical University;   Peking University First Hospital;   China-Japan Friendship Hospital;   Chinese PLA General Hospital;   Fourth Medical Center of PLA General Hospital;   Capital Institute of Pediatrics, China;   The Second Hospital of Hebei Medical University;   Xijing Hospital;   First Affiliated Hospital Xi'an Jiaotong University;   Children's Hospital of Fudan University;   RenJi Hospital;   Jining Medical University;   Xiamen Humanity Hospital;   Xiangya Hospital of Central South University;   Wuhan Medical Care Center for Women and Children;   Guangdong 999 Brain Hospital;   Shenzhen Children's Hospital;   Xinqiao Hospital, Army Medical University;   West China Hospital
  Not yet recruiting
• The Predictive Performance of Renal Ultrasound on Changes in Renal Clearance

  NCT04198168

  Conditions:   Acute Kidney Injury;   Hypoperfusion;   Fluid Overload
  Intervention:   Drug: IV crystalloid fluid bolus
  Sponsor:   Aarhus University Hospital
  Recruiting
• Renal Denervation Using Stereotactic Radiotherapy System for the Treatment of Refractory Hypertension

  NCT04198155

  Condition:   Hypertension
  Intervention:   Radiation: stereotactic body radiotherapy (SBRT)
  Sponsor:   Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
  Not yet recruiting
• Psychiatric Inpatient Nightmare Treatment

  NCT04198142

  Conditions:   Nightmare;   Psychiatric Disorder
  Interventions:   Behavioral: Imagery Rehearsal Therapy;   Behavioral: Treatment as Usual with dream diaries
  Sponsors:   University of Zurich;   Swiss National Science Foundation;   Psychiatric University Hospital, Zurich
  Recruiting
• The Evaluation of Postoperative Antibiotics in Non-Infected Mandible Fractures

  NCT04198129

  Conditions:   Jaw Fractures;   Infection
  Interventions:   Drug: Antibiotic treatment (Unasyn or Clindamycin);   Drug: Antibiotic treatment (Augmentin or Clindamycin);   Other: Control Group
  Sponsor:   The University of Texas Health Science Center, Houston
  Not yet recruiting
• Combining Varenicline and Guanfacine for Smoking Cessation

  NCT04198116

  Condition:   Smoking Cessation
  Interventions:   Drug: Varenicline;   Drug: Varenicline + Guanfacine ER
  Sponsors:   Yale University;   National Institute on Drug Abuse (NIDA)
  Not yet recruiting
• Transperineal Laser Ablation for Percutaneous Treatment of Benign Prostatic Hyperplasia

  NCT04198103

  Conditions:   BPH;   Lower Urinary Tract Symptoms
  Intervention:   Device: Transperineal Focal Laser Ablation (TPLA)
  Sponsors:   University of Rome Tor Vergata;   Ospedale Regina Apostolorum;   European Institute of Oncology
  Active, not recruiting
• Sexual & Gender Minority Competency in Oncology

  NCT04198090

  Condition:   Neoplasms
  Intervention:   Behavioral: SGM Competency Training Program
  Sponsor:   University of Rochester
  Not yet recruiting
• Conservative Versus Conventional Oxygen Administration in Critically Ill Patients

  NCT04198077

  Conditions:   Critical Illness;   Respiration, Artificial;   Hyperoxia;   Hyperoxemia
  Intervention:   Drug: Oxygen
  Sponsor:   University of Modena and Reggio Emilia
  Recruiting
• Pain Management for Cystoscopy: A Prospective Randomized Study Focused on Understanding the Role of the "Bag Squeeze" to Manage Pain for Patients Undergoing Cystoscopy

  NCT04198064

  Condition:   Pain, Procedural
  Interventions:   Procedure: Bag Squeeze;   Procedure: No Bag Squeeze
  Sponsor:   University Health Network, Toronto
  Completed
• The Clinical Study of Adjuvant Chemotherapy on Intestinal and Urethral Flora in Patients With Gastric and Colon Cancer

  NCT04198051

  Conditions:   Gastric Cancer;   Colon Cancer
  Intervention:   Drug: adjuvant chemotherapy
  Sponsor:   The First Affiliated Hospital of Dalian Medical University
  Recruiting
• Family-Centered Songwriting in Pediatric Palliative Care

  NCT04198038

  Condition:   Cognitive Impairment
  Intervention:   Behavioral: Songwriting with licensed music therapist
  Sponsor:   Vanderbilt University
  Not yet recruiting
• Psoas Density in Colorectal Cancer

  NCT04198025

  Condition:   Cancer of Colon
  Intervention:  
  Sponsor:   University of Nottingham
  Not yet recruiting
• An Open Label Study to Allow Patients Continuous Use of the HemoCare™ Hemodialysis System

  NCT04198012

  Condition:   End Stage Renal Disease
  Intervention:   Device: HemoCare™ Hemodialysis System
  Sponsors:   Deka Research and Development;   CVS Kidney Care LLC.
  Not yet recruiting
• A Study to Determine Safety and Tolerability of GMI-1359 in Subjects With HR+ Metastatic Breast Cancer

  NCT04197999

  Conditions:   HR+ Metastatic Breast Cancer;   Breast Cancer;   Breast Cancer Metastatic
  Intervention:   Drug: GMI-1359
  Sponsor:   GlycoMimetics Incorporated
  Recruiting
• Study of Oral Infigratinib for the Adjuvant Treatment of Subjects With Invasive Urothelial Carcinoma With Susceptible FGFR3 Genetic Alterations

  NCT04197986

  Conditions:   Upper Tract Urothelial Carcinomas;   Urothelial Bladder Cancer
  Interventions:   Drug: Infigratinib;   Drug: Placebo
  Sponsor:   QED Therapeutics, Inc.
  Not yet recruiting
• Association Between Self-reported Web-based SCCAI and Health-related Quality of Life Index in UC Patients

  NCT04197973

  Conditions:   Quality of Life;   Ulcerative Colitis
  Intervention:  
  Sponsors:   YooJin Lee;   Inje University;   Gangnam Severance Hospital;   Jeju National University Hospital;   Soonchunhyang University Hospital
  Not yet recruiting
• Microwave Ablation and Surgical Resection for Micropapillary Thyroid Carcinoma

  NCT04197960

  Condition:   Papillary Thyroid Carcinoma
  Interventions:   Procedure: Microwave ablation;   Procedure: Surgical resection
  Sponsor:   Chinese PLA General Hospital
  Not yet recruiting
• Selectively Modulating Pathophysiological Biomaker to Improve Freezing of Gait in Parkinson' s Disease by Adaptive Subthalamic Stimulation

  NCT04197947

  Conditions:   Freezing of Gait;   Parkinson Disease
  Intervention:   Device: Neuro Omega
  Sponsor:   Chang Gung Memorial Hospital
  Recruiting
• WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

  NCT04197934

  Conditions:   Anaplastic Astrocytoma, IDH-Wildtype;   Glioblastoma, IDH-Wildtype;   Lung Non-Small Cell Carcinoma;   Metastatic Malignant Neoplasm in the Central Nervous System;   Metastatic Malignant Neoplasm in the Leptomeninges
  Interventions:   Drug: EGFR/EGFRvIII Inhibitor WSD0922-FU;   Procedure: Therapeutic Conventional Surgery
  Sponsors:   Mayo Clinic;   National Cancer Institute (NCI)
  Not yet recruiting
• Exablate for LIFU Neuromodulation in Patients With Opioid Use Disorder (OUD)

  NCT04197921

  Condition:   Opioid-use Disorder
  Intervention:   Device: Exablate Model 4000 Type 2.0/2.1
  Sponsor:   InSightec
  Recruiting
• EUS-guided Gallbladder Drainage Instead of Laparoscopic Cholecystectomy for Acute Cholecystitis. A Feasibility Study.

  NCT04197908

  Condition:   Acute Cholecystitis
  Intervention:   Device: EUS-guided gallbladder drainage (EGBD)
  Sponsor:   Chinese University of Hong Kong
  Not yet recruiting
• Clinical and Radiographic Evaluation of Advanced Platelet Rich Fibrin in the Preservation of Alveolar Ridge Following Atraumatic Tooth Extraction

  NCT04197895

  Condition:   Socket Preservation
  Interventions:   Procedure: Socket preservation with APRF;   Procedure: natural healing
  Sponsor:   Nahed Gamal Saleh Abdelaal
  Not yet recruiting
• Clinical Study to Evaluate OrienX010 in Combination With Treprizumab Injection as Neoadjuvant Treatment in Melanoma

  NCT04197882

  Condition:   Melanoma (Skin)
  Intervention:   Biological: OrienX010 Combination with Treprizumab injection
  Sponsor:   Beijing Cancer Hospital
  Recruiting
• Does a Preoperative Bowel Regimen Change Time to First Bowel Movement After Robotic Sacral Colpopexy

  NCT04197869

  Conditions:   Constipation;   Post-Op Complication
  Intervention:   Drug: Polyethylene Glycol Powder
  Sponsor:   Northwell Health
  Recruiting
• Direct Information to At-risk Relatives

  NCT04197856

  Conditions:   Familial Breast Cancer;   Familial Colorectal Cancer;   Hereditary Breast and Ovarian Cancer Syndrome;   Hereditary Breast Cancer;   Lynch Syndrome
  Interventions:   Other: Standard care encouraging family-mediated disclosure of hereditary cancer risk;   Other: Offer of health-care assisted disclosure by sending direct letters to at-risk relatives
  Sponsors:   Umeå University;   Göteborg University;   Lund University;   Karolinska Institutet
  Not yet recruiting
• Navicam as a Triage Tool in the Management of Patients With Acute Upper Gastrointestinal Bleeding

  NCT04197843

  Condition:   GastroIntestinal Bleeding
  Intervention:   Device: NaviCam (ANKON)
  Sponsor:   Chinese University of Hong Kong
  Not yet recruiting
• Evaluation of Acute Post-thrombectomy Complications for Stroke

  NCT04197830

  Conditions:   Stroke, Complication;   Stroke, Acute;   Stroke Hemorrhagic
  Intervention:   Procedure: Thrombectomy for stroke
  Sponsor:   University of Liege
  Not yet recruiting
• A Single Dose Escalation Study of PCSK9 Inhibitor (JS002) in Health Subjects

  NCT04197817

  Condition:   Hypercholesterolemia
  Interventions:   Drug: JS002;   Drug: Placebo
  Sponsor:   Shanghai Junshi Bioscience Co., Ltd.
  Completed
• Do Mirror Neurons Play a Role in Tourette Syndrome Physiopathology? A Pilot Study.

  NCT04197804

  Condition:   Tourette Syndrome
  Intervention:   Other: Routine tests perform
  Sponsor:   Istituto Ortopedico Galeazzi
  Completed
• Effect of Core Stabilization Exercises and Neuromuscular Electrical Stimulation in Patients With Idiopathic Pulmonary Fibrosis

  NCT04197791

  Condition:   Idiopathic Pulmonary Fibrosis
  Interventions:   Device: Neuromuscular Electrical Stimulation;   Other: Core Stabilization Exercises
  Sponsor:   Istanbul University-Cerrahpasa
  Active, not recruiting
• Food Effect Study of DDO-3055 Tablets in Healthy Subjects

  NCT04197778

  Condition:   Anemia in Chronic Kidney Disease
  Intervention:   Drug: DDO-3055 tablet
  Sponsor:   Jiangsu HengRui Medicine Co., Ltd.
  Not yet recruiting
• acTBS Treatment for Inpatient Subjects With Suicidality

  NCT04197765

  Condition:   Suicidality
  Intervention:   Device: accelerated Thetaburst stimulation
  Sponsor:   University of California, Los Angeles
  Not yet recruiting
• Regional Anesthesia and Analgesia Techniques in Obese Patients

  NCT04197752

  Conditions:   Obesity;   Regional Anesthesia
  Intervention:   Other: Regional anesthesia/analgesia techniques
  Sponsor:   Istanbul University
  Recruiting
• Fixed-dose Amikacin for Elderly UTI

  NCT04197739

  Conditions:   Urinary Tract Infections;   Elderly Infection
  Intervention:   Drug: Amikacin
  Sponsor:   Rabin Medical Center
  Not yet recruiting
• Glycaemic Response to High REsistant STarch Bread

  NCT04197726

  Condition:   Blood Glucose Response
  Interventions:   Other: sbeIIa/b white bread;   Other: Control white bread
  Sponsors:   Quadram Institute Bioscience;   Norfolk and Norwich University Hospitals NHS Foundation Trust
  Not yet recruiting
• Testing the Sequential Combination of the Anti-cancer Drugs Olaparib Followed by Adavosertib (AZD1775) in Patients With Advanced Solid Tumors With Selected Mutations and PARP Resistance, STAR Study

  NCT04197713

  Conditions:   Advanced Malignant Solid Neoplasm;   Metastatic Malignant Solid Neoplasm;   Refractory Malignant Solid Neoplasm;   Unresectable Malignant Solid Neoplasm
  Interventions:   Drug: Adavosertib;   Drug: Olaparib
  Sponsor:   National Cancer Institute (NCI)
  Not yet recruiting
• The PRESSURE CABG Cardiac Surgery Trial

  NCT04197700

  Conditions:   Coronary Artery Bypass Grafting;   Hypotension
  Intervention:   Other: Target MAP Management
  Sponsors:   University of Alberta;   Canadian VIGOUR Centre
  Not yet recruiting
• TPIV100 and Sargramostim for the Treatment of HER2 Positive, Stage II-III Breast Cancer in Patients With Residual Disease After Chemotherapy and Surgery

  NCT04197687

  Conditions:   Breast Adenocarcinoma;   Stage II Breast Cancer AJCC v6 and v7;   Stage IIA Breast Cancer AJCC v6 and v7;   Stage IIB Breast Cancer AJCC v6 and v7;   Stage III Breast Cancer AJCC v7;   Stage IIIA Breast Cancer AJCC v7;   Stage IIIB Breast Cancer AJCC v7;   Stage IIIC Breast Cancer AJCC v7
  Interventions:   Biological: Pertuzumab;   Other: Placebo Administration;   Biological: Sargramostim;   Biological: Trastuzumab;   Biological: Trastuzumab Emtansine;   Biological: Vaccine Therapy
  Sponsors:   Mayo Clinic;   National Cancer Institute (NCI)
  Not yet recruiting
• China Q Cohort Study

  NCT04197674

  Conditions:   End Stage Renal Disease on Dialysis;   Peritoneal Dialysis;   Hemodialysis
  Intervention:   Other: Dialysis modality
  Sponsor:   Sun Yat-sen University
  Not yet recruiting
• Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Healthy Elderly Subjects

  NCT04197661

  Condition:   Healthy Elderly Subjects
  Intervention:   Drug: HSK3486
  Sponsors:   Sichuan Haisco Pharmaceutical Group Co., Ltd.;   First Hospital of Jilin University
  Not yet recruiting
• Effects of Exercise on Thoracic Aneurysms

  NCT04197648

  Condition:   Aneurysms and Exercise
  Intervention:   Device: Exercise group
  Sponsor:   Paul Poirier
  Not yet recruiting
• Short-term Effects of Dapagliflozin on Peak VO2 in HFrEF

  NCT04197635

  Conditions:   Heart Failure With Reduced Ejection Fraction;   Type 2 Diabetes
  Interventions:   Diagnostic Test: Maximal functional capacity by cardiopulmonary exercise testing;   Diagnostic Test: Echocardiography;   Behavioral: Evaluation of quality of life health related;   Diagnostic Test: Submáximal functional capacity assesment by 6 minutes walk test
  Sponsor:   Fundación para la Investigación del Hospital Clínico de Valencia
  Recruiting
• Generation of Biological Samples Positive to Hydrochlorothiazide for Anti-doping Control

  NCT04197622

  Condition:   Healthy Volunteers
  Intervention:   Drug: Hydrochlorothiazide
  Sponsor:   Parc de Salut Mar
  Completed
• Static Muscular Stretching for Treatment of Peripheral Arterial Disease

  NCT04197609

  Condition:   Peripheral Artery Disease
  Intervention:   Device: Dorsiflexion Splint
  Sponsors:   Mayo Clinic;   Florida State University, College of Medicine
  Not yet recruiting
• Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)

  NCT04197596

  Conditions:   Viral Infection;   Primary Immune Deficiency Disorder
  Intervention:   Biological: BK CTL
  Sponsors:   New York Medical College;   Children's Hospital of Philadelphia;   Medical College of Wisconsin;   Nationwide Children's Hospital
  Not yet recruiting
• DJUS Postmarket Registry

  NCT04197583

  Condition:   Ureter Obstruction
  Intervention:   Device: Double-J Ureteral Stent
  Sponsor:   Boston Scientific Corporation
  Not yet recruiting
• OPIOID-FREE ANESTHESIA FOR OPEN CARDIAC SURGERY: A PROSPECTIVE RANDOMIZED CONTROLLED TRIAL

  NCT04197570

  Conditions:   Opioid Use;   Heart; Surgery, Heart, Functional Disturbance as Result;   Anesthesia
  Interventions:   Drug: Opioid Anesthetics;   Drug: Non Opioid Analgesics
  Sponsors:   Benaroya Research Institute;   Virginia Mason Hospital/Medical Center
  Not yet recruiting
• Bone Age of Chinese Child (BACC)

  NCT04197557

  Condition:   Bone Development
  Intervention:  
  Sponsors:   Beijing Jishuitan Hospital;   National Institute for Nutrition and Health Chinese Center for Disease Control and Prevention;   Beijing institute of child
  Recruiting
• Evaluation of the Implantation of the End-vascular Creation of the Arteriovenous Fistulas in Patients in the University Hospital of Araba. Pilot Study.

  NCT04197544

  Condition:   Efficacy and Safety
  Intervention:   Procedure: endoFAVI
  Sponsor:   Fernando López Zárraga
  Not yet recruiting
• Postoperative Pain After the Use of Different Last Irrigation Method During Root Canal Treatment in Primary Teeth

  NCT04197531

  Condition:   Post Operative Pain
  Intervention:   Other: Irrigation Method
  Sponsor:   TC Erciyes University
  Completed
• Evaluation the Neurocognitive Functions Among Children With Enlargement Adenoid and Tonsils, Before and After Tonsillectomy or Adenotonsillectomy

  NCT04197518

  Condition:   Child Neurocognitive Function
  Intervention:   Diagnostic Test: neuro trax system and a neurology test.
  Sponsor:   Hillel Yaffe Medical Center
  Not yet recruiting
• Application of Forward-looking Infrared for the Identification and Evaluation of Fractures in the Acute Trauma Setting

  NCT04197505

  Condition:   Acute Fracture
  Intervention:   Behavioral: FLIR E95 camera
  Sponsor:   NYU Langone Health
  Not yet recruiting
• Hypofractionated Stereotactic Radiotherapy With Anlotinib in Patients With Recurrent High-Grade Gliomas

  NCT04197492

  Condition:   Malignant Glioma
  Interventions:   Radiation: Hypofractionated Stereotactic Radiotherapy;   Drug: Anlotinib
  Sponsor:   Huashan Hospital
  Not yet recruiting
• A Study to Evaluate the Safety and Biomarkers of Resmetirom (MGL-3196) in Non Alcoholic Fatty Liver Disease (NAFLD) Patients

  NCT04197479

  Condition:   Non-Alcoholic Fatty Liver Disease
  Interventions:   Drug: Placebo;   Drug: Resmetirom
  Sponsor:   Madrigal Pharmaceuticals, Inc.
  Recruiting
• Comparison of Different Treatments for Overactive Bladder Syndrome

  NCT04197466

  Conditions:   Overactive Bladder;   Overactive Bladder Syndrome;   Overactive Detrusor
  Interventions:   Other: Pelvic Floor Exercise Group;   Other: Kinesio tape;   Other: Electrical stimulation
  Sponsor:   Ankara Yildirim Beyazıt University
  Recruiting
• The Cardiovascular Multi-dimensional Observational Investigation of the Use of PCSK9 Inhibitors (cvMOBIUS)

  NCT04197453

  Condition:   ASCVD
  Intervention:  
  Sponsors:   Amgen;   Duke Clinical Research Institute
  Recruiting
• Characterization of Bovine Adrenal Medulla (BAM8-22) as a New Surrogate Model of Non-histaminergic Itch

  NCT04197440

  Conditions:   BAM8-22;   SPT Pricks
  Interventions:   Drug: BAM8-22 2mg/ml;   Drug: BAM8-22 1mg/ml;   Drug: BAM8-22 0.5 mg/ml;   Drug: Placebo;   Drug: BAM8-22 with 1 SPT;   Drug: BAM8-22 with 5 SPT;   Drug: BAM8-22 with 25 SPT;   Drug: BAM8-22 with inactivate cowhage spicules
  Sponsor:   Aalborg University
  Not yet recruiting
• Determination of the Safety and Efficacy of a Novel Oral Rinse on Oral Health

  NCT04197427

  Conditions:   Plaque;   Gingivitis
  Interventions:   Device: Experimental Oral Rinse;   Device: Placebo
  Sponsor:   You First Services
  Not yet recruiting
• Development of Urologic Registry for Personalized Medicine in Patients With Urological Malignancy by Analyzing Circulating Tumor DNA

  NCT04197414

  Conditions:   Prostate Cancer;   Renal Cell Cancer;   Bladder Cancer;   Ureter Cancer
  Intervention:  
  Sponsor:   Yonsei University
  Recruiting
• Screening & Health Education in Barbershops Centers for Hypertension

  NCT04197401

  Condition:   Hypertension
  Intervention:  
  Sponsors:   Dacima Consulting;   Société Tunisienne de Cardiologie & de Chirurgie Cardiovasculaire
  Completed
• Inspiratory Muscle Training in Pulmonary Arterial Hypertension

  NCT04197388

  Condition:   Pulmonary Hypertension
  Intervention:   Device: Inspiratory muscle training device
  Sponsor:   Golden Jubilee National Hospital
  Recruiting
• Impact of Pre-cooling in Adolescent Tennis Athletes

  NCT04197375

  Condition:   Risk of Heat Stress
  Interventions:   Behavioral: Thermal stress and performance using a pre-cooling protocol;   Biological: Thermal stress and performance without a pre-cooling protocol
  Sponsor:   Petros Dinas
  Completed
• Everyday Activity Shoes: a Quantification of Impact Forces While Walking

  NCT04197362

  Condition:   Impact Forces
  Intervention:   Other: Evaluation
  Sponsor:   Emory University
  Not yet recruiting
• Safety, Tolerability and Pharmacokinetics of ALD1910 in Healthy Men and Woman

  NCT04197349

  Condition:   Migraine
  Interventions:   Biological: ALD1910;   Biological: Sumatriptan
  Sponsors:   H. Lundbeck A/S;   Alder Biopharmaceuticals, Inc.
  Recruiting
• Bariatric Embolization of Arteries With Imaging Visible Embolics (BEATLES)

  NCT04197336

  Conditions:   Obesity;   Morbid Obesity;   Weight Loss
  Interventions:   Device: Bariatric Embolization of Arteries with imaging visible Embolics;   Other: Control Arm
  Sponsors:   Johns Hopkins University;   Biocompatibles UK Ltd
  Not yet recruiting
• Alprostadil Liposomes for Injection for Lower Extremity Arteriosclerosis Obliteran of Phase II Clinical Trial

  NCT04197323

  Condition:   Peripheral Artery Disease
  Intervention:   Drug: Alprostadil liposomes for injection
  Sponsor:   CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
  Recruiting
• Cabozantinib and Nivolumab for Carcinoid Tumors

  NCT04197310

  Conditions:   Carcinoid Tumor;   Carcinoid Tumor of GI System;   Neuroendocrine Tumors
  Interventions:   Drug: Nivolumab;   Drug: Cabozantinib
  Sponsors:   Dana-Farber Cancer Institute;   Bristol-Myers Squibb;   Exelixis
  Not yet recruiting
• Brain Imaging Biomarkers in Patients With Brain Metastasis

  NCT04197297

  Condition:   Brain Metastases, Adult
  Intervention:   Diagnostic Test: CT and MRI Scans
  Sponsor:   University Health Network, Toronto
  Not yet recruiting
• Determination of the Effectiveness of Certain Physical Methods in the Treatment of Knee Osteoarthritis

  NCT04197284

  Condition:   Osteoarthritis, Knee
  Interventions:   Device: Biofeedback, Myomed 632;   Device: device for electrical stimulation, BTL 4000 Smart;   Other: kinesitherapy
  Sponsor:   Clinical Hospital Centre Zagreb
  Not yet recruiting
• Management of Acutely Symptomatic Hernia

  NCT04197271

  Conditions:   Hernia;   Emergencies;   Surgery--Complications
  Interventions:   Procedure: Emergency Hernia Repair;   Other: Conservative management
  Sponsor:   Sheffield Teaching Hospitals NHS Foundation Trust
  Not yet recruiting
• Evaluation of the Impact of an Individual Peer Support Intervention for Stroke Patients When Returning Home: a Mixed Methods Pilot Study

  NCT04197258

  Condition:   Stroke
  Intervention:   Other: Peer support
  Sponsor:   Hospices Civils de Lyon
  Not yet recruiting
• Efficacy of Saline Injection Therapy in Atrophic Acne Scars

  NCT04197245

  Conditions:   Atrophic;   Scars
  Intervention:   Drug: saline injection therapy in post-acne atrophic scars
  Sponsor:   Jinnah Postgraduate Medical Centre
  Completed
• Study on the Safety for the Newborn of the Use of Biologics During Pregnancy by Mothers Affected by Autoimmune Diseases

  NCT04197232

  Condition:   Suspected Damage to Fetus From Biologic Agents
  Intervention:   Other: clinical evaluation
  Sponsor:   IRCCS San Raffaele
  Recruiting
• Pembrolizumab With Axitinib in Recurrent Endometrial Cancer

  NCT04197219

  Condition:   Recurrent Endometrial Cancer
  Interventions:   Drug: Pembrolizumab;   Drug: Axitinib
  Sponsor:   Haider Mahdi
  Not yet recruiting
• Ultrasound Guided Costotransverse Block for Breast Cancer Surgery

  NCT04197206

  Condition:   Postoperative Pain
  Intervention:   Other: costotransverse block
  Sponsor:   Cigli Regional Training Hospital
  Not yet recruiting
• Monitoring Antioxidant/Redox Status at Concordia (MARS-C)

  NCT04197193

  Condition:   Oxidative Stress
  Intervention:  
  Sponsors:   University of Southampton;   European Space Agency
  Not yet recruiting
• Hybrid APC for Gastric Low Grade Intraepithelial Neoplasia

  NCT04197180

  Condition:   Gastric Low Grade Intraepithelial Neoplasia
  Intervention:   Procedure: Hybrid Argon Plasma Coagulation
  Sponsors:   Chinese University of Hong Kong;   Nanfang Hospital of Southern Medical University;   Shenzhen Hospital of Southern Medical University;   The Fifth Affiliated Hospital of Zunyi Medical University, Zhuhai, China
  Not yet recruiting
• Mid-Infrared Spectroscopy as a Real Time Diagnostic Tool for Chronic Endometritis

  NCT04197167

  Conditions:   Endometritis;   IVF
  Interventions:   Procedure: Hysteroscopy;   Device: Infrared Spectroscopy
  Sponsor:   Hillel Yaffe Medical Center
  Not yet recruiting
• Pain-related Fear as a Facilitator of Nocebo Hyperalgesia

  NCT04197154

  Conditions:   Hyperalgesia;   Chronic Pain Syndrome;   Chronic Pain, Psychogenic;   Fear of Pain
  Interventions:   Behavioral: Threat manipulation (control, no threat);   Behavioral: Threat manipulation;   Behavioral: Conditioning of moderate pain;   Behavioral: Conditioning of high pain;   Behavioral: Extinction
  Sponsors:   Leiden University Medical Center;   Universiteit Leiden;   KU Leuven;   Maastricht University
  Recruiting
• Hypofractionated Whole-Pelvis Radiotherapy (WPRT) vs Conventionally-Fractionated WPRT in Prostate Cancer

  NCT04197141

  Condition:   Prostate Cancer
  Interventions:   Radiation: Conventionally-fractionated WPRT;   Radiation: Hypofractionated WPRT
  Sponsors:   Lawson Health Research Institute;   Canadian Association of Radiation Oncology;   AbbVie
  Not yet recruiting
• Lateral Ridge Augmentation Around Implants

  NCT04197128

  Condition:   Alveolar Bone Resorption
  Interventions:   Device: Resorbable Collagen membrane with bone graft for augmentation;   Device: Ribose cross linked collagen matrix for augmentation
  Sponsor:   Krishnadevaraya College of Dental Sciences & Hospital
  Recruiting
• Vitamin C, Thiamine, Cyanocobalamine, Pyridoxine and Hydrocortisone in Sepsis

  NCT04197115

  Conditions:   Sepsis;   Septic Shock
  Interventions:   Drug: Vitamin C;   Drug: Hydrocortisone;   Drug: Complex B
  Sponsor:   IMSS Hospital General de Zona 11, Piedras Negras
  Recruiting
• Use of CBD Oil in the Treatment of Posttraumatic Stress Disorder

  NCT04197102

  Condition:   Post Traumatic Stress Disorder
  Interventions:   Drug: Cannabidiol (CBD) oil;   Behavioral: Trauma focused group cognitive-behavioral therapy (CBT);   Other: Placebo oil
  Sponsor:   University of Texas at Austin
  Recruiting
• Biological Effect of Vitamin D in Patients With Urothelial Carcinoma

  NCT04197089

  Condition:   Urothelial Carcinoma
  Intervention:   Drug: Vitamin D
  Sponsors:   Germans Trias i Pujol Hospital;   Spanish Clinical Research Network - CAIBER;   Centro Nacional de Investigaciones Oncologicas CARLOS III;   Fundació Institut Germans Trias i Pujol
  Not yet recruiting
• Neoadjuvant Therapy in Resectable Non-Small Cell Lung Cancer Stages IIIA

  NCT04197076

  Condition:   Non Small Cell Lung Cancer
  Interventions:   Drug: anti-PD-1 or anti-PD-L1;   Drug: EGFR-TKI, ALK inhibitor, ROS1 inhibitor;   Drug: investigator decided
  Sponsor:   Shanghai Chest Hospital
  Recruiting
• Sugar-Sweetened Beverage Portion Limit Study

  NCT04197063

  Condition:   Health Policy
  Intervention:   Behavioral: Sweetened beverage portion size limit
  Sponsor:   Rutgers, The State University of New Jersey
  Completed
• Effect of Sacubitril/Valsartan on Reduced Right Ventricular Ejection Fraction in Patients With CTD

  NCT04197050

  Conditions:   Myocardial Injury;   Connective Tissue Diseases
  Intervention:   Drug: Sacubitril / Valsartan Oral Tablet
  Sponsor:   RenJi Hospital
  Not yet recruiting
• Prevalence of Sialorrhea in Patients Treated With Clozapine

  NCT04197037

  Conditions:   Sialorrhea;   Clozapine Adverse Reaction;   Quality of Life
  Intervention:   Procedure: Evaluation of sialorrhea through questionnaires that measure daytime and nighttime sialorrhea and the impact on quality of life.
  Sponsor:   Parc de Salut Mar
  Recruiting
• Assessment of Exercise Capacity in Virtual Reality

  NCT04197024

  Condition:   COPD
  Interventions:   Device: Exercise capacity test;   Device: Exercise capacity test in virtual reality
  Sponsor:   The Opole University of Technology
  Not yet recruiting
• Advanced Prosthetic Devices for Lower Limb Amputees

  NCT04197011

  Condition:   Prostheses and Implants
  Intervention:   Device: prosthetic device
  Sponsor:   Nottingham Trent University
  Recruiting
• Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Hepatitis b Virus Related Compensated Cirrhosis

  NCT04196998

  Conditions:   Hepatitis B;   Compensated Cirrhosis
  Interventions:   Drug: Entecavir;   Drug: Tenofovir Disoproxil Fumarate;   Drug: Tenofovir alafenamide
  Sponsor:   Third Affiliated Hospital, Sun Yat-Sen University
  Recruiting
• FDG PET/CT Versus PET/MRI in Detecting Locoregional Recurrence 3 Months After CRT in Head and Neck SCC

  NCT04196985

  Condition:   Head and Neck Squamous Cell Carcinoma
  Interventions:   Diagnostic Test: PET/MRI;   Diagnostic Test: PET/TT
  Sponsor:   Turku University Hospital
  Not yet recruiting
• Telementoring Intervention (ECHO) for the Transformation of Professional Engagement, Practice Efficiency, and Community Building Through Team Meetings in Diagnostic Imaging Clinicians

  NCT04196972

  Condition:   Malignant Neoplasm
  Interventions:   Other: Communication Intervention;   Other: Questionnaire Administration;   Other: Waiting List
  Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI)
  Not yet recruiting
• Evaluation of TYR Sphere

  NCT04196959

  Conditions:   Tyrosinemias;   Alkaptonuria;   Tyrosinemia, Type I;   Tyrosinemia, Type II;   Tyrosinemia, Type III
  Intervention:   Dietary Supplement: TYR sphere
  Sponsor:   Vitaflo International, Ltd
  Recruiting
• Use of Intrathecal Analgesia in Appendectomy

  NCT04196946

  Conditions:   Anesthesia;   Analgesia
  Interventions:   Drug: 25 mcg fentanyl;   Drug: 250 mcg alfentanil
  Sponsor:   Nigde Omer Halisdemir University
  Completed
• Analysis of Vestibular Compensation Following Vestibular Neurectomy

  NCT04196933

  Conditions:   Migraine;   Vestibular Migraine;   Vestibular Schwannoma;   Motion Sickness;   Dizziness;   Vestibular Disorder
  Interventions:   Behavioral: Temporal Binding Adaptation - TBW training;   Behavioral: Temporal Binding Adaptation - PSS training;   Behavioral: Temporal Binding Adaptation - PSS adaptation with VI stimulation;   Behavioral: Chronic Motion-modulated Stimulation
  Sponsors:   Massachusetts Eye and Ear Infirmary;   National Institute on Deafness and Other Communication Disorders (NIDCD);   Oregon Health and Science University;   University of Geneva, Switzerland
  Enrolling by invitation
• Methotrexate-associated Anti-TNF Combination Therapy, the Neglected One !

  NCT04196920

  Condition:   Chronic Inflammatory Bowel Disease
  Intervention:  
  Sponsors:   University Hospital, Montpellier;   Rennes University Hospital - CHU Pontchaillou
  Not yet recruiting
• [Trial of device that is not approved or cleared by the U.S. FDA]

  NCT04196907

  Condition:  
  Intervention:  
  Sponsor:   [Redacted]
  Withheld
• Ischemic Stroke, Obesity and Thrombolysis

  NCT04196894

  Condition:   Ischemic Stroke
  Intervention:  
  Sponsor:   University Hospital Inselspital, Berne
  Recruiting
• Effect of Attention Deficit Hyperactivity Disorder Knowledge Improvement Program on Male Primary School Teachers

  NCT04196881

  Conditions:   ADHD;   Mental Disorder;   Attention Deficit Hyperactivity Disorder
  Intervention:   Other: Knowledge Improvement Program about ADHD
  Sponsor:   King Khalid University
  Active, not recruiting
• Methotrexate and Metformin in Rheumatoid Arthritis Patients

  NCT04196868

  Condition:   Arthritis, Rheumatoid
  Interventions:   Drug: Metformin treatment;   Other: Placebo;   Drug: Methotrexate treatment
  Sponsors:   University Hospital, Bordeaux;   Ministry for Health and Solidarity, France
  Not yet recruiting
• Study of Teriparatide in Stress Fracture Healing

  NCT04196855

  Conditions:   Stress Fracture;   Parathyroid Hormone
  Intervention:   Drug: Teriparatide
  Sponsors:   University of East Anglia;   Ministry of Defence, United Kingdom;   Darlington Memorial Hospital;   Clinical Research and Trials Unit (Norfolk & Norwich University Hospital, UK)
  Not yet recruiting
• Heart Failure Precision Medicine Study

  NCT04196842

  Condition:   Heart Failure
  Intervention:   Device: Telemonitoring devices
  Sponsor:   University of California, Davis
  Recruiting