JoinClinicalTrials.com

• Improving Safety of Lead Extraction Procedures by Traction Force Sensing

  NCT03842124

  Conditions:   Cardiac Implantable Electronic Device Infection;   Cardiovascular Infections
  Intervention:   Other: Force gauge
  Sponsor:   Mayo Clinic
  Recruiting
• Does Whole Blood Adsorber During CPB Reduce Vasoactive Drugs Postoperatively in Endocarditis Patients Undergoing Valve Surgery?

  NCT03945708

  Condition:   Infective Endocarditis
  Intervention:   Device: CytoSorb
  Sponsors:   Emma Hansson;   CytoSorbents, Inc
  Recruiting
• Stroke-free Survival Comparison Between Early Surgery and Conventional Therapy in Left Infective Endocarditis

  NCT03411499

  Condition:   Endocarditis
  Interventions:   Procedure: Early surgery;   Procedure: Conventional therapy
  Sponsors:   Maria Vittoria Hospital;   Ministry of Health, Italy
  Recruiting
• Vancomycin, Gentamycin in Infective Endocarditis

  NCT03688659

  Condition:   Infective Endocarditis
  Intervention:   Drug: Vancomycin and gentamycin
  Sponsor:   Assiut University
  Not yet recruiting
• Characterization of RadiOlabeled Tracer Uptake Pattern in Noninfected Transcatheter Aortic Valves.

  NCT03683355

  Condition:   Infective Endocarditis
  Intervention:   Radiation: 18F-FDG PET/CT
  Sponsor:   Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
  Recruiting
• PET/MR Imaging In Patients With Infective Endocarditis

  NCT03626571

  Condition:   Infective Endocarditis
  Intervention:   Other: 18F-FDG
  Sponsor:   University of Edinburgh
  Recruiting
• Detection of the Most Common Microorganism of Infective Endocarditis in Assiut University Hospital

  NCT03487653

  Condition:   Infective Endocarditis
  Intervention:   Biological: microbiology:Blood culture and sensitvity test .Serology
  Sponsor:   Safaa Samir
  Not yet recruiting
• Evaluation of a Metabolic Preparation by a Low-carbohydrate Diet as Atkins-diet to Help in Detecting Infective Endocarditis by 18F-FDG PET

  NCT03465098

  Condition:   Infective Endocarditis
  Intervention:   Other: Strict low carbohydrate diet (< 3gr/day of carbohydrate) before a 18F-FDG PET/CT
  Sponsor:   Central Hospital, Nancy, France
  Not yet recruiting
• French National Observatory on Infective Endocarditis

  NCT03272724

  Condition:   Infective Endocarditis
  Intervention:  
  Sponsors:   Central Hospital, Nancy, France;   Bichat Hospital;   Centre Hospitalier Universitaire de Pointe-a-Pitre;   Centre Hospitalier Universitaire de Besancon;   Hospices Civils de Lyon;   University Hospital, Montpellier;   Rennes University Hospital;   Hôpital Saint André, Reims
  Recruiting
• Hemoadsorption for Prevention of Vasodilatory Shock in Cardiac Surgery Patients With Infective Endocarditis

  NCT03266302

  Condition:   Infective Endocarditis
  Intervention:   Device: hemoadsorber for removal of cytokines
  Sponsors:   Jena University Hospital;   CytoSorbents, Inc;   Thermo Fisher Scientific;   Fraunhofer Institute for Interfacial Engineering and Biotechnology;   German Federal Ministry of Education and Research
  Recruiting
• Cytokine REmoval in CRitically Ill pAtients Requiring Surgical Therapy for Infective Endocarditis (RECReATE)

  NCT03892174

  Conditions:   Endocarditis;   Sepsis;   Septic Shock
  Intervention:   Other: Treatment protocol with adsorption
  Sponsor:   University Hospital Inselspital, Berne
  Recruiting
• Oral Switch During Treatment of Left-sided Endocarditis Due to Multi-susceptible Staphylococcus

  NCT02701608

  Condition:   Infective Endocarditis
  Interventions:   Drug: Levofloxacin;   Drug: Rifampicin;   Procedure: Conventional IV treatment of staphylococci IE following European guidelines 2015 including cloxacilline, oxacilline,gentamicine,vancomycine,rifampicine
  Sponsor:   University Hospital, Tours
  Recruiting
• Oral Switch During Treatment of Left-sided Endocarditis Due to Multi-susceptible Streptococcus

  NCT02701595

  Condition:   Infective Endocarditis
  Interventions:   Drug: Amoxicillin;   Procedure: Conventional IV treatment of streptococci/enterococci IE following European guidelines 2015 including amoxicillin, gentamicin, amicillin, vancomycin, penicillin G, ceftriaxone, netilmicin
  Sponsor:   University Hospital, Tours
  Recruiting
• Effect of Dexmedetomidine on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery

  NCT02698930

  Condition:   Infective Endocarditis
  Interventions:   Drug: dexmedetomidine;   Drug: Normal saline
  Sponsor:   Yonsei University
  Recruiting
• Endocarditis Registry of the University Hospital of Cologne (ER-UHC)

  NCT02388893

  Condition:   Infective Endocarditis
  Intervention:  
  Sponsor:   University of Cologne
  Recruiting
• Study of the Prognosis of Infectious Endocarditis (EPEI)

  NCT03211975

  Condition:   Endocarditis Infective
  Intervention:   Other: To study the evolution of the prognosis of infectious endocarditis on native valves and on prostheses
  Sponsor:   Centre Hospitalier Universitaire, Amiens
  Recruiting
• Contribution of 18F-FDG PET-CT in the Diagnosis and the Detection of Peripheral Emboli of Infectious Endocarditis on Native Valves

  NCT03695861

  Condition:   Endocarditis
  Intervention:   Diagnostic Test: Whole-body 18F-FDG PET-CT scan
  Sponsor:   University Hospital, Bordeaux
  Not yet recruiting
• Predisposition to Infectious Endocarditis

  NCT03979261

  Condition:   Infective Endocarditis
  Intervention:   Diagnostic Test: evolution of sex ratio according to age
  Sponsor:   Assistance Publique Hopitaux De Marseille
  Not yet recruiting
• Accelerated Treatment of Endocarditis

  NCT03851575

  Condition:   Infectious Endocarditis
  Interventions:   Other: Accelerated treatment of endocarditis;   Other: Usual guideline therapy
  Sponsors:   Rigshospitalet, Denmark;   Herlev Hospital;   Nordsjaellands Hospital;   Zealand University Hospital;   Odense University Hospital;   Aarhus University Hospital;   Lund University Hospital
  Recruiting
• Management of Infectious Endocarditis as Part of a Multidisciplinary Consensus Meeting

  NCT03429153

  Condition:   Endocarditis
  Intervention:  
  Sponsor:   University Hospital, Strasbourg, France
  Recruiting
• Fosfomycin i.v. for Treatment of Severely Infected Patients

  NCT02979951

  Conditions:   Bacterial Infections;   Bone Diseases, Infectious;   Osteomyelitis;   Central Nervous System Bacterial Infections;   Meningitis, Bacterial;   Encephalitis;   Brain Abscess;   Urinary Tract Infections;   Respiratory Tract Infections;   Pneumonia, Bacterial;   Skin Diseases, Bacterial;   Soft Tissue Infections;   Intraabdominal Infections;   Sepsis;   Bacteremia;   Endocarditis, Bacterial
  Intervention:  
  Sponsors:   Infectopharm Arzneimittel GmbH;   INPADS GmbH;   Dr. Oestreich + Partner GmbH
  Recruiting
• Impact of the Blood Culture Technique on the Diagnosis of Infective Endocarditis

  NCT03153384

  Conditions:   Bacteremia;   Infective Endocarditis
  Intervention:   Procedure: Blood Culture
  Sponsor:   Central Hospital, Nancy, France
  Not yet recruiting
• Early Valve Surgery Versus Conventional Treatment in Infective Endocarditis Patients With High Risk of Embolism

  NCT03718052

  Condition:   Endocarditis
  Interventions:   Procedure: Early valve surgery (EVS);   Procedure: Conventional Care
  Sponsor:   Assistance Publique - Hôpitaux de Paris
  Recruiting
• Cardiac Surgery Peer Recovery Support Program

  NCT03590106

  Conditions:   IV Drug Usage;   Infective Endocarditis;   Substance Use Disorders
  Intervention:   Behavioral: Peer Recovery Support Program
  Sponsor:   University of Rochester
  Recruiting
• Effect of PCSK9 Inhibition on Cardiovascular Risk in Treated HIV Infection (EPIC-HIV Study)

  NCT03207945

  Conditions:   Dyslipidemias;   Cardiovascular Diseases;   HIV Infections
  Interventions:   Drug: Alirocumab;   Other: Placebo
  Sponsors:   University of California, San Francisco;   Massachusetts General Hospital
  Recruiting
• Scrub Typhus Infection Induced Cardiovascular Disease

  NCT03274869

  Conditions:   Scrub Typhus;   Cardiovascular Complication
  Intervention:   Other: No intervention
  Sponsors:   Eulji University Hospital;   Chungnam National University Hospital;   Chungbuk National University Hospital
  Recruiting
• Impact of Endothelial and Leukocyte Senescence in Circulatory Shock States

  NCT03559569

  Conditions:   Shock;   Cardiovascular Diseases;   Infection
  Intervention:   Biological: Biological samples will be done to evaluate the endothelial and leukocyte senescence.
  Sponsor:   University Hospital, Strasbourg, France
  Recruiting
• Influence of Freeze Dried Strawberry Consumption on Gut Microbiota and Cardiovascular Health.

  NCT03283969

  Conditions:   Microbial Colonization;   Cardiovascular Diseases;   Obesity
  Interventions:   Other: Freeze Dried Strawberry Powder;   Other: Isocaloric powder
  Sponsor:   University of California, Davis
  Recruiting
• Drug-drug Interactions Between Antiretroviral Drugs and Cardiovascular Drugs in Elderly Patients

  NCT03515772

  Conditions:   HIV Infections;   Drug Interactions;   Cardiovascular Diseases
  Intervention:   Drug: Co-administration of darunavir with a cardiovascular drug
  Sponsor:   Centre Hospitalier Universitaire Vaudois
  Recruiting
• Effect of Heroin Use on Immune Activation and Cardiovascular Risk in HIV

  NCT03976258

  Conditions:   HIV Infection;   Opioid-use Disorder;   Cardiovascular Diseases
  Interventions:   Drug: buprenorphine/naloxone;   Drug: Methadone;   Drug: Naltrexone Injection;   Drug: Heroin
  Sponsors:   MetroHealth Medical Center;   National Institute on Drug Abuse (NIDA)
  Recruiting
• Lipid Profile and Diabetes Mellitus in People With HIV

  NCT04125784

  Conditions:   HIV Infections;   Dyslipidemias;   Diabetes Mellitus;   Cardiovascular Risk Factor
  Intervention:  
  Sponsors:   Igor Grabovac;   Merck Gesellschaft mbH, Austria
  Not yet recruiting
• CD24Fc Administration to Decrease LDL and Inflammation in HIV Patients (CALIBER)

  NCT03960541

  Conditions:   HIV Infections;   Dyslipidemias
  Interventions:   Drug: CD24Fc (human CD24 extracellular domain and human IgG1 Fc fusion protein);   Drug: Saline Solution
  Sponsors:   OncoImmune, Inc.;   University of Maryland, Baltimore;   National Heart, Lung, and Blood Institute (NHLBI)
  Recruiting
• 'The Impact of Rhinovirus Infections in Paediatric Cardiac Surgery'

  NCT02438293

  Conditions:   Rhinovirus;   Congenital Heart Disease;   Respiratory Infections;   Post-operative Complications
  Intervention:   Other: rhinovirus diagnostics
  Sponsor:   Leiden University Medical Center
  Recruiting
• t-PA Prophylaxis to Prevent Catheter-associated Thrombosis and Infection

  NCT03672006

  Conditions:   Central Venous Catheter Thrombosis;   Central Venous Catheter Associated Bloodstream Infection
  Interventions:   Biological: alteplase (recombinant t-PA);   Drug: Heparin
  Sponsor:   Medical College of Wisconsin
  Recruiting
• Prospective Urban Rural Epidemiology Study

  NCT03225586

  Conditions:   Cardiovascular Diseases;   Risk Factor, Cardiovascular;   Health Behavior;   Environmental Exposure;   Lung Diseases;   Cancer;   Injuries;   Renal Disease;   Communicable Disease
  Intervention:  
  Sponsors:   Population Health Research Institute;   Canadian Institutes of Health Research (CIHR);   Heart and Stroke Foundation of Ontario
  Recruiting
• Northern Sweden Health and Disease Study

  NCT03426488

  Conditions:   Cardiovascular Diseases;   Cancer;   Neurodegenerative Diseases;   Respiratory Disease;   Infection
  Intervention:   Behavioral: VIP - Västerbotten Intervention Programme
  Sponsor:   Umeå University
  Recruiting
• PREDICT 2: Personalized Responses to Dietary Composition Trial 2

  NCT03983733

  Conditions:   Diabetes;   Heart Diseases;   Diet Habit;   Diet Modification;   Microbial Colonization;   Healthy;   Obesity;   Metabolism
  Intervention:   Other: Dietary Intervention
  Sponsors:   Zoe Global Limited;   Massachusetts General Hospital;   Stanford University;   King's College London;   Tufts University
  Recruiting
• Personalised Responses to Dietary Composition Trial

  NCT03479866

  Conditions:   Diabetes;   Heart Diseases;   Diet Habit;   Diet Modification;   Microbial Colonization;   Healthy;   Obesity;   Metabolism
  Intervention:   Other: Dietary intervention
  Sponsors:   Guy's and St Thomas' NHS Foundation Trust;   King's College London;   Massachusetts General Hospital
  Recruiting
• Cardiovascular Disease in HIV and Hepatitis C: Risk Outcomes After Hepatitis C Eradication

  NCT03823911

  Conditions:   Cardiovascular Diseases;   Hepatitis C;   Hiv
  Interventions:   Drug: Elbasvir / Grazoprevir Oral Tablet [Zepatier];   Procedure: Cardiac MRI
  Sponsors:   University of Maryland, College Park;   National Institutes of Health (NIH);   Merck Sharp & Dohme Corp.
  Recruiting
• PIcc Cost EffectiveneSS and Safety of Infusional Therapy

  NCT03392831

  Conditions:   Thrombosis;   Infection
  Interventions:   Other: Peripherally inserted central catheter (PICC);   Other: Central venous catheter
  Sponsor:   Hospital de Clinicas de Porto Alegre
  Not yet recruiting
• Respiratory Virus Infections in Acutely Hospitalized Adult Patients With Pulmonary and Extrapulmonary Complications

  NCT03816059

  Conditions:   Respiratory Virus Infection;   Stroke;   Lung Disease;   Acute Coronary Syndrome
  Intervention:   Diagnostic Test: Respiratory virus testing
  Sponsor:   The University of Hong Kong
  Recruiting
• 2000 HIV Human Functional Genomics Partnership Program

  NCT03994835

  Condition:   HIV Infections
  Intervention:  
  Sponsors:   Radboud University;   ViiV Healthcare;   Elisabeth-TweeSteden Ziekenhuis;   Erasmus Medical Center;   Onze Lieve Vrouwe Gasthuis
  Not yet recruiting
• Taurolock Hep 500 Versus Unfractionated Heparin as Anti-inflammatory in Hemodialysis Catheters.

  NCT03539718

  Conditions:   Hemodialysis Catheter Infection;   Thrombosis; Dialysis Catheter
  Interventions:   Drug: Taurolidine heparin;   Drug: Heparin Sodium
  Sponsor:   Ain Shams University
  Recruiting
• Neutrolin Versus Heparin for Locking Hemodialysis Catheters

  NCT03425448

  Conditions:   Hemodialysis Catheter Infection;   Catheter Thrombosis
  Interventions:   Drug: Heparin;   Device: Neutrolin
  Sponsor:   King Abdullah International Medical Research Center
  Not yet recruiting
• Coxsackie Virus in Pregnancy and Congenital Heart Disease

  NCT03737006

  Condition:   Congenital Heart Disease in Pregnancy
  Intervention:  
  Sponsor:   Washington University School of Medicine
  Recruiting
• Cardiovascular Risk and Chronic Inflammatory Rheumatism

  NCT03187444

  Conditions:   Rheumatology;   Cardiovascular Diseases;   Arthritis, Rheumatoid;   Spondyloarthritis
  Intervention:   Procedure: Examinations
  Sponsor:   University Hospital, Clermont-Ferrand
  Recruiting
• A Study of the IJV or the SCV Approach for Ultrasound-guided Implantation of TIVAD

  NCT03945045

  Conditions:   Venous Thrombosis;   Catheter-Related Infections;   Catheter Mechanical Failure Rate
  Interventions:   Procedure: Subclavian vein approach;   Procedure: internal jugular vein approach
  Sponsor:   National Taiwan University Hospital
  Recruiting
• Peripherally Inserted Versus Centrally Inserted Central Venous Catheters in the Neurosurgical Intensive Care Unit

  NCT03908866

  Conditions:   Thromboses, Venous;   Infection;   Economic Problems
  Interventions:   Other: PICC(Peripherally inserted central catheter);   Other: CVC(Central venous catheter )
  Sponsor:   First Affiliated Hospital Xi'an Jiaotong University
  Recruiting
• Effectiveness of a Hydrophobic Dressing for Microorganisms' Colonization and Infection Control of Vascular Ulcers

  NCT03667937

  Conditions:   Venous Leg Ulcer;   Bacterial Infections;   Chronic Ulcer of Skin of Lower Limb Nos
  Interventions:   Combination Product: CUTIMED;   Other: AQUACEL silver
  Sponsors:   University of Malaga;   BSN Medical GmbH;   Andalusian Health Service
  Not yet recruiting
• High Intensity Lipid Lowering Following Acute Coronary Syndromes for Persons Living With HIV

  NCT02841774

  Conditions:   HIV Infection;   Coronary Heart Disease
  Interventions:   Drug: Pravastatin;   Drug: Rosuvastatin
  Sponsor:   Matthew Feinstein
  Recruiting
• Human and Bacterial Protease Activity as Prognostic Tool of Foot Infections in Diabetic Patients

  NCT03964571

  Condition:   Diabetic Foot Infection
  Intervention:   Diagnostic Test: WOUNDCHEK
  Sponsor:   Centre Hospitalier Universitaire de Nīmes
  Recruiting
• Effectiveness and Safety of Antibiotherapy in Diabetic Patients Treated for a Diabetic Foot Infection.

  NCT03495349

  Condition:   Diabetic Foot Infection
  Intervention:   Other: safety and effectiveness of the usual treatments of diabetic foot infections
  Sponsor:   Hospices Civils de Lyon
  Not yet recruiting
• Cardiovascular Function and Ribavirin Pharmacokinetics and Pharmacodynamics in Patients With Lassa Fever

  NCT03889106

  Condition:   Lassa Fever
  Intervention:   Drug: Ribavirin
  Sponsors:   University of Oxford;   National Institute for Health Research, United Kingdom;   Kenema Government Hospital;   London School of Hygiene and Tropical Medicine;   Public Health England
  Recruiting
• Optimal Antibiotics for Operated Diabetic Foot Infections

  NCT04081792

  Conditions:   Diabetic Foot Infection;   Surgical Wound;   Antibiotic Side Effect;   Infection
  Intervention:   Procedure: Antibiotic therapy
  Sponsor:   Balgrist University Hospital
  Recruiting
• Vaccination Against Influenza to Prevent Cardiovascular Events After Acute Coronary Syndromes

  NCT04001504

  Condition:   Acute Coronary Syndrome
  Interventions:   Biological: Double Dose Quadrivalent Influenza Vaccine;   Biological: Standard Dose Quadrivalent Influenza Vaccine
  Sponsors:   Hospital Israelita Albert Einstein;   Ministry of Health, Brazil
  Recruiting
• Standard Versus PICO Dressings in Lower-Extremity Bypass Patients

  NCT02492854

  Conditions:   Of Bypass Graft of the Extremities;   Peripheral Arterial Disease;   Vascular Diseases;   Cardiovascular Diseases
  Interventions:   Device: PICO Single-Use Negative Pressure Dressings;   Other: Sterile Gauze Dressings
  Sponsors:   Boston Medical Center;   Smith & Nephew, Inc.
  Recruiting
• Fungal Infection in Patients With Diabetic Foot Osteomyelitis

  NCT04041739

  Condition:   Diabetic Foot Osteomyelitis
  Intervention:   Diagnostic Test: fungal osteomyelitis culture and sensitivity
  Sponsor:   Assiut University
  Not yet recruiting
• Systems Analysis of Antigen Presenting Cells in Human Sepsis

  NCT03788772

  Conditions:   Sepsis;   Acute Circulatory Failure
  Interventions:   Other: Multiple blood sampling;   Other: Simple blood sampling
  Sponsor:   Assistance Publique - Hôpitaux de Paris
  Recruiting
• Less Infections for the Diabetic Foot

  NCT03615807

  Condition:   Diabetic Foot
  Interventions:   Procedure: Surgical debridement (if needed);   Diagnostic Test: Microbiological sampling;   Procedure: Revascularisation (if needed).;   Device: Off-loading;   Behavioral: Patient's education and instructions;   Procedure: Wound debridement;   Drug: Antibiotic duration
  Sponsor:   University Hospital, Geneva
  Recruiting
• Wound Infection Detection Evaluation, WIDE

  NCT03883230

  Conditions:   Wound Infection Bacterial;   Ulcer Foot;   Diabetic Foot;   Diagnostic Self Evaluation
  Intervention:   Diagnostic Test: GLYWD
  Sponsor:   Cumbria Partnership NHS Foundation Trust
  Recruiting
• Ceftriaxone as Home IV for Staph Infections

  NCT04141787

  Conditions:   Staphylococcal Infections;   Osteomyelitis;   CNS Infection;   Septic Arthritis;   Diabetic Foot Infection;   Vertebral Osteomyelitis;   Abscess;   Coagulase Negative Staphylococcal Infection
  Interventions:   Drug: Ceftriaxone;   Drug: Usual Antibiotics (Cloxacillin, Cefazolin, Daptomycin)
  Sponsor:   Vancouver Island Health Authority
  Recruiting
• Diabetic Foot Ulcer and Wound Infection

  NCT03827902

  Conditions:   Diabetes Complications;   Diabetes;   Diabetic Foot Ulcer;   Wound Infection
  Intervention:   Device: Telcare 2.0 BGM
  Sponsors:   University of Texas Southwestern Medical Center;   Parkland Health & Hospital System
  Recruiting
• Identification of Cardiovascular and Molecular Prognostic Factors for the Mid- and Long-term Outcome of Sepsis

  NCT03620409

  Conditions:   Sepsis;   Septic Cardiomyopathy;   Cardiomyopathies
  Intervention:  
  Sponsors:   Jena University Hospital;   Department of Anesthesiology and Intensive Care Medicine, JUH;   Department of Cardiothoracic Surgery, JUH;   Department of Clinical Chemistry and Laboratory Medicine, JUH;   Department of Biochemistry, Center for Molecular Biomedicine (CMB), FSU Jena;   Systems Biology and Bioinformatics, Hans-Knöll Institute Jena;   Institute of Pharmacy, FSU Jena
  Recruiting
• Perioperative Antibiotic Therapy to Prevent Cardiac Implantable Electronic Device Infections.

  NCT02809131

  Conditions:   Sick Sinus Syndrome;   Complete Heart Block;   Syncope;   Chronic Systolic Heart Failure
  Interventions:   Drug: polymixin/bacitracin;   Drug: cephalexin, or levofloxacin, or clindamycin;   Drug: Saline
  Sponsors:   Vanderbilt University Medical Center;   Thomas Jefferson University;   The Cooper Health System;   Valley Health System;   Medtronic
  Recruiting
• Oritavancin for Staphylococcus Aureus Infections in Opioid Users

  NCT03761953

  Conditions:   Staphylococcus Aureus Bacteremia;   Staphylococcus Aureus Endocarditis
  Intervention:   Drug: Oritavancin Injection
  Sponsor:   University of Pennsylvania
  Recruiting
• Tumescent Anesthesia Antibiotic Delivery (TAAD)

  NCT03226626

  Conditions:   Surgical Site Infection;   Thrombosis;   Sepsis
  Interventions:   Drug: Tumescent Anesthesia and antibiotic delivery (TAAD) plus IVAD;   Device: SubQKath
  Sponsors:   HK Surgical, Inc.;   University of California, Riverside
  Not yet recruiting
• Innovative Anti-pneumococcal Vaccine Strategies in Patients With ANCA-associated Vasculitis Receiving Rituximab Therapy

  NCT03069703

  Condition:   Invasive Pneumococcal Infection
  Interventions:   Biological: PCV13;   Biological: PPV23;   Drug: Rituximab
  Sponsors:   Assistance Publique - Hôpitaux de Paris;   EUCLID Clinical Trials Platform;   Recherche Clinique Paris Descartes Necker Cochin Sainte Anne;   CIC Cochin-Pasteur;   Groupe Français d'Etude des Vascularites (GFEV)
  Recruiting
• Myocardial Injury and Severe Pneumococcal Pneumonia

  NCT03058211

  Conditions:   Pneumonia, Pneumococcal;   Myocardial Ischemia
  Interventions:   Diagnostic Test: Echocardiography;   Diagnostic Test: Cardiac Magnetic resonance
  Sponsor:   Alejandro Rodriguez Oviedo , MD
  Recruiting
• Analysis of the Microbiota and STEMI

  NCT03439592

  Conditions:   STEMI;   Diabetes Mellitus;   Microbial Colonization
  Intervention:   Diagnostic Test: collection of fecal material
  Sponsor:   University of Campania "Luigi Vanvitelli"
  Recruiting
• Multi-omics Study on Gut Microbiota in Critical Ill Patients After Cardiopulmonary Bypass

  NCT04032938

  Conditions:   Sepsis;   Cardiopulmonary Bypass
  Intervention:   Procedure: extracorporeal circulation during cardiac surgery
  Sponsor:   Peking Union Medical College Hospital
  Recruiting
• Novel Strategy to Encourage Early Removal of Central Venous Catheters

  NCT04136561

  Conditions:   Vascular Access Complication;   Central Line Complication;   Central Line-Associated Infection;   Superficial Vein Thrombosis;   Deep Vein Thrombosis
  Intervention:   Device: Midline catheter
  Sponsor:   William Beaumont Hospitals
  Not yet recruiting
• People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents

  NCT03520660

  Conditions:   Diabetes Mellitus;   Hepatitis C, Chronic;   Cardiovascular Diseases
  Intervention:  
  Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  Recruiting
• Study to Determine the Hepatitis C Virus Infection Prevalence Among Patients Attended Primarily for Vasculitis

  NCT03693586

  Conditions:   Chronic Hepatitis c;   Vasculitis
  Intervention:  
  Sponsors:   Hospital General de Mexico;   AbbVie
  Recruiting
• Standard Treatment Associated With Phage Therapy Versus Placebo for Diabetic Foot Ulcers Infected by S. Aureus

  NCT02664740

  Conditions:   Diabetic Foot;   Staphylococcal Infections
  Interventions:   Drug: Topical anti-Staphylococcus bacteriophage therapy;   Drug: Topical placebo corresponding to anti-Staphylococcus bacteriophage therapy
  Sponsors:   Centre Hospitalier Universitaire de Nīmes;   Pherecydes Pharma
  Not yet recruiting
• Outcomes of Total Arterial Coronary Artery Bypass Grafting

  NCT03231527

  Conditions:   Coronary Artery Disease;   Surgical Wound Infection
  Intervention:   Procedure: coronary artery bypass grafting (CABG)
  Sponsors:   University of Glasgow;   Campus Bio-Medico University;   Universitaire Ziekenhuizen Leuven;   Thorax Centrum Twente;   Golden Jubilee National Hospital
  Recruiting
• Management of Infection Risk in Non-comparative Trial (MINT)

  NCT03670329

  Condition:   Venous Leg Ulcer
  Intervention:   Device: URGO2875
  Sponsor:   Laboratoires URGO
  Not yet recruiting
• Combination Treatment for Enterococcus Faecalis Bacteriemia Multicenter, Observational Study"

  NCT04070820

  Conditions:   Enterococcal Bacteraemia;   Enterococcus Faecalis Infection;   Enterococcal Endocarditis;   Bloodstream Infection
  Intervention:  
  Sponsor:   University of Bologna
  Not yet recruiting
• DURAFIBER Ag Post-Market Clinical Follow-Up

  NCT03277131

  Conditions:   Wounds and Injuries;   Venous Leg Ulcer;   Infection
  Intervention:   Device: DURAFIBER Ag
  Sponsor:   Smith & Nephew, Inc.
  Recruiting
• Study of Clinical Features and Genetics of Hyperimmunoglobulin E Recurrent Infection

  NCT00006150

  Conditions:   Coronary Aneurysm;   Dermatitis, Atopic;   Immune System Diseases;   STAT3 Transcription Factor;   Job Syndrome
  Intervention:  
  Sponsors:   National Institute of Allergy and Infectious Diseases (NIAID);   Albert Einstein College of Medicine
  Recruiting
• Study on the Effect of Influenza Vaccination After Heart Attack on Future Cardiovascular Prognosis

  NCT02831608

  Conditions:   Myocardial Infarction;   Influenza, Human;   Influenza Vaccines;   Heart Failure;   Stroke
  Interventions:   Biological: Influenza vaccine;   Biological: Placebo
  Sponsors:   Ole Frobert, MD, PhD;   Swedish Heart Lung Foundation;   Sanofi Pasteur, a Sanofi Company;   Uppsala University;   Lytics
  Recruiting
• Video Assisted Pericardioscopic Surgery: Minimal-invasive Implantation of Epimyocardial Pacemaker Leads in Humans

  NCT03387488

  Conditions:   Dysrhythmia, Cardiac;   Heart Failure;   Pacemaker Electrode Infection;   Hemodialysis-Induced Symptom;   Bradycardia
  Intervention:   Device: StingrayTM, Medtronic®
  Sponsor:   RWTH Aachen University
  Not yet recruiting
• Anti-chlamydophila Antibiotic Combination Therapy in the Treatment of Patients With Coronary Heart Disease

  NCT03618108

  Conditions:   Coronary Heart Disease;   Chlamydophila Pneumoniae Infections
  Interventions:   Drug: Doxycycline Capsule;   Drug: Azithromycin Capsule;   Drug: Rifabutin Oral Capsule;   Drug: Placebo oral capsule;   Drug: Placebo Oral Tablet
  Sponsors:   Cadrock Pty. Ltd.;   Centre for Digestive Diseases, Australia
  Recruiting
• Search for Biomarkers of Infection and Inflammation in Patients With Acute Stroke.

  NCT03812666

  Conditions:   Stroke, Acute;   Pneumonia, Bacterial
  Intervention:  
  Sponsors:   Jakob Ström;   Örebro University
  Recruiting
• Direct Lysis of Staph Aureus Resistant Pathogen Trial of Exebacase

  NCT04160468

  Conditions:   Staphylococcus Aureus Bacteremia;   Staphylococcus Aureus Endocarditis
  Interventions:   Drug: Exebacase;   Drug: Placebo
  Sponsor:   ContraFect
  Not yet recruiting
• At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

  NCT01931644

  Conditions:   All Diagnosed Health Conditions;   ADD/ADHD;   Alopecia Areata;   Ankylosing Spondylitis;   Asthma;   Atopic Dermatitis Eczema;   Beta Thalassemia;   Bipolar Disorder;   Breast Cancer;   Celiac Disease;   Cervical Cancer;   Chronic Inflammatory Demyelinating Polyneuropathy;   Chronic Kidney Diseases;   Chronic Obstructive Pulmonary Disease;   Colon Cancer;   Colorectal Cancer;   Crohn's Disease;   Cystic Fibrosis;   Depression;   Diabetes Mellitus;   Duchenne Muscular Dystrophy;   Endometriosis;   Epilepsy;   Facioscapulohumeral Muscular Dystrophy;   G6PD Deficiency;   General Anxiety Disorder;   Hepatitis B;   Hereditary Hemorrhagic Telangiectasia;   HIV/AIDS;   Human Papilloma Virus;   Huntington's Disease;   Idiopathic Thrombocytopenic Purpura;   Insomnia;   Kidney Cancer;   Leukemia;   Lung Cancer;   Lupus Nephritis;   Lymphoma;   Melanoma;   Multiple Myeloma;   Multiple Sclerosis;   Myositis;   Myotonic Dystrophy;   Ovarian Cancer;   Pancreatic Cancer;   Parkinson's Disease;   Polycystic Kidney Diseases;   Prostate Cancer;   Psoriasis;   Psoriatic Arthritis;   Rosacea;   Scleroderma;   Sickle Cell Anemia;   Sickle Cell Trait;   Sjogren's Syndrome;   Skin Cancer;   Spinal Muscular Atrophy;   Systemic Lupus Erythematosus;   Thrombotic Thrombocytopenic Purpura;   Trisomy 21;   Ulcerative Colitis
  Intervention:  
  Sponsor:   Sanguine Biosciences
  Recruiting
• Midlines and Thrombophlebitis

  NCT03725293

  Conditions:   Catheter Infection;   Catheter Thrombosis;   Catheter Complications
  Interventions:   Device: Angiodynamics BioFlo Midline Catheter;   Device: Teleflex Arrowg+ard Blue Advanced Midline Catheter
  Sponsors:   William Beaumont Hospitals;   Teleflex
  Recruiting
• Short or Long Antibiotic Regimes in Orthopaedics

  NCT03806166

  Conditions:   Osteomyelitis;   Prosthetic Joint Infection;   Diabetic Foot
  Interventions:   Other: Shorter Systemic Antibiotics;   Other: Standard treatment
  Sponsor:   Oxford University Hospitals NHS Trust
  Recruiting
• Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

  NCT01431326

  Conditions:   Adenovirus;   Anesthesia;   Anxiety;   Anxiolysis;   Autism;   Autistic Disorder;   Bacterial Meningitis;   Bacterial Septicemia;   Benzodiazepine;   Bipolar Disorder;   Bone and Joint Infections;   Central Nervous System Infections;   Convulsions;   Cytomegalovirus Retinitis;   Early-onset Schizophrenia Spectrum Disorders;   Epilepsy;   General Anesthesia;   Gynecologic Infections;   Herpes Simplex Virus;   Infantile Hemangioma;   Infection;   Inflammation;   Inflammatory Conditions;   Intra-abdominal Infections;   Lower Respiratory Tract Infections;   Migraines;   Pain;   Pneumonia;   Schizophrenia;   Sedation;   Seizures;   Skeletal Muscle Spasms;   Skin and Skin-structure Infections;   Treatment-resistant Schizophrenia;   Urinary Tract Infections;   Withdrawal;   Sepsis;   Gram-negative Infection;   Bradycardia;   Cardiac Arrest;   Cardiac Arrhythmia;   Staphylococcal Infections;   Nosocomial Pneumonia;   Neuromuscular Blockade;   Methicillin Resistant Staphylococcus Aureus;   Endocarditis;   Neutropenia;   Headache;   Fibrinolytic Bleeding;   Pulmonary Arterial Hypertension;   CMV Retinitis;   Hypertension;   Chronic Kidney Diseases;   Hyperaldosteronism;   Hypokalemia;   Heart Failure;   Hemophilia;   Heavy Menstrual Bleeding;   Insomnia
  Intervention:   Drug: The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
  Sponsors:   Daniel Benjamin;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   The Emmes Company, LLC
  Recruiting
• Stress Ulcer Prophylaxis Versus Placebo in Critically Ill Infants With Congenital Heart Disease

  NCT03667703

  Conditions:   Congenital Heart Disease;   Upper Gastrointestinal Bleeding;   Stress Ulcer;   Infection
  Interventions:   Drug: Ranitidine;   Drug: Placebo
  Sponsors:   Boston Children’s Hospital;   The Gerber Foundation
  Recruiting