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• Optimisation of Decision Making for Defibrillator Implantation in Hypertrophic Cardiomyopathy

  NCT03846297

  Condition:   Hypertrophic Cardiomyopathy
  Intervention:  
  Sponsor:   Assistance Publique - Hôpitaux de Paris
  Not yet recruiting
• French Hypertrophic Cardiomyopathy Observatory

  NCT01091480

  Condition:   Hypertrophic Cardiomyopathy
  Intervention:  
  Sponsor:   French Cardiology Society
  Recruiting
• Will Elevated Left Ventricle Filling Pressures Decrease by a Group Exercise Program in Patients With Hypertrophic CardioMyopathy?

  NCT03537183

  Condition:   Hypertrophic Cardiomyopathy
  Intervention:   Other: Exercise training
  Sponsors:   Bispebjerg Hospital;   Rigshospitalet, Denmark
  Recruiting
• A Prospective Incident Study of Arrhythmias in Hypertrophic Cardiomyopathy

  NCT04112290

  Condition:   Hypertrophic Cardiomyopathy
  Intervention:  
  Sponsor:   Mayo Clinic
  Recruiting
• 3D Non-invasive Myocardial Electrical Propagation Mapping as a New Tool to Predict Sudden Death Risk in Patients With Hypertrophic Cardiomyopathy

  NCT03550573

  Condition:   Hypertrophic Cardiomyopathy
  Intervention:   Device: CardioInsight™ Noninvasive 3D Mapping System
  Sponsor:   Hospices Civils de Lyon
  Not yet recruiting
• Study of Myocardial Deformation Parameters in Patients With Hypertrophic Cardiomyopathy

  NCT04112511

  Condition:   Hypertrophic Cardiomyopathy
  Intervention:  
  Sponsor:   AHEPA University Hospital
  Recruiting
• Effect of Metoprolol in Post Alcohol Septal Ablation Patients With Hypertrophic Cardiomyopathy

  NCT04133532

  Condition:   Hypertrophic Cardiomyopathy
  Intervention:   Drug: Metoprolol
  Sponsor:   University Hospital, Motol
  Not yet recruiting
• Outcome of Different Pathogenic Mutations in Hypertrophic Cardiomyopathy

  NCT03726424

  Condition:   Hypertrophic Cardiomyopathy
  Intervention:  
  Sponsor:   Tongji Hospital
  Recruiting
• Sleep Apnea and Hypertrophic Cardiomyopathy (HCM)

  NCT03327623

  Condition:   Hypertrophic Cardiomyopathy
  Intervention:  
  Sponsors:   Mayo Clinic;   National Heart, Lung, and Blood Institute (NHLBI)
  Recruiting
• Sacubitril/Valsartan vs Lifestyle in Hypertrophic Cardiomyopathy

  NCT03832660

  Condition:   Hypertrophic Cardiomyopathy
  Interventions:   Behavioral: Lifestyle;   Drug: Sacubitril/Valsartan
  Sponsors:   Newcastle University;   Azienda Ospedaliero-Universitaria Careggi;   University Hospital Regensburg;   Institute for Cardiovascular Diseases of Vojvodina;   University of Belgrade
  Recruiting
• Prospective Evaluation Of Exercise-Induced Cardiac Conduction Instability In Predicting Ventricular Fibrillation Events In Hypertrophic Cardiomyopathy

  NCT04157205

  Condition:   Hypertrophic Cardiomyopathy
  Intervention:   Diagnostic Test: Non-invasive ECG imaging - CardioInsight test
  Sponsors:   Imperial College London;   Imperial College Healthcare NHS Trust;   Medtronic;   Barts & The London NHS Trust;   University of Oxford;   Daniel Bagshaw Trust
  Recruiting
• High Intensity Exercise for Increasing Fitness in Patients With Hypertrophic Cardiomyopathy

  NCT03335332

  Condition:   Hypertrophic Cardiomyopathy
  Interventions:   Behavioral: High intensity exercise;   Behavioral: Moderate intensity exercise
  Sponsors:   University of Texas Southwestern Medical Center;   Biotronik SE & Co. KG
  Recruiting
• Predictive Factors and Consequences of Myocardial Fibrosis in Hypertrophic Cardiomyopathy

  NCT02922517

  Condition:   Hypertrophic Cardiomyopathy
  Intervention:  
  Sponsors:   Nantes University Hospital;   University Hospital, Lille;   Rennes University Hospital;   Institut National de la Santé Et de la Recherche Médicale, France
  Recruiting
• Evaluating Microvascular Dysfunction in Symptomatic Patients With HypertroPhic CaRdiomyopathy

  NCT02994615

  Condition:   Hypertrophic Cardiomyopathy
  Intervention:  
  Sponsor:   Lawson Health Research Institute
  Recruiting
• Differentiating Hypertrophic Cardiomyopathy From Hypertensive Heart Disease

  NCT03271385

  Conditions:   Hypertrophic Cardiomyopathy;   Hypertensive Heart Disease
  Intervention:   Diagnostic Test: evaluated by the predetermined differentiating formula
  Sponsors:   RenJi Hospital;   Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University;   Ruijin Hospital;   LanZhou University;   Kunming Medical University;   Beijing Anzhen Hospital;   West China Hospital
  Recruiting
• Assessment of the Relations Between Endothelial and Venous Dysfunctions and Left Ventricular Obstruction in Genetic Hypertrophic Cardiomyopathies

  NCT04129905

  Conditions:   Hypertrophic Cardiomyopathy;   Endothelial Dysfunction
  Interventions:   Biological: BNP blood sample test;   Diagnostic Test: Electrocardiogram;   Diagnostic Test: Holter ECG;   Diagnostic Test: Echocardiography;   Diagnostic Test: Air venous plethysmography;   Diagnostic Test: Upper member arterial Doppler echography with analysis of FMD;   Biological: Endothelial function biomarkers
  Sponsors:   University Hospital, Bordeaux;   Fédération Française de Cardiologie;   Fondation Bordeaux Université;   Amicus Therapeutics
  Not yet recruiting
• Evaluating the Effect of Spironolactone on Hypertrophic Cardiomyopathy

  NCT02948998

  Conditions:   Hypertrophic Cardiomyopathy;   Fibrosis
  Intervention:   Drug: Spironolactone
  Sponsors:   Xinhua Hospital, Shanghai Jiao Tong University School of Medicine;   Ruijin Hospital;   RenJi Hospital;   Shanghai Jiao Tong University Affiliated Sixth People’s Hospital
  Not yet recruiting
• Non-Invasive Radiation Ablation in Patients With Hypertrophic CardioMyopathy: NIRA-HOCM

  NCT04153162

  Condition:   Hypertrophic Cardiomyopathy
  Intervention:   Device: Stereotactic body radiation therapy
  Sponsors:   Barts & The London NHS Trust;   Barts Cardiovascular CTU (Queen Mary University of London);   Barts Charity
  Not yet recruiting
• CArdiac Desynchronization In Obstructive HCM, CARDIO-HCM

  NCT01332162

  Condition:   Hypertrophic Obstructive Cardiomyopathy (HOCM)
  Interventions:   Device: Biventricular pacing;   Device: No Pacing
  Sponsor:   Hospital Clinic of Barcelona
  Recruiting
• Functional Capacity and Quality of Life Following Septal Myectomy in Patients With HCM

  NCT03092843

  Condition:   Hypertrophic Cardiomyopathy
  Intervention:  
  Sponsor:   The Cleveland Clinic
  Recruiting
• Efficacy of Psychotherapy for Improving Quality of Life in Patients With Hypertrophic Cardiomyopathy and Depression

  NCT03706001

  Conditions:   Hypertrophic Cardiomyopathy;   Depression;   Anxiety;   Psychotherapy
  Intervention:   Other: Psychotherapy
  Sponsor:   Xijing Hospital
  Not yet recruiting
• Mitral Valve in Hypertrophic Cardiomyopathy

  NCT03877731

  Condition:   Hypertrophic Obstructive Cardiomyopathy
  Interventions:   Procedure: isolated septal myectomy;   Procedure: septal myectomy + edge-to-edge mitral valve repair;   Procedure: septal myectomy + posterior leaflet sliding plasty;   Procedure: septal myectomy + secondary chordae transection
  Sponsor:   Tomsk National Research Medical Center of the Russian Academy of Sciences
  Recruiting
• HCM-AF Ablation With ACUTUS

  NCT04090437

  Conditions:   Atrial Fibrillation;   Hypertrophic Cardiomyopathy
  Intervention:   Procedure: Catheter ablation procedure
  Sponsors:   Royal Brompton & Harefield NHS Foundation Trust;   Acutus Medical
  Not yet recruiting
• The Chinese Hypertrophic Cardiomyopathy Study(CHCS)

  NCT02696135

  Condition:   Cardiomyopathy, Hypertrophic
  Intervention:  
  Sponsor:   China National Center for Cardiovascular Diseases
  Recruiting
• Study of Efficacy of Oral Sacubitril/Valsartan Adult Patients With Non-obstructive Hypertrophic Cardiomyopathy

  NCT04164732

  Condition:   Cardiomyopathy, Hypertrophic
  Interventions:   Drug: LCZ696;   Drug: Placebo
  Sponsor:   Novartis Pharmaceuticals
  Not yet recruiting
• The Effect of Metoprolol in Patients With Hypertrophic Obstructive Cardiomyopathy.

  NCT03532802

  Condition:   Hypertrophic Cardiomyopathy
  Interventions:   Drug: Metoprolol Succinate;   Drug: Placebo oral capsule
  Sponsor:   Steen Hvitfeldt Poulsen
  Recruiting
• OPIE in the Thin Interventricular Septum

  NCT04050579

  Condition:   Hypertrophic Cardiomyopathy
  Intervention:   Device: on-pump intracardiac echocardiography
  Sponsor:   NYU Langone Health
  Not yet recruiting
• Genomic Sequencing in Patients With HCM Undergoing Septal Myectomy

  NCT03043209

  Conditions:   Hypertrophic Cardiomyopathy;   Genetic Disease;   Gene Product Sequence Variation
  Intervention:   Genetic: Genomic sequencing
  Sponsor:   The Cleveland Clinic
  Recruiting
• Effects of Ranolazine on Coronary Microvascular Dysfunction in Patients With Hypertrophic Cardiomyopathy

  NCT03953989

  Condition:   HCM - Hypertrophic Non-Obstructive Cardiomyopathy
  Intervention:   Drug: Ranolazine PR (prolonged-release) 500 mg 1 tablet bis in die and 750 mg 1 tablet bis in die
  Sponsors:   IRCCS San Raffaele;   Menarini International Operations Luxembourg SA
  Recruiting
• Pacemaker Therapy for Drug-refractory Symptoms in Mid-cavity Hypertrophic Cardiomyopathy

  NCT03450252

  Condition:   Cardiomyopathy, Hypertrophic
  Interventions:   Device: Active pacing;   Device: Back-up pacing
  Sponsor:   Barts & The London NHS Trust
  Recruiting
• "Cardiac Rehabilitation in Patients With Hypertrophic Cardiomyopathy".

  NCT03178357

  Condition:   Cardiac Rehabilitation
  Interventions:   Other: Cardiac rehabilitation + standard therapy;   Other: Standard therapy
  Sponsor:   Institute of Cardiology, Warsaw, Poland
  Recruiting
• Extended ECG Monitoring in HCM Patients

  NCT04056715

  Conditions:   Hypertrophic Cardiomyopathy;   Nonsustained Ventricular Tachycardia;   Ventricular Tachycardia;   Atrial Fibrillation;   Arrhythmia
  Intervention:   Device: Zio XT
  Sponsor:   iRhythm Technologies, Inc.
  Not yet recruiting
• Biomarkers in Aortic Stenosis - B.A.S.S.

  NCT01334801

  Conditions:   Aortic Stenosis;   Disorder of Prosthetic Cardiac Valve;   Aortic Valve Insufficiency;   Mitral Valve Insufficiency;   Hypertrophic Cardiomyopathy;   Tricuspid Valve Insufficiency
  Intervention:   Procedure: Blood Draw
  Sponsor:   Mayo Clinic
  Recruiting
• Microvascular Dysfunction in Nonischemic Cardiomyopathy: Insights From CMR Assessment of Coronary Flow Reserve

  NCT03249272

  Conditions:   Hypertrophic Cardiomyopathy;   Non-ischemic Dilated Cardiomyopathy;   Microvascular Ischaemia of Myocardium
  Interventions:   Drug: Regadenoson;   Drug: Adenosine
  Sponsor:   Duke University
  Recruiting
• The Effect of TASH in Patients With HOCM

  NCT04066777

  Condition:   Hypertrophic Obstructive Cardiomyopathy
  Intervention:   Procedure: alcohol septal ablation
  Sponsor:   Steen Hvitfeldt Poulsen
  Recruiting
• Manganese-Enhanced Magnetic Resonance Imaging of the Myocardium

  NCT03607669

  Conditions:   Ischemic Cardiomyopathy;   Dilated Cardiomyopathy;   Hypertrophic Cardiomyopathy
  Intervention:   Other: Mangafodipir trisodium
  Sponsor:   University of Edinburgh
  Recruiting
• Molecular and Imaging Studies of Cardiovascular Health and Disease

  NCT02804269

  Conditions:   Healthy;   Dilated Cardiomyopathy;   Hypertrophic Cardiomyopathy;   Ischemic Heart Disease
  Interventions:   Other: Cardiovascular Magnetic Resonance;   Other: Fatmass measurement
  Sponsor:   National Heart Centre Singapore
  Recruiting
• Evaluation of HEArt invoLvement in Patients With FABRY Disease

  NCT03362164

  Conditions:   Rare Diseases;   Fabry Disease;   Fabry Disease, Cardiac Variant;   Hypertrophic Cardiomyopathy
  Intervention:  
  Sponsors:   Wuerzburg University Hospital;   Competence Network Heart Failure;   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA);   St George's, University of London
  Recruiting
• Metabolomic Study of All-age Cardiomyopathy

  NCT03061994

  Conditions:   Dilated Cardiomyopathy;   Hypertrophic Cardiomyopathy;   Arrhythmogenic Right Ventricular Cardiomyopathy;   Left Ventricular Non-compaction;   Restrictive Cardiomyopathy
  Intervention:  
  Sponsor:   Beijing Institute of Heart, Lung and Blood Vessel Diseases
  Recruiting
• An Integrative-"Omics" Study of Cardiomyopathy Patients for Diagnosis and Prognosis in China

  NCT03076580

  Conditions:   Dilated Cardiomyopathy;   Hypertrophic Cardiomyopathy;   Arrhythmogenic Right Ventricular Cardiomyopathy;   Left Ventricular Non-compaction;   Restrictive Cardiomyopathy
  Intervention:  
  Sponsors:   Beijing Institute of Heart, Lung and Blood Vessel Diseases;   Chinese Academy of Medical Sciences, Fuwai Hospital;   Beijing Anzhen Hospital
  Recruiting
• Gene Therapy for Male Patients With Danon Disease Using RP-A501; AAV9.LAMP2B

  NCT03882437

  Condition:   Danon Disease
  Intervention:   Biological: RP-A501
  Sponsor:   Rocket Pharmaceuticals Inc.
  Recruiting
• Pediatric Cardiomyopathy Mutation Analysis

  NCT02432092

  Conditions:   Cardiomyopathies;   Dilated Cardiomyopathy;   Hypertrophic Cardiomyopathy;   Restrictive Cardiomyopathy;   Arrhythmogenic Right Ventricular Cardiomyopathy;   Left Ventricular Non-compaction Cardiomyopathy
  Intervention:  
  Sponsors:   Indiana University;   American Heart Association
  Recruiting
• Risk Stratification in Children and Adolescents With Primary Cardiomyopathy

  NCT03572569

  Conditions:   Primary Cardiomyopathy;   Dilated Cardiomyopathy;   Hypertrophic Cardiomyopathy;   Left Ventricular Noncompaction;   Restrictive Cardiomyopathy;   Arrhythmogenic Right Ventricular Cardiomyopathy
  Intervention:  
  Sponsors:   German Heart Institute;   Deutsches Zentrum für Herz-Kreislauf-Forschung (DZHK)
  Recruiting
• Stress Echo 2020 - The International Stress Echo Study

  NCT03049995

  Conditions:   Coronary Artery Disease;   Heart Failure;   Hypertrophic Cardiomyopathy;   Aortic Valve Disease;   Athletes Heart;   Tetralogy of Fallot;   Pulmonary Arterial Hypertension
  Interventions:   Procedure: Left ventricular contractile reserve SE;   Procedure: B-lines SE;   Procedure: Left ventricular outflow tract gradient SE;   Procedure: Diastolic function SE;   Procedure: Mitral regurgitation SE;   Procedure: Pulmonary hemodynamics SE;   Procedure: Coronary flow reserve SE
  Sponsors:   Fatebenefratelli Hospital;   Institute of Clinical Physiology, CNR, Pisa,Italy;   Salerno Hospital, Italy;   Monaldi Hospital, Napoli, Italy;   University of Pisa, Italy;   San Luca Hospital, Lucca, Italy;   Careggi University Hospital, Florence, Italy;   Federico II University;   San Carlo Public Hospital, Potenza, Italy;   Royal Brompton & Harefield NHS Foundation Trust;   Ospedale dell'Angelo;   University of Parma;   Hospital Clinics, Trieste, Italy;   Federal University of Rio Grande do Sul;   Hospital San José, Criciuma, Brasil;   Hospital San Vicente de Paulo, Passo Fundo, Brasil;   University of Belgrade,Serbia;   University of Szeged, Hungary;   Elisabeth Hospital, Hodmezovasarhely, Hungary;   Sandro Pertini Hospital, Rome, Italy;   Hospital Clinics, Bari, Italy;   Ospedale Nottola, Siena, Italy;   University of Catania, Italy;   Medika Cardiocenter, Saint Petersburg, Russian Federation;   Acibadem City Clinic Tokuda Hospital;   Investigaciones Medicas, Buenos Aires, Argentina;   Tomsk National Research Scientific Centre of Russian Academy of Sciences, Tomsk, Russian Federation
  Recruiting
• Prognosis of Subjects With Unexplainable Precordial Deep T-wave Inversion Without Wall Thickness> 15mm

  NCT02692508

  Conditions:   Cardiomyopathy;   Hypertrophic
  Intervention:  
  Sponsors:   Chinese Academy of Medical Sciences, Fuwai Hospital;   Beijing Chao Yang Hospital;   Beijing Anzhen Hospital;   Peking Union Medical College Hospital;   Xuanwu Hospital, Beijing
  Recruiting
• Mobilization of Endothelial Progenitor Cells and Aspirin

  NCT02674958

  Condition:   Hypertrophic Obstructive Cardiomyopathy
  Intervention:   Drug: Aspirin
  Sponsor:   Ottawa Heart Institute Research Corporation
  Recruiting
• China Structural Ventricular Arrhythmias Registry

  NCT03821051

  Condition:   Ventricular Arrythmia
  Intervention:  
  Sponsors:   China National Center for Cardiovascular Diseases;   Renmin Hospital of Wuhan University;   The First Affiliated Hospital with Nanjing Medical University;   Second Affiliated Hospital of Nanchang University;   Sir Run Run Shaw Hospital;   West China Hospital;   Beijing Anzhen Hospital;   General Hospital of Shenyang Military Region;   Xuzhou Central Hospital;   First Affiliated Hospital, Sun Yat-Sen University
  Recruiting
• The PARTNER 3 - AVIV Trial

  NCT03003299

  Conditions:   Aortic Stenosis;   Cardiomyopathy, Hypertrophic
  Intervention:   Device: Edwards SAPIEN 3 transcatheter valve, Model 9600TFX
  Sponsor:   Edwards Lifesciences
  Recruiting
• Prevalence and Characteristics of Transthyretin Amyloidosis in Patients With Left Ventricular Hypertrophy of Unknown Etiology

  NCT03842163

  Condition:   Transthyretin Amyloidosis Cardiomyopathy (ATTR-CM)
  Intervention:   Diagnostic Test: Diagnosis of TTR amyloidosis cardiomyopathy
  Sponsor:   Pfizer
  Recruiting
• Coronary Artery Disease and Coronary Microvascular Disease in Cardiomyopathies Registry

  NCT03479580

  Conditions:   Hypertrophic;   Ischemic;   Restrictive Cardiomyopathy;   Dilated Cardiomyopathies
  Intervention:   Other: Patients with a cardiomyopathy
  Sponsors:   University Hospital, Grenoble;   Clinique Belledonne;   Groupe Hospitalier Mutualiste de Grenoble;   Centre Hospitalier Annecy Genevois;   Centre Hospitalier Metropole Savoie
  Recruiting