Find Clinical Trials

All CategoriesMedications / Interventions»Cc»Cocaine



Join Paid Clinical Trials



  • Conditions:   Cocaine Dependence;   Substance Use Disorders
    Intervention:   Diagnostic Test: magnetic resonance imaging
    Sponsor:   Medical University of South Carolina
    Recruiting

  • Condition:   Cocaine Use Disorder
    Interventions:   Drug: Cocaine;   Drug: Placebo;   Drug: Phentermine;   Drug: Topiramate
    Sponsors:   University of Kentucky;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Condition:   Cocaine Use Disorder
    Intervention:   Behavioral: Contingency Management
    Sponsors:   William Stoops;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Conditions:   Substance Abuse;   Cocaine Dependence
    Interventions:   Drug: Bupropion XL;   Drug: placebo
    Sponsor:   Johns Hopkins University
    Recruiting

  • Condition:   Cocaine Use Disorder
    Interventions:   Radiation: [C-11];   Drug: NOP-1A
    Sponsors:   University of Pittsburgh;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Condition:   Cocaine Dependence
    Intervention:   Other: TMS
    Sponsor:   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Condition:   Cocaine Use Disorder
    Intervention:   Behavioral: CBT-RP
    Sponsors:   New York State Psychiatric Institute;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Condition:   Cocaine Use Disorder
    Interventions:   Drug: Cocaine;   Drug: Placebo oral capsule;   Drug: Methylphenidate
    Sponsors:   Craig Rush;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Condition:   Cocaine Use Disorder
    Interventions:   Drug: Oxytocin;   Drug: Placebo
    Sponsor:   Medical University of South Carolina
    Recruiting

  • Conditions:   Cocaine-Related Disorders;   Anhedonia
    Interventions:   Drug: d-amphetamine;   Behavioral: Contingency management;   Drug: Placebo (for d-amphetamine)
    Sponsors:   University of Illinois at Chicago;   The University of Texas Health Science Center, Houston
    Recruiting

  • Condition:   Cocaine Dependence
    Interventions:   Biological: dAd5GNE Vaccine;   Biological: Placebo
    Sponsor:   Weill Medical College of Cornell University
    Recruiting

  • Conditions:   Mild Cognitive Impairment, So Stated;   Cocaine Use Disorder
    Interventions:   Behavioral: Occupational therapy-based cognitive rehabilitation;   Behavioral: Psychoeducation/games
    Sponsors:   University of California, San Francisco;   San Francisco Veterans Affairs Medical Center
    Recruiting

  • Condition:   Cocaine Dependence
    Interventions:   Behavioral: Computer-assisted behavior therapy;   Drug: Mixed amphetamine salts;   Drug: Computer-assisted CBT plus placebo
    Sponsors:   New York State Psychiatric Institute;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Conditions:   Cocaine Use Disorder;   Cocaine Dependence
    Intervention:   Device: Soterix Medical mini-CT tDCS stimulator
    Sponsors:   Soterix Medical;   Icahn School of Medicine at Mount Sinai
    Recruiting

  • Condition:   Cocaine-Related Disorders
    Interventions:   Behavioral: Acceptance and Commitment Therapy (ACT);   Behavioral: Drug Counseling (DC);   Behavioral: Contingency Management (CM);   Drug: Placebo;   Drug: Modafinil
    Sponsor:   The University of Texas Health Science Center, Houston
    Recruiting

  • Condition:   Cocaine Dependence
    Interventions:   Drug: d-amphetamine;   Radiation: [C-11]FLB 457
    Sponsors:   University of Pittsburgh;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Condition:   Cocaine Use Disorder
    Interventions:   Drug: CI-581a;   Drug: CI-581b;   Behavioral: Motivational Enhancement Therapy (MET);   Behavioral: Mindfulness Based Relapse Prevention
    Sponsors:   New York State Psychiatric Institute;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Condition:   Cocaine Dependence
    Interventions:   Drug: Lorcaserin;   Drug: Placebo Oral Tablet
    Sponsor:   Mclean Hospital
    Recruiting

  • Conditions:   Substance Abuse Problem;   Pregnancy
    Interventions:   Drug: Syntocinon treatment;   Other: Placebo
    Sponsors:   University of North Carolina, Chapel Hill;   Foundation of Hope, North Carolina
    Recruiting

  • Condition:   Cocaine Use Disorder
    Interventions:   Drug: Cariprazine Oral Capsule [Vraylar];   Drug: Placebo oral capsule
    Sponsors:   Anna Rose Childress;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Condition:   Cocaine Use Disorder
    Interventions:   Drug: NS2359;   Drug: placebo
    Sponsors:   University of Pennsylvania;   Saniona;   The Dana Foundation
    Recruiting

  • Conditions:   Cocaine-Related Disorders;   Opioid-Related Disorders
    Interventions:   Drug: Group A Lorcaserin (10mg);   Drug: Group A2 Lorcaserin (20 mg);   Other: Group B Parallel Placebo;   Other: Group B2 Parallel Placebo
    Sponsors:   Virginia Commonwealth University;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Condition:   Cocaine Dependence
    Interventions:   Drug: Mirtazapine 15 MG (administered at Scan 1) and Placebo oral capsule (administered at Scan 2);   Drug: Placebo oral capsule (administered at Scan 1) and Mirtazapine 15 MG (administered at Scan 2)
    Sponsors:   Virginia Commonwealth University;   The University of Texas Medical Branch, Galveston;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Conditions:   Cocaine Dependence;   Alcohol Dependence
    Interventions:   Device: Real cTBS;   Device: Sham cTBS
    Sponsors:   Medical University of South Carolina;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Condition:   Cocaine Use & Co-occuring Opioid Use Disorders
    Interventions:   Drug: Intranasal oxytocin;   Drug: Intranasal placebo
    Sponsor:   VA Office of Research and Development
    Recruiting

  • Condition:   Cocaine Use Disorder
    Interventions:   Behavioral: Treatment As Usual (TAU);   Behavioral: TAU plus Rapid Abstinence Initiation (RAI);   Behavioral: TAU plus RAI plus Cognitive Control Training (CCT)
    Sponsor:   Yale University
    Recruiting

  • Condition:   Cocaine-Related Disorders
    Interventions:   Drug: Psilocybin;   Drug: Diphenhydramine
    Sponsor:   University of Alabama at Birmingham
    Recruiting

  • Condition:   Cocaine-Related Disorders
    Interventions:   Drug: d-amphetamine;   Radiation: [C-11]NPA
    Sponsors:   Gale Richardson;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Conditions:   Cocaine Dependence;   Healthy
    Interventions:   Drug: N-acetyl cysteine;   Diagnostic Test: [18F]FDG PET scan;   Diagnostic Test: 1H MRS;   Diagnostic Test: [11C]APP311 PET scan
    Sponsor:   Yale University
    Recruiting

  • Conditions:   D3 Dopamine Receptor;   Cocaine-dependent;   Healthy Volunteer
    Intervention:   Drug: [18F]FTP PET/CT
    Sponsor:   University of Pennsylvania
    Recruiting

  • Condition:   Alcohol Use Disorder
    Interventions:   Behavioral: Normative Feedback;   Behavioral: Inhibitory Control Training;   Behavioral: Working Memory Training
    Sponsors:   Craig Rush;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Conditions:   Cocaine Use Disorder;   Contingency Management
    Interventions:   Behavioral: prize contingency management on a traditional twice weekly schedule for cocaine abstinence;   Behavioral: prize contingency management on a variable interval schedule for cocaine abstinence;   Behavioral: standard care
    Sponsors:   UConn Health;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Condition:   Cocaine Dependence
    Interventions:   Drug: Methylphenidate;   Drug: Alpha Methyl Para Tyrosine (AMPT);   Other: [11C]PHNO;   Other: [11C]raclopride
    Sponsor:   Yale University
    Recruiting

  • Conditions:   Cocaine Use Disorders;   HIV
    Interventions:   Device: Active Cognitive Training (ACT);   Device: Control Training (CON)
    Sponsor:   Duke University
    Recruiting

  • Conditions:   Smoking;   Cannabis
    Intervention:   Drug: cannabis
    Sponsor:   Yale University
    Recruiting

  • Condition:   Postdural Puncture Headache
    Interventions:   Procedure: Sphenopalatine Ganglion Block;   Procedure: Placebo
    Sponsor:   University of Arkansas
    Not yet recruiting

  • Conditions:   Cocaine Abuse;   Cocaine Dependence;   Opiate Dependence;   Alcohol Dependence;   Substance Abuse
    Interventions:   Drug: modafinil;   Drug: d-amphetamine;   Drug: L-Dopa;   Drug: Naltrexone
    Sponsors:   The University of Texas Health Science Center, Houston;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Conditions:   Opioid-use Disorder;   Cocaine Use Disorder;   Marijuana Use Disorder;   Healthy Controls
    Intervention:  
    Sponsors:   Virginia Commonwealth University;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Condition:   Cocaine Use Disorder
    Interventions:   Behavioral: Prize-Based Contingency Management;   Behavioral: Treatment As Usual Outpatient Substance Use Treatment
    Sponsor:   VA Office of Research and Development
    Not yet recruiting

  • Conditions:   Healthy Volunteers;   Rhinovirus
    Intervention:   Biological: RG-HRV16
    Sponsors:   University of North Carolina, Chapel Hill;   Environmental Protection Agency (EPA)
    Not yet recruiting

  • Conditions:   Alcohol Use;   Alcohol Drinking;   Drinking Behavior
    Interventions:   Other: Smartphone breathalyzer device/app use;   Other: BAC estimator app use;   Other: Text messaging procedure
    Sponsors:   University of Florida;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting

  • Conditions:   Cleft Palate;   Tube Disorders Eustachian;   Velopharyngeal Incompetence Due to Cleft Palate;   Velopharyngeal Insufficiency
    Interventions:   Device: EarPopper;   Device: EMST150
    Sponsors:   Noel Jabbour;   National Institute on Deafness and Other Communication Disorders (NIDCD)
    Not yet recruiting

  • Conditions:   Sleep-disordered Breathing;   Major Depressive Disorder
    Intervention:   Device: Positive Airway Pressure (PAP)
    Sponsor:   University of Michigan
    Recruiting

  • Condition:   Multiple Sclerosis
    Intervention:   Other: PAP therapy
    Sponsors:   University of Michigan;   National Multiple Sclerosis Society
    Recruiting

  • Condition:   Coronary Artery Disease
    Interventions:   Device: Rotational atherectomy;   Device: Cutting Balloon Angioplasty
    Sponsor:   Icahn School of Medicine at Mount Sinai
    Recruiting

  • Condition:   Constipation
    Interventions:   Diagnostic Test: Rectal Barostat Study;   Diagnostic Test: Fecoflowmetry
    Sponsors:   Mayo Clinic;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    Recruiting

  • Conditions:   Chronic Pain;   Opiate Dependence;   Lower Back Pain
    Interventions:   Device: iTBS to the left dlPFC;   Device: Sham iTBS to the left dlPFC;   Device: cTBS to the mPFC;   Device: Sham cTBS to the mPFC
    Sponsor:   Medical University of South Carolina
    Recruiting

  • Conditions:   Stimulant Abuse;   HIV Prevention;   Substance Abuse
    Interventions:   Behavioral: Time & Intensity Matched Control;   Behavioral: IMPACT;   Behavioral: Standard of Care
    Sponsors:   Brown University;   University of Miami;   The Fenway Institute
    Recruiting

  • Conditions:   Schizophrenia;   Substance Abuse;   Cocaine Abuse;   Tobacco Use Disorder
    Intervention:   Behavioral: Various Screening psychiatric and medical assessments
    Sponsor:   University of Maryland
    Recruiting

  • Conditions:   Schizophrenia;   Schizoaffective Disorder;   Substance Use Disorders
    Interventions:   Drug: Brexpiprazole;   Other: Treatment as Usual
    Sponsors:   University of Massachusetts, Worcester;   Massachusetts General Hospital;   University of North Carolina, Chapel Hill;   Otsuka Pharmaceutical Co., Ltd.
    Recruiting

  • Conditions:   Cushing's Disease;   Cushing Syndrome;   Cushing Disease
    Interventions:   Other: Cushing's QoL (Quality of Life Questionnaire);   Other: Nottingham Health Profile (NHP);   Other: Hospital Anxiety and Depression Scale (HADS);   Other: Perceived Stress Scale (PSS);   Other: Barratt's Impulsivity Scale (BIS);   Other: Beck Depression Inventory (BDI);   Other: State-Trait Anxiety Inventory (STAI);   Other: State Food Craving Questionnaire-State (FCQ-S);   Other: Trait Food Craving Questionnaire-Trait (FCQ-T);   Other: Visual Analogue Scale (VAS);   Other: Sensitivity to Reinforcement of Addictive and other Primary Rewards (STRAP-R) food variant
    Sponsor:   Memorial Sloan Kettering Cancer Center
    Recruiting

  • Condition:   Smoking Cessation
    Interventions:   Behavioral: Questionnaires;   Procedure: Low Dose Computed Tomography Scan;   Other: Shared Decision Making + Video;   Behavioral: Cessation Counseling;   Behavioral: Quitline;   Behavioral: Pharmacotherapy Discussion;   Drug: Nicotine Patch;   Drug: Anti-Smoking Drug;   Behavioral: Tobacco Treatment Program;   Other: Carbon Monoxide (CO) Level Test
    Sponsors:   M.D. Anderson Cancer Center;   National Cancer Institute (NCI);   Pfizer
    Recruiting

  • Condition:   Mental and Behavioral Disorders Due to Use of Tobacco
    Interventions:   Procedure: Carbon Monoxide (CO) Testing;   Behavioral: Questionnaires;   Behavioral: Smartphone Assessments;   Other: Urine Sample;   Drug: Usual Brand (UB) Cigarettes;   Other: Very Low Nicotine Content Cigarettes (VLNCC);   Drug: VLNCC and e-cigs (VLNCC+ECIG)
    Sponsors:   M.D. Anderson Cancer Center;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Conditions:   Cancer Prevention;   Tobacco Use Cessation
    Interventions:   Behavioral: Questionnaires;   Behavioral: CO Level Testing;   Behavioral: Behavior Activation Treatment (BAT);   Behavioral: Standard Cessation (SC);   Drug: Nicotine Patch;   Behavioral: Cotinine Level Testing;   Procedure: Lab Session
    Sponsors:   M.D. Anderson Cancer Center;   National Institute on Drug Abuse (NIDA)
    Recruiting

  • Condition:   Eustachian Tube Dysfunction
    Interventions:   Other: ET Stress test;   Other: Sonotubometry;   Other: Forced Response Test (FRT);   Other: Inflation Deflation Test (IDT);   Other: Maneuver Sequence;   Other: 9-Step Test;   Other: Tubomanometry;   Other: Videoendoscopic assessment of ETF;   Other: Pressure chamber ET test
    Sponsors:   University of Pittsburgh;   National Institute on Deafness and Other Communication Disorders (NIDCD)
    Recruiting

Login to Get Started