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  • Conditions:   Spinal Cord Injuries;   Neuropathic Pain
    Interventions:   Drug: Capsaicin 8% Patch;   Drug: Low Dose Capsaicin 0.04% gel
    Sponsor:   The University of Texas Health Science Center at San Antonio
    Recruiting

  • Conditions:   Obesity;   Insulin Resistance
    Interventions:   Dietary Supplement: Capsaicin;   Dietary Supplement: Control
    Sponsor:   George Mason University
    Recruiting

  • Condition:   Cyclical Vomiting
    Interventions:   Drug: Capsaicin 0.075% Cream;   Drug: Placebos
    Sponsor:   Henry Ford Health System
    Recruiting

  • Conditions:   Fibromyalgia;   Pain
    Interventions:   Drug: Capsaicin Patch 8% or 0.1% Capsaicin Cream;   Other: Vehicle Patch
    Sponsor:   University of Florida
    Recruiting

  • Condition:   Healthy
    Interventions:   Drug: Capsaicin;   Device: Videofluoroscopic swallow study
    Sponsors:   University of Florida;   National Institute on Deafness and Other Communication Disorders (NIDCD)
    Recruiting

  • Condition:   Diet, Food Choice, Taste
    Interventions:   Other: Epigallocatechin gallate;   Other: Epigallocatechin gallate control;   Other: Linoleic acid;   Other: Linoleic acid control;   Other: Capsaicin solution;   Other: Capsaicin control
    Sponsors:   Purdue University;   National Institutes of Health (NIH)
    Recruiting

  • Condition:   Parkinson Disease
    Interventions:   Drug: Capsaicin;   Device: Resistive respiratory loads;   Other: Event-related evoked potential using electroencephalography (EEG).;   Procedure: Fluoroscopic swallow evaluation
    Sponsors:   University of Florida;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
    Recruiting

  • Condition:   Oculopharyngeal Muscular Dystrophy
    Interventions:   Device: Iowa Oral Performance Instrument;   Drug: Capsaicin;   Device: Electrical Impedance Myography (EIM);   Procedure: Videofluoroscopic swallowing study;   Other: Swallowing Related Quality of Life Questionnaire;   Other: Functional Oral Intake Scale;   Other: Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised;   Other: Eating Assessment Tool-10;   Other: Communicative Effectiveness Survey;   Other: The Center for Neurologic Studies Bulbar Function Scale
    Sponsor:   University of Florida
    Recruiting

  • Condition:   Amyotrophic Lateral Sclerosis
    Interventions:   Procedure: Videofluoroscopic Swallowing Study (VFSS);   Procedure: High Resolution Manometry;   Other: DIGEST;   Other: Penetration Aspiration Scale;   Other: Normalized Residue Ratio Scale;   Device: Voluntary Peak Cough Flow Testing;   Device: Iowa Oral Performance Instrument;   Drug: Capsaicin Challenge;   Device: Pulmonary Function Testing;   Other: Eating Assessment Tool 10;   Other: The Center for Neurologic Study Bulbar Function Scale
    Sponsors:   University of Florida;   National Institutes of Health (NIH)
    Recruiting

  • Condition:   Osteoarthritis, Knee
    Interventions:   Drug: Placebo;   Drug: CNTX-4975-05 (trans-capsaicin)
    Sponsor:   Centrexion Therapeutics
    Recruiting

  • Conditions:   Intractable Pain;   Palliative Care;   Neoplasm Metastasis;   Questionnaires &Amp; Surveys
    Intervention:   Drug: Resiniferatoxin
    Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
    Recruiting

  • Condition:   Knee Osteoarthritis
    Interventions:   Drug: CNTX-4975-05;   Drug: Lidocaine without epinephrine;   Device: ElastoGel;   Device: Breg Ice Water Pump
    Sponsor:   Centrexion Therapeutics
    Recruiting

  • Conditions:   Pain/Cancer;   Pain, Intractable
    Interventions:   Drug: (Resiniferatoxin)(RTX);   Drug: Intrathecal Resiniferatoxin
    Sponsors:   National Institute of Dental and Craniofacial Research (NIDCR);   National Institute of Neurological Disorders and Stroke (NINDS);   Sorrento Therapeutics, Inc.
    Recruiting

  • Conditions:   Pain;   Alcohol Drinking;   Acute Pain;   Drinking Behavior
    Interventions:   Drug: Low Alcohol;   Drug: Moderate Alcohol;   Drug: Placebo Alcohol;   Other: Pain Induction;   Other: No Pain Induction
    Sponsors:   Syracuse University;   National Institute on Alcohol Abuse and Alcoholism (NIAAA)
    Recruiting

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