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  • Conditions:   Diabetes Mellitus, Type 2;   Hyperuricemia
    Interventions:   Other: Low-fructose diet;   Drug: Allopurinol;   Drug: Placebo
    Sponsor:   University of Missouri-Columbia

  • Condition:   Acute Lymphoblastic Leukemia (ALL)
    Intervention:   Drug: Allopurinol
    Sponsor:   Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

  • Conditions:   Primary Lymphoid Haematopoietic Neoplasms;   Chronic Lymphocytic Leukemia;   Small Lymphocytic Lymphoma
    Interventions:   Drug: Venetoclax;   Drug: Ibrutinib;   Drug: Allopurinol
    Sponsors:   M.D. Anderson Cancer Center;   AbbVie

  • Conditions:   Cardiovascular Diseases;   Cardiovascular Risk Factor;   Vasoconstriction
    Interventions:   Drug: Control (Phenylephrine);   Drug: Phenylephrine + Apocynin;   Drug: Phenylephrine + Allopurinol;   Drug: Phenylephrine + Tempol
    Sponsor:   The University of Texas at Arlington

  • Condition:   Multiple Myeloma
    Interventions:   Drug: Allopurinol;   Drug: Carmustine;   Drug: Etoposide;   Drug: Cytarabine;   Drug: Melphalan
    Sponsor:   Swedish Medical Center

  • Conditions:   Acute Lymphoblastic Leukemia;   Acute Myeloid Leukemia;   Myelodysplastic Syndrome
    Interventions:   Drug: Allopurinol;   Drug: Keppra;   Drug: Busulfan;   Drug: Cyclophosphamide;   Drug: Tacrolimus;   Drug: Mycophenolate mofetil;   Biological: Allogeneic hematopoietic stem cell transplant;   Biological: Filgrastim;   Biological: antithymocyte globulin
    Sponsor:   Masonic Cancer Center, University of Minnesota

  • Conditions:   Gout;   Chronic Kidney Diseases
    Interventions:   Drug: Allopurinol;   Drug: Febuxostat;   Drug: Placebo, vehicle control (Febuxostat-shaped);   Drug: Placebo, vehicle control (Allopurinol-shaped)
    Sponsor:   VA Office of Research and Development

  • Conditions:   Acute Myelogenous Leukemia;   Acute Lymphocytic Leukemia;   Chronic Myelogenous Leukemia;   Plasma Cell Leukemia;   Myelodysplastic Syndromes;   Chronic Lymphocytic Leukemia;   Small Lymphocytic Lymphoma;   B-Cell Lymphoma;   Follicular Lymphoma;   Lymphoplasmacytic Lymphoma;   Mantle-Cell Lymphoma;   Prolymphocytic Leukemia;   Lymphoblastic Lymphoma;   Burkitt's Lymphoma;   Non-Hodgkin's Lymphoma;   Multiple Myeloma;   Myeloproliferative Syndromes;   Hematological Diseases
    Interventions:   Drug: Allopurinol;   Drug: Fludarabine;   Drug: Cyclophosphamide;   Drug: ATG;   Radiation: TBI;   Drug: Tacrolimus;   Drug: MMF;   Biological: Peripheral Blood Stem Cells;   Biological: Related or Unrelated Bone Marrow Cells
    Sponsor:   Masonic Cancer Center, University of Minnesota

  • Condition:   Diabetic Nephropathies
    Interventions:   Other: Mean blood glucose;   Other: Blood glucose CV;   Other: % time 70-180 mg/dL;   Other: % time below 54 mg/dL;   Other: % time above 180 mg/dL;   Other: % time above 250 mg/dL;   Other: MAGE (Mean amplitude of glucose excursions);   Other: LBGI (Low Blood Glucose Index);   Other: HBGI (High Blood Glucose Index);   Drug: Allopurinol;   Drug: Placebo
    Sponsors:   Joslin Diabetes Center;   The Leona M. and Harry B. Helmsley Charitable Trust;   University of Minnesota - Clinical and Translational Science Institute;   University of Colorado, Denver;   University of Michigan;   Feinberg School of Medicine, Northwestern University;   Albert Einstein College of Medicine;   Washington University School of Medicine;   University of Washington;   Providence Medical Research Center

  • Condition:   B Acute Lymphoblastic Leukemia
    Interventions:   Drug: Allopurinol;   Drug: Cytarabine;   Drug: Daunorubicin Hydrochloride;   Drug: Vincristine Sulfate;   Drug: Dexamethasone;   Drug: Pegylated Recombinant L-Asparaginase Erwinia Chrysanthemi;   Drug: Methotrexate;   Procedure: Bone Marrow Aspiration and Biopsy;   Drug: Cyclophosphamide;   Drug: Mercaptopurine;   Biological: Rituximab;   Drug: Doxorubicin;   Drug: Thioguanine;   Biological: Inotuzumab Ozogamicin;   Other: Laboratory Biomarker Analysis
    Sponsors:   Alliance for Clinical Trials in Oncology;   National Cancer Institute (NCI)

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