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  • Conditions:   Complete DiGeorge Anomaly;   DiGeorge Syndrome;   DiGeorge Anomaly;   Complete DiGeorge Syndrome
    Interventions:   Biological: Thymus Tissue for Transplantation;   Procedure: Blood Draw;   Drug: Rabbit anti-thymocyte globulin;   Drug: Cyclosporine;   Drug: Tacrolimus;   Drug: Methylprednisolone or Prednisolone;   Drug: Basiliximab;   Drug: Mycophenolate mofetil
    Sponsors:   M. Louise Markert;   National Institutes of Health (NIH);   National Institute of Allergy and Infectious Diseases (NIAID);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   Enzyvant Therapeutics GmbH
    Available

  • Condition:   Pregnancy
    Intervention:   Diagnostic Test: cfDNA screening
    Sponsor:   University Hospital Tuebingen
    Recruiting

  • Conditions:   Down Syndrome;   Edwards Syndrome;   Patau Syndrome;   Klinefelter Syndrome;   Turner Syndrome;   DiGeorge Syndrome;   Perinatal Infections
    Intervention:   Other: Observational - no intervention
    Sponsor:   Progenity, Inc.
    Recruiting

  • Conditions:   Immune Deficiency Disorders;   Severe Combined Immunodeficiency;   Chronic Granulomatous Disease;   X-linked Agammaglobulinemia;   Wiskott-Aldrich Syndrome;   Hyper-IgM;   DiGeorge Syndrome;   Chediak-Higashi Syndrome;   Common Variable Immune Deficiency;   Immune Dysregulatory Disorders;   Hemophagocytic Lymphohistiocytosis;   IPEX;   Autoimmune Lymphoproliferative Syndrome;   X-linked Lymphoproliferative Syndrome
    Intervention:   Drug: Transplant preparative regimen of alemtuzumab, fludarabine, thiotepa, and melphalan
    Sponsor:   Washington University School of Medicine
    Recruiting

  • Conditions:   Aortopathies;   Thoracic Aortic Aneurysm;   Aortic Valve Disease;   Thoracic Aortic Disease;   Thoracic Aortic Dissection;   Thoracic Aortic Rupture;   Ascending Aortic Disease;   Descending Aortic Disease;   Ascending Aortic Aneurysm;   Descending Aortic Aneurysm;   Marfan Syndrome;   Loeys-Dietz Syndrome;   Ehlers-Danlos Syndrome;   Shprintzen-Goldberg Syndrome;   Turner Syndrome;   PHACE Syndrome;   Autosomal Recessive Cutis Laxa;   Congenital Contractural Arachnodactyly;   Arterial Tortuosity Syndrome
    Intervention:  
    Sponsor:   Indiana University
    Recruiting

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