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  • Condition:   Intraoperative Hypotension
    Interventions:   Device: Acumen HPI-enabled EV1000 screen;   Device: Control
    Sponsor:   The Cleveland Clinic
    Recruiting

  • Condition:   Intracranial Hypotension
    Interventions:   Device: MRI algorithm;   Procedure: Lumbar puncture;   Procedure: Epidural patching
    Sponsors:   Duke University;   University of Miami
    Recruiting

  • Condition:   Orthostatic Hypotension
    Interventions:   Drug: Droxidopa;   Drug: Pyridostigmine Bromide
    Sponsor:   Mayo Clinic
    Recruiting

  • Conditions:   Blood Pressure;   Post-Exercise Hypotension
    Interventions:   Other: High dietary salt;   Other: Placebo
    Sponsor:   University of Delaware
    Recruiting

  • Condition:   Postexercise Hypotension
    Interventions:   Other: Continuous Exercise;   Other: Aerobic Interval Exercise
    Sponsor:   Arizona State University
    Recruiting

  • Conditions:   Sepsis;   Hypotension
    Intervention:   Device: Treatment Starling SV monitor
    Sponsor:   Cheetah Medical Inc.
    Recruiting

  • Condition:   Symptomatic Neurogenic Orthostatic Hypotension
    Interventions:   Drug: TD-9855;   Drug: Placebo
    Sponsor:   Theravance Biopharma
    Recruiting

  • Condition:   Intra-dialytic Hypotension
    Interventions:   Drug: Lower dialysate sodium (138 mmol/L; using Renasol hemodialysis concentrate);   Drug: Higher dialysate sodium (142 mmol/L; using Renasol hemodialysis concentrate)
    Sponsor:   Brigham and Women's Hospital
    Recruiting

  • Conditions:   Orthostatic Hypotension;   Pure Autonomic Failure;   Multiple System Atrophy;   Autonomic Failure
    Interventions:   Other: Abdominal compression;   Other: Sham abdominal compression;   Drug: Placebo pill;   Drug: midodrine
    Sponsor:   Vanderbilt University
    Recruiting

  • Conditions:   Parkinson Disease;   Neurogenic Orthostatic Hypotension
    Interventions:   Drug: Droxidopa;   Drug: Placebo
    Sponsors:   William Ondo, MD;   Lundbeck LLC
    Recruiting

  • Conditions:   Neonatal Prematurity;   Hypotension
    Intervention:   Other: Monitoring and biospecimen collection
    Sponsors:   Baylor College of Medicine;   Texas Children's Hospital;   National Institutes of Health (NIH);   National Heart, Lung, and Blood Institute (NHLBI)
    Recruiting

  • Condition:   Hypotension
    Intervention:   Device: NICOM (Non invasive cardiac output monitor)
    Sponsor:   Mayo Clinic
    Recruiting

  • Conditions:   Parkinson Disease;   Falls Patient
    Interventions:   Drug: Droxidopa;   Other: Placebo
    Sponsors:   St. Joseph's Hospital and Medical Center, Phoenix;   H. Lundbeck A/S;   Arizona State University
    Recruiting

  • Conditions:   Hypotension;   Hypertension
    Interventions:   Device: Non-invasive non-oscillometric blood pressure wristband device;   Device: Invasive intra-arterial blood pressure monitors.
    Sponsor:   New York University School of Medicine
    Recruiting

  • Conditions:   Hypotension;   Sepsis
    Intervention:   Other: Point of Care Ultrasound
    Sponsor:   Yale University
    Recruiting

  • Conditions:   Spinal Cord Injury;   Autonomic Dysreflexia;   Orthostatic Hypotension;   Baroreceptor Integrity;   Sympathetic Integrity;   Vagal Integrity;   Hypotension;   Cerebral Blood Flow;   Blood Pressure;   Venous Occlusion Plethysmography
    Intervention:   Drug: Midodrine Hydrochloride
    Sponsors:   James J. Peters Veterans Affairs Medical Center;   Icahn School of Medicine at Mount Sinai
    Recruiting

  • Condition:   Neurogenic Orthostatic Hypotension
    Interventions:   Drug: Atomoxetine;   Drug: Placebo
    Sponsors:   Vanderbilt University Medical Center;   New York University School of Medicine
    Recruiting

  • Conditions:   Pregnancy Related;   Hypotension, Orthostatic
    Intervention:   Diagnostic Test: Inferior vena cava ultrasound
    Sponsor:   Augusta University
    Recruiting

  • Conditions:   Shock;   Hypotension and Shock
    Intervention:   Device: Measurement by Clearsight device
    Sponsor:   Nemours Children's Clinic
    Recruiting

  • Condition:   Hypertension
    Intervention:   Device: Magnetic field treatment
    Sponsor:   Cardiovascular Therapy LLC
    Recruiting

  • Condition:   Hypotension and Shock
    Intervention:   Other: Lower body negative pressure
    Sponsor:   Mayo Clinic
    Recruiting

  • Conditions:   Orthostatic Hypotension;   Reflex Syncope
    Intervention:   Device: Wearable heart monitor
    Sponsor:   Boston Scientific Corporation
    Not yet recruiting

  • Conditions:   Hypotension, Orthostatic;   Hypotension;   Spinal Cord Injuries
    Intervention:   Drug: Northera
    Sponsors:   James J. Peters Veterans Affairs Medical Center;   New York State Department of Health
    Recruiting

  • Condition:   Cerebrospinal Fluid Leaks
    Intervention:   Drug: TISSEEL
    Sponsor:   Duke University
    Recruiting

  • Conditions:   Septic Shock;   Hypotension;   Tachycardia
    Interventions:   Drug: Esmolol;   Other: Saline
    Sponsors:   Beth Israel Deaconess Medical Center;   American Heart Association
    Recruiting

  • Conditions:   Low Blood Pressure;   Delirium;   Critical Illness
    Intervention:   Other: sedation awakening trial
    Sponsor:   University of Chicago
    Recruiting

  • Conditions:   Multiple System Atrophy;   Orthostatic Hypotension;   Supine Hypertension
    Interventions:   Drug: Trimethaphan;   Drug: Placebo
    Sponsor:   Vanderbilt University
    Recruiting

  • Condition:   Cardiac Arrest
    Intervention:   Device: RUSH Exam
    Sponsor:   University of Florida
    Recruiting

  • Condition:   Vasoplegic Syndrome
    Interventions:   Drug: Hydroxocobalamin;   Procedure: Cardiopulmonary Bypass;   Drug: Placebos
    Sponsor:   Mayo Clinic
    Recruiting

  • Condition:   Hypertension
    Intervention:   Drug: Angiotensin II
    Sponsor:   Wake Forest University Health Sciences
    Not yet recruiting

  • Conditions:   Vasoplegia;   Hypotension;   Coronary Artery Disease;   Cardiac Valve Disease
    Interventions:   Drug: Hydroxocobalamin;   Drug: Methylene Blue;   Drug: Normal saline
    Sponsor:   Dartmouth-Hitchcock Medical Center
    Not yet recruiting

  • Condition:   Septic Shock
    Interventions:   Drug: Midodrine Hydrochloride;   Other: placebo
    Sponsor:   University of Virginia
    Recruiting

  • Conditions:   Autonomic Nervous System Disorders;   Pure Autonomic Failure;   Shy-Drager Syndrome;   Orthostatic Hypotension, Dysautonomic
    Interventions:   Drug: Angiotensin-(1-7);   Drug: Saline
    Sponsor:   Vanderbilt University
    Recruiting

  • Condition:   Atrial Fibrillation
    Intervention:   Device: Cryoballoon ablation
    Sponsor:   Alan P. Wimmer, MD
    Recruiting

  • Conditions:   Chronic Autonomic Failure;   Parkinson Disease With Orthostatic Hypotension;   Dementia With Lewy Bodies;   Orthostatic Hypotension;   Multiple System Atrophy;   Iatrogenic Chronic Autonomic Failure
    Intervention:  
    Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
    Recruiting

  • Conditions:   Autonomic Failure;   Pure Autonomic Failure;   Multiple System Atrophy;   Parkinson Disease;   Orthostatic Hypotension
    Interventions:   Drug: Droxidopa;   Drug: Midodrine;   Drug: Placebo
    Sponsor:   Vanderbilt University Medical Center
    Recruiting

  • Condition:   Symptomatic Neurogenic Orthostatic Hypotension
    Interventions:   Drug: TD-9855;   Drug: Placebo
    Sponsor:   Theravance Biopharma
    Recruiting

  • Condition:   Hypotension
    Intervention:   Drug: Phenylephrine
    Sponsor:   West-Ward Pharmaceutical
    Recruiting

  • Conditions:   Systemic Inflammatory Response Syndrome;   Distributive Shock;   Hypotension and Shock;   Decompensated Congestive Heart Failure;   Atrial Fibrillation;   High Risk Non-cardiac Surgery
    Interventions:   Procedure: Peripheral Intravenous Analysis (PIVA);   Procedure: Standard of care invasive vascular monitoring;   Procedure: Standard noninvasive vascular monitoring
    Sponsors:   Vanderbilt University Medical Center;   Baxter Healthcare Corporation
    Recruiting

  • Conditions:   Acute Respiratory Failure;   Intubation Complication;   Hypotension on Induction
    Interventions:   Drug: Fluid Bolus;   Other: No Fluid Bolus
    Sponsor:   Vanderbilt University Medical Center
    Recruiting

  • Conditions:   Spinal Cord Injury;   Autonomic Dysreflexia;   Baroreceptor Integrity;   Sympathetic Integrity;   Vagal Integrity;   Autonomic Integrity;   Hypotensive;   Cognitive Function;   Cerebral Blood Flow;   Blood Pressure
    Interventions:   Drug: Midodrine Hydrochloride;   Drug: Pyridostigmine Bromide;   Drug: Mirabegron;   Other: Placebo
    Sponsors:   James J. Peters Veterans Affairs Medical Center;   Kessler Foundation
    Recruiting

  • Conditions:   Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy;   Autonomic Failure
    Interventions:   Other: Heating pad;   Other: Sham control
    Sponsor:   Vanderbilt University Medical Center
    Recruiting

  • Conditions:   Hypertension;   Pure Autonomic Failure;   Multiple System Atrophy;   Autonomic Failure
    Interventions:   Other: Passive heat stress;   Other: Control (non-heating)
    Sponsor:   Vanderbilt University
    Recruiting

  • Conditions:   Neurologic Disorders;   Nervous System Diseases;   Neurodegenerative Diseases;   Neurological Disorders;   Stroke;   Traumatic Brain Injury;   Cadasil;   Chronic Traumatic Encephalopathy;   Cerebral Infarction;   Cerebral Ischemia;   Cerebral Stroke;   Cerebral Hemorrhage;   Parkinson;   Multi-System Degeneration;   MSA - Multiple System Atrophy;   Progressive Supranuclear Palsy;   ALS;   Amyotrophic Lateral Sclerosis;   Neuropathy;   Diabetic Neuropathies
    Interventions:   Procedure: Intravenous BMSC;   Procedure: Intranasal BMSC
    Sponsors:   MD Stem Cells;   The Healing Institute
    Recruiting

  • Conditions:   Patients With Synucleinopathies;   Neurogenic Orthostatic Hypotension;   Pure Autonomic Failure;   REM Sleep Behavior Disorder;   Parkinson Disease;   Dementia With Lewy Bodies;   Multiple System Atrophy;   Shy-Drager Disease
    Intervention:  
    Sponsor:   New York University School of Medicine
    Recruiting

  • Condition:   Multiple System Atrophy (MSA)
    Intervention:  
    Sponsor:   University of Texas Southwestern Medical Center
    Recruiting

  • Condition:   Multiple System Atrophy
    Interventions:   Drug: Sirolimus 2 MG;   Other: Placebo
    Sponsors:   New York University School of Medicine;   National Institute of Neurological Disorders and Stroke (NINDS)
    Recruiting

  • Conditions:   Progressive Supranuclear Palsy;   Dementia With Lewy Bodies;   Multiple System Atrophy;   Corticobasal Syndrome;   Atypical Parkinson Disease
    Interventions:   Behavioral: Home Visit Program;   Behavioral: Usual Care/Online Survey
    Sponsor:   Rush University Medical Center
    Recruiting

  • Conditions:   Parkinson's Disease;   Parkinsonian Disorders;   Atypical Parkinson Disease;   Progressive Supranuclear Palsy;   Multiple System Atrophy;   Corticobasal Degeneration;   Gait, Frontal
    Interventions:   Drug: Anti-Parkinson medication;   Device: Deep Brain Stimulation
    Sponsor:   Beth Israel Deaconess Medical Center
    Recruiting

  • Condition:   Multiple System Atrophy (MSA)
    Interventions:   Drug: Atomexetine;   Drug: Placebo
    Sponsors:   New York University School of Medicine;   Vanderbilt University Medical Center
    Recruiting

  • Conditions:   Parkinson Disease;   Multiple System Atrophy;   REM Sleep Behavior Disorder;   Pure Autonomic Failure;   Dementia With Lewy Bodies
    Intervention:  
    Sponsors:   New York University School of Medicine;   Michael J. Fox Foundation for Parkinson's Research
    Recruiting

  • Conditions:   Ataxia;   Dystonia;   Parkinson's Disease;   Amyotrophic Lateral Sclerosis;   Corticobasal Degeneration;   Multiple System Atrophy;   Alzheimer's Disease;   Lewy Body Dementia;   Parkinson Disease-Dementia;   Dentatorubral-pallidoluysian Atrophy;   Creutzfeldt-Jakob Disease and Fatal Familial Insomnia;   Fragile X-associated Tremor/Ataxia Syndrome;   Krabbe's Disease;   Niemann-Pick Disease, Type C;   Neuronal Ceroid Lipofuscinosis
    Intervention:  
    Sponsor:   National Institute on Aging (NIA)
    Recruiting

  • Conditions:   Parkinson Disease;   Parkinsonism;   Lewy Body Disease;   Supranuclear Palsy, Progressive;   Parkinsonism Vascular;   Multiple System Atrophy;   Corticobasal Degeneration
    Intervention:   Behavioral: Palliative Care
    Sponsors:   University of Colorado, Denver;   National Institute of Nursing Research (NINR);   University of California, San Francisco
    Recruiting

  • Conditions:   Rare Disorders;   Undiagnosed Disorders;   Disorders of Unknown Prevalence;   Cornelia De Lange Syndrome;   Prenatal Benign Hypophosphatasia;   Perinatal Lethal Hypophosphatasia;   Odontohypophosphatasia;   Adult Hypophosphatasia;   Childhood-onset Hypophosphatasia;   Infantile Hypophosphatasia;   Hypophosphatasia;   Kabuki Syndrome;   Bohring-Opitz Syndrome;   Narcolepsy Without Cataplexy;   Narcolepsy-cataplexy;   Hypersomnolence Disorder;   Idiopathic Hypersomnia Without Long Sleep Time;   Idiopathic Hypersomnia With Long Sleep Time;   Idiopathic Hypersomnia;   Kleine-Levin Syndrome;   Kawasaki Disease;   Leiomyosarcoma;   Leiomyosarcoma of the Corpus Uteri;   Leiomyosarcoma of the Cervix Uteri;   Leiomyosarcoma of Small Intestine;   Acquired Myasthenia Gravis;   Addison Disease;   Hyperacusis (Hyperacousis);   Juvenile Myasthenia Gravis;   Transient Neonatal Myasthenia Gravis;   Williams Syndrome;   Lyme Disease;   Myasthenia Gravis;   Marinesco Sjogren Syndrome(Marinesco-Sjogren Syndrome);   Isolated Klippel-Feil Syndrome;   Frasier Syndrome;   Denys-Drash Syndrome;   Beckwith-Wiedemann Syndrome;   Emanuel Syndrome;   Isolated Aniridia;   Beckwith-Wiedemann Syndrome Due to Paternal Uniparental Disomy of Chromosome 11;   Beckwith-Wiedemann Syndrome Due to Imprinting Defect of 11p15;   Beckwith-Wiedemann Syndrome Due to 11p15 Translocation/Inversion;   Beckwith-Wiedemann Syndrome Due to 11p15 Microduplication;   Beckwith-Wiedemann Syndrome Due to 11p15 Microdeletion;   Axenfeld-Rieger Syndrome;   Aniridia-intellectual Disability Syndrome;   Aniridia - Renal Agenesis - Psychomotor Retardation;   Aniridia - Ptosis - Intellectual Disability - Familial Obesity;   Aniridia - Cerebellar Ataxia - Intellectual Disability;   Aniridia - Absent Patella;   Aniridia;   Peters Anomaly - Cataract;   Peters Anomaly;   Potocki-Shaffer Syndrome;   Silver-Russell Syndrome Due to Maternal Uniparental Disomy of Chromosome 11;   Silver-Russell Syndrome Due to Imprinting Defect of 11p15;   Silver-Russell Syndrome Due to 11p15 Microduplication;   Syndromic Aniridia;   WAGR Syndrome;   Wolf-Hirschhorn Syndrome;   4p16.3 Microduplication Syndrome;   4p Deletion Syndrome, Non-Wolf-Hirschhorn Syndrome;   Autosomal Recessive Stickler Syndrome;   Stickler Syndrome Type 2;   Stickler Syndrome Type 1;   Stickler Syndrome;   Mucolipidosis Type 4;   X-linked Spinocerebellar Ataxia Type 4;   X-linked Spinocerebellar Ataxia Type 3;   X-linked Intellectual Disability - Ataxia - Apraxia;   X-linked Progressive Cerebellar Ataxia;   X-linked Non Progressive Cerebellar Ataxia;   X-linked Cerebellar Ataxia;   Vitamin B12 Deficiency Ataxia;   Toxic Exposure Ataxia;   Unclassified Autosomal Dominant Spinocerebellar Ataxia;   Thyroid Antibody Ataxia;   Sporadic Adult-onset Ataxia of Unknown Etiology;   Spinocerebellar Ataxia With Oculomotor Anomaly;   Spinocerebellar Ataxia With Epilepsy;   Spinocerebellar Ataxia With Axonal Neuropathy Type 2;   Spinocerebellar Ataxia Type 8;   Spinocerebellar Ataxia Type 7;   Spinocerebellar Ataxia Type 6;   Spinocerebellar Ataxia Type 5;   Spinocerebellar Ataxia Type 4;   Spinocerebellar Ataxia Type 37;   Spinocerebellar Ataxia Type 36;   Spinocerebellar Ataxia Type 35;   Spinocerebellar Ataxia Type 34;   Spinocerebellar Ataxia Type 32;   Spinocerebellar Ataxia Type 31;   Spinocerebellar Ataxia Type 30;   Spinocerebellar Ataxia Type 3;   Spinocerebellar Ataxia Type 29;   Spinocerebellar Ataxia Type 28;   Spinocerebellar Ataxia Type 27;   Spinocerebellar Ataxia Type 26;   Spinocerebellar Ataxia Type 25;   Spinocerebellar Ataxia Type 23;   Spinocerebellar Ataxia Type 22;   Spinocerebellar Ataxia Type 21;   Spinocerebellar Ataxia Type 20;   Spinocerebellar Ataxia Type 2;   Spinocerebellar Ataxia Type 19/22;   Spinocerebellar Ataxia Type 18;   Spinocerebellar Ataxia Type 17;   Spinocerebellar Ataxia Type 16;   Spinocerebellar Ataxia Type 15/16;   Spinocerebellar Ataxia Type 14;   Spinocerebellar Ataxia Type 13;   Spinocerebellar Ataxia Type 12;   Spinocerebellar Ataxia Type 11;   Spinocerebellar Ataxia Type 10;   Spinocerebellar Ataxia Type 1 With Axonal Neuropathy;   Spinocerebellar Ataxia Type 1;   Spinocerebellar Ataxia - Unknown;   Spinocerebellar Ataxia - Dysmorphism;   Non Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature;   Spectrin-associated Autosomal Recessive Cerebellar Ataxia;   Spasticity-ataxia-gait Anomalies Syndrome;   Spastic Ataxia With Congenital Miosis;   Spastic Ataxia - Corneal Dystrophy;   Spastic Ataxia;   Rare Hereditary Ataxia;   Rare Ataxia;   Recessive Mitochondrial Ataxia Syndrome;   Progressive Epilepsy and/or Ataxia With Myoclonus as a Major Feature;   Posterior Column Ataxia - Retinitis Pigmentosa;   Post-Stroke Ataxia;   Post-Head Injury Ataxia;   Post Vaccination Ataxia;   Polyneuropathy - Hearing Loss - Ataxia - Retinitis Pigmentosa - Cataract;   Muscular Atrophy - Ataxia - Retinitis Pigmentosa - Diabetes Mellitus;   Non-progressive Cerebellar Ataxia With Intellectual Disability;   Non-hereditary Degenerative Ataxia;   Paroxysmal Dystonic Choreathetosis With Episodic Ataxia and Spasticity;   Olivopontocerebellar Atrophy - Deafness;   NARP Syndrome;   Myoclonus - Cerebellar Ataxia - Deafness;   Multiple System Atrophy, Parkinsonian Type;   Multiple System Atrophy, Cerebellar Type;   Multiple System Atrophy;   Maternally-inherited Leigh Syndrome;   Machado-Joseph Disease Type 3;   Machado-Joseph Disease Type 2;   Machado-Joseph Disease Type 1;   Lethal Ataxia With Deafness and Optic Atrophy;   Leigh Syndrome;   Leukoencephalopathy With Mild Cerebellar Ataxia and White Matter Edema;   Leukoencephalopathy - Ataxia - Hypodontia - Hypomyelination;   Leigh Syndrome With Nephrotic Syndrome;   Leigh Syndrome With Leukodystrophy;   Leigh Syndrome With Cardiomyopathy;   Late-onset Ataxia With Dementia;   Intellectual Disability-hyperkinetic Movement-truncal Ataxia Syndrome;   Infection or Post Infection Ataxia;   Infantile-onset Autosomal Recessive Nonprogressive Cerebellar Ataxia;   Infantile Onset Spinocerebellar Ataxia;   GAD Ataxia;   Hereditary Episodic Ataxia;   Gliadin/Gluten Ataxia;   Friedreich Ataxia;   Fragile X-associated Tremor/Ataxia Syndrome;   Familial Paroxysmal Ataxia;   Exposure to Medications Ataxia;   Episodic Ataxia With Slurred Speech;   Episodic Ataxia Unknown Type;   Episodic Ataxia Type 7;   Episodic Ataxia Type 6;   Episodic Ataxia Type 5;   Episodic Ataxia Type 4;   Episodic Ataxia Type 3;   Episodic Ataxia Type 1;   Epilepsy and/or Ataxia With Myoclonus as Major Feature;   Early-onset Spastic Ataxia-neuropathy Syndrome;   Early-onset Progressive Neurodegeneration - Blindness - Ataxia - Spasticity;   Early-onset Cerebellar Ataxia With Retained Tendon Reflexes;   Early-onset Ataxia With Dementia;   Childhood-onset Autosomal Recessive Slowly Progressive Spinocerebellar Ataxia;   Dilated Cardiomyopathy With Ataxia;   Cataract - Ataxia - Deafness;   Cerebellar Ataxia, Cayman Type;   Cerebellar Ataxia With Peripheral Neuropathy;   Cerebellar Ataxia - Hypogonadism;   Cerebellar Ataxia - Ectodermal Dysplasia;   Cerebellar Ataxia - Areflexia - Pes Cavus - Optic Atrophy - Sensorineural Hearing Loss;   Brain Tumor Ataxia;   Brachydactyly - Nystagmus - Cerebellar Ataxia;   Benign Paroxysmal Tonic Upgaze of Childhood With Ataxia;   Autosomal Recessive Syndromic Cerebellar Ataxia;   Autosomal Recessive Spastic Ataxia With Leukoencephalopathy;   Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay;   Autosomal Recessive Spastic Ataxia - Optic Atrophy - Dysarthria;   Autosomal Recessive Spastic Ataxia;   Autosomal Recessive Metabolic Cerebellar Ataxia;   Autosomal Dominant Spinocerebellar Ataxia Due to Repeat Expansions That do Not Encode Polyglutamine;   Autosomal Recessive Ataxia, Beauce Type;   Autosomal Recessive Ataxia Due to Ubiquinone Deficiency;   Autosomal Recessive Ataxia Due to PEX10 Deficiency;   Autosomal Recessive Degenerative and Progressive Cerebellar Ataxia;   Autosomal Recessive Congenital Cerebellar Ataxia Due to MGLUR1 Deficiency;   Autosomal Recessive Congenital Cerebellar Ataxia Due to GRID2 Deficiency;   Autosomal Recessive Congenital Cerebellar Ataxia;   Autosomal Recessive Cerebellar Ataxia-pyramidal Signs-nystagmus-oculomotor Apraxia Syndrome;   Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to WWOX Deficiency;   Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to TUD Deficiency;   Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome Due to KIAA0226 Deficiency;   Autosomal Recessive Cerebellar Ataxia-epilepsy-intellectual Disability Syndrome;   Autosomal Recessive Cerebellar Ataxia With Late-onset Spasticity;   Autosomal Recessive Cerebellar Ataxia Due to STUB1 Deficiency;   Autosomal Recessive Cerebellar Ataxia Due to a DNA Repair Defect;   Autosomal Recessive Cerebellar Ataxia - Saccadic Intrusion;   Autosomal Recessive Cerebellar Ataxia - Psychomotor Retardation;   Autosomal Recessive Cerebellar Ataxia - Blindness - Deafness;   Autosomal Recessive Cerebellar Ataxia;   Autosomal Dominant Spinocerebellar Ataxia Due to a Polyglutamine Anomaly;   Autosomal Dominant Spinocerebellar Ataxia Due to a Point Mutation;   Autosomal Dominant Spinocerebellar Ataxia Due to a Channelopathy;   Autosomal Dominant Spastic Ataxia Type 1;   Autosomal Dominant Spastic Ataxia;   Autosomal Dominant Optic Atrophy;   Ataxia-telangiectasia Variant;   Ataxia-telangiectasia;   Autosomal Dominant Cerebellar Ataxia, Deafness and Narcolepsy;   Autosomal Dominant Cerebellar Ataxia Type 4;   Autosomal Dominant Cerebellar Ataxia Type 3;   Autosomal Dominant Cerebellar Ataxia Type 2;   Autosomal Dominant Cerebellar Ataxia Type 1;   Autosomal Dominant Cerebellar Ataxia;   Ataxia-telangiectasia-like Disorder;   Ataxia-intellectual Disability-oculomotor Apraxia-cerebellar Cysts Syndrome;   Ataxia-deafness-intellectual Disability Syndrome;   Ataxia With Vitamin E Deficiency;   Ataxia With Dementia;   Ataxia Neuropathy Spectrum;   Ataxia - Tapetoretinal Degeneration;   Ataxia - Photosensitivity - Short Stature;   Ataxia - Pancytopenia;   Ataxia - Oculomotor Apraxia Type 1;   Ataxia - Hypogonadism - Choroidal Dystrophy;   Ataxia - Other;   Ataxia - Genetic Diagnosis - Unknown;   Acquired Ataxia;   Adult-onset Autosomal Recessive Cerebellar Ataxia;   Alcohol Related Ataxia;   Multiple Endocrine Neoplasia;   Multiple Endocrine Neoplasia Type II;   Multiple Endocrine Neoplasia Type 1;   Multiple Endocrine Neoplasia Type 2;   Multiple Endocrine Neoplasia, Type IV;   Multiple Endocrine Neoplasia, Type 3;   Multiple Endocrine Neoplasia (MEN) Syndrome;   Multiple Endocrine Neoplasia Type 2B;   Multiple Endocrine Neoplasia Type 2A;   Atypical Hemolytic Uremic Syndrome;   Atypical HUS;   Wiedemann-Steiner Syndrome;   Breast Implant-Associated Anaplastic Large Cell Lymphoma;   Autoimmune/Inflammatory Syndrome Induced by Adjuvants (ASIA);   Hemophagocytic Lymphohistiocytosis;   Behcet's Disease;   Alagille Syndrome;   Inclusion Body Myopathy With Early-onset Paget Disease and Frontotemporal Dementia (IBMPFD);   Lowe Syndrome;   Pitt Hopkins Syndrome;   1p36 Deletion Syndrome;   Jansen Type Metaphyseal Chondrodysplasia;   Cockayne Syndrome;   Chronic Recurrent Multifocal Osteomyelitis;   CRMO;   Malan Syndrome;   Hereditary Sensory and Autonomic Neuropathy Type Ie
    Intervention:  
    Sponsors:   Sanford Health;   National Ataxia Foundation;   International WAGR Syndrome Association;   4p- Support Group;   ML4 Foundation;   Cornelia de Lange Syndrome Foundation;   Stickler Involved People;   Kawasaki Disease Foundation;   Klippel-Feil Syndrome Alliance;   Klippel-Feil Syndrome Freedom;   Hyperacusis Research Limited;   Hypersomnia Foundation;   Kabuki Syndrome Network;   Kleine-Levin Syndrome Foundation;   Leiomyosarcoma Direct Research Foundation;   Marinesco-Sjogren Syndrome Support Group;   Mucolipidosis Type IV (ML4) Foundation;   People with Narcolepsy 4 People with Narcolepsy (PWN4PWN);   Soft Bones Incorporated;   American Multiple Endocrine Neoplasia Support;   Atypical Hemolytic Uremic Syndrome Foundation;   All Things Kabuki;   Wiedemann-Steiner Syndrome Foundation;   Breast Implant Victim Advocates;   PROS Foundation;   American Behcet's Disease Association
    Recruiting

  • Conditions:   Blood Pressure;   Heart Failure;   Advanced Heart Failure;   Heart Failure,Congestive
    Intervention:   Device: Wrist-worn measurement device (LiveMetric)
    Sponsor:   LiveMetric S.A.
    Recruiting

  • Conditions:   Blood Pressure;   Heart Failure;   Advanced Heart Failure;   Heart Failure,Congestive
    Intervention:   Device: Wrist-worn measurement device (LiveMetric)
    Sponsor:   University of Chicago
    Recruiting

  • Condition:   Spinal Cord Injury
    Interventions:   Drug: Midodrine;   Drug: Placebo
    Sponsors:   James J. Peters Veterans Affairs Medical Center;   Kessler Foundation
    Recruiting

  • Condition:   Septic Shock
    Interventions:   Drug: Early Vasopressors;   Drug: Early Fluids
    Sponsor:   Massachusetts General Hospital
    Recruiting

  • Condition:   Sepsis
    Interventions:   Procedure: ECHO;   Procedure: Blood Draw
    Sponsors:   Intermountain Health Care, Inc.;   Beth Israel Deaconess Medical Center;   Montefiore Medical Center;   Oregon Health and Science University;   Vanderbilt University Medical Center;   Wake Forest University Health Sciences needs to be deleted;   Harborview Injury Prevention and Research Center
    Not yet recruiting

  • Conditions:   REM Sleep Behavior Disorder;   Parkinson Disease;   Lewy Body Disease;   Dementia With Lewy Bodies;   Multiple System Atrophy;   REM Sleep Parasomnias
    Intervention:  
    Sponsors:   Washington University School of Medicine;   Mayo Clinic;   University of Minnesota - Clinical and Translational Science Institute;   University of California, Los Angeles;   McGill University;   Emory University;   Massachusetts General Hospital;   National Institute on Aging (NIA)
    Recruiting

  • Conditions:   Perioperative Bleeding;   Venous Thrombosis;   Arterial Thrombosis
    Interventions:   Drug: Tranexamic Acid;   Drug: Placebo (Saline);   Other: Perioperative hypotension-avoidance strategy;   Other: Perioperative hypertension-avoidance strategy
    Sponsor:   Population Health Research Institute
    Recruiting

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