JoinClinicalTrials.com

Results

Hot

Post your clinical trial on JoinClinicalTrials.com

Ellijay, Georgia 30536
United States

Post your clinical trial on JoinClinicalTrials.com to reach thousands of viewer daily. Our Clinical Trial Listings have consistently proven to be an ...

• Mindfulness for at Risk Youth: Understanding Substance Use and Important Mechanisms of Change

  NCT04160754

  Conditions:   Alcohol Use, Underage;   Alcohol Problem Drinking;   Substance Use
  Interventions:   Behavioral: Mindfulness Based Relapse Prevention;   Behavioral: Control (CTL)
  Sponsor:   University of Southern California
  Recruiting
• Advancing Postmenopausal Preventive Therapy

  NCT04103476

  Conditions:   Atherosclerosis;   Cognitive Decline
  Interventions:   Combination Product: Oral bazedoxifene 20 mg / conjugated estrogens 0.45 mg;   Other: Placebo
  Sponsors:   University of Southern California;   National Institute on Aging (NIA)
  Recruiting
• Evaluation of an Intervention for Young Adults With Diabetes: Resilient, Empowered, Active Living-Telehealth (REAL-T)

  NCT04023487

  Condition:   Diabetes Mellitus, Type 1
  Intervention:   Behavioral: Resilient, Empowered, Active Living-Telehealth (REAL-T)
  Sponsors:   University of Southern California;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  Recruiting
• Smoking and Ventricular Repolarization

  NCT03916341

  Conditions:   Sudden Cardiac Death;   Prolonged QTc Interval
  Interventions:   Other: EC with nicotine;   Other: EC without nicotine;   Other: control;   Other: TC with nicotine (own brand);   Other: research TC with very low level nicotine
  Sponsors:   University of California, Los Angeles;   Tobacco Related Disease Research Program
  Recruiting
• Effects of Inflammation on Affect and Behavior

  NCT03848715

  Conditions:   Anhedonia;   Depression
  Interventions:   Biological: Endotoxin;   Biological: Placebo
  Sponsor:   University of California, Los Angeles
  Recruiting
• Transcranial Direct Current Stimulation in Major Depression

  NCT03556124

  Condition:   Major Depressive Disorder
  Interventions:   Device: Active - HD tDCS;   Device: Sham - HD tDCS;   Device: Active - Conventional tDCS;   Device: Sham - Conventional tDCS
  Sponsors:   University of California, Los Angeles;   National Institute of Mental Health (NIMH)
  Recruiting
• Ibudilast and Withdrawal-Related Dysphoria

  NCT03489850

  Condition:   Alcohol Use Disorder
  Interventions:   Drug: Ibudilast;   Other: Placebo
  Sponsor:   University of California, Los Angeles
  Recruiting
• Enhancing Cognitive Training Through Exercise Following a First Schizophrenia Episode

  NCT02823041

  Conditions:   Schizophrenia;   Schizophreniform Disorder;   Schizoaffective Disorder
  Interventions:   Behavioral: Cognitive Training;   Behavioral: Aerobic Exercise;   Behavioral: Case management and supportive psychotherapy;   Behavioral: Individual Placement and Support
  Sponsor:   University of California, Los Angeles
  Recruiting
• PEERS© for Careers

  NCT04114942

  Condition:   Autism Spectrum Disorder
  Interventions:   Behavioral: Never Coach;   Behavioral: Internship Only Coach;   Behavioral: Didactic Only Coach;   Behavioral: Constant Coach
  Sponsor:   University of California, Los Angeles
  Recruiting
• Affective Management Training for Cannabis Misuse

  NCT03432013

  Condition:   Cannabis Use Disorder
  Interventions:   Behavioral: CUD-AMT;   Behavioral: SUD-CBT
  Sponsors:   University of California, Los Angeles;   National Institute on Drug Abuse (NIDA)
  Recruiting
• Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS Women

  NCT01889199

  Condition:   Polycystic Ovary Syndrome (PCOS)
  Interventions:   Drug: Flutamide;   Other: Placebo
  Sponsors:   University of California, Los Angeles;   Oregon Health and Science University
  Recruiting
• Socially Assistive Robots to Enhance Magnification Device Use for Reading

  NCT04190134

  Condition:   Low Vision
  Intervention:   Behavioral: Socially Assistive Robot for Low Vision Rehabilitation
  Sponsors:   University of California, Los Angeles;   University of Southern California
  Recruiting
• A Mind-Body Intervention for Chemotherapy-Induced Peripheral Neuropathy

  NCT04185610

  Conditions:   Chemotherapy-induced Peripheral Neuropathy;   Cancer
  Intervention:   Other: Qi Gong
  Sponsor:   Arash Asher, MD
  Recruiting
• Ipilimumab, Nivolumab, and Talimogene Laherparepvec Before Surgery in Treating Participants With Localized, Triple-Negative or Estrogen Receptor Positive, HER2 Negative Breast Cancer-deleted

  NCT04185311

  Conditions:   Anatomic Stage 0 Breast Cancer AJCC v8;   Anatomic Stage I Breast Cancer AJCC v8;   Anatomic Stage IA Breast Cancer AJCC v8;   Anatomic Stage IB Breast Cancer AJCC v8;   Anatomic Stage II Breast Cancer AJCC v8;   Anatomic Stage IIA Breast Cancer AJCC v8;   Anatomic Stage IIB Breast Cancer AJCC v8;   Anatomic Stage IIIA Breast Cancer AJCC v8;   Anatomic Stage IIIB Breast Cancer AJCC v8;   HER2/Neu Negative;   Invasive Ductal Carcinoma, Not Otherwise Specified;   Progesterone Receptor Negative;   Prognostic Stage 0 Breast Cancer AJCC v8;   Prognostic Stage I Breast Cancer AJCC v8;   Prognostic Stage IA Breast Cancer AJCC v8;   Prognostic Stage IB Breast Cancer AJCC v8;   Prognostic Stage II Breast Cancer AJCC v8;   Prognostic Stage IIA Breast Cancer AJCC v8;   Prognostic Stage IIB Breast Cancer AJCC v8;   Prognostic Stage IIIA Breast Cancer AJCC v8;   Prognostic Stage IIIB Breast Cancer AJCC v8;   Triple-Negative Breast Carcinoma
  Interventions:   Biological: Ipilimumab;   Biological: Nivolumab;   Biological: Talimogene Laherparepvec
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• Pudendal Enhancement of Enhanced Recovery After Surgery (ERAS) for Reconstructive Surgery (PEERS)

  NCT04171050

  Condition:   Pain Management
  Interventions:   Drug: Local anaesthetic;   Drug: Pudendal Nerve Block plus anesthesia
  Sponsor:   University of California, Los Angeles
  Recruiting
• Mindfulness Meditation and Bariatric Surgery

  NCT04167852

  Conditions:   Opioid Use;   Bariatric Surgery Candidate;   Pain, Postoperative
  Interventions:   Behavioral: Daily text message;   Behavioral: Mindfulness intervention
  Sponsor:   Cedars-Sinai Medical Center
  Recruiting
• NOrth American Study for the Treatment of Recurrent epIstaxis With DoxycycLine: The NOSTRIL Trial

  NCT04167085

  Condition:   Epistaxis
  Interventions:   Drug: Doxycycline;   Other: Placebo
  Sponsor:   University of California, Los Angeles
  Recruiting
• Single Anastomosis Duodenal Ileal Bypass (SADI) for Sleeve Revision

  NCT04165694

  Conditions:   Bariatric Surgery Candidate;   Severe Obesity
  Intervention:   Procedure: Single Anastomosis Duodenal Ileal Bypass (SADI)
  Sponsor:   Kaiser Permanente
  Recruiting
• Study With Lu AF87908 in Healthy Subjects and Patients With Alzheimer's Disease

  NCT04149860

  Conditions:   Healthy;   Alzheimer Disease
  Interventions:   Drug: Lu AF87908;   Drug: Placebo
  Sponsor:   H. Lundbeck A/S
  Recruiting
• Arbitration Between Habitual and Goal-directed Behavior in Obsessive-compulsive Disorder: Circuit Dynamics and Effects of Noninvasive Neurostimulation

  NCT04075890

  Conditions:   OCD;   Decision-Making;   tDCS;   fMRI
  Intervention:   Device: transcranial Direct Current Stimulation (tDCS)
  Sponsor:   University of California, Los Angeles
  Recruiting
• OsteoCrete in Filling Bone Voids in Participants With Bone Voids or Defects

  NCT04069923

  Condition:   Health Status Unknown
  Intervention:   Other: Magnesium-based Bone Void Filler
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• Transcranial Direct Current Stimulation as a Neuroprotection in Acute Stroke Before and After Thrombectomy

  NCT04061577

  Condition:   Acute Ischemic Stroke
  Intervention:   Device: Transcranial Direct Current Stimulation (tDCS)
  Sponsors:   University of California, Los Angeles;   The City College of New York
  Recruiting
• 68GA-PSMA-11 PET/CT Scan in Impacting Treatment Strategies for Patients With Prostate Cancer

  NCT04050215

  Conditions:   Biochemically Recurrent Prostate Carcinoma;   Metastatic Prostate Carcinoma;   Prostate Adenocarcinoma;   Prostate Carcinoma;   PSA Level Greater Than Fifty;   PSA Progression;   Stage IV Prostate Cancer AJCC v8;   Stage IVA Prostate Cancer AJCC v8;   Stage IVB Prostate Cancer AJCC v8
  Interventions:   Procedure: Computed Tomography;   Drug: Gallium Ga 68-labeled PSMA-11;   Procedure: Positron Emission Tomography;   Other: Questionnaire Administration
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• Optimizing Exposure Therapy for Anxiety Disorders

  NCT04048824

  Conditions:   Social Anxiety Disorder;   Panic Disorder
  Interventions:   Behavioral: Inhibitory Learning-Based Exposure;   Behavioral: Habituation-Based Exposure
  Sponsor:   University of California, Los Angeles
  Recruiting
• Developing Dynamic Theories for Behavior Change

  NCT04043650

  Condition:   Physical Activity
  Intervention:   Behavioral: HeartSteps
  Sponsors:   University of Southern California;   University of California, San Diego;   Arizona State University;   Kaiser Permanente;   Northeastern University;   University of Massachusetts, Amherst
  Recruiting
• SMS Education for Post-operative Pain

  NCT04039191

  Conditions:   Opioid Use;   Pain, Postoperative
  Interventions:   Behavioral: SMS education;   Behavioral: SMS survey
  Sponsor:   Cedars-Sinai Medical Center
  Recruiting
• TMS and Exposure Therapy

  NCT04019054

  Conditions:   Arachnophobia;   Phobia
  Interventions:   Device: Intermittent Theta Burst Stimulation (iTBS), Ventromedial Prefrontal Cortex (vmPFC);   Device: Intermittent Theta Burst Stimulation (iTBS), vertex
  Sponsor:   University of California, Los Angeles
  Recruiting
• Modified Immune Cells (CD19/CD20 CAR-T Cells) in Treating Patients With Recurrent or Refractory B-Cell Lymphoma or Chronic Lymphocytic Leukemia

  NCT04007029

  Conditions:   CD19 Positive;   CD20 Positive;   Recurrent Chronic Lymphocytic Leukemia;   Recurrent Diffuse Large B-Cell Lymphoma;   Recurrent Follicular Lymphoma;   Recurrent Mantle Cell Lymphoma;   Recurrent Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma;   Recurrent Small Lymphocytic Lymphoma;   Refractory Chronic Lymphocytic Leukemia;   Refractory Diffuse Large B-Cell Lymphoma;   Refractory Follicular Lymphoma;   Refractory Mantle Cell Lymphoma;   Refractory Primary Mediastinal (Thymic) Large B-Cell Cell Lymphoma;   Refractory Small Lymphocytic Lymphoma
  Interventions:   Biological: Chimeric Antigen Receptor T-Cell Therapy;   Drug: Cyclophosphamide;   Drug: Fludarabine Phosphate;   Biological: Tocilizumab
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI);   Parker Institute for Cancer Immunotherapy
  Recruiting
• Virtual Reality in SOD

  NCT03999333

  Condition:   Sphincter of Oddi Dysfunction
  Intervention:   Device: Virtual Reality (Oculus Go)
  Sponsor:   Cedars-Sinai Medical Center
  Recruiting
• SPECT/CT for the Characterization of Renal Masses

  NCT03996850

  Conditions:   Kidney Neoplasm;   Renal Mass
  Interventions:   Procedure: Computed Tomography;   Other: Questionnaire Administration;   Procedure: Single Photon Emission Computed Tomography;   Radiation: Technetium Tc-99m Sestamibi
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• Nivolumab in Combination With Chemotherapy Before Surgery in Treating Patients With Borderline Resectable Pancreatic Cancer

  NCT03970252

  Conditions:   Borderline Resectable Pancreatic Adenocarcinoma;   Resectable Pancreatic Ductal Adenocarcinoma
  Interventions:   Drug: Fluorouracil;   Drug: Irinotecan;   Drug: Irinotecan Hydrochloride;   Drug: Leucovorin;   Drug: Leucovorin Calcium;   Biological: Nivolumab;   Drug: Oxaliplatin;   Procedure: Therapeutic Conventional Surgery
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• Quadratus Lumborum Nerve Blocks for Myomectomies

  NCT03935815

  Conditions:   Laparoscopic Myomectomy;   Quadratus Lumborum Nerve Block
  Interventions:   Drug: Ropivacaine injection;   Procedure: Sham treatment
  Sponsor:   University of California, Los Angeles
  Recruiting
• The Getting Off App for Methamphetamine-Using Gay and Bisexual Men

  NCT03884946

  Conditions:   Methamphetamine Abuse;   HIV/AIDS
  Intervention:   Other: Getting Off App
  Sponsors:   Friends Research Institute, Inc.;   National Institute on Drug Abuse (NIDA)
  Recruiting
• Train Your Brain: Neurofeedback Intervention for PTSD

  NCT03858933

  Condition:   Stress Disorders, Post-Traumatic
  Intervention:   Device: eBrainFit Platform
  Sponsors:   University of Southern California;   Tel Aviv University
  Recruiting
• Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments

  NCT03844412

  Conditions:   Vestibulodynia;   Temporomandibular Disorder;   Fibromyalgia Syndrome;   Irritable Bowel Syndrome;   Migraines;   Tension Headache;   Endometriosis;   Interstitial Cystitis;   Back Pain;   Chronic Fatigue Syndrome
  Interventions:   Drug: 5% lidocaine/5 mg/ml 0.02% estradiol compound cream;   Drug: Nortriptyline;   Drug: Placebo cream;   Drug: Placebo pill
  Sponsors:   Duke University;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
  Recruiting
• WALNUTS for POWER: Polyphenols, Omega-3 Fatty Acids, Weight Loss, and EneRgy

  NCT03824652

  Condition:   Prostate Cancer
  Interventions:   Other: walnuts;   Other: usual diet;   Other: phone counseling with dietitian
  Sponsors:   Stephen Freedland;   California Walnut Commission
  Recruiting
• LOL: It's All Improv After Cancer!™

  NCT03824132

  Conditions:   Breast Cancer;   Psychological Distress
  Interventions:   Behavioral: Improvisational comedy classes;   Behavioral: Waitlist control
  Sponsors:   Arash Asher, MD;   Tower Cancer Research Foundation
  Recruiting
• Reactive vs. Proactive Pain Control in IBD

  NCT03798405

  Conditions:   Inflammatory Bowel Diseases;   Pain;   Opioid Use;   Crohn Disease;   Ulcerative Colitis
  Intervention:   Behavioral: Proactive Analgesic Inpatient Narcotic-Sparing
  Sponsor:   Cedars-Sinai Medical Center
  Recruiting
• Collection of Blood Samples From Patients With Relapsing MS Who Developed ITP After Receiving Lemtrada

  NCT03784898

  Condition:   Multiple Sclerosis
  Intervention:   Other: Blood draw for future biomarker analysis
  Sponsor:   Genzyme, a Sanofi Company
  Recruiting
• Ketogenic Diet in Non-alcoholic Fatty Liver Disease

  NCT03784716

  Conditions:   Fatty Liver, Nonalcoholic;   Liver Diseases
  Interventions:   Other: Ketogenic Diet;   Other: Standard Weight Loss Diet
  Sponsor:   Shehnaz Hussain
  Recruiting
• Key Dimensions of PTSD and ED

  NCT03778307

  Conditions:   Trauma;   PTSD;   Endothelial Dysfunction
  Interventions:   Behavioral: Psychophysiological fear conditioning and extinction task;   Behavioral: Eyetracking task
  Sponsors:   University of California, Los Angeles;   National Heart, Lung, and Blood Institute (NHLBI)
  Recruiting
• Adrenergic Blockers for Cardiac Changes in Early Parkinson's Disease

  NCT03775096

  Conditions:   REM Sleep Behavior Disorder;   Pre-motor Parkinson Disease;   Symptomatic Parkinson Disease
  Intervention:   Drug: Carvedilol
  Sponsor:   Michele Tagliati, MD
  Recruiting
• Multicenter Study of Seliciclib (R-roscovitine) for Cushing Disease

  NCT03774446

  Condition:   Cushing Disease
  Intervention:   Drug: Seliciclib
  Sponsor:   Cedars-Sinai Medical Center
  Recruiting
• Efficacy and Safety of SYN-010 in IBS-C

  NCT03763175

  Condition:   Irritable Bowel Syndrome With Constipation
  Interventions:   Drug: SYN-010 21 mg;   Drug: SYN-010 42 mg;   Drug: Placebo
  Sponsors:   Cedars-Sinai Medical Center;   Synthetic Biologics Inc.
  Recruiting
• Neoadjuvant Her2-targeted Therapy and Immunotherapy With Pembrolizumab

  NCT03747120

  Conditions:   HER2-positive Breast Cancer;   Breast Cancer
  Interventions:   Drug: Paclitaxel;   Drug: Trastuzumab;   Drug: Pertuzumab;   Drug: Pembrolizumab
  Sponsors:   Cedars-Sinai Medical Center;   Merck Sharp & Dohme Corp.
  Recruiting
• Prospective Randomized Controlled Trial of an Enhanced Recovery Protocol for Anorectal Surgery

  NCT03738904

  Condition:   Anorectal Disorder
  Interventions:   Combination Product: ERAS;   Combination Product: Standard of care
  Sponsor:   Cedars-Sinai Medical Center
  Recruiting
• SEACOAST 1- SEdAtion With COllAteral Support in Endovascular Therapy for Acute Ischemic Stroke

  NCT03737786

  Condition:   Acute Stroke
  Intervention:   Other: Tight control of end-tidal CO2 levels
  Sponsors:   University of California, Los Angeles;   University of Southern California
  Recruiting
• Social Engagement Strategies to Improve Medication Adherence

  NCT03734887

  Conditions:   Diabetes;   Atherosclerosis Cardiovascular Disease;   Congestive Heart Failure;   Poor Medication Adherence
  Interventions:   Behavioral: Social Network Feedback;   Behavioral: Private Feedback
  Sponsor:   University of California, Los Angeles
  Recruiting
• PK/PD of Vitamin D3 in Adults With CF

  NCT03734744

  Conditions:   Vitamin D Deficiency;   Cystic Fibrosis
  Intervention:   Dietary Supplement: Vitamin D3
  Sponsor:   University of Southern California
  Recruiting
• 18F-FDG PET and Osimertinib in Evaluating Glucose Utilization in Patients With EGFR Activated Recurrent Glioblastoma

  NCT03732352

  Conditions:   EGFR Gene Amplification;   EGFR Gene Mutation;   Glioblastoma;   Recurrent Glioblastoma;   Supratentorial Glioblastoma;   TP53 wt Allele
  Interventions:   Other: Fludeoxyglucose F-18;   Drug: Osimertinib;   Procedure: Positron Emission Tomography
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI);   Translational Research in Oncology;   AstraZeneca
  Recruiting
• Using Behavioral Science to Reduce Inappropriate Antibiotic Use in Acute Care Settings

  NCT03711292

  Conditions:   Antimicrobial Stewardship;   Acute Bronchitis;   Upper Respiratory Infection
  Intervention:   Behavioral: Antibiotic Stewardship
  Sponsors:   Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center;   Los Angeles County Department of Public Health;   University of California, Los Angeles
  Recruiting
• Study of Combined Kidney and Blood Stem Cell Transplant From a Brother or Sister Donor

  NCT03707262

  Conditions:   Renal Transplant Rejection;   Tolerance;   Kidney Transplant
  Intervention:   Biological: Donor CD34+ and CD3+ cells
  Sponsors:   Jeffrey Veale, MD;   OneLegacy Foundation
  Recruiting
• The Safety and Intake Rate of a Natural Compound Arctigenin in Healthy Men

  NCT03703388

  Condition:   Healthy
  Intervention:   Dietary Supplement: Arctigenin
  Sponsors:   University of California, Los Angeles;   Charles Drew University of Medicine and Science
  Recruiting
• The IBD&me Randomized Controlled Trial

  NCT03695783

  Condition:   Inflammatory Bowel Diseases
  Interventions:   Other: Online decision aid called IBD&me;   Other: Standardized educational material
  Sponsor:   Cedars-Sinai Medical Center
  Recruiting
• Talazoparib and Low-Dose Temozolomide in Treating Participants With Relapsed or Refractory Extensive-Stage Small Cell Lung Cancer

  NCT03672773

  Conditions:   Recurrent Extensive Stage Small Cell Lung Carcinoma;   Refractory Extensive Stage Small Cell Lung Carcinoma
  Interventions:   Drug: Talazoparib;   Drug: Temozolomide
  Sponsors:   Jonsson Comprehensive Cancer Center;   Translational Research in Oncology;   National Cancer Institute (NCI)
  Recruiting
• Stereotactic Body Radiation Therapy and Durvalumab With or Without Tremelimumab Before Surgery in Treating Participants With Human Papillomavirus Positive Oropharyngeal Squamous Cell Caner

  NCT03618134

  Conditions:   Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC (American Joint Committee on Cancer) v8;   Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8;   Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8;   Human Papillomavirus Positive;   Oropharyngeal Squamous Cell Carcinoma;   p16 Positive Neoplastic Cells Present;   Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8;   Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8;   Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
  Interventions:   Biological: Durvalumab;   Procedure: Modified Radical Neck Dissection;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration;   Radiation: Stereotactic Body Radiation Therapy;   Procedure: Transoral Robotic Surgery;   Biological: Tremelimumab
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• DHA Brain Delivery Trial

  NCT03613844

  Condition:   Brain DHA Delivery and Alzheimer's Disease Risk
  Interventions:   Drug: DHA;   Drug: Placebo
  Sponsors:   University of Southern California;   Huntington Medical Research Institutes;   National Institute on Aging (NIA);   Alzheimer’s Drug Discovery Foundation
  Recruiting
• Invasive Approach to Model Human Cortex-Basal Ganglia Action-Regulating Networks

  NCT03608228

  Condition:   Parkinson's Disease Patients Undergoing Deep Brain Stimulation (DBS) Surgery
  Intervention:   Other: Measuring electrical signals from the brain
  Sponsors:   University of California, Los Angeles;   The Cleveland Clinic;   University of California, San Francisco;   University of California, San Diego;   California Institute of Technology;   Cedars-Sinai Medical Center
  Recruiting
• Ibudilast for the Treatment of Alcohol Use Disorder

  NCT03594435

  Condition:   Alcohol Use Disorder
  Interventions:   Drug: Ibudilast;   Drug: Placebo oral capsule
  Sponsors:   University of California, Los Angeles;   National Institute on Alcohol Abuse and Alcoholism (NIAAA);   MediciNova
  Recruiting
• Trial of 68Ga-PSMA-11 PET/CT Molecular Imaging for Prostate Cancer Salvage Radiotherapy Planning [PSMA-SRT]

  NCT03582774

  Condition:   Recurrent Prostate Carcinoma
  Intervention:   Drug: 68Ga-PSMA-11
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• Transcranial Direct Current Stimulation as a Neuroprotection in Acute Stroke

  NCT03574038

  Condition:   Stroke, Acute
  Interventions:   Device: Transcranial Direct Current Stimulation;   Other: Sham Stimulation
  Sponsor:   University of California, Los Angeles
  Recruiting
• Nutritional Preferences and Product Accessibility in Oral Nutritional Supplements in Participants With Breast, Colorectal, Upper Gastrointestinal, or Prostate Cancer

  NCT03563352

  Conditions:   Breast Carcinoma;   Cholangiocarcinoma;   Colorectal Carcinoma;   Gastric Carcinoma;   Malignant Digestive System Neoplasm;   Pancreatic Carcinoma;   Prostate Carcinoma
  Interventions:   Other: Interview;   Other: Survey Administration
  Sponsors:   University of Southern California;   National Cancer Institute (NCI)
  Recruiting
• A Trial to Evaluate the Safety, Efficacy, and Tolerability of Brexpiprazole in Treating Agitation Associated With Dementia of the Alzheimer's Type

  NCT03548584

  Conditions:   Agitaton Associated With Alzheimer's Dementia;   Alzheimer Dementia
  Interventions:   Drug: Brexpiprazole;   Other: Placebo
  Sponsors:   Otsuka Pharmaceutical Development & Commercialization, Inc.;   H. Lundbeck A/S
  Recruiting
• Peri-Operative Ipilimumab+Nivolumab and Cryoablation Versus Standard Care in Women With Triple-negative Breast Cancer

  NCT03546686

  Condition:   Breast Cancer
  Interventions:   Drug: Ipilimumab;   Drug: Nivolumab;   Procedure: Core Biopsy/Cryoablation;   Procedure: Breast Surgery
  Sponsors:   Cedars-Sinai Medical Center;   Memorial Sloan Kettering Cancer Center
  Recruiting
• Intratumoral Administration of CCL21-gene Modified Dendritic Cell With Intravenous Pembrolizumab for Advanced NSCLC

  NCT03546361

  Condition:   Carcinoma, Non-Small-Cell Lung
  Interventions:   Genetic: Ad-CCL21-DC 1 x 07;   Genetic: Ad-CCL21-DC 3 x 07;   Genetic: Ad-CCL21-DC .05 x 07;   Drug: Pembrolizumab;   Genetic: Ad-CCL21-DC ExD
  Sponsors:   Jonsson Comprehensive Cancer Center;   California Institute for Regenerative Medicine (CIRM);   Merck Sharp & Dohme Corp.;   National Cancer Institute (NCI)
  Recruiting
• Stereotactic Body Radiation Therapy in Treating Patients With Localized Prostate Cancer That Have Undergone Surgery

  NCT03541850

  Conditions:   PSA Level Greater Than 0.03;   PSA Progression;   Stage I Prostate Adenocarcinoma AJCC (American Joint Committee on Cancer ) v7;   Stage II Prostate Adenocarcinoma AJCC v7;   Stage III Prostate Adenocarcinoma AJCC v7
  Interventions:   Drug: Antiandrogen Therapy;   Other: Quality-of-Life Assessment;   Radiation: Stereotactic Body Radiation Therapy
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• A Trial to Evaluate the Efficacy, Safety & Tolerability of Brexpiprazole in the Maintenance Treatment of Adults With Major Depressive Disorder

  NCT03538691

  Condition:   Major Depressive Disorder
  Interventions:   Drug: Brexpiprazole;   Drug: Placebo;   Drug: Citalopram Hydrobromide;   Drug: Escitalopram;   Drug: Fluoxetine;   Drug: Paroxetine;   Drug: Sertraline;   Drug: Duloxetine;   Drug: Venlafaxine Extended Release Oral Capsule
  Sponsor:   Otsuka Pharmaceutical Development & Commercialization, Inc.
  Recruiting
• Mindfulness Meditation and Insomnia in Alzheimer Disease Caregivers

  NCT03538574

  Condition:   Insomnia Chronic
  Interventions:   Behavioral: CBT-I;   Behavioral: MAP-I
  Sponsor:   University of California, Los Angeles
  Recruiting
• Hiatal Interrogation in Sleeve Gastrectomy

  NCT03527810

  Condition:   Sleeve Gastrectomy
  Interventions:   Procedure: Sleeve Gastrectomy Without Interrogation of Hiatus;   Procedure: Sleeve Gastrectomy With Interrogation of Hiatus
  Sponsors:   Miguel Burch;   Cedars-Sinai Medical Center
  Recruiting
• Haploidentical Stem Cell Transplant With Prophylactic Natural Killer DLI for Lymphoma, Multiple Myeloma, and CLL

  NCT03524235

  Conditions:   Multiple Myeloma;   CLL;   Chronic Lymphocytic Leukemia;   Lymphoma;   Hodgkin Lymphoma
  Interventions:   Radiation: Total Body Irradiation;   Procedure: Haploidentical Stem Cell Transplantation;   Biological: CD56-Enriched Donor Lymphocyte Infusion;   Drug: Bendamustine;   Drug: Fludarabine;   Drug: Rituximab
  Sponsors:   Noah Merin;   Miltenyi Biotec GmbH;   Teva Pharmaceutical Industries
  Recruiting
• Reducing Risk for Alzheimer's Disease in High-Risk Women Through Yogic Meditation Training

  NCT03503669

  Conditions:   Mild Cognitive Impairment;   Alzheimer's Disease
  Interventions:   Behavioral: Memory Training;   Behavioral: Kundalini yoga and meditation
  Sponsors:   University of California, Los Angeles;   Alzheimer's Research and Prevention Foundation
  Recruiting
• Rifaximin on Visceral Hypersensitivity

  NCT03462966

  Conditions:   Visceral Hypersensitivity;   Irritable Bowel Syndrome
  Intervention:   Drug: Rifaximin
  Sponsors:   Cedars-Sinai Medical Center;   Bausch Health Americas, Inc.
  Recruiting
• SMART Program in Irritable Bowel Syndrome (IBS)

  NCT03454386

  Condition:   Irritable Bowel Syndrome
  Interventions:   Behavioral: Stress Management and Resilience Training Program;   Behavioral: Self-Management Stress Reduction Program
  Sponsor:   University of California, Los Angeles
  Recruiting
• Treatment for Comorbid Social Anxiety and Alcohol Use Disorders.

  NCT03428490

  Conditions:   Alcohol Use Disorder;   Social Anxiety Disorder
  Interventions:   Behavioral: Fully integrated treatment;   Behavioral: Stand-alone Intensive Outpatient Program
  Sponsors:   University of California, Los Angeles;   National Institute on Alcohol Abuse and Alcoholism (NIAAA);   Matrix Institute on Addictions
  Recruiting
• Anti-SEMA4D Monoclonal Antibody VX15/2503 With Nivolumab or Ipilimumab in Treating Patients With Stage III or IV Melanoma

  NCT03425461

  Conditions:   Metastatic Melanoma;   Stage III Cutaneous Melanoma AJCC v7;   Stage IIIA Cutaneous Melanoma AJCC v7;   Stage IIIB Cutaneous Melanoma AJCC v7;   Stage IIIC Cutaneous Melanoma AJCC v7;   Stage IV Cutaneous Melanoma AJCC v6 and v7
  Interventions:   Biological: Anti-SEMA4D Monoclonal Antibody VX15/2503;   Biological: Ipilimumab;   Other: Laboratory Biomarker Analysis;   Biological: Nivolumab;   Other: Pharmacological Study
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• SCOUT Reflector for Tagging Lymph Nodes for Targeted Removal in Patients With Breast Cancer

  NCT03411070

  Conditions:   Positive Axillary Lymph Node;   Stage 0 Breast Cancer AJCC v6 and v7;   Stage I Breast Cancer AJCC v7;   Stage IA Breast Cancer AJCC v7;   Stage IB Breast Cancer AJCC v7;   Stage II Breast Cancer AJCC v6 and v7;   Stage IIA Breast Cancer AJCC v6 and v7;   Stage IIB Breast Cancer AJCC v6 and v7;   Stage III Breast Cancer AJCC v7;   Stage IIIA Breast Cancer AJCC v7;   Stage IIIB Breast Cancer AJCC v7;   Stage IIIC Breast Cancer AJCC v7
  Interventions:   Device: Implanted Medical Device;   Procedure: Therapeutic Conventional Surgery
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• Nanodiamond-Gutta Percha Composite Biomaterials for Root Canal Therapy

  NCT03376984

  Conditions:   Dental Pulp Diseases;   Dental Pulp Necrosis;   Nerve Root Pain Nec
  Interventions:   Combination Product: ND and AMOX modified Gutta Percha;   Device: Gutta Percha
  Sponsor:   University of California, Los Angeles
  Recruiting
• Breast Cancer Study of Preoperative Pembrolizumab + Radiation

  NCT03366844

  Condition:   Breast Cancer
  Interventions:   Drug: Pembrolizumab;   Radiation: RT Boost
  Sponsor:   Stephen Shiao
  Recruiting
• Spatial Frequency Domain Imaging (SFD) for Assessment of Diabetic Foot Ulcer Development and Healing

  NCT03341559

  Condition:   Diabetic Foot Ulcer
  Intervention:   Device: Spatial Frequency Domain Imaging (SFDI)
  Sponsors:   University of Southern California;   Modulated Imaging Inc.
  Recruiting
• Sleep and Healthy Aging Research for Depression (SHARE-D) Study

  NCT03256760

  Condition:   Depression in Old Age
  Interventions:   Biological: Endotoxin;   Biological: Placebo
  Sponsor:   Michael Irwin, MD
  Recruiting
• Target Engagement and Response to Oxytocin

  NCT03245437

  Condition:   Schizophrenia
  Interventions:   Drug: Oxytocin nasal spray;   Behavioral: Social Cognition Skills Training;   Behavioral: Health Management;   Drug: Placebo nasal spray
  Sponsor:   University of California, Los Angeles
  Recruiting
• Transcutaneous Electrical Acupoint Stimulation (TEAS) for Chronic Constipation

  NCT03243955

  Condition:   Constipation - Functional
  Interventions:   Device: Verum TEAS;   Device: Sham TEAS
  Sponsor:   University of California, Los Angeles
  Recruiting
• Intra-articular Adipose Tissue Injections for Osteoarthritis

  NCT03242707

  Condition:   Osteoarthritis, Knee
  Interventions:   Biological: Autologous adipose tissue injection;   Drug: Hyaluronic Acid
  Sponsor:   University of Southern California
  Recruiting
• Pravastatin Intervention to Delay Hepatocellular Carcinoma Recurrence

  NCT03219372

  Conditions:   Hepatocellular Carcinoma;   Liver Cirrhoses
  Interventions:   Drug: Pravastatin Pill;   Drug: Placebo Oral Tablet
  Sponsors:   Cedars-Sinai Medical Center;   National Institutes of Health (NIH);   National Cancer Institute (NCI)
  Recruiting
• Collection of Immunology Specimens From Patients With Cancer or Blood Disorders, and Healthy Volunteers

  NCT03207854

  Conditions:   Healthy Subject;   Hematologic and Lymphocytic Disorder;   Hematopoietic and Lymphoid Cell Neoplasm;   Immune System Disorder;   Malignant Neoplasm
  Interventions:   Procedure: Biospecimen Collection;   Other: Laboratory Biomarker Analysis;   Other: Questionnaire Administration
  Sponsors:   University of Southern California;   National Cancer Institute (NCI)
  Recruiting
• Preoperative Alpha Blockade for Pheochromocytoma

  NCT03176693

  Conditions:   Pheochromocytoma;   Paraganglioma
  Interventions:   Drug: Phenoxybenzamine;   Drug: Doxazosin
  Sponsor:   University of California, Los Angeles
  Recruiting
• Dose Escalation Trial of Neoadjuvant Radiosurgery for the Treatment of Metastatic Brain Tumors

  NCT03163368

  Condition:   Brain Metastases
  Interventions:   Radiation: Neoadjuvant stereotactic radiosurgery;   Procedure: Neurosurgical resection
  Sponsor:   Cedars-Sinai Medical Center
  Recruiting
• Personalized Cancer Care at Cedars-Sinai Medical Center Samuel Oschin Comprehensive Cancer Institute

  NCT03098576

  Condition:   Cancer
  Interventions:   Other: Matched targeted drug treatment;   Other: Unmatched standard of care
  Sponsor:   Cedars-Sinai Medical Center
  Recruiting
• QSM and Regional DCE MRI Permeability Using GOCART Technique

  NCT03091803

  Condition:   Intracranial Neoplasm
  Interventions:   Device: Dynamic Contrast-Enhanced Magnetic Resonance Imaging;   Drug: Gadobenate Dimeglumine;   Drug: Gadoterate Meglumine;   Device: Magnetic Resonance Imaging
  Sponsors:   University of Southern California;   National Cancer Institute (NCI)
  Recruiting
• Oxandrolone Rotator Cuff Trial

  NCT03091075

  Condition:   Rotator Cuff Tear
  Interventions:   Drug: Oxandrolone Pill;   Drug: Placebo Oral Tablet
  Sponsor:   University of Southern California
  Recruiting
• Whole-Heart Myocardial Blood Flow Quantification Using MRI

  NCT03064295

  Conditions:   Coronary Artery Disease;   Coronary Microvascular Disease
  Interventions:   Device: Myocardial Perfusion Cardiac MRI.;   Drug: Contrast;   Drug: Pharmacologic Stress Agent
  Sponsors:   Cedars-Sinai Medical Center;   National Heart, Lung, and Blood Institute (NHLBI)
  Recruiting
• My Nutritional Health App Testing

  NCT03052452

  Condition:   Gastrointestinal Irritation
  Intervention:   Other: My Nutritional Health App
  Sponsors:   Cedars-Sinai Medical Center;   University of Michigan;   Nestlé
  Recruiting
• Exercise and Diet Intervention in Promoting Weight Loss in Obese Patients With Stage I Endometrial Cancer

  NCT03042897

  Conditions:   Estrogen Receptor Positive;   Obesity;   Progesterone Receptor Positive;   Stage I Uterine Corpus Cancer;   Stage IA Uterine Corpus Cancer;   Stage IB Uterine Corpus Cancer
  Interventions:   Dietary Supplement: Dietary Intervention;   Behavioral: Exercise Intervention;   Other: Laboratory Biomarker Analysis;   Other: Quality-of-Life Assessment
  Sponsors:   University of Southern California;   National Cancer Institute (NCI)
  Recruiting
• Whole-Neck Computed Tomography Perfusion Scan in Imaging Patients With Head and Neck Tumors

  NCT02960308

  Conditions:   Head and Neck Neoplasm;   Malignant Head and Neck Neoplasm
  Intervention:   Radiation: Computed Tomography Perfusion Imaging
  Sponsors:   University of Southern California;   National Cancer Institute (NCI)
  Recruiting
• Gut Microbiome in Fecal Samples From Patients With Metastatic Cancer Undergoing Chemotherapy or Immunotherapy

  NCT02960282

  Conditions:   Metastatic Carcinoma;   Stage IV Colorectal Cancer;   Stage IVA Colorectal Cancer;   Stage IVB Colorectal Cancer
  Interventions:   Procedure: Biospecimen Collection;   Other: Laboratory Biomarker Analysis
  Sponsors:   University of Southern California;   National Cancer Institute (NCI)
  Recruiting
• Genetic, Metabolic, and Growth Factor Repository for Cerebrovascular Disorders

  NCT02910180

  Conditions:   Cerebrovascular Diseases;   Ischemic Stroke;   Repository
  Intervention:  
  Sponsor:   Cedars-Sinai Medical Center
  Recruiting
• Ultrasound Assessment of Rheumatoid Arthritis Patients Who Changed Diet

  NCT02881307

  Conditions:   Rheumatoid Arthritis;   Overweight
  Interventions:   Dietary Supplement: Whey Protein&Prebiotic Supplement;   Behavioral: Dietary Counseling;   Behavioral: Dietary recommendations
  Sponsor:   Dr. Veena Ranganath
  Recruiting
• Prospective Study Comparing Brand and Generic Immunosuppression on Transplant Outcomes, Adherence, & Immune Response in Kidney Transplant Recipients

  NCT02866682

  Condition:   Renal Transplant Rejection
  Interventions:   Drug: Prograf;   Drug: Tacrolimus
  Sponsors:   University of California, Los Angeles;   Food and Drug Administration (FDA)
  Recruiting
• Novel Lung Imaging in Adults Undergoing Radiation Therapy to Assess for Radiation Pneumonitis

  NCT02735746

  Conditions:   Lung Cancer;   Breast Cancer;   Mediastinum Lesion;   Radiation Pneumonitis
  Interventions:   Radiation: 4D Computed Tomography (CT);   Radiation: Cone Beam CT;   Radiation: Low-dose Cinefluorography;   Device: Pulmonary Function Tests
  Sponsor:   Cedars-Sinai Medical Center
  Recruiting
• Lifestyle Enriching Activities for Research in Neuroscience Intervention Trial: LEARNit Study

  NCT02726906

  Conditions:   Aging;   Cognitive Ability, General
  Interventions:   Behavioral: Moderate-aerobic walking;   Radiation: Positron Emission Tomography (PET) scan;   Behavioral: Healthy living education;   Device: Physical activity monitor
  Sponsor:   University of Southern California
  Recruiting
• Phase II Study of 5-Day Hypofractionated Preoperative Radiation Therapy for Soft Tissue Sarcomas: Expansion Cohort

  NCT02701153

  Condition:   Recurrent Adult Soft Tissue Sarcoma
  Interventions:   Procedure: Conventional Surgery;   Radiation: Hypofractionated Radiation Therapy;   Other: Laboratory Biomarker Analysis;   Other: Questionnaire Administration
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• Nanodiamond Modified Gutta Percha (NDGP) Composite for Non-surgical Root Canal Therapy (RCT) Filler Material

  NCT02698163

  Conditions:   Dental Pulp Diseases;   Dental Pulp Necrosis;   Nerve Root Pain Nec
  Interventions:   Device: Nanodiamond reinforced Gutta Percha;   Device: Gutta Percha
  Sponsor:   University of California, Los Angeles
  Recruiting
• Nutrition Support to Improve Outcomes in Patients With Unresectable Pancreatic Cancer

  NCT02681601

  Condition:   Cancer of Pancreas
  Interventions:   Dietary Supplement: Nutrawell Powder;   Other: Diet Only;   Dietary Supplement: OmegaRich fish oil supplement
  Sponsor:   Jonsson Comprehensive Cancer Center
  Recruiting
• The Effect of Coffee Consumption in Enhancing Recovery of Bowel Function Following Colorectal Surgery.

  NCT02639728

  Condition:   Postoperative Ileus
  Interventions:   Other: Regular Coffee;   Other: Decaffeinated coffee;   Other: Warm water
  Sponsor:   Cedars-Sinai Medical Center
  Recruiting
• Active Surveillance of Papillary Thyroid Microcarcinoma

  NCT02609685

  Condition:   Papillary Thyroid Microcarcinoma
  Intervention:   Other: Active Surveillance
  Sponsor:   Cedars-Sinai Medical Center
  Recruiting
• Use of Acthar in Rheumatoid Arthritis (RA) Related Flares

  NCT02541955

  Condition:   Rheumatoid Arthritis (RA)
  Intervention:   Drug: Acthar
  Sponsor:   Dr. Veena Ranganath
  Recruiting
• Treatment of Cognitive and Negative Symptoms in Schizophrenia With N-acetylcysteine

  NCT02505477

  Conditions:   Schizophrenia;   Cognitive Deficits;   Schizophrenia; Negative Type
  Interventions:   Drug: N-acetylcysteine;   Other: Treatment as Usual
  Sponsor:   University of California, Los Angeles
  Recruiting
• High-Intensity Interval Training for Stage I-III Breast Cancer Patients

  NCT02454777

  Conditions:   Stage IA Breast Cancer;   Stage IB Breast Cancer;   Stage IIA Breast Cancer;   Stage IIB Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
  Interventions:   Behavioral: Exercise Intervention;   Other: Laboratory Biomarker Analysis;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration
  Sponsors:   University of Southern California;   National Cancer Institute (NCI)
  Recruiting
• FORE-SIGHT Tissue Oximeter During Cardiac Surgery

  NCT02426268

  Condition:   Cardiac Surgical Patients
  Intervention:  
  Sponsors:   University of California, Los Angeles;   CAS Medical Systems, Inc.
  Recruiting
• A Mobile and Virtual Reality Intervention for Adolescent Depression

  NCT04165681

  Condition:   Depression
  Intervention:   Other: Limbix Spark
  Sponsor:   Limbix Health, Inc.
  Recruiting
• Spinal Cord Neuromodulation for SCI

  NCT02313194

  Conditions:   Cervical Spinal Cord Injury;   Tetraparesis;   Tetraplegia
  Intervention:   Device: Epidural Stimulation
  Sponsor:   University of California, Los Angeles
  Recruiting
• Clinical Validation of the Role of microRNA Binding Site Mutations in Cancer Risk, Prevention and Treatment

  NCT02253251

  Condition:   Cancer
  Intervention:   Genetic: KRAS-variant and microRNA binding site mutation testing
  Sponsor:   MiraKind
  Recruiting
• Core Biopsies for Establishing a Breast Tumor Tissue Repository

  NCT02250352

  Condition:   Breast Cancer
  Intervention:   Other: cytology specimen collection procedure
  Sponsors:   University of Southern California;   National Cancer Institute (NCI)
  Recruiting
• Stem Cell Gene Therapy for Sickle Cell Disease

  NCT02247843

  Condition:   Sickle Cell Disease
  Intervention:   Biological: βAS3-FB vector transduced peripheral blood CD34+ cells
  Sponsors:   Donald B. Kohn, M.D.;   California Institute for Regenerative Medicine (CIRM)
  Recruiting
• Super HEROES: Searching How the Extract Rebaudioside Occludes Excess Steatosis

  NCT03985020

  Condition:   Non-Alcoholic Fatty Liver Disease
  Interventions:   Other: Stevia Intervention;   Other: Water Intervention
  Sponsor:   Children's Hospital Los Angeles
  Recruiting
• Low-Fat Diet and Fish Oil in Men on Active Surveillance for Prostate Cancer

  NCT02176902

  Conditions:   Adenocarcinoma of the Prostate;   Stage I Prostate Cancer;   Stage IIA Prostate Cancer;   Stage IIB Prostate Cancer
  Interventions:   Behavioral: behavioral dietary intervention;   Dietary Supplement: omega-3 fatty acid;   Other: laboratory biomarker analysis
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• 3D Multi-Contrast Atherosclerosis Characterization of the Carotid Artery

  NCT02163408

  Condition:   Carotid Artery Disease
  Intervention:   Other: MRI with/without contrast
  Sponsors:   Cedars-Sinai Medical Center;   National Heart, Lung, and Blood Institute (NHLBI);   American Heart Association
  Recruiting
• Empiric Treatment for Acute HIV in the ED

  NCT03711253

  Condition:   Acute HIV Infection
  Intervention:   Drug: Bictegravir 50mg+Tenofovir AF 25 mg+emtricitabine 200 mg
  Sponsor:   University of Southern California
  Recruiting
• Nurse-Led Community Health Worker Adherence Model in 3HP Delivery Among Homeless Adults at Risk for TB Infection and HIV

  NCT03702049

  Condition:   Latent Tuberculosis Infection
  Intervention:   Behavioral: Nurse-led Community Health Worker TBI (RN/CHW TBI) program
  Sponsors:   University of California, Irvine;   University of California, Los Angeles
  Recruiting
• Deep Brain Stimulation of the Amygdala for Combat Post-Traumatic Stress Disorder

  NCT02091843

  Condition:   Posttraumatic Stress Disorder
  Interventions:   Procedure: DBS of the Basolateral Nucleus of the Amygdala;   Device: Medtronic Activa PC DBS of the Basolateral Nucleus of the Amygdala
  Sponsor:   VA Greater Los Angeles Healthcare System
  Recruiting
• Adolescent Cancer Telemedicine for Pain Management

  NCT03603886

  Condition:   Cancer
  Interventions:   Behavioral: Telemedicine Pain Management Intervention (immediate group);   Behavioral: Telemedicine Pain Management Intervention (waitlist group, intervention administered following 4-week waitlist period)
  Sponsors:   University of California, Los Angeles;   Rally Foundation for Childhood Cancer Research;   Bear Necessities Pediatric Cancer Foundation
  Recruiting
• At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

  NCT01931644

  Conditions:   All Diagnosed Health Conditions;   ADD/ADHD;   Alopecia Areata;   Ankylosing Spondylitis;   Asthma;   Atopic Dermatitis Eczema;   Beta Thalassemia;   Bipolar Disorder;   Breast Cancer;   Celiac Disease;   Cervical Cancer;   Chronic Inflammatory Demyelinating Polyneuropathy;   Chronic Kidney Diseases;   Chronic Obstructive Pulmonary Disease;   Colon Cancer;   Colorectal Cancer;   Crohn's Disease;   Cystic Fibrosis;   Depression;   Diabetes Mellitus;   Duchenne Muscular Dystrophy;   Endometriosis;   Epilepsy;   Facioscapulohumeral Muscular Dystrophy;   G6PD Deficiency;   General Anxiety Disorder;   Hepatitis B;   Hereditary Hemorrhagic Telangiectasia;   HIV/AIDS;   Human Papilloma Virus;   Huntington's Disease;   Idiopathic Thrombocytopenic Purpura;   Insomnia;   Kidney Cancer;   Leukemia;   Lung Cancer;   Lupus Nephritis;   Lymphoma;   Melanoma;   Multiple Myeloma;   Multiple Sclerosis;   Myositis;   Myotonic Dystrophy;   Ovarian Cancer;   Pancreatic Cancer;   Parkinson's Disease;   Polycystic Kidney Diseases;   Prostate Cancer;   Psoriasis;   Psoriatic Arthritis;   Rosacea;   Scleroderma;   Sickle Cell Anemia;   Sickle Cell Trait;   Sjogren's Syndrome;   Skin Cancer;   Spinal Muscular Atrophy;   Systemic Lupus Erythematosus;   Thrombotic Thrombocytopenic Purpura;   Trisomy 21;   Ulcerative Colitis
  Intervention:  
  Sponsor:   Sanguine Biosciences
  Recruiting
• N-Acetyl Cysteine Protects Pulpal Stem Cells in Endodontic Revascularization

  NCT03451435

  Condition:   Endodontic Disease
  Intervention:   Drug: N acetyl cysteine
  Sponsor:   University of California, Los Angeles
  Recruiting
• Light-Scattering Spectroscopy for Detection of Breast Cancer

  NCT01755208

  Conditions:   Healthy, no Evidence of Disease;   Stage II Breast Cancer;   Stage IIIA Breast Cancer;   Stage IIIB Breast Cancer;   Stage IIIC Breast Cancer
  Intervention:   Procedure: light-scattering spectroscopy
  Sponsors:   University of Southern California;   National Cancer Institute (NCI)
  Recruiting
• Standard Endoscopic Hemostasis Versus OVESCO Severe Non-variceal UGI Hemorrhage

  NCT03065465

  Condition:   Upper Gastrointestinal Hemorrhage
  Interventions:   Device: Over-the-scope hemoclipping device;   Other: Standard endoscopic treatment
  Sponsors:   CURE Digestive Diseases Research Center;   University of California, Los Angeles;   VA Greater Los Angeles Healthcare System
  Recruiting
• Clinical Model in Evaluating Clinical, Psychosocial, and Health Economic Factors in Adolescent and Young Adult Patients With Cancer

  NCT03057639

  Condition:   Malignant Neoplasm
  Interventions:   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration
  Sponsors:   University of Southern California;   National Cancer Institute (NCI)
  Recruiting
• Laboratory-based Hypnosis Intervention on Pain Responsivity in Adolescents With Sickle Cell Disease

  NCT02987725

  Condition:   Sickle Cell Disease
  Interventions:   Behavioral: Hypnosis;   Behavioral: Attention Control
  Sponsors:   University of California, Los Angeles;   National Heart, Lung, and Blood Institute (NHLBI)
  Recruiting
• Acromegaly Combination Treatment Study

  NCT01538966

  Condition:   Acromegaly
  Interventions:   Drug: Pegvisomant;   Drug: Octreotide LAR;   Drug: Lanreotide
  Sponsor:   Cedars-Sinai Medical Center
  Recruiting
• Anxiety and Reward Interaction and Prediction of Outcomes in Anorexia Nervosa

  NCT02948452

  Conditions:   Anorexia Nervosa, Restricting Type;   Anxiety
  Intervention:   Other: fMRI
  Sponsor:   University of California, Los Angeles
  Recruiting
• Predicting Diabetic Retinopathy From Risk Factor Data and Digital Retinal Images

  NCT03694145

  Conditions:   Diabetic Retinopathy;   Diabetic Macular Edema
  Intervention:   Other: In-Person Eye Examination
  Sponsors:   Charles Drew University of Medicine and Science;   National Library of Medicine (NLM);   Los Angeles County Department of Public Health;   University of California, Los Angeles
  Recruiting
• Healing Our Hearts Minds and Bodies: CVD Reduction in Persons With HIV

  NCT04025463

  Conditions:   HIV/AIDS;   Cardiovascular Risk Factors;   Trauma, Psychological
  Intervention:   Behavioral: HHMB
  Sponsors:   University of California, Los Angeles;   National Heart, Lung, and Blood Institute (NHLBI)
  Recruiting
• A Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers

  NCT04025216

  Conditions:   Non-Small Cell Lung Cancer;   Ovarian Cancer;   Fallopian Tube Cancer;   Triple Negative Breast Cancer;   Multiple Myeloma;   Pancreatic Ductal Adenocarcinoma
  Interventions:   Biological: CART-TnMUC1;   Drug: Cyclophosphamide;   Drug: Fludarabine
  Sponsor:   Tmunity Therapeutics
  Recruiting
• Impact of Phone Call About Financial Reimbursement Program on Access to Cancer Clinical Trials

  NCT03943082

  Condition:   Malignant Neoplasm
  Interventions:   Behavioral: Cancer Educational Materials;   Other: Follow-Up Care;   Behavioral: Questionnaire
  Sponsors:   University of California, San Francisco;   Lazarex Cancer Foundation
  Recruiting
• Laparotomy Versus Percutaneous Endoscopic Correction of Myelomeningocele

  NCT03856034

  Conditions:   Neural Tube Defects;   Spina Bifida;   Myelomeningocele;   Chiari Malformation
  Intervention:   Device: Fetoscopy
  Sponsors:   USFetus;   Wellington Hospital;   University of Southern California
  Recruiting
• A Study of RX108 in Patients With Locally Advanced or Metastatic Solid Tumors

  NCT03646071

  Conditions:   Locally Advanced Solid Tumors;   Metastatic Solid Tumors
  Intervention:   Drug: RX108
  Sponsor:   NeuPharma, Inc.
  Recruiting
• A Nutrition-Focused QIP in Outpatient Clinics

  NCT03628196

  Condition:   Malnutrition
  Intervention:  
  Sponsors:   Abbott Nutrition;   University of Southern California
  Recruiting
• Therapeutic Vaccination in Treated HIV Disease

  NCT03606213

  Condition:   HIV-1-infection
  Interventions:   Biological: PENNVAX-GP;   Biological: INO-6145;   Biological: INO-9012;   Device: CELLECTRA® 2000
  Sponsors:   Steven Deeks;   National Institute of Allergy and Infectious Diseases (NIAID);   University of California, Los Angeles;   Inovio Pharmaceuticals
  Recruiting
• Study to Find a Safe and Effective Dose of SKI-G-801 in the Treatment of Patients With Acute Myeloid Leukemia (AML)

  NCT03564288

  Condition:   Acute Myeloid Leukemia
  Intervention:   Drug: SKI-G-801
  Sponsors:   Oscotec Inc.;   PPD
  Recruiting
• A Dyadic Sleep Intervention for Alzheimer's Disease Patients and Their Caregivers

  NCT03455569

  Conditions:   Sleep;   Alzheimer Disease
  Interventions:   Behavioral: Behavioral sleep education;   Behavioral: Education only
  Sponsor:   University of California, Los Angeles
  Recruiting
• Treatment for Affect Dimensions

  NCT03439748

  Conditions:   Anhedonia;   Depression;   Anxiety
  Interventions:   Behavioral: Positive Affect Treatment;   Behavioral: Negative Affect Treatment
  Sponsors:   University of California, Los Angeles;   Southern Methodist University
  Recruiting
• Deep Brain Stimulation (DBS) for Depression Using Directional Current Steering and Individualized Network Targeting

  NCT03437928

  Condition:   Major Depressive Disorder
  Intervention:   Device: Directional Deep Brain Stimulation
  Sponsors:   Baylor College of Medicine;   University of California, Los Angeles
  Recruiting
• Phase I Study of Combination of Gedatolisib With Palbociclib and Faslodex in Patients With ER+/HER2- Breast Cancer

  NCT02626507

  Condition:   Breast Cancer
  Interventions:   Drug: Gedatolisib;   Drug: Faslodex;   Drug: Palbociclib;   Drug: Zoladex
  Sponsor:   Hoffman Oncology
  Recruiting
• Gene Modified Immune Cells (IL13Ralpha2 CAR T Cells) After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma

  NCT04119024

  Conditions:   Clinical Stage IV Cutaneous Melanoma AJCC v8;   IL13RA2 Positive;   Metastatic Melanoma;   Cutaneous Melanoma, Stage III;   Cutaneous Melanoma, Stage IV
  Interventions:   Drug: Cyclophosphamide;   Drug: Fludarabine Phosphate;   Biological: IL13Ralpha2-specific Hinge-optimized 4-1BB-co-stimulatory CAR/Truncated CD19-expressing Autologous TN/MEM Cells;   Drug: Recombinant Interleukin-2
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• Onvansertib in Combination With FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer Patients With a Kras Mutation

  NCT03829410

  Conditions:   Metastatic Colorectal Cancer;   KRAS Gene Mutation
  Interventions:   Drug: Onvansertib;   Biological: Bevacizumab;   Drug: FOLFIRI
  Sponsor:   Trovagene, Inc.
  Recruiting
• Psychosocial Outcomes in Hand Therapy

  NCT03458013

  Condition:   Hand Injuries
  Intervention:   Behavioral: Mindfulness Meditation
  Sponsors:   University of Southern California;   Abbott Medical Devices;   California Foundation for Occupational Therapy
  Recruiting
• Engaging Seronegative Youth to Optimize HIV Prevention Continuum

  NCT03134833

  Conditions:   HIV;   Mental Health;   Substance Use;   STI
  Interventions:   Behavioral: Automated Messaging & Monitoring;   Behavioral: Peer Support;   Behavioral: Coaching
  Sponsors:   University of California, Los Angeles;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   Tulane University Health Sciences Center;   University of California, San Francisco;   Friends Research Institute, Inc.
  Recruiting
• Stepped Care for Youth Living With HIV

  NCT03109431

  Conditions:   HIV;   Mental Health;   Illicit Substance Use;   Sexually Transmitted Infections (STI)
  Interventions:   Behavioral: Level 1;   Behavioral: Level 2;   Behavioral: Level 3
  Sponsors:   University of California, Los Angeles;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD);   Wake Forest University Health Sciences;   Tulane University Health Sciences Center;   Columbia University
  Recruiting
• Nicotinamide as an Early Alzheimer's Disease Treatment

  NCT03061474

  Conditions:   Alzheimer's Disease;   Mild Cognitive Impairment
  Interventions:   Drug: Nicotinamide;   Drug: Placebo Comparator
  Sponsor:   University of California, Irvine
  Recruiting
• Combination Therapy With Pembrolizumab and sEphB4-HSA in Previously Treated Urothelial Carcinoma

  NCT02717156

  Condition:   Stage IV Bladder Urothelial Carcinoma
  Interventions:   Procedure: Computed Tomography;   Other: Laboratory Biomarker Analysis;   Biological: Pembrolizumab;   Procedure: Positron Emission Tomography;   Biological: Recombinant EphB4-HSA Fusion Protein
  Sponsors:   University of Southern California;   National Cancer Institute (NCI)
  Recruiting
• Multi-antigen CMV-Modified Vaccinia Ankara Vaccine in Treating Pediatric Patients With Positive Cytomegalovirus Undergoing Donor Stem Cell Transplant

  NCT03354728

  Conditions:   Cytomegalovirus Positive;   Hematopoietic Cell Transplant Recipient
  Interventions:   Biological: Multi-antigen CMV-Modified Vaccinia Ankara Vaccine;   Other: Laboratory Biomarker Analysis
  Sponsor:   City of Hope Medical Center
  Recruiting
• Cell-Free DNA and RNA in Blood fromMetastatic Prostate Cancer Patients

  NCT02853097

  Conditions:   Hormone-Resistant Prostate Cancer;   Metastatic Prostate Carcinoma;   Prostate Adenocarcinoma
  Interventions:   Other: Cytology Specimen Collection Procedure;   Other: Laboratory Biomarker Analysis
  Sponsors:   University of Southern California;   National Cancer Institute (NCI)
  Recruiting
• Pembrolizumab in Treating Participants With Leukoplakia

  NCT03603223

  Conditions:   Erythroleukoplakia;   Leukoplakia;   Verrucous Oral Leukoplakia
  Intervention:   Biological: Pembrolizumab
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI);   Merck Sharp & Dohme Corp.
  Recruiting
• Pevonedistat, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia

  NCT03330821

  Conditions:   Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome;   Acute Myeloid Leukemia With Myelodysplasia-Related Changes;   Therapy-Related Acute Myeloid Leukemia
  Interventions:   Drug: Cytarabine;   Drug: Idarubicin;   Other: Laboratory Biomarker Analysis;   Drug: Pevonedistat;   Other: Pharmacological Study
  Sponsors:   University of Southern California;   National Cancer Institute (NCI)
  Recruiting
• Prevention and Treatment Continuum for Youth at HIV Risk, Acutely Infected and With Established HIV Infection

  NCT03205696

  Condition:   Human Immunodeficiency Virus
  Intervention:   Drug: Antiretrovirals
  Sponsors:   University of California, Los Angeles;   Los Angeles LGBT Center;   Tulane University
  Recruiting
• Optimizing IV Gentamicin in JEB

  NCT04140786

  Condition:   Junctional Epidermolysis Bullosa
  Intervention:   Drug: Gentamicin Sulfate, Injectable
  Sponsor:   University of Southern California
  Recruiting
• Addressing Obesity in Early Care and Education Settings

  NCT04140032

  Condition:   Obesity
  Intervention:   Behavioral: Multi-level preschool obesity control intervention
  Sponsor:   University of California, Los Angeles
  Recruiting
• Music Appreciation After Cochlear Implantation

  NCT04099368

  Conditions:   Hearing Loss;   Cochlear Implants
  Intervention:   Behavioral: Musical pitch training
  Sponsors:   University of Southern California;   Ohio State University;   University of California, Merced
  Recruiting
• Team-Based Connected Health (TCH) to Improve Clinical Outcomes and Access in Atopic Dermatitis

  NCT03981926

  Conditions:   Atopic Dermatitis Eczema;   Atopic Dermatitis;   Eczema
  Intervention:   Other: Team-Based Connected Health (TCH)
  Sponsors:   University of Southern California;   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
  Recruiting
• N-Acetyl-L-Leucine for Ataxia-Telangiectasia (A-T)

  NCT03759678

  Conditions:   Ataxia Telangiectasia;   Louis Bar Syndrome
  Intervention:   Drug: IB1001
  Sponsor:   IntraBio Inc
  Recruiting
• 68Ga-PSMA-11 PET/CT in Imaging Patients With Intermediate or High Risk Prostate Cancer Before Surgery

  NCT03368547

  Conditions:   Prostate Adenocarcinoma;   Stage IIB Prostate Cancer AJCC v7;   Stage III Prostate Cancer AJCC v7;   Stage IV Prostate Cancer AJCC v7
  Interventions:   Procedure: Computed Tomography;   Radiation: Gallium Ga 68-labeled PSMA-11;   Other: Laboratory Biomarker Analysis;   Procedure: Positron Emission Tomography
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer

  NCT03240861

  Conditions:   HLA-A*0201 Positive Cells Present;   Locally Advanced Malignant Neoplasm;   NY-ESO-1 Positive;   Unresectable Malignant Neoplasm;   Sarcoma
  Interventions:   Other: 18F-FHBG;   Biological: Aldesleukin;   Drug: Busulfan;   Biological: Cellular Therapy;   Procedure: Computed Tomography;   Biological: Filgrastim;   Drug: Fludarabine;   Procedure: Leukapheresis;   Drug: Plerixafor;   Procedure: Positron Emission Tomography
  Sponsors:   Jonsson Comprehensive Cancer Center;   California Institute for Regenerative Medicine (CIRM);   National Cancer Institute (NCI)
  Recruiting
• Gallium Ga 68-labeled PSMA-11 PET/CT in Detecting Recurrent Prostate Cancer in Patients After Initial Therapy

  NCT02940262

  Conditions:   Prostate Adenocarcinoma;   PSA Progression;   Recurrent Prostate Carcinoma
  Interventions:   Radiation: Gallium Ga 68-labeled PSMA-11;   Other: Laboratory Biomarker Analysis;   Procedure: Positron Emission Tomography
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• Biologic Mesh in Preventing Hernia in Patients With Bladder Cancer Undergoing Radical Cystectomy With Ileal Conduit Diversion

  NCT02439060

  Conditions:   Bladder Carcinoma;   Hernia
  Intervention:   Other: Acellular Cadaveric Dermal Matrix
  Sponsors:   University of Southern California;   National Cancer Institute (NCI);   Musculoskeletal Transplant Foundation
  Recruiting
• Time Limited Trials to Reduce Non-Beneficial Intensive Care Unit Treatments

  NCT04181294

  Conditions:   Critical Illness;   Communication
  Interventions:   Behavioral: Family meetings using time limited trials as default ICU communication and care planning approach;   Behavioral: Usual practice
  Sponsors:   Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center;   Los Angeles Department of Health Services;   University of California, Los Angeles
  Recruiting
• sEphB4-HSA in Treating Patients With Metastatic Castration-Resistant Prostate Cancer

  NCT04033432

  Conditions:   Castration Levels of Testosterone;   Castration-Resistant Prostate Carcinoma;   Castration-Resistant Prostate Carcinoma Refractory to Second-Generation Androgen Receptor Axis-Targeted Agents;   Metastatic Prostate Adenocarcinoma;   Progressive Disease;   Prostate Carcinoma Metastatic in the Bone;   Prostate Carcinoma Metastatic in the Soft Tissue;   PSA Progression;   Stage IVB Prostate Cancer AJCC v8;   Testosterone Less Than 50 ng/dL
  Intervention:   Biological: Recombinant EphB4-HSA Fusion Protein
  Sponsors:   Northwestern University;   Vasgene Therapeutics, Inc;   National Cancer Institute (NCI)
  Recruiting
• Early Feasibility Study for the Foldax Tria Aortic Heart Valve

  NCT03851068

  Conditions:   Aortic Valve Disease;   Aortic Valve Stenosis
  Intervention:   Device: Foldax Tria Aortic Valve
  Sponsor:   Foldax, Inc
  Recruiting
• Pembrolizumab in Treating Participants With Recurrent Ovarian Cancer

  NCT03732950

  Conditions:   Recurrent Fallopian Tube Carcinoma;   Recurrent Ovarian Carcinoma;   Recurrent Primary Peritoneal Carcinoma
  Intervention:   Biological: Pembrolizumab
  Sponsors:   Jonsson Comprehensive Cancer Center;   National Cancer Institute (NCI)
  Recruiting
• Regorafenib and Pembrolizumab in Treating Participants With Advanced or Metastatic Colorectal Cancer

  NCT03657641

  Conditions:   Colorectal Cancer;   Colorectal Cancer Metastatic
  Interventions:   Biological: Pembrolizumab;   Drug: Regorafenib
  Sponsors:   University of Southern California;   National Cancer Institute (NCI)
  Recruiting
• Transplant of Redeemed Organs by Judicious Administration of New Direct-Acting Antivirals for Hepatitis-C Heart Recipients

  NCT03383419

  Condition:   Heart Failure
  Intervention:   Drug: Epclusa
  Sponsor:   Baylor Research Institute
  Recruiting
• Phase I Trial of Endoxifen Gel Versus Placebo in Women Undergoing Breast Surgery

  NCT03317405

  Conditions:   Ductal Breast Carcinoma In Situ;   Lobular Breast Carcinoma In Situ;   Stage 0 Breast Cancer AJCC v6 and v7;   Stage I Breast Cancer AJCC v7;   Stage IA Breast Cancer AJCC v7;   Stage IB Breast Cancer AJCC v7;   Stage II Breast Cancer AJCC v6 and v7;   Stage IIA Breast Cancer AJCC v6 and v7;   Stage IIB Breast Cancer AJCC v6 and v7;   Stage III Breast Cancer AJCC v7;   Stage IIIA Breast Cancer AJCC v7;   Stage IIIB Breast Cancer AJCC v7;   Stage IIIC Breast Cancer AJCC v7
  Interventions:   Other: Placebo Administration;   Other: Questionnaire Administration;   Drug: Z-Endoxifen Hydrochloride
  Sponsor:   National Cancer Institute (NCI)
  Recruiting
• Maraviroc to Augment Rehabilitation Outcomes After Stroke

  NCT03172026

  Condition:   Stroke
  Interventions:   Drug: Maraviroc 300 mg;   Behavioral: Rehabilitation therapy;   Drug: Placebo 300 mg
  Sponsors:   University of California, Los Angeles;   Burke Neurological Research Institute;   Yale University
  Recruiting
• Docetaxel and Carboplatin for Patients With mCRPC and DNA-Repair Deficiencies

  NCT02985021

  Conditions:   Hormone-Resistant Prostate Cancer;   Metastatic Prostate Carcinoma;   Recurrent Prostate Carcinoma;   Stage IV Prostate Cancer
  Interventions:   Drug: Carboplatin;   Drug: Docetaxel
  Sponsors:   Seattle Institute for Biomedical and Clinical Research;   Prostate Cancer Foundation;   VA Puget Sound Health Care System
  Recruiting
• Selective HDAC6 Inhibitor ACY 241 in Combination With Nivolumab in Patients With Unresectable Non Small Cell Lung Cancer

  NCT02635061

  Condition:   Non Small Cell Lung Cancer
  Interventions:   Drug: ACY-241;   Drug: Nivolumab
  Sponsor:   Celgene
  Recruiting
• Rizatriptan for Episodic Dizziness in Vestibular Migraine

  NCT02447991

  Conditions:   Vestibular Migraine;   Migrainous Vertigo
  Interventions:   Drug: Rizatriptan;   Drug: Placebo
  Sponsor:   Robert W. Baloh
  Recruiting
• Assess the Safety, Tolerability Oral PU-H71 in Subjects Taking Ruxolitinib

  NCT03935555

  Conditions:   Primary Myelofibrosis (PMF);   Post-Polycythemia Vera Myelofibrosis (Post-PV MF);   Post-Essential Thrombocythemia Myelofibrosis (Post-ET MF)
  Intervention:   Drug: PU-H71
  Sponsor:   Samus Therapeutics, Inc.
  Recruiting
• Study Evaluating GZ17-6.02 in Patients With Advanced Solid Tumors or Lymphoma

  NCT03775525

  Conditions:   Advanced Cancer;   Gastric Cancer;   Breast Cancer;   Pancreatic Cancer;   Prostate Cancer Metastatic;   Colo-rectal Cancer;   Solid Tumor;   Solid Carcinoma;   Solid Carcinoma of Stomach;   Cancer of Stomach;   Lymphoma;   Sarcoma;   Cutaneous T Cell Lymphoma;   Head and Neck Squamous Cell Carcinoma;   Basal Cell Carcinoma;   Cutaneous T-cell Lymphoma;   Cutaneous Squamous Cell Carcinoma
  Intervention:   Drug: GZ17-6.02
  Sponsors:   Genzada Pharmaceuticals USA, Inc.;   Translational Drug Development
  Recruiting
• The Promoting Resilience in Stress Management (PRISM) Intervention: a Multi-site Randomized Controlled Trial for Adolescents and Young Adults Receiving Hematopoietic Cell Transplantation

  NCT03640325

  Conditions:   Cancer;   Bone Marrow Neoplasms;   Anxiety;   Depression;   Quality of Life;   Adherence, Medication;   Coping Skills;   Adolescent Behavior
  Intervention:   Behavioral: PRISM (Promoting Resilience in Stress Management)
  Sponsors:   Seattle Children's Hospital;   Children's Hospital Los Angeles;   St. Jude Children's Research Hospital
  Recruiting
• Brain Implant for Neural Control of a Computer

  NCT01958086

  Condition:   Quadriplegia
  Intervention:   Device: Neural Communication System
  Sponsors:   Richard A. Andersen, PhD;   University of California, Los Angeles;   Casa Colina Hospital and Centers for Healthcare
  Recruiting
• Eculizumab to Treat Thrombotic Microangiopathy/Atypical Hemolytic Uremic Syndrome -Associated Multiple Organ Dysfunction Syndrome in Hematopoietic Stem Cell Transplant Recipients

  NCT03518203

  Conditions:   Thrombotic Microangiopathies;   Atypical Hemolytic Uremic Syndrome;   Multiple Organ Dysfunction Syndrome
  Intervention:   Drug: Eculizumab
  Sponsor:   Children's Hospital Medical Center, Cincinnati
  Recruiting
• Insulin-like Growth Factor 1 Receptor (IGF-1R) Antibody AMG479 (Ganitumab) in Combination With the Src Family Kinase (SFK) Inhibitor Dasatinib in People With Embryonal and Alveolar Rhabdomyosarcoma

  NCT03041701

  Conditions:   Rhabdomyosarcoma;   Rhabdomyosarcoma- Alveolar;   Rhabdomyosarcoma-Embryonal
  Interventions:   Drug: Dasatinib;   Drug: Ganitumab
  Sponsor:   National Cancer Institute (NCI)
  Recruiting
• Blood Flow Monitoring to Prevent Post-Polypectomy Induced Ulcer Bleeding

  NCT02875353

  Condition:   Delayed Post-Polypectomy Induced Ulcer Hemorrhage
  Intervention:   Device: Doppler Endoscopic Probe
  Sponsors:   VA Office of Research and Development;   University of California, Los Angeles;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
  Recruiting
• Humanized Monoclonal Antibody 3F8 (Hu3F8) With Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) in the Treatment of Recurrent Osteosarcoma

  NCT02502786

  Condition:   Recurrent Osteosarcoma
  Interventions:   Biological: humanized anti-GD2 antibody;   Drug: GM-CSF
  Sponsors:   Memorial Sloan Kettering Cancer Center;   Children's Hospital Los Angeles;   M.D. Anderson Cancer Center;   Y-mAbs Therapeutics
  Recruiting
• A Pediatric and Young Adult Trial of Genetically Modified T Cells Directed Against CD19 for Relapsed/Refractory CD19+ Leukemia

  NCT02028455

  Condition:   CD19+ Acute Leukemia
  Intervention:   Biological: Patient Derived CD19 specific CAR T cells also expressing an EGFRt
  Sponsor:   Seattle Children's Hospital
  Recruiting
• Providing Closed Loop Cortical Control of Extracorporeal Devices to Patients With Quadriplegia

  NCT01964261

  Condition:   Quadriplegia
  Intervention:   Device: Neural Prosthetic System 2 (NPS2)
  Sponsors:   Richard A. Andersen, PhD;   University of Southern California;   Rancho Los Amigos National Rehabilitation Center
  Recruiting
• Estriol Treatment in Multiple Sclerosis (MS): Effect on Cognition

  NCT01466114

  Conditions:   Relapsing-remitting Multiple Sclerosis;   Secondary-progressive Multiple Sclerosis;   Primary-progressive Multiple Sclerosis
  Interventions:   Drug: estriol;   Other: Placebo;   Drug: Norethindrone;   Other: Progestin Placebo
  Sponsor:   University of California, Los Angeles
  Recruiting
• Registry Study of Revcovi Treatment in Patients With ADA-SCID

  NCT03878069

  Conditions:   Adenosine Deaminase Deficiency;   Severe Combined Immunodeficiency
  Intervention:   Biological: elapegademase-lvlr
  Sponsor:   Leadiant Biosciences, Inc.
  Recruiting
• Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS)

  NCT03568669

  Conditions:   Congenital Central Hypoventilation Syndrome;   Congenital Central Hypoventilation;   CCHS;   CCHS With Hirschsprung Disease;   CCHS With Neural Crest Tumor;   CCHS With Neuroblastoma
  Intervention:   Other: NIH Toolbox Cognition Battery
  Sponsors:   Debra Weese-Mayer;   Ann & Robert H Lurie Children's Hospital of Chicago;   Seattle Children's Hospital;   Children's Hospital Los Angeles
  Recruiting
• Study to Evaluate the Safety and Efficacy of GS-6207 in Combination With Other Antiretroviral Agents in People Living With HIV

  NCT04143594

  Condition:   HIV-1-infection
  Interventions:   Drug: Oral GS-6207;   Drug: F/TAF;   Drug: Subcutaneous GS-6207;   Drug: TAF;   Drug: BIC;   Drug: B/F/TAF
  Sponsor:   Gilead Sciences
  Recruiting
• A Safety and Tolerability Study of INCAGN02390 in Select Advanced Malignancies

  NCT03652077

  Conditions:   Cervical Cancer;   Gastric Cancer;   Stomach Cancer;   Gastroesophageal Junction Cancer;   Esophageal Cancer;   Hepatocellular Carcinoma;   Melanoma;   Uveal Melanoma;   Merkel Cell Carcinoma;   Mesothelioma;   MSI;   Non-small Cell Lung Cancer;   NSCLC;   Ovarian Cancer;   Squamous Cell Carcinoma of the Head and Neck;   Small Cell Lung Cancer;   Renal Cell Carcinoma;   RCC;   Triple-negative Breast Cancer;   Urothelial Carcinoma;   Mismatch Repair Deficiency
  Intervention:   Drug: INCAGN02390
  Sponsor:   Incyte Corporation
  Recruiting
• A Safety and Tolerability Study of INCAGN02385 in Select Advanced Malignancies

  NCT03538028

  Conditions:   Cervical Cancer;   Microsatellite Instability (MSI)-High Endometrial Cancer;   Gastric Cancer (Including Stomach and Gastroesophageal Junction [GEJ]);   Esophageal Cancer;   Hepatocellular Carcinoma;   Melanoma (Uveal Melanoma Excluded);   Merkel Cell Carcinoma;   Mesothelioma;   MSI-high Colorectal Cancer;   Non-small Cell Lung Cancer (NSCLC);   Ovarian Cancer;   Squamous Cell Carcinoma of the Head and Neck (SCCHN);   Small Cell Lung Cancer (SCLC);   Renal Cell Carcinoma (RCC);   Triple-negative Breast Cancer;   Urothelial Carcinoma;   Diffuse Large B-cell Lymphoma
  Intervention:   Biological: INCAGN02385
  Sponsor:   Incyte Biosciences International Sàrl
  Recruiting
• Phase 1B Study Evaluating Alternative Routes of Administration of CMP-001 in Combination With Pembrolizumab in Participants With Advanced Melanoma

  NCT03084640

  Condition:   Malignant Melanoma
  Interventions:   Drug: CMP-001;   Drug: Pembrolizumab
  Sponsor:   Checkmate Pharmaceuticals
  Recruiting
• Trial of NanoPac® in Subjects With Locally Advanced Pancreatic Adenocarcinoma

  NCT03077685

  Condition:   Locally Advanced Pancreatic Adenocarcinoma
  Intervention:   Drug: NanoPac®
  Sponsors:   NanOlogy, LLC;   US Biotest, Inc.
  Recruiting
• Cochlear Implantation in Adults With Asymmetric Hearing Loss Clinical Trial

  NCT03052920

  Condition:   Hearing Loss
  Intervention:   Device: Cochlear implant
  Sponsors:   Washington University School of Medicine;   Midwest Ear Institute;   House Clinic, Inc.;   NYU Langone Health
  Recruiting
• Cognitive Effects of Androgen Receptor Directed Therapies for Advanced Prostate Cancer

  NCT03016741

  Conditions:   Castration-Resistant Prostatic Cancer;   Metastatic Prostate Carcinoma;   Recurrent Prostate Carcinoma;   Stage IV Prostate Cancer;   Hormone-Refractory Prostate Cancer
  Interventions:   Biological: GnRH agonist/antagonist;   Drug: Prednisone;   Drug: Abiraterone Acetate;   Drug: Enzalutamide
  Sponsor:   Northwestern University
  Recruiting
• Simvastatin in Preventing Liver Cancer in Patients With Liver Cirrhosis

  NCT02968810

  Condition:   Cirrhosis
  Interventions:   Other: Laboratory Biomarker Analysis;   Other: Placebo Administration;   Other: Questionnaire Administration;   Drug: Simvastatin
  Sponsor:   National Cancer Institute (NCI)
  Recruiting
• Guadecitabine and Atezolizumab in Treating Patients With Advanced Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia That Is Refractory or Relapsed

  NCT02935361

  Conditions:   Chronic Myelomonocytic Leukemia;   Myelodysplastic Syndrome;   Recurrent Acute Myeloid Leukemia With Myelodysplasia-Related Changes
  Interventions:   Drug: Atezolizumab;   Drug: Guadecitabine
  Sponsors:   University of Southern California;   National Cancer Institute (NCI);   Van Andel Research Institute
  Recruiting
• High-Intensity Parent Intervention Program in Improving Learning and School Functioning in Latino Children With Acute Leukemia or Lymphoblastic Lymphoma

  NCT03178617

  Conditions:   Caregiver;   Childhood Acute Lymphoblastic Leukemia;   Childhood Acute Myeloid Leukemia;   Childhood Lymphoblastic Lymphoma;   Acute Leukemia;   Parent
  Interventions:   Other: Educational Intervention;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration
  Sponsors:   City of Hope Medical Center;   National Cancer Institute (NCI)
  Recruiting
• Phase I/Ib Study of Pembrolizumab With Vorinostat for Patients With Advanced Renal or Urothelial Cell Carcinoma

  NCT02619253

  Conditions:   Renal Cell Carcinoma;   Urinary Bladder Neoplasms
  Interventions:   Drug: Pembrolizumab;   Drug: Vorinostat
  Sponsor:   Roberto Pili
  Recruiting
• The Use of PRP and BMC in Patients With Internal Disc Disruption Multicenter Prospective Randomized Controlled Trial in Patients With Internal Disc Disruption

  NCT04102761

  Condition:   Internal Disc Disruption
  Intervention:   Procedure: Intradiscal PRP & BMC Injections
  Sponsors:   Annu Navani, MD;   Andrews Research & Education Foundation
  Recruiting
• The Promoting Resilience in Stress Management (PRISM) Intervention: a Multi-site Randomized Controlled Trial for Adolescents and Young Adults With Advanced Cancer

  NCT03668223

  Conditions:   Cancer;   Quality of Life;   Anxiety;   Depression;   Hope;   Coping Skills;   Communication
  Intervention:   Behavioral: Promoting Resilience in Stress Management (PRISM)
  Sponsors:   Seattle Children's Hospital;   Children's Hospital Los Angeles;   Texas Children's Hospital
  Recruiting