Migraines



Educational Intervention in Patients With Migraine


Condition:   Migraine
Interventions:   Other: Educational programme;   Other: Routine clinical practice
Sponsor:   Basque Health Service
Completed


Study of Efficacy and Safety of AMG 334 in Adult Episodic Migraine Patients


Condition:   Migraine
Interventions:   Biological: Erenumab;   Other: Placebo
Sponsor:   Novartis Pharmaceuticals
Not yet recruiting


A Study to Evaluate the Long-Term Safety of M207 in the Acute Treatment of Migraine


Condition:   Migraine
Intervention:   Drug: M207 Microneedle System
Sponsor:   Zosano Pharma Corporation
Recruiting


Open Label Safety Study in Acute Treatment of Migraine


Condition:   Migraine
Intervention:   Drug: Rimegepant
Sponsor:   Biohaven Pharmaceutical Holding Company Ltd.
Recruiting


OnabotulinumtoxinA Injections in Chronic Migraine, Targeted to Sites of Pericranial Myofascial Pain


Condition:   Chronic Migraine
Intervention:  
Sponsor:   University Hospital, Limoges
Completed


Effectiveness and Neural Mechanism of Naoan Dripping Pills for Migraine


Condition:   Migraine
Interventions:   Drug: Naoan dripping pills;   Drug: Placebo
Sponsors:   Dongzhimen Hospital, Beijing;   Liaoyuan Yulongdongya Pharmaceutical Co., Ltd.
Recruiting


Migraine Prevention Using ActiPatch


Condition:   Migraine
Interventions:   Device: Pulsed Shortwave Therapy;   Device: Placebo Pulsed Shortwave therapy
Sponsor:   BioElectronics Corporation
Recruiting


MigraineManager: An Individualized Self-Management Tool for Adolescents With Migraine


Condition:   Migraine Disorders
Intervention:   Behavioral: MigraineManager: Individualized Self-Management Tool
Sponsor:   Children's Hospital Medical Center, Cincinnati
Not yet recruiting


Intracranial Pressure During Migraine


Condition:   Menstrual Migraine
Intervention:   Other: Intracranial pressure variations
Sponsor:   University Hospital, Clermont-Ferrand
Recruiting


Melatonin for Adolescent Migraine Prevention Study


Condition:   Migraine
Interventions:   Drug: Melatonin;   Drug: Placebo oral capsule
Sponsors:   Amy Gelfand;   University of California, Los Angeles
Not yet recruiting


Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine


Condition:   Chronic Migraine
Interventions:   Drug: IONIS-PKKRx (ISIS 546254);   Other: Placebo
Sponsors:   Smith, Timothy R., M.D.;   Clinvest Research, LLC;   Ionis Pharmaceuticals, Inc.
Recruiting


Structural and Molecular Neuroplasticity in Migraine


Condition:   Migraine
Interventions:   Procedure: Pet Scan;   Procedure: MRI scan;   Procedure: Quantitative Sensory Testing (QST)
Sponsor:   University of Michigan
Completed


Investigation and Modulation of the Mu-Opioid Mechanisms in Migraine (in Vivo)


Condition:   Migraine
Interventions:   Device: Active Comparator;   Device: Sham Comparator
Sponsors:   University of Michigan;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting


Improving Health Outcomes of Migraine Patients Who Present to the Emergency Department


Condition:   Migraine
Interventions:   Drug: Preventative Medication (PM);   Behavioral: Enhanced Usual Care;   Behavioral: PMR (progressive muscle relaxation therapy)
Sponsor:   New York University School of Medicine
Not yet recruiting


Pain Processing in Adults With Migraines


Condition:   Migraines
Interventions:   Other: Questionnaires;   Other: Quantitative Sensory Testing (QST) Pain Measurements
Sponsor:   Wake Forest University Health Sciences
Recruiting


Mindfulness and Mechanisms of Pain Processing in Adults With Migraines


Condition:   Migraine
Interventions:   Other: Mindfulness Based Stress Reduction;   Other: Migraine/stress Education
Sponsor:   Wake Forest University Health Sciences
Recruiting


A Safety and Efficacy Study to Evaluate AMG 334 in Migraine Prevention


Condition:   Migraine
Interventions:   Drug: AMG 334 Dose Level 1;   Drug: Placebo;   Drug: AMG 334 Dose Level 2;   Drug: AMG 334 Dose Level 3
Sponsor:   Amgen
Active, not recruiting


Study of Key Electro-acupuncture Technique on Migraine


Condition:   Migraine
Interventions:   Device: electro-acupuncture;   Drug: flunarizine hydrochloride
Sponsor:   Shanghai University of Traditional Chinese Medicine
Recruiting


Pharmacokinetics & Safety of Cambia® in Migraine With or Without Aura in 12-17 Year Olds


Condition:   Migraine
Intervention:   Drug: Diclofenac Potassium for Oral Solution
Sponsor:   Depomed
Completed


Trial of Nortriptyline and Topiramate in the Initial Treatment of Vestibular Migraine


Condition:   Migraine Disorders
Interventions:   Drug: nortriptyline;   Drug: Topiramate
Sponsor:   St. Louis University
Recruiting


Nutrition for Migraine Prevention


Condition:   Migraine Disorders
Intervention:   Other: Diet
Sponsors:   University of North Carolina, Chapel Hill;   National Center for Complementary and Integrative Health (NCCIH)
Recruiting


A Phase 2 Study to Evaluate the Efficacy and Safety of AMG 334 in Migraine Prevention


Condition:   Migraine
Interventions:   Drug: AMG 334;   Drug: Placebo
Sponsor:   Amgen
Active, not recruiting


Ascending Single Doses of AMG 334 in Healthy Subjects and Migraine Patients


Condition:   Migraine
Intervention:   Drug: AMG 334
Sponsor:   Amgen
Completed


Normobaric Oxygen (NBO) Therapy in Acute Migraine


Condition:   Migraine
Interventions:   Biological: Oxygen;   Biological: Room air
Sponsor:   Massachusetts General Hospital
Completed


Mechanism-based Choice of Therapy for Pain: Can Successful Prevention of Migraine be Coupled to a Psychophysical Pain Modulation Profile?


Condition:   Migraine
Interventions:   Drug: Amitriptyline;   Drug: Topiramate
Sponsor:   Rambam Health Care Campus
Completed

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