Lupus (SLE)



Exploratory Study of DHA in Systemic Lupus Erythematosus Patients


Condition:   Systemic Lupus Erythematosus Cerebritis
Interventions:   Drug: Dihydroartemisinin tablet;   Drug: Placebo tablet
Sponsor:   Kunming Pharmaceuticals, Inc.
Not yet recruiting


Nicotinamide Treatment for Lupus-associated Skin Lesions in Lupus Erythematosus


Conditions:   Cutaneous Lupus Erythematosus;   Systemic Lupus Erythematosus Rash
Intervention:   Drug: nicotinamide
Sponsors:   Second Xiangya Hospital of Central South University;   National Natural Science Foundation of China;   Hunan Provincial Natural Science Foundation of China;   National Key Clinical Specialty Construction Project of China
Recruiting


Systemic Lupus Erythematosus (SLE) Prospective Observational Cohort Study (SPOCS)


Condition:   Systemic Lupus Erythematosus
Intervention:   Other: Standard of Care
Sponsor:   AstraZeneca
Recruiting


Efficacy of 595 nm Pulsed-dye Laser in Treatment of Discoid Lupus Erythematosus


Condition:   Lupus Erythematosus, Discoid
Interventions:   Device: Pulsed-dye Laser;   Device: Sham
Sponsor:   Chulalongkorn University
Recruiting


Evaluate the Safety of CS20AT04 Inj. in Subjects With Lupus Nephritis


Condition:   Lupus Nephritis
Intervention:   Biological: allogenic bone marrow derived mesenchymal stem cells
Sponsors:   Corestem, Inc.;   Hanyang University
Enrolling by invitation


Phase I Mesenchymal Stem Cells for Systemic Lupus Erythematosus


Condition:   System; Lupus Erythematosus
Intervention:   Drug: Low Dose Mesenchymal Stem Cells (MSCs)
Sponsor:   Medical University of South Carolina
Recruiting


Pilot Study to Investigate Contemplative Intervention in Lupus Patients


Condition:   Lupus Erythematosus, Systemic
Intervention:   Behavioral: Mindfulness Based Group Sessions
Sponsors:   University of Virginia;   Lupus Research Alliance
Recruiting


Aurinia Renal Response in Active Lupus With Voclosporin


Condition:   Lupus Nephritis
Interventions:   Drug: Voclosporin;   Drug: Placebo Oral Capsule
Sponsor:   Aurinia Pharmaceuticals Inc.
Recruiting


Lupus and Observance


Condition:   Systemic Lupus, Skin Lupus
Intervention:   Biological: Hydroxychloroquine dosage
Sponsor:   University Hospital Center of Martinique
Recruiting


The Iguratimod Effect on Lupus Nephritis (IGeLU)


Condition:   Lupus Nephritis
Interventions:   Drug: Iguratimod;   Drug: Cyclophosphamide;   Drug: Azathioprine;   Drug: Steroids
Sponsor:   RenJi Hospital
Recruiting


Long Term Safety of Anifrolumab in Adult Subjects With Active Systemic Lupus Erythematosus


Condition:   Active Systemic Lupus Erythematosus
Interventions:   Biological: Anifrolumab;   Drug: Placebo
Sponsors:   AstraZeneca;   PRA Health Sciences
Recruiting


The Effect of Metformin on Reducing Lupus Flares


Condition:   Systemic Lupus Erythematosus
Interventions:   Drug: metformin;   Drug: placebo
Sponsor:   RenJi Hospital
Active, not recruiting


Walk With Ease Program For Patients With Systemic Lupus Erythematosus


Condition:   Systemic Lupus Erythematosus
Intervention:   Other: "Walk With Ease"
Sponsors:   University of North Carolina, Chapel Hill;   North Carolina Translational and Clinical Sciences Institute
Recruiting


Proof-of-Concept Study With BT063 in Subjects With Systemic Lupus Erythematosus


Condition:   Systemic Lupus Erythematosus
Interventions:   Biological: BT063;   Biological: Placebo
Sponsor:   Biotest
Active, not recruiting


Safety and Efficacy of Two Doses of Anifrolumab Compared to Placebo in Adult Subjects With Active Proliferative Lupus Nephritis


Condition:   Lupus Nephritis
Interventions:   Biological: Anifrolumab;   Drug: Placebo
Sponsors:   AstraZeneca;   Parexel
Recruiting


Dose Ranging Study of Brentuximab Vedotin in Adults With Lupus


Condition:   Systemic Lupus Erythematosus
Interventions:   Drug: Brentuximab vedotin;   Drug: Placebo
Sponsor:   Seattle Genetics, Inc.
Terminated


Clinical Study to Investigate the Biological Activity, Safety, Tolerability, and Pharmacokinetics of ACT-334441 in Subjects With Systemic Lupus Erythematosus


Condition:   Systemic Lupus Erythematosus
Interventions:   Drug: ACT-334441;   Drug: Placebo
Sponsor:   Actelion
Completed


Mycophenolic Acid Pharmacokinetics and Pharmacogenomics in Lupus Nephritis


Condition:   Lupus Nephritis
Intervention:  
Sponsors:   The University of Hong Kong;   United Christian Hospital
Recruiting


Efficacy and Safety of Anifrolumab Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus


Condition:   Active Systemic Lupus Erythematosus
Interventions:   Biological: Anifrolumab;   Drug: Placebo
Sponsors:   AstraZeneca;   PRA Health Sciences
Active, not recruiting


Efficacy and Safety of Two Doses of Anifrolumab Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus


Condition:   Active Systemic Lupus Erythematosus
Interventions:   Biological: Anifrolumab;   Drug: Placebo
Sponsors:   AstraZeneca;   PRA Health Sciences
Active, not recruiting


A Phase 2a, Efficacy and Safety Study of Ustekinumab in Systemic Lupus Erythematosus


Condition:   Lupus Erythematosus, Systemic
Interventions:   Drug: Ustekinumab IV;   Drug: Placebo Infusion;   Drug: Placebo SC;   Drug: Ustekinumab SC;   Other: Concomitant Medication
Sponsor:   Janssen Research & Development, LLC
Active, not recruiting


Exploratory Study of MT-1303 in Systemic Lupus Erythematosus Patients


Condition:   Systemic Lupus Erythematosus
Interventions:   Drug: MT-1303 Low dose;   Drug: MT-1303 High dose
Sponsor:   Mitsubishi Tanabe Pharma Corporation
Completed


A Pilot Study of CC-220 to Treat Systemic Lupus Erythematosus.


Condition:   Systemic Lupus Erythematosus
Interventions:   Drug: CC-220;   Drug: Placebo
Sponsor:   Celgene
Active, not recruiting


Nelfinavir in Systemic Lupus Erythematosus


Condition:   Systemic Lupus Erythematosus
Intervention:   Drug: Nelfinavir
Sponsors:   Northwell Health;   National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruiting


Duke Lupus Registry


Conditions:   Systemic Lupus Erythematosus;   Cutaneous Lupus
Intervention:  
Sponsor:   Duke University
Recruiting

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