Down Syndrome



Role of Sleep Apnea in the Neuropsychological Function in Down Syndrome People


Condition:   Down Syndrome
Intervention:   Device: CPAP
Sponsor:   National Taiwan University Hospital
Completed


Correlation Between Optic Nerve Vessel Anomalies, Serum Angiogenic Factors and Renal Anomalies in Down Syndrome Children


Condition:   Down Syndrome
Interventions:   Diagnostic Test: Funduscopic examination and retinal photography;   Diagnostic Test: Serum levels of endostatin and angiogenesis factors;   Diagnostic Test: Renal and low urinary tract Doppler ultrasound;   Diagnostic Test: Urinalysis;   Diagnostic Test: Anthropometric measures and vitals signs
Sponsor:   Queen Fabiola Children's University Hospital
Not yet recruiting


The Impact of an 8-week Supported Exercise Program on Fitness and Symptoms in Adolescents With Down Syndrome


Condition:   Down Syndrome
Intervention:   Other: Exercise
Sponsor:   Boston Children’s Hospital
Not yet recruiting


Physiological Abnormalities Associated With Down Syndrome


Condition:   Down Syndrome
Intervention:  
Sponsors:   University of Arkansas;   Down Syndrome Research Foundation;   Arkansas Children Research Institute
Withdrawn


Effects of Karate in Adolescents With Down Syndrome


Condition:   Down Syndrome
Intervention:   Other: PKSA karate class
Sponsors:   University of Michigan;   Down Syndrome Association of Toledo
Recruiting


Treatment of Sleep Disturbances in School-age Children With Down Syndrome


Condition:   Down Syndrome
Interventions:   Behavioral: Behavioral Sleep Treatment;   Behavioral: Standard of care sleep treatment enhanced with psychoeducation
Sponsor:   Children's Hospital Medical Center, Cincinnati
Recruiting


Assessing the Feasibility of the Use of Visual Aids in Patient Education in Adults With Down Syndrome (DS)


Condition:   Down Syndrome
Interventions:   Behavioral: Verbal instructions with picture diagram;   Behavioral: Verbal instructions with video of ADSC;   Behavioral: verbal instructions w. video of w/o DS;   Behavioral: verbal instructions w. video w/DS
Sponsor:   Advocate Health Care
Active, not recruiting


Performance Analysis in Down Syndrome on Mobile Phone


Condition:   Down Syndrome
Interventions:   Behavioral: Down Syndrome Group 1;   Behavioral: Down Syndrome Group 2;   Behavioral: Typical Development Group 1;   Behavioral: Typical Development Group 2
Sponsor:   University of Sao Paulo
Completed


Safety, Tolerability and Immunogenicity of ACI-24 Vaccine in Adults With Down Syndrome


Condition:   Down Syndrome
Interventions:   Biological: ACI-24 low dose;   Biological: ACI-24 high dose;   Biological: Placebo
Sponsors:   AC Immune SA;   National Institute on Aging (NIA);   Alzheimer's Disease Cooperative Study (ADCS);   LuMind Research Down Syndrome Foundation
Recruiting


A Study of RO5186582 in Down Syndrome Among Children 6 to 11 Years of Age


Condition:   Down Syndrome
Interventions:   Drug: Placebo;   Drug: RO5186582
Sponsor:   Hoffmann-La Roche
Terminated



Investigation of the Safety of Intranasal Glulisine in Down Syndrome


Condition:   Down Syndrome
Interventions:   Drug: Insulin glulisine;   Drug: Saline
Sponsor:   HealthPartners Institute
Recruiting


Comparison of Bispectral Index Values in Patients With and Without Down's Syndrome


Condition:   Down Syndrome
Intervention:   Device: monitoring BIS in both groups
Sponsor:   Milton S. Hershey Medical Center
Recruiting


Phenotypic Specific Communication Intervention for Children With Down Syndrome


Conditions:   Language Impairment;   Down Syndrome
Intervention:   Behavioral: Jasper-EMT with words and AAC
Sponsors:   Vanderbilt University;   University of California, Los Angeles
Recruiting


Down Syndrome Biomarker Initiative (DSBI)


Conditions:   Down Syndrome;   Alzheimer's Disease
Intervention:  
Sponsors:   Michael Rafii;   Janssen Research & Development, LLC
Completed



A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS)


Condition:   Down Syndrome
Interventions:   Drug: Placebo;   Drug: RG1662
Sponsor:   Hoffmann-La Roche
Completed


DS-Connect {TM}: The Down Syndrome Registry


Condition:   Down Syndrome
Intervention:  
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Suspended



Down Syndrome Metabolic Health Study


Conditions:   Down Syndrome;   Trisomy 21
Intervention:  
Sponsors:   Children's Hospital of Philadelphia;   National Institutes of Health (NIH);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Active, not recruiting


Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children


Condition:   Down Syndrome
Intervention:   Drug: thyroid hormone and folinic acid
Sponsors:   Institut Jerome Lejeune;   Ascopharm (CRO);   Effi-stat (CRO);   AnticipSante (CRO);   LC2 (CRO);   BIOMNIS Central laboratory;   UMR INSERM 1124;   Laboratoire de Biochimie Biologie Moléculaire Nutrition Métabolisme CHU Brabois (Unité Inserm 954)
Active, not recruiting


Natural History of Amyloid Deposition in Adults With Down Syndrome


Condition:   Down Syndrome
Intervention:  
Sponsors:   University of Pittsburgh;   National Institute on Aging (NIA)
Active, not recruiting


Parent Supported Weight Reduction in Down Syndrome


Condition:   Down Syndrome
Interventions:   Behavioral: Parent Supported Behavioral Intervention;   Behavioral: Nutrition/Activity Education (NAE)
Sponsors:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   University of Massachusetts, Worcester
Completed


Treadmill Training and Orthotic Use in Infants With Down Syndrome


Condition:   Down Syndrome
Interventions:   Behavioral: Treadmill Training;   Device: Supramalleolar Orthoses
Sponsor:   University of Michigan
Completed


The Experience of Caregivers of Children With Down Syndrome


Condition:   Down Syndrome
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Completed

Refine Your Search Advanced Search