Cystic Fibrosis



Study to Evaluate the Safety & Tolerability of MRT5005 Administered by Nebulization in Adults With Cystic Fibrosis


Condition:   Cystic Fibrosis
Interventions:   Drug: MRT5005;   Drug: Normal saline
Sponsor:   Translate Bio, Inc.
Not yet recruiting


MR Imaging of Lung in the Follow-up Assessment of Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:   Device: lung MRI
Sponsors:   University Hospital, Bordeaux;   Ministry of Health, France
Not yet recruiting


Clinical Effects of Exercise Program Added to Pulmonary Rehabilitation in Patients With Cystic Fibrosis


Condition:   Cystic Fibrosis
Interventions:   Other: Active cycle of breathing techniques (ACBT);   Other: Postural Exercise
Sponsor:   Marmara University
Recruiting


Pregnancies and Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:  
Sponsor:   Hospices Civils de Lyon
Active, not recruiting


Interactive Video Game Responses in Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:  
Sponsor:   Pontificia Universidade Católica do Rio Grande do Sul
Enrolling by invitation


Nutritional Intervention and Glycemic Improvement in Patients With Pre-diabetic Cystic Fibrosis.


Conditions:   Cystic Fibrosis-related Diabetes;   Cystic Fibrosis
Intervention:   Dietary Supplement: Diet
Sponsor:   Hospital de Clinicas de Porto Alegre
Recruiting


Clearance of 25-hydroxyvitamin D in Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:   Drug: d6-25-hydroxyvitamin D3
Sponsors:   University of Washington;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting


A Study to Evaluate Safety, PK and PD of FDL169 in Cystic Fibrosis Subjects


Condition:   Cystic Fibrosis
Interventions:   Drug: FDL169;   Drug: Placebo
Sponsor:   Flatley Discovery Lab LLC
Recruiting


Sit-to-stand Test in Cystic Fibrosis Children and Adolescents


Condition:   Cystic Fibrosis
Interventions:   Behavioral: Sit-to-stand test;   Behavioral: 6-Minute Walk Test
Sponsor:   Groupe Hospitalier du Havre
Recruiting


Evaluation of Short Antibiotic Combination Courses Followed by Aerosols in Cystic Fibrosis


Condition:   Cystic Fibrosis
Interventions:   Drug: Tobi Inhalant Product;   Drug: Nebcin
Sponsor:   University Hospital, Lille
Recruiting


The Role of Oral Glutathione on Growth Parameters in Children With Cystic Fibrosis


Condition:   Cystic Fibrosis
Interventions:   Drug: Oral Glutathione;   Drug: Placebo
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   Cystic Fibrosis Foundation Therapeutics
Recruiting


Prognostic Value of Functional Exercise Test (EFX) in Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:   Other: cardiopulmonary exercise testing
Sponsor:   University Hospital, Lille
Recruiting


Aztreonam Aerosol to Treat Cystic Fibrosis Nasal Disease


Condition:   Cystic Fibrosis
Interventions:   Drug: Oral Aztreonam;   Drug: Nasal Aztreonam;   Drug: Nasal Placebo
Sponsors:   Virginia Commonwealth University;   Eastern Virginia Medical School
Recruiting


Integrating Supportive Care in Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:   Behavioral: Supportive Care Intervention
Sponsors:   University of Pittsburgh;   Cystic Fibrosis Foundation Therapeutics
Active, not recruiting


Safety, Pharmacokinetics and Pharmacodynamics Study of Inhaled QBW276 in Patients With Cystic Fibrosis


Condition:   Pulmonary Cystic Fibrosis
Interventions:   Other: Placebo;   Drug: QBW276
Sponsor:   Novartis Pharmaceuticals
Recruiting


Puberty in Girls Followed for Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:   Procedure: Data collection
Sponsor:   University Hospital, Toulouse
Completed


Observational Study of Outcomes in Cystic Fibrosis Patients With Selected Gating Mutations on a CFTR Allele (The VOCAL Study)


Condition:   Cystic Fibrosis
Intervention:   Drug: ivacaftor
Sponsor:   Vertex Pharmaceuticals Incorporated
Active, not recruiting


Glycerol Phenylbutyrate Corrector Therapy For CF (Cystic Fibrosis)


Condition:   Cystic Fibrosis
Interventions:   Drug: Ravicti low dose;   Drug: Ravicti high dose;   Drug: Placebo
Sponsors:   National Jewish Health;   University of Alabama at Birmingham;   Children's Hospital of Philadelphia;   Johns Hopkins University;   Horizon Pharma Ireland, Ltd., Dublin Ireland
Not yet recruiting


Kinetics of YKL-40 Protein in Serum of Cystic Fibrosis Patients


Condition:   Cystic Fibrosis
Intervention:  
Sponsor:   Institut de Recherches Cliniques de Montreal
Recruiting


Evaluating High Flow Humidification Therapy in Patients With Cystic Fibrosis


Condition:   Cystic Fibrosis
Interventions:   Device: High-Flow, 20 LPM (via Optiflow cannula);   Device: Low FLow, 5 LPM (via Optiflow cannula)
Sponsor:   Virginia Commonwealth University
Recruiting


Impact of Global Care of the Pain at Chronic Painful Patients Affected by Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:   Other: sophrology sessions at home
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Fondation de France
Completed


Extrapulmonary Effects of Cystic Fibrosis on Physical Activity of Adult Patients.


Condition:   Cystic Fibrosis
Intervention:  
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed


Cystic Fibrosis and Endothelial Function: At Rest and During Exercise


Condition:   Cystic Fibrosis
Interventions:   Drug: BH4 5mg;   Drug: BH4 20mg;   Dietary Supplement: Antioxidant Cocktail
Sponsor:   Augusta University
Completed


28 Day Repeat Dose in Cystic Fibrosis Patients


Condition:   Cystic Fibrosis
Interventions:   Drug: SB656933;   Drug: Placebo
Sponsor:   GlaxoSmithKline
Completed


RhDNase and Biodistribution of PMN Serine Proteases in Cystic Fibrosis Sputum


Condition:   Cystic Fibrosis
Intervention:   Drug: Pulmozyme
Sponsor:   University Hospital, Tours
Completed

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