Dry Eye Syndrome



Effectiveness of Intense Pulsed Light for Improving Dry Eye Syndrome


Condition:   Dry Eye Syndrome
Interventions:   Device: IPL;   Device: Sham IPL;   Procedure: MGX
Sponsor:   Lumenis Ltd.
Not yet recruiting


Fingerprick Autologous Blood (FAB) in Severe Dry Eye Disease (DED)


Condition:   Dry Eye Syndromes
Intervention:   Other: Fingerprick autologuos blood (FAB)
Sponsors:   Bedford Hospital NHS Trust;   Anglia Ruskin University
Not yet recruiting


Assessing the Safety and Efficacy of AVX-012 in Subjects With Mild-to-moderate Dry Eye Syndrome


Condition:   Dry Eye Syndrome
Interventions:   Drug: AVX012 Ophthalmic Solution Low dose;   Drug: AVX012 Ophthalmic Solution High dose;   Drug: Placebo (vehicle)
Sponsor:   Avizorex Pharma, S.L.
Recruiting


A Randomized, Double Masked, Clinical Study of Subjects With Dry Eye Syndrome


Condition:   Dry Eye Syndromes
Interventions:   Drug: ADX-102 Ophthalmic Solution (0.5%);   Drug: ADX-102 Ophthalmic Solution (0.1%);   Drug: ADX-102 Ophthalmic Lipid Solution (0.5%)
Sponsor:   Aldeyra Therapeutics, Inc.
Completed


Effect of Single Instillation of Three Different Topical Lubricants on Tear Film Thickness in Patients With Dry Eye Syndrome


Condition:   Dry Eye Syndromes
Interventions:   Device: Neovis Total Multi® Eye Drops;   Device: Vismed Multi® Eye Drops;   Device: Hydrabak® Eye Drops
Sponsor:   Medical University of Vienna
Recruiting


Walnut Shell Glasses Moxibustion for Dry Eye Syndrome


Condition:   Dry Eye
Interventions:   Procedure: Walnut Shell Glasses Moxibustion;   Drug: Sodium hyaluronate eye drops
Sponsor:   Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Recruiting


Safety and Efficacy of TOP1630 for Dry Eye Syndrome


Condition:   Dry Eye Syndrome
Interventions:   Drug: TOP1630 Ophthalmic Solution;   Drug: Placebo to TOP1630 Ophthalmic Solution
Sponsor:   Topivert Pharma Ltd
Completed


Cross-linked Hyaluronic Acid and Coenzyme Q10 in the Treatment of Dry Eye


Condition:   Dry Eye Syndrome
Interventions:   Device: XLHA+CoQ10;   Device: Hyaluronic acid (HA)
Sponsor:   Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Completed


Safety and Efficacy of BRM421 for Dry Eye Syndrome


Condition:   Dry Eye Syndrome
Interventions:   Drug: BRM421;   Drug: Placebo
Sponsor:   BRIM Biotechnology Inc.
Completed


Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome : ARISE-2


Condition:   Dry Eye Syndrome
Interventions:   Drug: RGN-259;   Drug: Placebo
Sponsor:   ReGenTree, LLC
Active, not recruiting


Topical Ophthalmic AGN-195263 for the Treatment of Evaporative Dry Eye


Condition:   Dry Eye Syndromes
Interventions:   Drug: AGN-195263;   Drug: Vehicle
Sponsor:   Allergan
Terminated


A Two Comparator, Controlled Phase 3 Study in Patients With and Without Evaporative Dry Eye


Condition:   Dry Eye Syndromes
Interventions:   Drug: Omega 3;   Drug: Optive Advanced;   Drug: Optive
Sponsors:   The University of New South Wales;   Allergan
Active, not recruiting


Topical Ophthalmic AGN-195263 for the Treatment of Evaporative Dry Eye


Condition:   Dry Eye Syndromes
Interventions:   Drug: AGN-195263;   Drug: Vehicle
Sponsor:   Allergan
Terminated


Effect of Nursing Care on Prevention of Dry Eye


Condition:   Dry Eye Syndromes
Interventions:   Device: LACRIBELL®;   Device: VIDISIC® GEL
Sponsors:   Diego Dias de Araújo;   State University of Montes Claros;   Conselho Nacional de Desenvolvimento Científico e Tecnológico
Recruiting


Feasibility of IPL for Reducing Dry Eye Symptoms Caused by MGD


Condition:   Dry Eye Syndromes
Intervention:   Device: M22-IPL
Sponsor:   Lumenis Ltd.
Completed


Comparison of the Efficacy and Safety of T2762 Versus Optive® in the Treatment of Moderate to Severe Dry Eye Syndrome


Condition:   Dry Eye Syndrome
Interventions:   Device: T2762;   Device: Optive
Sponsor:   Laboratoires Thea
Terminated


Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-1


Condition:   Dry Eye Syndrome
Interventions:   Drug: RGN-259;   Drug: Placebo
Sponsor:   ReGenTree, LLC
Completed


Added Benefits of Lachrymal Substitute Gel During the Night in Patients With Moderate to Severe Dry Eye Syndrome


Condition:   Dry Eye Syndromes
Interventions:   Device: Thealoz Duo Gel and Thealoz Duo eye drops;   Device: Thealoz Duo eye drops
Sponsor:   Medical University of Vienna
Completed


Effect of Benzalkonium Chloride Containing Eye Drops on the Conjunctival Bacterial Flora of Dry Eye Patients


Condition:   Dry Eye Syndromes
Interventions:   Drug: Prosicca;   Drug: Prosicca sine;   Other: Bacterial culture
Sponsor:   Medical University of Vienna
Not yet recruiting


Clinical Evaluation Following Use of SYSTANE® ULTRA in the Management of Dry Eye


Condition:   Dry Eye Syndrome
Intervention:   Drug: SYSTANE® ULTRA Lubricant Eye Drops
Sponsor:   Alcon Research
Completed


Safety and Efficacy of rhNGF Eye Drops at Different Doses in Patients With Dry Eye


Condition:   Dry Eye Syndrome
Interventions:   Biological: Human nerve growth factor 20 µg/mL;   Biological: Human nerve growth factor 4 µg/mL or 60 µg/mL
Sponsors:   Dompé Farmaceutici S.p.A;   Cross Research S.A.
Completed


Phase 2 Study to Evaluation the Safety and Efficacy of Orally Administered KL7016 in Patients With Dry Eye Syndrome


Condition:   Dry Eye Syndrome
Interventions:   Drug: KL7016 900mg;   Drug: KL7016 600mg;   Drug: Placebo
Sponsor:   Yungjin Pharm. Co., Ltd.
Completed


Efficacy and Safety of T2762 and Vismed® in Dry Eye Syndrome


Condition:   Dry Eye Syndrome
Interventions:   Device: T2762;   Device: Vismed®
Sponsor:   Laboratoires Thea
Completed


Impairment of Reading Ability in Dry Eye Patients


Condition:   Dry Eye Syndromes
Interventions:   Other: 30 minutes sustained reading;   Other: Dry eye exam
Sponsors:   Johns Hopkins University;   Allergan
Completed


Oral Omega-3 Fatty Acids in the Treatment of Dry Eye Syndrome


Condition:   Dry Eye Syndrome
Interventions:   Drug: Oral Omega-3-acid ethyl esters;   Drug: Placebo corn oil capsule
Sponsors:   Milton S. Hershey Medical Center;   The American Society of Cataract and Refractive Surgery Foundation;   GlaxoSmithKline
Completed

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