≡ Menu


About Obesity Clinical Trials (Click to Open)

Join Clinical Trials for Obesity

Clinical Trials for ObesityGeneral Purpose:

Obesity is a major health threat that has become an epidemic in this country. Living with obesity can negatively impact all aspects of your life. It can lead to depression and has an extremely negative impact on an individual’s quality of life.

Obesity cannot simply be attributed to a behavioral issue, as current clinical research is exhibiting the impact of physiology and genetics as contributing factors in causing this excess of body fat. While current interventions help some patients, not all are able to benefit.

Clinical trials for obesity are trying to prevent, treat, and increase the quality of life of those suffering from obesity. Current clinical trials are trying to decipher the effect that genes have on obesity. Studies are also evaluating different interventional methods.

These include surgical, pharmaceutical, and behavioral approaches for the treatment of obesity. Given that obesity affects over 15% of the population under 18 years of age, there are many studies on childhood obesity.

These often include identification and characterization in order to gain a better understanding of the epidemiology of this modern health crisis. If you are struggling with obesity, participating in a clinical trial is an excellent way to take a stand against obesity and make a positive impact on your health.

What will Clinical Trials for Obesity be like?

Your eligibility must first be evaluated during a screening phase to ensure that you are the Clinical Trials for Obesityright fit for the trial. The goal of these trials is to improve the quality of life of those struggling with obesity, so the researchers want to ensure that there is a potential benefit from your participation in the trial.

These criteria are also there to prevent you from experiencing any detrimental pharmaceutical interactions with another medication that you are taking. The researchers will therefore ask you to provide a very detailed medical history. They will also likely give you a clinical assessment of your current health status and determine your BMI, which should be at least 30 for eligibility in most clinical trials for obesity.

In genetic observational trials, potential participants will be given a genetic assessment to determine if there is any specific mutation present, or to retrospectively assess if there are common traits present within a large population of obese individuals enrolled in the trial. Further blood testing may also be conducted.

Typical Obesity Clinical Trial Protocol:

If the main interventional method being tested is a new pharmaceutical, you will be randomly assigned to a group that either receives a varying dose of the treatment or a placebo. If a surgical procedure is part of the treatment, participants will be randomly assigned to a group receiving an interventional surgery, such as gastric band, gastric bypass, or sleeve gastrectomy, for comparison of the benefits and drawbacks.

These trials will also often attempt to determine who benefits the most from such weight loss surgeries, which will typically enroll morbidly obese individuals. Efficacy assessments will then be conducted to evaluate the changes in obesity scores at certain time points after surgery, including potential comparisons between subgroups with co-morbid conditions like type 2 diabetes.  

A behavioral intervention trial may conduct a comparative analysis between two different forms of exercise, such as dance, to determine which best facilitates weight loss and improves health. They would determine this by having specified checkpoints throughout the duration of the study in which they obtain assessments of the treatment’s success, which may assess functional capacities – changes in gait speed, stride length, energy expenditure, etc.

Clinical trials for childhood obesity may involve educational programs for children and parents to promote healthy eating and an active lifestyle. Other studies might take an observational approach and characterize the population based on co-morbidities, quality of life, and SES to perform a longitudinal study on the development of childhood obesity.

All clinical trials will attempt to provide you personal benefit that improves your quality of life, while also using information provided by your trial experience to help cure the obesity epidemic.

Suggested Search Terms:

Childhood Obesity, Morbid Obesity, Genetics of Obesity, Surgical Intervention for Morbidly Obese Individuals, Behavioral Programs for Treating Obesity 

Current Search Term:


Add Comments or Questions