Join Clinical Trials for Migraines
Migraines are a debilitating experience that can completely stop anyone in their tracks. Unfortunately, there is no complete cure as science has yet to uncover the precise cause. There are currently approaches to both prevent migraines and ease the resulting symptoms during one.
According to research, migraine experiences worsen over time and can even become a chronic condition. Given all that remains to be understood about this elusive and incredibly painful condition, clinical research is actively recruiting participants to help elucidate the mysteries behind migraines.
Determining the appropriate formulation of medication can help prevent and treat migraines, so that is the main focus of many clinical trials for migraines. Clinical research is therefore attempting to improve the quality of life of those afflicted with migraines.
Your participation in clinical trials for migraines will enable you to gain advanced access to new and improved treatments and help extend the body of knowledge about migraines for the many sufferers of this debilitating condition.
What will Clinical Trials for Migraines be Like?
Clinical trials for Migraines will conduct screenings of each potential participant, which will include a detailed medical history of migraines that is consistent with the International Headache Society (HIS). This may be with or without an aura (the associated visual disturbances).
Depending on the specific trial, the study doctor may request additional tests for each individual. The goal is to ensure that you are the proper fit for a trial. Researchers understand the great burden of experiencing migraines, so they aim to select participants that will gain a benefit from taking part in the trial, ideally for both them and other patients struggling with this detrimental condition.
Inclusion criteria are intended to provide benefit and avoid wasting your time. Some trials may include interventional treatments that cannot be taken if a woman is pregnant or plans on becoming pregnant at any point throughout the duration of the trial.
Researchers will also likely require that you have no clinically significant abnormalities on neurological exams or clinical laboratory test results at the beginning of the trial. In order to be eligible for certain treatment groups, some trials may require potential participants to report a specified minimum number of migraines per month.
In some trials, you may have to taper and discontinue complete use of current preventative medications, while in others you may be able to rely on certain current methods should you experience a migraine during the length of the clinical trial.
Since migraines aren’t completely understood and there is no completely effective treatment available, there is an extensive range of interventional methods beings evaluated. As a result, you must make sure to pick a clinical trial that you feel comfortable participating in after reading the informed consent and learning about what it will entail.
Typical Migraine Clinical Trial Protocol:
Given the imprecise understanding of this condition and the lack of a completely effective treatment, different trial protocols may vary greatly. Most interventional studies will randomly assign you to a group. In this group, you will participate in a treatment or a control for comparison.
Most interventional trials will assess the safety and efficacy of a pharmaceutical. This may include splitting participants into varying dosage groups that will run in parallel with specified check points throughout the trial to evaluate the proper dosage. Alternatively, these trials may compare different pharmaceuticals and a placebo, following a similar outline as the aforementioned dosage determination trial.
These may include an intra-oral medication, intranasal medication, oral medication, etc. Throughout these trials, participants will likely be asked to complete a diary of their migraines, including whether or not they experience an aura, the duration of any migraines, and the details of reliance upon a rescue medication (should they be allowed to use one).
Participants may also be required to attend a clinic for assessment and blood and urine sample collection. Other studies might follow a similar outline, but instead the treatment may involve a supplement, a receptor agonist, etc.
Suggested Search Terms:
Migraine Prevention, Migraine Symptom Treatment, Dose Ranging of Migraine Prophylactic, Migraine Study in Women, Migraine With or Without an Aura
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