Healthy Volunteers



Anti-Shiga Toxin Hyperimmune Equine Immunoglobulin F(ab')2 Fragment (INM004) in Healthy Volunteers


Condition:   Healthy Volunteers
Interventions:   Biological: Drug: INM004 Dose 1;   Biological: Drug: INM004 Dose 2;   Biological: Drug: INM004- Repeated dose;   Other: Placebo
Sponsors:   Inmunova S.A.;   Hospital Italiano de Buenos Aires
Recruiting


A Study To Determine The Effect Of Single-dose PF-04965842 On QTc Interval In Healthy Volunteers Compared With Placebo and Moxifloxacin


Condition:   Healthy Volunteers
Interventions:   Drug: PF-04965842;   Drug: Moxifloxacin;   Drug: Placebo
Sponsor:   Pfizer
Not yet recruiting


A Study Using Healthy Volunteers Comparing Belatacept Which Has Been Manufactured By 2 Different Processes


Condition:   Healthy Volunteers
Intervention:   Drug: belatacept
Sponsor:   Bristol-Myers Squibb
Recruiting



SPM Regulation by Fish Oil Supplements in Healthy Volunteers


Condition:   Healthy Volunteers
Intervention:   Dietary Supplement: SPM Active
Sponsors:   Queen Mary University of London;   Metagenics, Inc.
Recruiting


The Tolerance, Pharmacokinetics of Jaktinib in Healthy Volunteers


Condition:   Healthy Volunteers
Interventions:   Drug: Jaktinib Dihydrochloride Monohydrate;   Drug: placebo
Sponsor:   Suzhou Zelgen Biopharmaceuticals Co.,Ltd
Recruiting


Single and Multiple-Ascending Dose Study of CRN00808 in Healthy Volunteers


Condition:   Healthy Volunteers
Interventions:   Drug: CRN00808;   Drug: Placebo Oral Solution;   Drug: Midazolam oral solution;   Drug: Placebo oral capsule
Sponsor:   Crinetics Pharmaceuticals Inc.
Recruiting


Study Designed to Assess the Safety, Tolerability, PK and Food Effect of PTI-808 in Healthy Volunteers


Condition:   Healthy Volunteer
Interventions:   Drug: PTI-808;   Drug: Placebo
Sponsor:   Proteostasis Therapeutics, Inc.
Recruiting


AZD1390 Administration of a Microdose [11C]AZD1390 to Healthy Volunteers


Condition:   Healthy Volunteer Male Subjects
Intervention:   Drug: [11C]AZD1390
Sponsors:   AstraZeneca;   Karolinska Institutet, Quintiles IMS
Active, not recruiting


Safety of Prasaprohyai 95%Ethanolic Extract Capsules in Healthy Volunteer


Condition:   Healthy Volunteers
Intervention:   Drug: Prasaprohyai
Sponsors:   Thammasat University;   Thai Traditional Medical Knowledge Fund
Not yet recruiting


A Phase 1 Bioavailability Study of Arbaclofen Placarbil Modified Release Formulations in Healthy Volunteers


Condition:   Healthy Volunteers
Interventions:   Drug: Arbaclofen Placarbil SR;   Drug: Arbaclofen Placarbil MR Prototype A;   Drug: Arbaclofen Placarbil MR Prototype B;   Drug: Arbaclofen Placarbil IR
Sponsor:   Indivior Inc.
Completed


Comparative Pharmacokinetics and Food-Effect Bioavailability of Lubiprostone Sprinkle in Healthy Volunteers


Condition:   Healthy Volunteers
Interventions:   Drug: Lubiprostone Capsule;   Drug: Lubiprostone Sprinkle Formulation
Sponsors:   Sucampo AG;   Sucampo Pharma Americas, LLC
Completed


Validation of a Medical Device, a Mobile Spectrofluorimeter, Measuring Skin Autofluorescence in Healthy Volunteers.


Condition:   Healthy Volunteers
Intervention:   Device: mobile spectrofluorimeter
Sponsor:   Institut de Cancérologie de Lorraine
Completed


A First-In-Human Study With a Single Dose UCB4019 in Healthy Volunteers


Condition:   Healthy Volunteers
Interventions:   Drug: PR1;   Other: PL1
Sponsor:   UCB Biopharma S.P.R.L.
Completed


Prolonged Hypoxic Breathing in Healthy Volunteers: a Safety Study


Condition:   Healthy Volunteers
Intervention:   Drug: Inhaled Nitrogen
Sponsors:   Massachusetts General Hospital;   Rezoagli, Emanuele, M.D., Massachusetts General Hospital, Harvard Medical School;   Ferrari, Michele, M.D., Massachusetts General Hospital, Harvard Medical School;   Patel, Sarvagna, B.A., Massachusetts General Hospital, Harvard Medical School;   Zapol, Warren M., M.D., Massachusetts General Hospital, Harvard Medical School;   Fisher, Daniel, R.R.T., Massachusetts General Hospital, Harvard Medical School;   Jain, Isha, B.A., Massachusetts General Hospital, Harvard Medical School;   Mootha, Vamsi, M.D., Massachusetts General Hospital, Harvard Medical School;   Harris, Stuart N., M.D., Massachusetts General Hospital, Harvard Medical School;   Karaa, Amel, M.D., Massachusetts General Hospital, Harvard Medical School
Recruiting


A Study to Assess the Relative Bioavailability And Food Effect of a Tablet Formulation of GDC-0276 in Healthy Participants


Condition:   Healthy Volunteer
Interventions:   Drug: GDC-0276 capsule;   Drug: GDC-0276 tablets
Sponsor:   Genentech, Inc.
Withdrawn


Single Ascending Dose Study to Evaluate Pharmacokinetics and Food-Effect in Healthy Volunteers


Condition:   Healthy Volunteers
Intervention:   Drug: ASN002
Sponsor:   Asana BioSciences
Completed


Safety, Tolerability, PK of Oral NYX-2925 in Healthy Volunteers


Condition:   Healthy Volunteers
Intervention:   Drug: NYX-2925
Sponsors:   Aptinyx;   Spaulding Clinical Research LLC
Completed


The Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of RO6889450 in Healthy Volunteers


Condition:   Healthy Volunteer
Interventions:   Drug: Placebo;   Drug: RO6889450
Sponsor:   Hoffmann-La Roche
Completed


A Study of HMPL-689 in Healthy Volunteers


Condition:   Healthy Volunteers
Interventions:   Drug: HMPL-689;   Drug: HMPL-689 placebo
Sponsor:   Hutchison Medipharma Limited
Completed


A Study to Investigate Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Healthy Volunteers


Condition:   Healthy Volunteer
Interventions:   Drug: DSTA4637S;   Drug: Placebo
Sponsor:   Genentech, Inc.
Completed


Open Label Phase 1 Pharmacokinetics and Tolerability Study of Single TAB08 Administration in Healthy Volunteers


Condition:   Adult Healthy Volunteers
Intervention:   Biological: TAB08
Sponsor:   Theramab LLC
Completed


Phase 2 Healthy Volunteer Study to Evaluate the Ability of PRT064445 to Reverse the Effects of Several Blood Thinner Drugs on Laboratory Tests


Condition:   Healthy Volunteers
Interventions:   Biological: PRT064445;   Biological: Placebo
Sponsor:   Portola Pharmaceuticals
Completed


ANX-042 Healthy Volunteer Dose Escalation Study


Condition:   Healthy Volunteers
Interventions:   Drug: ANX-042;   Drug: Placebo
Sponsors:   Mayo Clinic;   Anexon, Incorporated;   Celerion
Completed


Effects of Rosuvastatin on the Immune System in Healthy Volunteers With Normal Cholesterol


Condition:   Healthy Volunteers
Intervention:  
Sponsor:   National Heart, Lung, and Blood Institute (NHLBI)
Completed

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