Join Clinical Trials for Diabetes Type 1
Managing Diabetes Type 1 is a life-long responsibility. Clinical trials for Diabetes Type 1 are therefore attempting to improve the quality of life of those dealing with this autoimmune disease.
Studies of youth populations intend to learn more about the complications of diabetes and investigate the effects of care and medications. Many studies set forth to gain an improved understanding of how this disease develops in those who are at-risk.
Within this at-risk population, other studies are attempting to either delay or ideally prevent the development of Type 1 Diabetes through the use of different interventions. Some clinical trials will even have participants undergo transplantations of the cells that have been destroyed by their immune system, and will then provide medications that inhibit their immune systems from once again destroying these cells.
The intention will be to determine the combined benefit of such intervention on insulin independence, which will ideally increase. If your body does not produce insulin and you must revolve your life around your daily diabetes management, then these clinical trials should benefit you and may be worth the investment of your time.
What will Clinical Trials for Diabetes Type 1 be like?
Your eligibility must first be evaluated during a screening phase to ensure that you are the right fit for the trial. The goal of these trials is to improve the quality of life of those with Type 1 Diabetes, so inclusion criteria are intended to provide this benefit and avoid wasting your time.
They are also put in place to avoid any risk from detrimental pharmaceutical interactions with another medication that you are taking. The researchers will therefore ask you to provide a very detailed medical history. In preventative trials, participants will be given a screening for the presence of diabetes-related autoantibodies, which involves drawing a small blood sample.
Further blood testing may also be conducted to confirm eligibility. Interventional trials will assess your body’s inability to produce insulin and determine any history with severe hypoglycemia.
Typical Trial Protocol for Clinical trials for Diabetes Type 1:
If the main interventional method being tested is a new pharmaceutical, you will be randomly assigned to a group that either receives a varying dose of the treatment or a placebo.
If islet transplantation is part of the treatment, participants will wait for a preparation of islets to become available and will then be randomly assigned to one of the groups that receive medications at different time points during the transplantation process. Though there is a chance that the transplant may fail, participants in these trials may be eligible to undergo another.
To evaluate this intervention, participants will be asked to visit for follow up physical examinations, blood tests, and urine collection. While participating in these interventional studies, you will receive care and your insulin will be managed, though you may be unable to participate in other studies to avoid detrimental interactions between trial treatments.
Studies aimed at enhancing the understanding of diabetes will request many questionnaires about an individual’s health and medical conditions, with follow up physical examinations, clinical tests, and interviews.
These may include blood and urine tests, blood pressure, and measurements of height, weight, etc. These studies will require minimal effort in comparison to interventional studies, but will help to provide a large database of information for researchers to draw conclusions from to help improve the lives of those afflicted with diabetes.
Preventative trials will randomly assign participants to a group that will either receive the potential preventative treatment or a placebo. Follow up visits will require blood and other clinical tests depending on the specific trial.
Since relatives of people with type 1 Diabetes are 10 to 15 times more likely to develop this autoimmune disease, these clinical trials are beneficial to you as they may be able to determine your estimated risk for disease development. You will also be providing critical insight into how this disease develops in at-risk individuals.
Suggested Search Terms:
Type 1 Diabetes in Youth, Type 1 Diabetes and Insulin Resistance, Prevention of Type 1 Diabetes, Islet Transplantation for Type 1 Diabetes, Blood Sugar and Type 1 Diabetes