Chronic Pain

About Chronic Pain Clinical Trials (Click to Open)

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Clinical Trials for Chronic PainGeneral Purpose:

Living with chronic or acute pain can negatively impact all aspects of your life. Clinical trials for chronic pain are trying to improve the quality of life of those struggling to make it through each day despite their debilitating condition.

Current clinical trials are therefore trying to determine the safety and efficacy of interventional treatment methods for pain management. These range from medications and analgesics to acupuncture. Trials will also assess the benefit of different behavioral interventions, such as chronic pain group therapy.

In addition to interventional trials, there are also many observational trials intending to develop new techniques to characterize the physiological changes that are indicative of both chronic and acute pain.

Clinical trials for chronic pain will enhance the scientific body of knowledge surrounding the negative impact that pain has on its sufferers, thereby enhancing the ability of science to treat it.  

What will Clinical Trials for Chronic Pain be like?

Clinical trials for pain will conduct assessments of each potential participant’s pain rating, generally determined based on a numerical rating scale value greater than 3. This may include a physical exam and detailed medical history.

You will be asked to report on your painful symptoms, which may include information regarding a surgery with moderate to severe pain, extremity bone fracture, a somatosensory disease, etc.

Researchers understand the impedance of living with depression, so they aim to select participants that will gain a benefit from taking part in the trial, ideally for them and other patients struggling with this detrimental condition.

Inclusion criteria are intended to provide benefit and avoid wasting your time. The goal is to ensure that you are the proper fit for a trial and to reduce any potential risk.

Typical Pain Clinical Trial Protocol:

Pharmaceutical intervention trials will start by first randomly assigning participants to a Clinical Trials for Chronic Paingroup that either receives a varying dose of the treatment or a placebo. You will then be asked to report on your symptoms so that potential benefit can be evaluated.

In chronic pain therapy trials, comparison will be made between the self-reported baseline measurements, which might include anything from physical to emotional functioning, and specified time point assessments taken throughout the trial.

Acute pain trials will follow a similar outline. You should also note that as with any clinical trial, it is possible that you will be randomly selected for the placebo group. You would therefore undergo the same procedures as the treatment group without receiving the actual treatment being tested.

If it is a behavioral intervention trial, participants will be assigned to a group receiving the behavior or a control to evaluate the benefit of the treatment method. Participants will then receive questionnaires to assess the efficacy of the program, quality of life evaluation, health care utilization, and further outcome measures dependent on the specific pain trial.

The ultimate goal of clinical trials for chronic pain is to benefit those suffering from acute and chronic pain, so all trials will work relentlessly to meet that end.

Suggested Search Terms:

Chronic Pain Management, Pain Relief after Acute Injury, Chronic Pain Group Therapy, Alternative Medicine Approach to Pain Treatment, Analgesics for Pain Treatment

Current Search Term:

“Chronic Pain”

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The Pain App Study: A Novel Shared Decision Making Tool for People With Chronic Pain


Condition:   Chronic Pain
Intervention:   Other: Interactive decision support tool
Sponsors:   Shared Decision Making Resources;   University of New England;   Pfizer
Enrolling by invitation


Digital Signals in Chronic Pain (DiSCover Project)


Condition:   Chronic Pain
Intervention:   Other: No intervention
Sponsor:   Evidation Health
Recruiting


Internet-based Acceptance and Commitment Therapy for Chronic Pain


Condition:   Chronic Pain
Interventions:   Behavioral: ALGEApp (Brief iACT intervention);   Behavioral: Active control group
Sponsor:   University of Cyprus
Not yet recruiting


Mindfulness Self-Compassion Intervention Versus a Cognitive-Behavioral Intervention to Improve Self-care in Chronic Pain


Condition:   Chronic Pain
Interventions:   Behavioral: MSC;   Behavioral: CBT
Sponsor:   Instituto de Investigación Hospital Universitario La Paz
Active, not recruiting


Chronic Pain Skills Study - Vanderbilt University Medical Center


Condition:   Chronic Pain
Interventions:   Behavioral: Clinical Hypnosis - Group Treatment;   Behavioral: Clinical Hypnosis - Individual Treatment
Sponsor:   Vanderbilt University Medical Center
Recruiting


WebMAP Mobile Self-management of Adolescent Chronic Pain


Condition:   Chronic Pain
Intervention:   Behavioral: Cognitive-behavioral intervention for chronic pain
Sponsors:   Seattle Children's Hospital;   Connecticut Children's Medical Center;   Children's Mercy Hospital Kansas City;   C.S. Mott Children's Hospital;   Nationwide Children's Hospital
Not yet recruiting


OBSERVATIONAL STUDY OF THE MANAGEMENT OF PATIENTS WITH CHRONIC PAIN


Condition:   Chronic Pain
Intervention:   Other: ketamine
Sponsor:   University Hospital, Clermont-Ferrand
Recruiting


Behavioral Interventions for Chronic Pain and Opioid-Related Problems


Condition:   Chronic Pain
Interventions:   Behavioral: Mindfulness-Oriented Recovery Enhancement;   Behavioral: Supportive Counseling
Sponsor:   University of Utah
Recruiting


Efficacy of Pain Monitor, a Smartphone App for Chronic Pain


Condition:   Chronic Pain
Interventions:   Other: pain app;   Other: Treatment as usual (medical)
Sponsor:   Universitat Jaume I
Recruiting


Chronic Pain After Childbirth - Caesarean Section Compared to Vaginal Delivery and the Impact of Pre-existing Pain


Condition:   Chronic Pain
Intervention:  
Sponsor:   University Hospital Tuebingen
Completed


Use of PET/MR Imaging in Chronic Pain


Condition:   Chronic Pain
Interventions:   Drug: [18F]FDG;   Device: PET/MRI
Sponsors:   Stanford University;   GE Healthcare
Recruiting


Nature as a Buffer Among People With Chronic Pain


Condition:   Chronic Pain
Interventions:   Other: Natural Environment;   Other: Built Environment
Sponsor:   Cornell University
Active, not recruiting


Internet-delivered ACT for Chronic Pain


Condition:   Chronic Pain
Interventions:   Behavioral: Internet delivered Acceptance and Commitment therapy;   Behavioral: Waiting list control condition
Sponsors:   Rikard Wicksell;   AFA Insurance
Active, not recruiting


Adaptation of Mindfulness Training to Treat Chronic Pain in the Military


Condition:   Chronic Pain
Intervention:   Behavioral: Mindfulness Training
Sponsors:   RTI International;   University of North Carolina, Chapel Hill
Recruiting


Social & Behavioral Rhythms in Chronic Pain


Condition:   Chronic Pain
Interventions:   Behavioral: Interpersonal Social Rhythms Psychotherapy;   Device: Bright Light Device
Sponsor:   University of Utah
Completed


Chronic Pain and Assessment of Sleep


Condition:   Chronic Pain
Intervention:   Other: Sleep assessment tools
Sponsors:   University of Aberdeen;   NHS Grampian
Completed


Objective Pain Score for Chronic Pain Clinic Patients


Condition:   Chronic Pain
Intervention:   Behavioral: Pain Assessment
Sponsor:   Milton S. Hershey Medical Center
Active, not recruiting


Our Whole Lives: Online Chronic Pain Management


Condition:   Chronic Pain
Intervention:   Behavioral: Our Whole Lives Website
Sponsors:   Boston Medical Center;   Aetna, Inc.
Completed


The Chronic Pain Incidence After Elective and Urgent Cesarean Sections


Condition:   Chronic Pain
Intervention:  
Sponsor:   Tokat Gaziosmanpasa University
Completed


Mobile Phone Technology for Chronic Pain Patients- A Feasibility Study


Condition:   Chronic Pain
Interventions:   Other: Electronic Diary;   Other: Questionnaire
Sponsor:   Weill Medical College of Cornell University
Terminated


Algovita Post-Market Clinical Study: Spinal Cord Stimulation to Treat Chronic Pain


Condition:   Chronic Pain
Intervention:   Device: Algovita Spinal Cord Stimulation system
Sponsor:   Nuvectra
Recruiting


Open-Label Safety and PK Study of ER Hydromorphone Tablets in Opioid-Tolerant Pediatric Chronic Pain Patients


Condition:   Chronic Pain
Intervention:   Drug: Hydromorphone HCl ER Tablets
Sponsor:   Mallinckrodt
Recruiting


Mind Body Syndrome (MBS) Therapy for the Treatment of Chronic Pain


Condition:   Chronic Pain
Intervention:   Behavioral: One-on-one interview and educational sessions. Reading material for educational series as below
Sponsor:   Beth Israel Deaconess Medical Center
Recruiting


An Interventional Study to Compare the Efficacy and Tolerability With Targin® in Non-malignant Chronic Pain (GLORY)


Condition:   Chronic Pain
Intervention:   Drug: Oxycodone/naloxone
Sponsor:   Mundipharma Korea Ltd
Completed


Web-based Cognitive-behavior Therapy (CBT) for Opioid-treated, Chronic Pain Patients With Aberrant Behavior


Condition:   Chronic Pain
Intervention:   Behavioral: Web-based CBT for chronic pain
Sponsors:   National Development and Research Institutes, Inc.;   National Institute on Drug Abuse (NIDA);   Beth Israel Medical Center
Completed

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2 thoughts on “Chronic Pain

  1. looking for long term study for relief low back pain with opioids, BEMA,R oxycotin or oxy IR in birmingham alabama. Need medication medicare will not pick up till Oct.2012. Been in pain management since 15 years ago. on disability now and no health insurance.REALLY NEED HELP WITH PAIN CONTROL.
    debbieb

    • Hi Deborah,
      I’m so sorry to hear about your pain situation, back pain is one of the most difficult things to manage. We can not recommend a particular trial for you, however, here is the process to follow to find a trial that you may be eligible for: 1)Fill out a clinical trial profile on JCT to help recruiters find you. 2) Type ‘back pain’ in the search box, choose your state, then choose ‘open studies’ and click submit to pull up the results. Several options should appear for the state of Alabama. I wish you the best of luck and hope that things get better.