Anemia

About Anemia Clinical Trials (Click to Open)

Join Clinical Trials for Clinical Trials for Anemia

Clinical Trials for AnemiaIn clinical trials for anemia, medications will be tested that should ideally help treat the different forms of anemia, as well as improve the quality of life of those afflicted with this disease.

They will also test blood and marrow stem cell transplants for those with severe forms, the effectiveness of bone marrow treatments for children with sickle cell disease, medication to improve blood counts for those with aplastic anemia, and gene therapy for those with Fanconi anemia.

What is a typical trial like?

Potential study participants will undergo blood tests to determine eligibility. Tests such as blood counts assessments will be administered for comparison purposes with future tests to determine the success rate of treatments. Certain trials will also require evidence of a family history with inherited forms of anemia in order for you to be eligible.

Typical Trial Protocol:

Participants may receive some form of medication intravenously for a specified time course, during which they may be continuously monitored in the associated research hospital with the intention of studying drug initiation.

In FDA approved drug trials, participants may take the approved prescription pill for the recommended duration and be monitored while on the medication. They will also be required to attend follow-ups for a specified time after stopping the medication.

Those with severe forms of inherited anemia may be eligible to join a clinical trial in which they will undergo stem cell transplant and post transplant therapy to reduce the risk of host versus graft disease. Assistance will be provided for the cost of living away from home during the course of the procedure and post-procedural therapy.

You should also note that as with any clinical trial, it is possible that you will be randomly selected for the placebo group. You would therefore undergo the same procedures as the treatment group without receiving the actual treatment being tested.

Suggested Search Terms:

Aplastic Anemia, Sickle Cell Anemia, Diamond Blackfan Anemia, Gene therapy and Fanconi Anemia, Stem Cell Transplants for Anemia 



Pilot Study of Metformin for Patients With Fanconi Anemia


Condition:   Fanconi Anemia
Intervention:   Drug: metformin HCl
Sponsor:   Boston Children’s Hospital
Not yet recruiting


A Study Comparing Two Ferric Carboxymaltose Formulations in Patients With Iron Deficiency Anemia


Condition:   Iron Deficiency Anemia
Intervention:   Drug: Ferric carboxymaltose
Sponsor:   Sandoz
Recruiting


FANC-A Gene Transfer for Fanconi Anemia Using a Self-inactivating Lentiviral Vector


Condition:   Fanconi Anemia
Intervention:   Genetic: Gene-modified autologous stem cells
Sponsor:   Shenzhen Geno-Immune Medical Institute
Recruiting


Anemia in Othropedic Surgery - Determination of Hb


Condition:   Anemia
Intervention:   Device: Hemocue and Rad-67 measurement
Sponsor:   Theusinger Oliver M.
Recruiting


Intravenous Treatment of Anemia in Pregnancy


Condition:   Anemia
Interventions:   Drug: iron sucrose (200 mg VENOFER®);   Drug: recombinant human erythropoietin (10,000 U EPREX®)
Sponsor:   University of Zurich
Completed


Haploidentical Transplantation in Severe Aplastic Anemia


Condition:   Severe Aplastic Anemia
Interventions:   Other: MSD-HSCT;   Other: HFD-HSCT
Sponsor:   Wu Xiaoxiong
Enrolling by invitation


Clinical Study of Non Severe Aplastic Anemia Treated With Cyclosporine, Androgen and Levamisole


Condition:   Aplastic Anemia
Interventions:   Drug: levamisole hydrochloride;   Drug: Androgens;   Drug: Cyclosporins
Sponsor:   Shengyun Lin
Recruiting


Iron Dextran Versus Oral Iron for Treating Iron Deficiency Anemia in Pregnant Women


Condition:   Anemia
Interventions:   Drug: Iron dextran;   Drug: Ferrous Fumarate
Sponsor:   Assiut University
Completed


Bovine Lactoferrin Versus Ferrous Sulphate In The Treatment Of Iron Deficiency Anemia During Pregnancy


Condition:   Anemia During Pregnancy
Interventions:   Dietary Supplement: L (lactoferrin);   Drug: F (ferrous sulphate)
Sponsor:   Abdelwahed, Mai Mahmoud Mohamed, M.D.
Recruiting


The Burden of Childhood Anemia in Bangladesh: Does Socioeconomic Status Matter?


Condition:   Anemia
Intervention:   Diagnostic Test: Anemia
Sponsor:   Shahjalal University of Science and Technology
Completed


Burden of Anemia Among Ever-married Women in Bangladesh: Does Household Economic Inequality Matter?


Condition:   Anemia
Intervention:  
Sponsor:   Shahjalal University of Science and Technology
Completed


Improving Anemia Status of Female Garment Workers in Bangladesh: An Evaluation of Pilot Intervention in Four Factories


Condition:   Anemia
Interventions:   Combination Product: Intervention factory with hot lunch;   Combination Product: Intervention factory without lunch program;   Combination Product: Control factory with lunch program;   Behavioral: Control factory without lunch program
Sponsor:   International Centre for Diarrhoeal Disease Research, Bangladesh
Active, not recruiting


Anemia Studies in Chronic Kidney Disease (CKD): Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor (PHI) Daprodustat-in Incident Dialysis (ASCEND-ID)


Condition:   Anaemia
Interventions:   Drug: Daprodustat;   Drug: Darbepoetin alfa;   Drug: Iron therapy
Sponsor:   GlaxoSmithKline
Recruiting


Iron Sucrose Versus Ferrous Bis-glycinate for Treatment of Iron Deficiency Anemia


Condition:   Anemia
Interventions:   Drug: Iron Sucrose Injection;   Drug: Ferrous Bisglycinate
Sponsor:   Assiut University
Recruiting


ORthopaedic Trauma Anemia With Conservative Versus Liberal Transfusion


Condition:   Anemia
Intervention:   Biological: Blood and blood products for transfusion
Sponsors:   Indiana University;   Atlanta Medical Center;   Louisiana State University Health Sciences Center in New Orleans
Enrolling by invitation


Study of Romiplostim(AMG531) in Subjects With Aplastic Anemia


Condition:   Aplastic Anemia
Intervention:   Biological: Romiplostim
Sponsor:   Kyowa Hakko Kirin Co., Ltd
Active, not recruiting


Efficacy and Safety of Eltrombopag + CSA in Patients With Moderate Aplastic Anemia (EMAA)


Condition:   Anemia, Aplastic
Interventions:   Drug: Eltrombopag;   Drug: Placebo (for Eltrombopag)
Sponsor:   B. Höchsmann
Recruiting


Use of Cast Iron Pots to Improve Maternal Anemia


Condition:   Iron-deficiency Anemia
Interventions:   Device: Cast Iron Pot;   Device: Alumnium Pot
Sponsor:   Weill Medical College of Cornell University
Recruiting


Safety and Efficacy Study of Roxadustat to Treat Anemia in Patients With Chronic Kidney Disease, on Dialysis


Condition:   Anemia
Interventions:   Drug: Roxadustat;   Drug: Epoetin alfa
Sponsors:   AstraZeneca;   FibroGen
Recruiting


Study of Beet Juice for Patients With Sickle Cell Anemia


Condition:   Sickle Cell Anemia
Intervention:   Drug: beet juice (Unbeetable)
Sponsors:   Wake Forest University Health Sciences;   Wake Forest University;   National Heart, Lung, and Blood Institute (NHLBI)
Suspended


Effects of Vitamin D and Marine Omega-3 Fatty Acids on Anemia


Condition:   Anemia
Interventions:   Dietary Supplement: Vitamin D3 .;   Drug: omega-3 fatty acids (fish oil);   Dietary Supplement: Vitamin D3 placebo;   Dietary Supplement: Fish oil placebo
Sponsors:   Brigham and Women's Hospital;   National Heart, Lung, and Blood Institute (NHLBI);   Office of Dietary Supplements (ODS);   National Center for Complementary and Integrative Health (NCCIH)
Enrolling by invitation


Mechanisms Accounting for Unexplained Anemia in the Elderly


Condition:   Anemia
Intervention:   Procedure: Biotin RBC survival
Sponsor:   National Institute on Aging (NIA)
Completed


Gene Function in Bone Marrow Cells From Patients With Fanconi Anemia and From Healthy Participants


Condition:   Fanconi Anemia
Interventions:   Genetic: microarray analysis;   Procedure: biopsy
Sponsors:   OHSU Knight Cancer Institute;   National Cancer Institute (NCI)
Terminated


Study to Assess the Efficacy and Safety of HX575 in the Treatment of Chemotherapy Associated Anemia in Cancer Patients


Condition:   Anemia
Interventions:   Drug: HX575, solution for injection (s.c.);   Drug: ERYPO®, Janssen-Cilag, solution for injection (s.c.)
Sponsors:   Sandoz;   Hexal AG
Completed


Study to Evaluate the Efficacy and Safety of HX575 Hexal AG vs ERYPO® for the Treatment of Anemia in Hemodialysis Patients


Condition:   Anemia
Interventions:   Drug: HX575 epoetin alfa Hexal AG;   Drug: ERYPO®, Janssen-Cilag
Sponsors:   Sandoz;   Hexal AG
Completed

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