Underactive Thyroid

Clinical Trials for Underactive Thyroid Gland (Hypothyroidism)

Clinical Trials for Underactive Thyroid Gland (Hypothyroidism)

General purpose

Research related to thyroid gland activity may investigate the role that genetics has in the development of the condition – in particular for children – as well as why women are more often affected than men.

In addition, some research may focus on certain viral or bacterial exposures that trigger the body’s immune system to attack the thyroid gland.

Research may also seek to better understand the role that pregnancy has in causing hypothyroidism, as well as the possible relationship between hypothyroidism and infertility.

Underactive Thyroid Clinical Trials Continued (Click to Open)

Clinical Trials for Underactive Thyroid Gland (Hypothyroidism)

Underactive Thyroid Gland

What do clinical trials for Hypothyroidism involve?

Clinical trials will vary widely in the information they collect, as well as the tests and procedures they use. All of these factors will depend on individual study designs, which will differ greatly between trials.

However, below is a list of common procedures and data that are frequently collected during a trial for hypothyroidism:

  • Blood tests to measure
    • Levels of the hormones TSH and thyroxine
    • Cholesterol
    • Genetic factors
    • Complete blood count
    • Liver enzymes
    • Prolactin levels
    • Sodium
  • Chest x-ray to examine heart
  • Assessments of how hypothyroidism affecting the patient’s quality of life.

Examples of Hypothyroidism- related research topics:

  • Studies comparing new diagnostic methods for detecting hypothyroidism to determine which one is the most sensitive and accurate.
  • Studies designed to determine the risk of heart failure and other cardiovascular disease among patients with hypothyroidism.
  • Studies that investigate lifestyle changes to help patients with hypothyroidism better manage their symptoms (such as fatigue, weight gain, cold intolerance, and depression).
  • Studies that investigate the reason why individuals with other autoimmune diseases (such as type 1 diabetes, rheumatoid arthritis, or lupus) are at an increased risk of developing hypothyroidism.
  • Studies investigating new drugs that can treat rheumatoid arthritis with fewer side effects than conventional treatments.

Suggested search terms for best results: 

“Underactive Thyroid Gland ““underactive thyroid [or hypothyroidism] pregnancy,” “underactive thyroid [or hypothyroidism] congenital,” “underactive thyroid [or hypothyroidism] treatment,” “underactive thyroid [or hypothyroidism] heart,” and “underactive thyroid [or hypothyroidism] depression.” 


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