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Join Clinical Trials for Scleroderma

General purpose:  Clinical trials for Scleroderma may study the role of the immune system in its development, alternative therapies for its treatments, and how it impacts the skin, blood vessels, muscles, and internal organs.

Scleroderma research also seeks to discover the cause of the condition, its relationship to other autoimmune diseases (such as rheumatoid arthritis and lupus), as well as why it occurs most often in women.

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Clinical Trials for Rheumatoid Arthritis

What do clinical trials for Scleroderma involve?

Clinical trials will vary widely in the information they collect, as well as the tests and procedures they use. All of these factors will depend on individual study designs, which will differ greatly between trials.

However, below is a list of common procedures and data that are frequently collected during a trial for scleroderma:

  • Physical exam to evaluate the condition of the skin.
  • Blood pressure checks (as scleroderma can cause inflammation in the blood vessels of the kidneys and other organs).
  • Blood tests such as the following:
  • Antinuclear antibody (ANA) panel
  • Antibody testing
  • ESR / sed rate
  • Rheumatoid factor
    • Chest x-ray
    • Computed tomography (CT) scan of the lungs
    • Echocardiogram (EKG)
    • Urine tests
    • Lung function tests
    • Skin biopsies

Examples of scleroderma- related research topics:

  • Studies investigating new treatments for the symptoms associated with scleroderma.
  • Studies investigating the use of a pregnancy-related hormone called relaxin to soften connective tissues in women with scleroderma.
  • Studies designed to evaluate common genetic factors among individuals with scleroderma in order to identify genetic mutations associated with an increased risk of developing the condition.
  • Investigating the effectiveness of new drugs to treat the lung symptoms associated with scleroderma.
  • Investigating the effectiveness of drugs to treat and prevent kidney failure in patients with scleroderma.
  • Studies investigating the role of malfunctioning blood vessels, cellular death, and autoimmune system dysfunction in scleroderma.

Suggested search terms for best results: 

Scleroderma” “scleroderma kidneys” “scleroderma lungs,” “scleroderma treatment,” “scleroderma skin,” “scleroderma blood pressure,” and “scleroderma hormones.”