Food Allergies

Food Allergy Clinical TrialsFood Allergy Clinical Trials

General Purpose: Allergic symptoms arise when the immune system becomes over-sensitized (i.e., over-reactive) to a particular allergen or irritant. In the case of food allergies, an abnormal response of the body’s immune system to foods such as peanuts, shellfish, and milk can result in an allergic reaction.

Allergic reactions can vary from skin irritation to more serious complications including gastrointestinal disorders and anaphylaxis, which could also result in anaphylactic shock. The purpose of food allergy trials often examines the role of white blood cells in disease in order to determine how the immune system responds to a particular food allergy.

To prevent allergic reactions from food allergies, industries also run trials on large groups to determine the minimum eliciting dose of the allergic response.

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What are Typical Food Allergy Clinical Trials Like?

Trial participants will undergo screening that involves a physical examination and medical history. In addition, blood samples will be collected to determine each individual’s sensitivity to the allergens being studied.

Additional tests may be performed to determine the participant’s level of sensitivity to particular foods, as well as stool sample testing for those participants who have eosinophil-associated gastrointestinal disorders.

Typical Trial Protocol for Food Allergy Clinical Trials:

Some studies seek to decrease the reaction of the immune system by gradually exposing individuals to small amounts of allergens over an extended period of time, in an effort to increase an individual’s tolerance.

This is known as immunotherapy. Immunotherapy trials can be lengthy, and may span over the course of several years. During these trials, individual participants’ tolerance to the allergen or allergens being studied will be assessed via blood tests at specified time points.

Other allergy-related trials may seek to determine the amount of exposure to a particular allergen that is required in order to elicit an allergic response. Trials such as this may also randomly assign some participants to receive a placebo, so that the results between the allergen and placebo group can be compared.

As a result, those in the placebo group would receive the same protocol procedures that the allergen group received, however they would not be exposed to the actual allergen being studied.

Suggested Search Terms

Food Allergies, Food Hypersensitivity, Peanut Hypersensitivity, Pediatric Diseases, Gastrointestinal Diseases.

Current Search Term: “Food Allergy”