Restless Legs Syndrome



Treatment of RLS/WED Symptoms Through Sensory Counter-stimulation


Conditions:   Restless Legs Syndrome;   Willis-Ekbom Disease
Intervention:   Device: Scrambler
Sponsor:   Mayo Clinic
Recruiting


Treatment of Restless Leg Syndrome (RLS) Augmentation With Ecopipam, a D1 Specific Antagonist


Conditions:   Restless Legs Syndrome;   Augmentation
Interventions:   Drug: Ecopipam;   Drug: Placebo
Sponsors:   William Ondo, MD;   Restless Legs Syndrome Foundation
Not yet recruiting


A Study of Oral Dosing of Gabapentin Enacarbil in Japanese Restless Legs Syndrome Patients


Condition:   Restless Legs Syndrome (RLS)
Interventions:   Drug: Gabapentin enacarbil;   Drug: Placebo
Sponsor:   Astellas Pharma Inc
Recruiting


A Study on the Use of the MMF07 Foot Massager and Heat Therapy Treatments for Restless Leg Syndrome


Condition:   Restless Legs Syndrome
Interventions:   Device: MMF07 Foot Massager;   Device: Heat Therapy
Sponsors:   Ariane Park;   MedMassager
Recruiting


Placebo-Controlled Study to Investigate the Efficacy & Safety of Injectafer in the Treatment of RLS


Condition:   Restless Legs Syndrome (RLS)
Interventions:   Drug: Injectafer;   Other: Placebo
Sponsor:   Luitpold Pharmaceuticals
Active, not recruiting


Autonomic Function and Cardiovascular Risk in Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Interventions:   Drug: Pramipexole;   Drug: Placebo
Sponsors:   Mauro Manconi;   University Hospital Inselspital, Berne;   Cardiocentro Ticino
Completed


Post-marketing Study of Gabapentin Enacarbil to Evaluate the Effect in Restless Leg Syndrome (RLS) Patients With Moderate Renal Impairment


Condition:   Restless Legs Syndrome (RLS)
Intervention:   Drug: Gabapentin enacarbil
Sponsor:   Astellas Pharma Inc
Completed


Glutamate, Hyperarousal and Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Intervention:  
Sponsors:   Johns Hopkins University;   National Institutes of Health (NIH)
Completed


Safety and Efficacy Study of IPX159 in Restless Legs Syndrome (RLS)


Condition:   Restless Legs Syndrome
Interventions:   Drug: IPX159;   Drug: Placebo
Sponsor:   IMPAX Laboratories, Inc.
Completed


Long-Term Follow-Up Study for Safety, Efficacy and Tolerability of Rotigotine in Adolescents With Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Intervention:   Drug: Rotigotine
Sponsor:   UCB BIOSCIENCES, Inc.
Completed


Efficacy of Tyrosine in Restless Legs Syndrome


Condition:   Restless Legs Syndrome (RLS)
Intervention:   Dietary Supplement: L-Tyrosine
Sponsor:   Seton Healthcare Family
Completed


REQUIP RLS Post Marketing Surveillance


Condition:   Restless Legs Syndrome
Intervention:   Drug: Ropinirole
Sponsor:   GlaxoSmithKline
Completed


Study of Vitamin C, Vitamin E and Their Combination to Treat Restless Legs Syndrome in Hemodialysis Patients


Conditions:   Restless Legs Syndrome;   Kidney Failure, Chronic
Interventions:   Drug: Vitamin C & Vitamin E;   Drug: Vitamin C;   Drug: Vitamin E;   Drug: Vitamin C Placebo & Vitamin E Placebo
Sponsor:   Shiraz University of Medical Sciences
Completed



Intravenous Iron Metabolism in Restless Legs Syndrome


Condition:   Restless Legs
Interventions:   Drug: Ferric Carboxymaltose (FCM);   Drug: Placebo
Sponsors:   Luitpold Pharmaceuticals;   National Institute on Aging (NIA)
Completed


Clinical Evaluation of Ropinirole CR-RLS ( SK&F101468)Tablets in Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Intervention:   Drug: ropinirole controlled release (CR)-RLS
Sponsor:   GlaxoSmithKline
Completed


Restless Legs Patient Study On Absorption, Distribution, Metabolism And Excretion Of Ropinirole And The Effect Of Food


Condition:   Restless Legs Syndrome
Intervention:   Drug: Ropinirole
Sponsor:   GlaxoSmithKline
Completed


12-week Polysomnography Study of Ropinirole Controlled Release for Restless Legs Syndrome


Conditions:   Restless Legs Syndrome (RLS);   Restless Legs Syndrome
Intervention:   Drug: ropinirole CR-RLS
Sponsor:   GlaxoSmithKline
Completed


Long-Term Safety Of Ropinirole XR In Patients With Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Intervention:   Drug: Ropinirole Extended Release (XR)
Sponsor:   GlaxoSmithKline
Completed


Long-term Study Of Ropinirole In Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Interventions:   Drug: Placebo;   Drug: Ropinirole
Sponsor:   GlaxoSmithKline
Completed


RLS In Adults: Comparing Immediate Release Formulation With Extended Release Formulation Of Ropinirole


Conditions:   Restless Legs Syndrome;   Restless Legs Syndrome (RLS)
Intervention:   Drug: ropinirole Extended Release (XR)
Sponsor:   GlaxoSmithKline
Completed


Converting From Ropinirole Immediate Release (IR) To Ropinirole Controlled-Release for RLS (Restless Legs Syndrome)


Conditions:   Restless Legs Syndrome;   Restless Legs Syndrome (RLS)
Intervention:   Drug: ropinirole controlled-release for RLS
Sponsor:   GlaxoSmithKline
Completed


Ropinirole Tablets In Young Patients With Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Intervention:   Drug: Ropinirole Immediate Release
Sponsor:   GlaxoSmithKline
Completed


Relationship Between Sensory and Motor Systems in Restless Leg Syndrome


Condition:   Restless Legs Syndrome
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed


Effect of Ropinirole on Spinal Cord Reflexes and Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed

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