Restless Legs Syndrome



A Study of Oral Dosing of Gabapentin Enacarbil in Japanese Restless Legs Syndrome Patients


Condition:   Restless Legs Syndrome (RLS)
Interventions:   Drug: Gabapentin enacarbil;   Drug: Placebo
Sponsor:   Astellas Pharma Inc
Recruiting - verified May 2017


Randomized, Placebo-controlled Trial of Ferric Carboxymaltose in RLS Patients With Iron-deficiency Anemia


Condition:   Restless Legs Syndrome (RLS)
Interventions:   Drug: Injectafer® (Ferric Carboxymaltose - FCM);   Drug: Placebo (Normal Saline)
Sponsor:   Luitpold Pharmaceuticals
Recruiting - verified May 2017


A Study on the Use of the MMF07 Foot Massager and Heat Therapy Treatments for Restless Leg Syndrome


Condition:   Restless Legs Syndrome
Interventions:   Device: MMF07 Foot Massager;   Device: Heat Therapy
Sponsors:   Ariane Park;   MedMassager
Recruiting - verified September 2016


Cranial Electrotherapy for Military Beneficiaries With Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Interventions:   Device: Active CES Device Alpha-Stim®;   Device: Sham Device
Sponsors:   Tripler Army Medical Center;   University of Virginia
Active, not recruiting - verified July 2016


Placebo-Controlled Study to Investigate the Efficacy & Safety of Injectafer in the Treatment of RLS


Condition:   Restless Legs Syndrome (RLS)
Interventions:   Drug: Injectafer;   Other: Placebo
Sponsor:   Luitpold Pharmaceuticals
Active, not recruiting - verified March 2017


Blinded, Randomized Study of Gabapentin (Neurontin®) and Gabapentin Enacarbil (Horizant™) in Restless Leg Syndrome


Condition:   Restless Leg Syndrome
Interventions:   Drug: Gabapentin immediate release;   Drug: Gabapentin enacarbil extended release
Sponsor:   Theresa Zesiewicz
Terminated - verified June 2016


Autonomic Function and Cardiovascular Risk in Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Interventions:   Drug: Pramipexole;   Drug: Placebo
Sponsors:   Mauro Manconi;   University Hospital Inselspital, Berne;   Cardiocentro Ticino
Completed - verified January 2017


Post-marketing Study of Gabapentin Enacarbil to Evaluate the Effect in Restless Leg Syndrome (RLS) Patients With Moderate Renal Impairment


Condition:   Restless Legs Syndrome (RLS)
Intervention:   Drug: Gabapentin enacarbil
Sponsor:   Astellas Pharma Inc
Completed - verified February 2017


Glutamate, Hyperarousal and Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Intervention:  
Sponsors:   Johns Hopkins University;   National Institutes of Health (NIH)
Completed - verified February 2017


Safety and Efficacy Study of IPX159 in Restless Legs Syndrome (RLS)


Condition:   Restless Legs Syndrome
Interventions:   Drug: IPX159;   Drug: Placebo
Sponsor:   IMPAX Laboratories, Inc.
Completed - verified January 2017


Long-Term Follow-Up Study for Safety, Efficacy and Tolerability of Rotigotine in Adolescents With Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Intervention:   Drug: Rotigotine
Sponsor:   UCB BIOSCIENCES, Inc.
Completed - verified October 2016


Efficacy of Tyrosine in Restless Legs Syndrome


Condition:   Restless Legs Syndrome (RLS)
Intervention:   Dietary Supplement: L-Tyrosine
Sponsor:   Seton Healthcare Family
Completed - verified April 2017


Clinical Evaluation of Ropinirole IR (Immediate Release) Tablets in Patients Who Are Diagnosed With Symptomatic Restless Legs Syndrome (RLS) Associated With Chronic Kidney Disease (CKD) Managed With Haemodialysis (Including Haemofiltration and Haemodiafiltration)


Condition:   Restless Legs Syndrome
Interventions:   Drug: Ropinirole immediate release (IR);   Drug: Placebo
Sponsor:   GlaxoSmithKline
Terminated - verified November 2016


Intravenous Iron Metabolism in Restless Legs Syndrome


Condition:   Restless Legs
Interventions:   Drug: Ferric Carboxymaltose (FCM);   Drug: Placebo
Sponsors:   Luitpold Pharmaceuticals;   National Institute on Aging (NIA)
Completed - verified May 2017


Clinical Evaluation of Ropinirole CR-RLS ( SK&F101468)Tablets in Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Intervention:   Drug: ropinirole controlled release (CR)-RLS
Sponsor:   GlaxoSmithKline
Completed - verified January 2017


12-week Polysomnography Study of Ropinirole Controlled Release for Restless Legs Syndrome


Conditions:   Restless Legs Syndrome (RLS);   Restless Legs Syndrome
Intervention:   Drug: ropinirole CR-RLS
Sponsor:   GlaxoSmithKline
Completed - verified October 2016


A Clinical Research Study Testing Ropinirole Treatment for Restless Legs Syndrome


Conditions:   Restless Legs Syndrome (RLS);   Restless Legs Syndrome
Intervention:   Drug: Ropinirole
Sponsor:   GlaxoSmithKline
Completed - verified October 2016


Long-Term Safety Of Ropinirole XR In Patients With Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Intervention:   Drug: Ropinirole Extended Release (XR)
Sponsor:   GlaxoSmithKline
Completed - verified October 2016


Long-term Study Of Ropinirole In Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Interventions:   Drug: Placebo;   Drug: Ropinirole
Sponsor:   GlaxoSmithKline
Completed - verified March 2017


RLS In Adults: Comparing Immediate Release Formulation With Extended Release Formulation Of Ropinirole


Conditions:   Restless Legs Syndrome;   Restless Legs Syndrome (RLS)
Intervention:   Drug: ropinirole Extended Release (XR)
Sponsor:   GlaxoSmithKline
Completed - verified October 2016


Converting From Ropinirole Immediate Release (IR) To Ropinirole Controlled-Release for RLS (Restless Legs Syndrome)


Conditions:   Restless Legs Syndrome;   Restless Legs Syndrome (RLS)
Intervention:   Drug: ropinirole controlled-release for RLS
Sponsor:   GlaxoSmithKline
Completed - verified September 2016


Ropinirole XR (Extended Release) In Patients With Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Intervention:   Drug: Ropinirole Extended Release (XR)
Sponsor:   GlaxoSmithKline
Completed - verified September 2016


A Clinical Research Study Evaluating Ropinirole Treatment For Restless Legs Syndrome (RLS)


Condition:   Restless Legs Syndrome
Intervention:   Drug: ropinirole
Sponsor:   GlaxoSmithKline
Completed - verified September 2016


Relationship Between Sensory and Motor Systems in Restless Leg Syndrome


Condition:   Restless Legs Syndrome
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified April 14, 2009


Effect of Ropinirole on Spinal Cord Reflexes and Restless Legs Syndrome


Condition:   Restless Legs Syndrome
Intervention:  
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Completed - verified October 18, 2007

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