Rem Sleep Disorder

Detecting Parkinson's Disease Through Speech Analysis

Conditions:   Parkinson Disease;   REM Sleep Behavior Disorder
Interventions:   Other: Speech assessment;   Other: Routine clinical assessment
Sponsors:   Czech Technical University in Prague;   General University Hospital, Prague;   University Hospital, Montpellier;   Mayo Clinic;   McGill University Health Center;   Medical University Innsbruck;   San Raffaele University Hospital, Italy;   Philipps University Marburg Medical Center
Recruiting - verified April 2017

Brain Imaging in the Idiopathic REM Sleep Behavior Disorder (ALICE)

Conditions:   REM Sleep Behavior Disorder;   Healthy
Intervention:   Other: Clinical investigations
Sponsors:   Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil;   NRJ Foundation - Institute of France;   National Research Agency, France
Completed - verified March 2017

Exploration of the Mechanism of Movement Improvement During RBD in Parkinson's Disease Using NIRS

Condition:   Parkinson Disease
Intervention:   Other: Near Infrared Spectroscopy
Sponsors:   Clinique Beau Soleil;   Université Montpellier
Recruiting - verified February 2017

Evolution of RBD in PD

Conditions:   REM Sleep Behavior Disorder;   Parkinson's Disease
Intervention:   Procedure: Video polysomnography
Sponsor:   University Hospital, Clermont-Ferrand
Not yet recruiting - verified February 2017

Prospective Neuroimaging Investigation of Idiopathic REM Sleep Behavior Disorder

Conditions:   Parkinson Disease;   REM Sleep Behavior Disorder
Intervention:   Other: testing, evaluation, sampling
Sponsors:   Seoul National University Hospital;   SMG-SNU Boramae Medical Center
Recruiting - verified February 2017

Open-label Study of Nelotanserin in Lewy Body Dementia With Visual Hallucinations or REM Sleep Behavior Disorder

Conditions:   Lewy Body Dementia;   Dementia With Lewy Bodies;   Parkinson's Disease Dementia;   Visual Hallucinations;   REM Sleep Behavior Disorder
Intervention:   Drug: Nelotanserin
Sponsor:   Axovant Sciences Ltd.
Enrolling by invitation - verified February 2017

Effect of Slow-release Melatonin (Circadin®) Therapy on Idiopathic RBD: a Pilot Study

Condition:   REM Sleep Behavior Disorder
Interventions:   Drug: Circadin;   Drug: Placebo
Sponsor:   Seoul National University Hospital
Recruiting - verified April 2017

Exploration of the Reward System by Functional MRI in Parkinson's Disease Patients With and Without REM Sleep Behavior Disorder

Conditions:   Parkinson's Disease;   REM Sleep Behavior Disorder
Intervention:   Device: fMRI
Sponsors:   University Hospital, Clermont-Ferrand;   Neurodis Foundation
Recruiting - verified July 2016

Efficacy and Safety of Melatonin PR and Clonazepam in Patients With REM Sleep Behavior Disorder in Parkinson Disease

Conditions:   REM Sleep Behavior Disorder;   Parkinson Disease
Interventions:   Drug: Melatonin PR;   Drug: Clonazepam;   Drug: Melatonin PR placebo;   Drug: Clonazepam placebo
Sponsors:   Seoul National University Hospital;   Kuhnil Pharmaceutical Co., Ltd.
Not yet recruiting - verified June 2016

Study Evaluating Nelotanserin for Treatment of REM Sleep Behavior Disorder in Subjects With Dementia (DLB or PDD)

Conditions:   Dementia With Lewy Bodies;   REM Sleep Behavior Disorder;   Parkinson's Disease Dementia
Interventions:   Drug: Nelotanserin;   Drug: Placebo
Sponsor:   Axovant Sciences Ltd.
Recruiting - verified March 2017

Retinal Abnormalities as Biomarker of Disease Progression and Early Diagnosis of Parkinson Disease

Conditions:   Parkinson Disease;   Multiple System Atrophy;   REM Sleep Behavior Disorder;   Pure Autonomic Failure;   Dementia With Lewy Bodies
Sponsors:   New York University School of Medicine;   Michael J. Fox Foundation for Parkinson's Research
Recruiting - verified August 2016

Motor Control During Rapid Eye Movement (REM) Sleep Behaviour Disorder

Condition:   Parkinson Disease
Intervention:   Other: Synchronised video-polysomnography
Sponsors:   University Hospital, Toulouse;   Grenoble Institut des Neurosciences
Terminated - verified February 2017

MRI Study of Brain Activity in Healthy Adults and Individuals With Parkinsonism and Rapid Eye Movement Disorder.

Conditions:   Movement Disorders (Incl Parkinsonism);   Tremor Familial Essential, 1;   REM Sleep Behavior Disorder
Sponsor:   University of Alabama at Birmingham
Completed - verified April 2017

DaTSCAN Imaging in Aging and Neurodegenerative Disease

Conditions:   Dementia;   Parkinsonism;   Mild Cognitive Impairment;   REM Sleep Behavior Disorder
Interventions:   Drug: I-123 Ioflupane solution injection prior to SPECT scan (DaTscan);   Device: Single photon emission computed tomography (SPECT) scan
Sponsor:   Mayo Clinic
Enrolling by invitation - verified March 2017

RBD Longitudinal as Prognostic for PD

Condition:   Rapid Eye Movement Sleep Behavior Disorder
Sponsor:   The University of Texas Health Science Center, Houston
Recruiting - verified September 2016

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