Cosmetic Procedures

About Cosmetic Procedures Clinical Trials (Click to Open)

Join Clinical Trials for Cosmetic Procedures

Cosmetic Procedures

General Purpose:

Many people at some point in their life decide to pursue a cosmetic procedure. For some, it is a choice made out of a desire to improve their appearance. For others, it may be perceived as a means of improving their self-esteem. Others may elect to undergo a cosmetic procedure out of necessity, following an injury that leads to disfigurement.

Fortunately, there are a wide variety of cosmetic procedures available that can help improve the appearance of almost any part of the body.

Examples include liposuction, implants (facial, breasts, calves, buttocks), treatments for spider veins, hair replacement procedures, hair removal procedures, breast reduction procedures, nose surgery, body contouring surgery, and tummy tucks, just to name a few. Collectively, these procedures are often referred to as “plastic surgery.”

Research related to many different aspects of plastic surgery is currently ongoing. In addition to investigating more advanced and less-invasive techniques, scientists are also conducting research to learn how to minimize the side effects of various surgical interventions, as well as evaluating the psychological impact such procedures have on those who receive them.

What Will A Cosmetic Procedures Clinical Trial Be Like? 

Due to the wide variety of cosmetic procedures available, clinical trials will likely differ substantially with regard to the procedures involved, the information they obtain from participants, and their overall objective. Provided below is a list of common procedures, tests, and assessments that may be incorporated into such clinical trials, but please note that studies are likely to differ across a wide variety of aspects:

  • Detailed physical examination
  • Photographs to document before-and-after progress of a particular procedure Topical prescription medications that contain derivatives of vitamin A
  • Surgical procedures involving either local (site-specific) or general anesthesia
  • You may be asked to complete a questionnaire to determine how much of an impact your cosmetic procedure has on your emotional-well being, self-confidence, and self-esteem.
  • Dietary interventions
  • Exercise interventions

Typical Cosmetic Procedure Clinical Trial Protocol:

Specific examples of clinical trials for various cosmetic procedures might include the following:

  • A study designed to evaluate the quality of life and body image of women who undergo thighplasty (a surgical procedure to improve the contour of the thighs and buttocks) following bariatric surgery for obesity.
  • A study designed to determine the long-term health effects of breast augmentation using silicone gel breast implants.
  • A study to determine the safety and efficacy of a new surgical approach to performing a tummy tuck procedure. Men and women undergoing this procedure will be randomly assigned to receive the surgery using the standard technique, or to receive the new surgical approach.
  • A study designed to compare the effectiveness of two separate pain medications in burn patients undergoing skin-graft surgery.


The type of clinical trial you may be eligible for often depends on many factors. Therefore, it is important to know as many details as possible with regard to your specific circumstances when searching for clinical trials.  Examples of information you may want to have on hand include the following:

  • The type of cosmetic procedure you are interested in
  • Your prior and current diagnoses of any health conditions or diseases
  • Your current medications (including vitamins, minerals, and other dietary supplements)

Suggested Search Terms:

Once you are ready to begin your search for cosmetic procedures related clinical trials, the following terms may be of use when combined with the particular cosmetic procedure you are seeking information about: “side effects,” “long term effects,” “complications,” and “alternatives.”


Current Search Term:

“Cosmetic Procedures”

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Determination of the Sun Protection Factor (SPF) of a Cosmetic Daily De-fence Skin Cream

Condition:   Sunscreening Agents
Interventions:   Other: Physiogel Daily Defence Protective Day Cream Light;   Other: ISO 24444:2010 P3 Standard Sunscreen
Sponsor:   GlaxoSmithKline
Not yet recruiting - verified April 2017

Comparison of Clinical Performance and Subjective Preference Out of Three Cosmetic Contact Lenses (Limbal Ring-enhancing Lenses, LRE Lenses)

Condition:   Myopia
Interventions:   Device: etafilcon A;   Device: methafilcon A - Interozzo;   Device: methafilcon A - CVI (CooperVision)
Sponsor:   Coopervision, Inc.
Recruiting - verified April 2017

To Assess the Mildness of a Cosmetic Cleanser in Healthy Participants Using the Forearm-Controlled Application Technique (FCAT)

Condition:   Skin Care
Interventions:   Other: Test Product;   Other: Positive Control;   Other: Reference Product
Sponsor:   GlaxoSmithKline
Recruiting - verified May 2017

The Oncological Safety and Cosmetic Outcome of Areola Sparing Mastectomy : a Single Arm, Prospective, Cohort Study

Condition:   Breast Neoplasms
Intervention:   Procedure: Areola Sparing Mastectomy
Sponsor:   Peking University People's Hospital
Not yet recruiting - verified April 2017

Comparison of the Cosmetic Effects of Bakuchiol and Retinol

Conditions:   Wrinkle;   Photoaging
Interventions:   Drug: Bakuchiol;   Drug: Retinol
Sponsor:   University of California, Davis
Recruiting - verified April 2017

Investigation of the Cosmetic Benefit Provided by Regular Application of a Moisturising Cream in People With Blemish Prone Skin

Condition:   Skin Care
Interventions:   Other: Washout / Standard Cleanser;   Other: Test product;   Other: Positive control cleanser;   Other: Positive control moisturiser
Sponsor:   GlaxoSmithKline
Not yet recruiting - verified March 2017

Evaluation of the Cosmetic Benefit of a Skin Cream in Healthy Females With Mild to Advanced Photo-damaged Facial Skin Who Have Undergone a Glycolic Acid Facial Peel Procedure

Condition:   Skin Care
Interventions:   Other: Cream (Test product);   Other: Cleanser (Reference Product);   Other: Sunscreen (Reference Product)
Sponsor:   GlaxoSmithKline
Recruiting - verified May 2017

Purse String Suture for the Closure of Large Thyroidectomy Resulted in Better Cosmetics

Condition:   Thyroidectomy
Interventions:   Procedure: Purse string technique;   Procedure: Conventional technique
Sponsor:   Dr Cipto Mangunkusumo General Hospital
Completed - verified January 2017

Epicutaneous Testing of Cosmetics

Condition:   Dermatitis
Intervention:   Other: Patch test application
Sponsors:   University Hospital Inselspital, Berne;   Mibelle AG
Recruiting - verified May 2017

Volumetric Study of Fat Resorption After Breast Lipofilling

Conditions:   Cosmetic Techniques;   Mammaplasty
Intervention:   Procedure: Technique of Breast Lipofilling
Sponsor:   University of Malaya
Completed - verified January 2017

Split-face Study Comparing the Cosmetic Efficacy and Tolerability of Two Topical Products in Subjects With Moderate Facial Melasma

Condition:   Melasma
Interventions:   Other: Lytera 2.0;   Other: 4% Hydroquinone Topical Cream
Sponsor:   Allergan
Recruiting - verified December 2016

Effect of Anesthesia on Quality of Recovery in Patients Undergoing Cosmetic Lower Limb Lengthening - A Randomized Controlled Trial

Condition:   Short Stature
Interventions:   Drug: propofol and remifentanil;   Drug: desflurane and remifentanil
Sponsor:   Yonsei University
Recruiting - verified December 2016

Polyglactin 910 vs Poligelecaprone 25 Running Subcuticular Closure of Elliptical Excision Wounds

Condition:   Cosmetics, Suture, Cicatrix
Intervention:   Procedure: running subcuticular closure of excisional defect
Sponsor:   University of California, Los Angeles
Withdrawn - verified May 2017

Medipore Tape Study

Condition:   Scarring
Interventions:   Other: Standard Post Operative Skin Care;   Other: Medipore Tape
Sponsor:   New York University School of Medicine
Completed - verified August 2016

Comparison of Different Umbilical Port Entry Techniques in Terms of Cosmetic Results

Condition:   Cicatrix
Intervention:   Procedure: Ten mm trocar
Sponsor:   Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Recruiting - verified October 2016

Efficacy Study of a Cosmetic Lotion in the Treatment of Alopecia Areata in Males and Females

Condition:   Alopecia Areata
Intervention:   Other: MEXIS/M6S Patent - lotion against alopecia
Sponsor:   Mexis George
Recruiting - verified January 2017

Topical Acetyl Hexapeptide-8 and the Cosmetic Appearance of Oily Skin

Condition:   Oily Skin
Interventions:   Other: Acetyl Hexapeptide-8;   Other: Placebo vehicle
Sponsor:   University of California, Davis
Completed - verified March 2017

Curing Atopic Dermatits in Children With a Commerical Medical Device and Maintaining Healthy Skin by Using a New Cosmetic Product

Condition:   Dermatitis, Atopic
Interventions:   Device: Bepanthen Itch Relief Cream: Phoenix 2 (Bepanthen Sensiderm, BAY207543);   Other: New cosmetic Bepanthen product: Pumpkin (BAY207543);   Other: Stelatopia (cosmetic comparator)
Sponsor:   Bayer
Completed - verified November 2016

Comparative Study to Evaluate the Cosmetic Appearance of Two Brands (Coopervision (CVI) vs. Competitor) of Color Soft Contact Lenses.

Condition:   Myopia
Interventions:   Device: Verde (Competitor-control);   Device: Green (CVI-test);   Device: Cinza (Competitor-control);   Device: Grey (CVI-test);   Device: Esmeralda (Competitor-control);   Device: Jade (CVI-test);   Device: Azul (Competitor-control);   Device: Blue (CVI-test)
Sponsor:   Coopervision, Inc.
Completed - verified January 2017

3D Breast Imaging for Cosmetic and Reconstructive Breast Surgery

Conditions:   Hypomastia;   Primary Breast Augmentation
Intervention:   Device: 3D Imaging
Sponsors:   Washington University School of Medicine;   Allergan
Active, not recruiting - verified October 2016

The Effect of the Cosmetic Cream NMBM on Leg Ulcers - a Pilot Study

Conditions:   Ulcer;   Venous Ulcer;   Skin Ulcer;   Leg Ulcer
Interventions:   Device: NMBM;   Other: Compression garments
Sponsor:   M.D. Lederman Consulting Ltd
Completed - verified June 2016

Cosmetic Result/Toxicity in Post-Mastectomy Immediate Reconstruction Expander+RT

Condition:   Breast Cancer
Intervention:   Radiation: Radiation Therapy
Sponsors:   Dana-Farber Cancer Institute;   Brigham and Women's Hospital
Active, not recruiting - verified December 2016

Nipple Sparing Mastectomy - Cosmetic Outcomes

Conditions:   Breast Cancer;   Breast Reconstruction;   Cosmesis
Intervention:   Procedure: Nipple Sparing Mastectomy
Sponsor:   Carolinas Healthcare System
Active, not recruiting - verified February 2017

Cosmetic Outcomes of Absorbable Versus Non-absorbable Sutures in Pediatric Facial Lacerations

Conditions:   Lacerations;   Wounds
Interventions:   Other: Arm 2: Absorbable sutures;   Other: Arm 1: non-absorbable sutures
Sponsor:   Temple University
Completed - verified February 2017

Study of Health Effects of Cosmetic Breast Augmentation

Conditions:   Brain Cancer;   Breast Cancer;   Lung Cancer;   Suicide
Sponsor:   National Cancer Institute (NCI)
Completed - verified April 17, 2017

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