Gonorrhea



New AntiBiotic Treatment Options for Uncomplicated Anogenital GOnorrhoea


Condition:   Gonorrhea
Interventions:   Drug: Ertapenem 1000 MG;   Drug: Fosfomycin Oral Suspension;   Drug: Gentamicin Sulfate, Injectable;   Drug: Ceftriaxone
Sponsors:   Public Health Service of Amsterdam;   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Recruiting


Online HIV Prevention for Young Male Couples


Conditions:   Hiv;   Chlamydia;   Gonorrhea
Interventions:   Behavioral: 2GETHER;   Behavioral: Existing Public Health Practice
Sponsor:   Northwestern University
Not yet recruiting


Trial to Assess the Efficacy of F598 in Preventing an Experimental Urethral Infection With N. Gonorrhoeae in Healthy Males


Condition:   Neisseria Gonorrhoeae
Interventions:   Drug: 1 mg/kg single infusion of F598;   Drug: 3 mg/kg single infusion of F598;   Drug: 10 mg/kg single infusion of F598
Sponsor:   Alopexx Pharmaceuticals, LLC
Not yet recruiting


Randomized Trial of an HIV Prevention and Relationship Education Program for Young Male Couples


Conditions:   Hiv;   Chlamydia;   Gonorrhea;   Relation, Interpersonal
Interventions:   Behavioral: 2GETHER;   Behavioral: Positive Affect Enhancement
Sponsors:   Northwestern University;   University of Cincinnati;   Howard Brown Health Center
Not yet recruiting


Use of a Rapid Turnaround Test for NG/CT to Improve Treatment of Women Presenting With Possible STIs


Conditions:   Sexually Transmitted Infection;   Gonorrhea Female;   Chlamydia Females
Interventions:   Device: Cepheid Xpert CT/NG Rapid Turnaround Test;   Device: Polymerase chain reaction (PCR)
Sponsor:   University of Maryland
Not yet recruiting


Check it: A New Approach to Controlling Chlamydia Transmission in Young People


Conditions:   Chlamydia Trachomatis Infection;   Gonorrhea
Intervention:   Other: Ct/GC screening
Sponsors:   Tulane University;   National Institutes of Health (NIH);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting


Screening of Gonococcal and Chlamydial Infections in the Third Trimester


Conditions:   Gonococcal Infection;   Chlamydia Infections
Intervention:  
Sponsor:   St. Michael's Hospital, Toronto
Enrolling by invitation


Evaluation of the Atlas Genetics io® CTNG System


Conditions:   Chlamydia Trachomatis;   Gonorrhea
Intervention:   Device: Atlas Genetics io® system
Sponsor:   Atlas Genetics Limited
Recruiting


STI Screening as a Combined HIV Prevention Platform for MSM in Peru


Conditions:   Gonorrhoea of Rectum;   Chlamydia of Rectum;   HIV Infections
Interventions:   Behavioral: PCC;   Behavioral: Traditional Counseling
Sponsors:   University of California, Los Angeles;   NGO Via Libre;   University of California, San Francisco
Recruiting


Clinical Validation of a Molecular Test for Ciprofloxacin-Susceptibility in Neisseria Gonorrheaoe


Condition:   Gonorrhoea
Intervention:   Drug: Ciprofloxacin
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting


Performance of Nucleic Acid Amplification Tests for the Detection of NG and CT


Conditions:   Neisseria Gonorrhoeae Infection;   Chlamydia Trachomatis Infection;   Sexually Transmitted Diseases
Interventions:   Device: NAAT 1 to Detect Rectal and Pharyngeal NG and CT;   Device: NAAT 2 to Detect Rectal and Pharyngeal NG and CT;   Device: NAAT 3 to Detect Rectal and Pharyngeal NG and CT;   Device: NAAT 4 to Detect Rectal and Pharyngeal NG;   Device: NAAT 4 to Detect Rectal and Pharyngeal CT
Sponsors:   Duke University;   National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting


Clinical Evaluation of the Aptima® Combo 2® Assay Using the Panther® System in Female Urine Samples


Conditions:   Chlamydia Trachomatis;   Gonorrhea
Intervention:  
Sponsor:   Hologic, Inc.
Terminated


Cefixime / Azithromycin pK Study


Condition:   Gonorrhoea
Interventions:   Drug: Azithromycin;   Drug: Cefixime
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Completed


Trial of an Adapted STD Screening and Risk Reduction Intervention


Conditions:   Alcohol Use;   Drug Use;   Diagnostic Self Evaluation;   Gonorrhea;   Unprotected Sex;   Chlamydia;   Trichomonas
Interventions:   Behavioral: Project EMPWR;   Other: Optimized Standard Care (OSC)
Sponsor:   Johns Hopkins Bloomberg School of Public Health
Recruiting


Texting Intervention to Sustain HIV Prevention in Women in High-drug-use Contexts


Conditions:   HIV;   Syphilis;   Gonorrhea;   Chlamydia
Interventions:   Behavioral: Mujer Segura Siempre;   Behavioral: General Health Message Texts
Sponsors:   University of California, San Diego;   Comisión de Salud Fronteriza México-Estados Unidos (CSFMEU)
Active, not recruiting


Multimedia WORTH With Black Drug-Involved Women on Probation


Conditions:   Sexually Transmitted Infections;   HIV;   Gonorrhea;   Trichomonas;   Chlamydia Trachomatis;   Drug Use
Interventions:   Behavioral: E-WORTH;   Behavioral: Streamlined HIV Testing
Sponsors:   Columbia University;   Fortune Society;   University of Pennsylvania;   State University of New York - Downstate Medical Center;   RTI International;   Duke University;   National Institute on Drug Abuse (NIDA)
Recruiting


Genitourinary and Pharyngeal Pharmacokinetics of Solithromycin


Condition:   Gonorrhoea
Intervention:   Drug: Solithromycin
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Completed



Randomized, Open-label Phase 2 Study of Oral AZD0914 in the Treatment of Gonorrhea


Condition:   Gonorrhoea
Interventions:   Drug: AZD0914;   Drug: Ceftriaxone
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)
Completed


Efficacy and Safety Study of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin in the Treatment of Patients With Gonorrhea


Condition:   Uncomplicated Urogenital Gonorrhea
Interventions:   Drug: solithromycin;   Drug: ceftriaxone;   Drug: azithromycin
Sponsors:   Cempra Inc;   National Institute of Allergy and Infectious Diseases (NIAID)
Completed


Gonorrhea and Chlamydia HIV-infected Men Who Have Sex With Men


Conditions:   HIV Infection;   Chlamydia;   Gonorrhea
Intervention:  
Sponsor:   University of Nebraska
Completed


Keep It Up! 2.0: A Comparison of Two Online HIV Intervention Programs for Young Men Who Have Sex With Men


Conditions:   HIV;   Gonorrhea;   Chlamydia
Interventions:   Behavioral: Keep It Up!;   Behavioral: HIV Knowledge Control
Sponsors:   Northwestern University;   National Institute on Drug Abuse (NIDA);   Emory University;   Hunter College of City University of New York
Completed


Prospective Collection of Female Specimens for Testing With Gen-Probe APTIMA (Registered Trademark) Assays


Conditions:   Chlamydia Infections;   Gonorrhea;   Trichomonas Infections
Intervention:   Device: APTIMA® Trichomonas vaginalis & APTIMA® COMBO 2® Assays
Sponsor:   Gen-Probe, Incorporated
Terminated


Safety and Efficacy Study of Single-Dose Oral CEM-101 in Patients With Uncomplicated Urogenital Gonorrhea


Condition:   Uncomplicated Urogenital Gonorrhea
Interventions:   Drug: solithromycin;   Drug: Solithromycin (CEM-101)
Sponsor:   Cempra Inc
Completed


Safety and Acceptability of Carraguard™ Among HIV-negative Couples in Thailand


Conditions:   HIV Infections;   Chlamydia Trachomatis;   Nesseria Gonorrhea;   Trichomonas Vaginitis;   Syphilis
Intervention:   Drug: Carraguard (PC-515)
Sponsors:   Population Council;   Centers for Disease Control and Prevention;   Ministry of Health, Thailand;   Chiang Rai Public Health Office;   Chiang Rai District Health Office;   Chiang Rai Municipal Health Office;   Chiang Rai Hospital;   Bill and Melinda Gates Foundation
Completed

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