A Study to Evaluate the Safety, Tolerability and Plasma PK of a Single Oral Dose of Zoliflodacin in Healthy Male and Female Volunteers

Condition:   Gonorrhoea
Intervention:   Drug: AZD0914
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)

New AntiBiotic Treatment Options for Uncomplicated Anogenital GOnorrhoea

Condition:   Gonorrhea
Interventions:   Drug: Ertapenem 1000 MG;   Drug: Fosfomycin Oral Suspension;   Drug: Gentamicin Sulfate, Injectable;   Drug: Ceftriaxone
Sponsors:   Public Health Service of Amsterdam;   Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Online HIV Prevention for Young Male Couples

Conditions:   Hiv;   Chlamydia;   Gonorrhea
Interventions:   Behavioral: 2GETHER;   Behavioral: Existing Public Health Practice
Sponsor:   Northwestern University
Not yet recruiting

Trial to Assess the Efficacy of F598 in Preventing an Experimental Urethral Infection With N. Gonorrhoeae in Healthy Males

Condition:   Neisseria Gonorrhoeae
Interventions:   Drug: 1 mg/kg single infusion of F598;   Drug: 3 mg/kg single infusion of F598;   Drug: 10 mg/kg single infusion of F598
Sponsor:   Alopexx Pharmaceuticals, LLC

Randomized Trial of an HIV Prevention and Relationship Education Program for Young Male Couples

Conditions:   Hiv;   Chlamydia;   Gonorrhea;   Relation, Interpersonal
Interventions:   Behavioral: 2GETHER;   Behavioral: Positive Affect Enhancement
Sponsors:   Northwestern University;   University of Cincinnati;   Howard Brown Health Center
Not yet recruiting

Use of a Rapid Turnaround Test for NG/CT to Improve Treatment of Women Presenting With Possible STIs

Conditions:   Sexually Transmitted Infection;   Gonorrhea Female;   Chlamydia Females
Interventions:   Device: Cepheid Xpert CT/NG Rapid Turnaround Test;   Device: Polymerase chain reaction (PCR)
Sponsor:   University of Maryland
Not yet recruiting

Check it: A New Approach to Controlling Chlamydia Transmission in Young People

Conditions:   Chlamydia Trachomatis Infection;   Gonorrhea
Intervention:   Other: Ct/GC screening
Sponsors:   Tulane University;   National Institutes of Health (NIH);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

MAMAS: Mentoring Adolescent Mothers at School

Conditions:   Human Immunodeficiency Virus;   Herpes Simplex Type II;   Chlamydia;   Gonorrhea;   Trichomonas Vaginitis
Intervention:   Behavioral: Mentoring Adolescent Mothers at School (MAMAS)
Sponsors:   Drexel University;   University of KwaZulu;   University of North Carolina, Chapel Hill

Evaluation of the Atlas Genetics io® CTNG System

Conditions:   Chlamydia Trachomatis;   Gonorrhea
Intervention:   Device: Atlas Genetics io® system
Sponsor:   Atlas Genetics Limited

STI Screening as a Combined HIV Prevention Platform for MSM in Peru

Conditions:   Gonorrhoea of Rectum;   Chlamydia of Rectum;   HIV Infections
Interventions:   Behavioral: PCC;   Behavioral: Traditional Counseling
Sponsors:   University of California, Los Angeles;   NGO Via Libre;   University of California, San Francisco
Active, not recruiting

Clinical Validation of a Molecular Test for Ciprofloxacin-Susceptibility in Neisseria Gonorrheaoe

Condition:   Gonorrhoea
Intervention:   Drug: Ciprofloxacin
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)

Performance of Nucleic Acid Amplification Tests for the Detection of NG and CT

Conditions:   Neisseria Gonorrhoeae Infection;   Chlamydia Trachomatis Infection;   Sexually Transmitted Diseases
Interventions:   Device: NAAT 1 to Detect Rectal and Pharyngeal NG and CT;   Device: NAAT 2 to Detect Rectal and Pharyngeal NG and CT;   Device: NAAT 3 to Detect Rectal and Pharyngeal NG and CT;   Device: NAAT 4 to Detect Rectal and Pharyngeal NG;   Device: NAAT 4 to Detect Rectal and Pharyngeal CT
Sponsors:   Duke University;   National Institute of Allergy and Infectious Diseases (NIAID)

Cefixime / Azithromycin pK Study

Condition:   Gonorrhoea
Interventions:   Drug: Azithromycin;   Drug: Cefixime
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)

Trial of an Adapted STD Screening and Risk Reduction Intervention

Conditions:   Alcohol Use;   Drug Use;   Diagnostic Self Evaluation;   Gonorrhea;   Unprotected Sex;   Chlamydia;   Trichomonas
Interventions:   Behavioral: Project EMPWR;   Other: Optimized Standard Care (OSC)
Sponsor:   Johns Hopkins Bloomberg School of Public Health

Texting Intervention to Sustain HIV Prevention in Women in High-drug-use Contexts

Conditions:   HIV;   Syphilis;   Gonorrhea;   Chlamydia
Interventions:   Behavioral: Mujer Segura Siempre;   Behavioral: General Health Message Texts
Sponsors:   University of California, San Diego;   Comisión de Salud Fronteriza México-Estados Unidos (CSFMEU)
Active, not recruiting

Efficacy and Safety Study of Oral Solithromycin Compared to Intramuscular Ceftriaxone Plus Oral Azithromycin in the Treatment of Patients With Gonorrhea

Condition:   Uncomplicated Urogenital Gonorrhea
Interventions:   Drug: solithromycin;   Drug: ceftriaxone;   Drug: azithromycin
Sponsors:   Cempra Inc;   National Institute of Allergy and Infectious Diseases (NIAID)

Cepheid Rectal Sample Validation Study

Conditions:   Gonorrhea;   Chlamydia;   Trichomonas
Intervention:   Device: STD testing (GC/Ct/trich)
Sponsors:   University of Pittsburgh;   National Institute of Allergy and Infectious Diseases (NIAID)

Detection of Chlamydia (CT) and Gonorrhea (NG)

Conditions:   Chlamydia;   Gonorrhea
Intervention:   Device: illumigene CT and NG assays, illumipro-10
Sponsor:   Meridian Bioscience, Inc.

Gonorrhea and Chlamydia HIV-infected Men Who Have Sex With Men

Conditions:   HIV Infection;   Chlamydia;   Gonorrhea
Sponsor:   University of Nebraska

Keep It Up! 2.0: A Comparison of Two Online HIV Intervention Programs for Young Men Who Have Sex With Men

Conditions:   HIV;   Gonorrhea;   Chlamydia
Interventions:   Behavioral: Keep It Up!;   Behavioral: HIV Knowledge Control
Sponsors:   Northwestern University;   National Institute on Drug Abuse (NIDA);   Emory University;   Hunter College of City University of New York

Prospective Collection of Female Specimens for Testing With Gen-Probe APTIMA (Registered Trademark) Assays

Conditions:   Chlamydia Infections;   Gonorrhea;   Trichomonas Infections
Intervention:   Device: APTIMA® Trichomonas vaginalis & APTIMA® COMBO 2® Assays
Sponsor:   Gen-Probe, Incorporated

Safer Sex Program for Young African-American Men

Conditions:   Gonorrhea;   Chlamydia;   Trichomoniasis;   Syphilis;   HIV Infections
Intervention:   Behavioral: Intervention
Sponsors:   Richard Crosby;   National Institute of Mental Health (NIMH)

Safety and Acceptability of Carraguard™ Among HIV-negative Couples in Thailand

Conditions:   HIV Infections;   Chlamydia Trachomatis;   Nesseria Gonorrhea;   Trichomonas Vaginitis;   Syphilis
Intervention:   Drug: Carraguard (PC-515)
Sponsors:   Population Council;   Centers for Disease Control and Prevention;   Ministry of Health, Thailand;   Chiang Rai Public Health Office;   Chiang Rai District Health Office;   Chiang Rai Municipal Health Office;   Chiang Rai Hospital;   Bill and Melinda Gates Foundation

Safety, Acceptability and Preliminary Effectiveness of Carraguard™ (PC-515) in Preventing HIV/STI Transmission

Conditions:   HIV Infections;   Chlamydia Trachomatis;   Neisseria Gonorrhoeae;   Trichomonas Vaginitis;   Syphilis
Intervention:   Drug: Carraguard (PC-515)
Sponsors:   Population Council;   Bill and Melinda Gates Foundation;   FHI 360;   National Institute of Allergy and Infectious Diseases (NIAID);   Medical Research Council, South Africa;   University of Cape Town;   University of Limpopo;   United States Agency for International Development (USAID)

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