Pediatric Ear Infections



The Efficacy of Nasal Steroids in Treatment of Otitis Media With Effusion: Acomparative Study


Condition:   Otitis Media With Effusion
Interventions:   Drug: Mometasone Furoate spray;   Drug: prednisolone sodium phosphate 15mg;   Drug: hypertonic sea water solution spray
Sponsor:   Muteea Mubark Salmen Bakuwiri
Not yet recruiting


The Microbiome Variability and Antibiotic Resistance of Chronic Suppurative Otitis


Condition:   Suppurative Otitis Media
Intervention:  
Sponsor:   Ziv Hospital
Not yet recruiting


Taste Changes in Acute Otitis Media


Condition:   Acute Otitis Media
Intervention:   Diagnostic Test: Electrogustometery
Sponsors:   Tel-Aviv Sourasky Medical Center;   Tel Aviv University
Not yet recruiting


Efficacy and Safety of DF289 Plus DF277 Otic Solution in the Treatment of Acute Otitis Externa


Condition:   Acute Otitis Externa
Interventions:   Drug: DF289 plus DF277;   Drug: DF289;   Drug: DF277
Sponsor:   Salvat
Recruiting


E-learning on the Trainees' Ability to Diagnose and Treat Acute Otitis Media Among Children


Condition:   Ear Infection
Interventions:   Other: e-learning teaching module;   Other: Standard teaching method
Sponsor:   St. Justine's Hospital
Recruiting


Xylitol for Otitis Media


Condition:   Otitis Media With Effusion
Interventions:   Drug: Intranasal xylitol spray;   Other: Intranasal saline spray
Sponsor:   Duke University
Withdrawn


Effect of Antimicrobial Treatment of Acute Otitis Media on the Intestinal Microbiome in Children


Condition:   Acute Otitis Media
Interventions:   Drug: Amoxicillin;   Drug: Amoxicillin-Potassium Clavulanate;   Drug: Macrolide
Sponsors:   University of Oulu;   Oulu University Hospital
Recruiting


Shared Decision Making in Parents of Children With Acute Otitis Media


Condition:   Acute Otitis Media
Interventions:   Other: Acute Otitis Media Choice Decision Aid;   Other: Usual Care
Sponsor:   Mayo Clinic
Recruiting


A Clinical Trial of YH1177 in Patients With Otitis Media and Otorrhea


Conditions:   Otitis Media;   Otorrhea
Interventions:   Drug: piperacillin 4% + tazobactam 0.5% + dexamethasone 0.1%;   Drug: piperacillin 8% + tazobactam 1.0% + dexamethasone 0.1%;   Drug: piperacillin 2% + tazobactam 0.25%;   Drug: piperacillin 4% + tazobactam 0.5%;   Drug: piperacillin 8% + tazobactam 1.0%
Sponsor:   Yuhan Corporation
Active, not recruiting


Phase 3 Study of OTO-201 in Acute Otitis Externa


Conditions:   Acute Otitis Externa;   Swimmer's Ear
Interventions:   Drug: 12 mg ciprofloxacin;   Drug: Sham Control
Sponsor:   Otonomy, Inc.
Completed


Video Discharge Instructions for Acute Otitis Media


Condition:   Otitis Media
Interventions:   Other: Video discharge instructions;   Other: Standard of Care
Sponsor:   Lawson Health Research Institute
Recruiting


Impact of Pneumococcal Conjugate Vaccines on Otitis Media and Acute Otitis Media in Swedish Children


Conditions:   Acute Otitis Media;   Otitis Media
Intervention:   Other: Data collection
Sponsor:   GlaxoSmithKline
Completed


Reduced Clavulanate Formulation of Amoxicillin-Clavulanate in Children 6-23 Months With Acute Otitis Media


Condition:   Acute Otitis Media
Intervention:   Drug: Amoxicillin-Clavulanate potassium
Sponsor:   Nader Shaikh
Completed


Efficacy of Tympanostomy Tubes for Children With Recurrent Acute Otitis Media


Condition:   Acute Otitis Media
Interventions:   Procedure: Tympanostomy tube placement;   Procedure: Nonsurgical management
Sponsors:   University of Pittsburgh;   George Washington University;   National Institute on Deafness and Other Communication Disorders (NIDCD)
Recruiting


Safety and Efficacy of EXE844 Otic Suspension in Otitis Media at Time of Tympanostomy Tube Insertion (OMTT) - Study 2


Conditions:   Otitis Media With Effusion in Children;   Otitis Media Recurrent
Interventions:   Drug: EXE844 Sterile Otic Suspension, 0.3%;   Procedure: Tympanostomy Tube Insertion
Sponsor:   Alcon Research
Completed


Safety and Efficacy of EXE844 Otic Suspension in Otitis Media at Time of Tympanostomy Tube Insertion (OMTT)


Conditions:   Otitis Media With Effusion in Children;   Otitis Media Recurrent
Interventions:   Drug: EXE844 Sterile Otic Suspension, 0.3%;   Procedure: Tympanostomy Tube Insertion
Sponsor:   Alcon Research
Completed


Bioequivalence of Two Ciprofloxacin 0.3%/Dexamethasone 0.1% Sterile Otic Suspensions in Otitis Media in Children With Tympanostomy Tubes


Condition:   Otitis Media in Patients With Tympanostomy Tubes
Interventions:   Drug: Ciprofloxacin 0.3%/dexamethasone 0.1% sterile otic suspension;   Drug: CIPRODEX® (ciprofloxacin 0.3%/dexamethasone 0.1%);   Drug: Placebo Sterile Otic Suspension
Sponsors:   Par Pharmaceutical, Inc.;   Novum Pharmaceutical Research Services
Terminated


Proof-of-Concept Study of a Single Application of an Investigational Otic Suspension in Treatment of Acute Otitis Media With Tympanostomy Tubes


Condition:   Acute Otitis Media
Interventions:   Drug: AL-60371/AL-817 otic suspension;   Drug: Ciprofloxacin 0.3%/dexamethasone 0.1% otic suspension
Sponsor:   Alcon Research
Terminated


Efficacy of Short-Course Antimicrobial Treatment for Children With Acute Otitis Media and Impact on Resistance


Condition:   Acute Otitis Media
Interventions:   Drug: Amoxicillin-Clavulanate, 10 days;   Drug: Amoxicillin-Clavulanate, 5 days
Sponsors:   Alejandro Hoberman;   National Institute of Allergy and Infectious Diseases (NIAID)
Terminated


Special Drug Use Investigation for CLAVAMOX® (Amoxicillin/Clavulanate) Pediatrics Dry Syrup (Every Indication Excluded Otitis Media)


Condition:   Otitis Maedia
Intervention:   Drug: Amoxicillin and clavulanate
Sponsor:   GlaxoSmithKline
Completed


Efficacy and Safety of DF289 Plus DF277 Otic Solution in the Treatment of Middle Ear Infections in Pediatric Patients


Condition:   Acute Otitis Media
Interventions:   Drug: DF289;   Drug: DF277;   Drug: DF289 plus DF277
Sponsor:   Salvat
Completed


Study to Identify and Characterize the Bacteria Causing Acute Otitis Media Episodes in Young Children in Taiwan


Condition:   Acute Otitis Media
Intervention:   Procedure: Sample Collection
Sponsor:   GlaxoSmithKline
Terminated


N-Acetylcysteine as an Adjunct for Refractory Chronic Suppurative Otitis Media


Conditions:   Otitis Media;   Otorrhea
Interventions:   Drug: Ciprodex;   Drug: Ciprodex and 2% NAC
Sponsor:   St. Paul's Hospital, Canada
Not yet recruiting


A Clinical Trial of Proton Pump Inhibitors to Treat Children With Chronic Otitis Media With Effusion


Condition:   Otitis Media With Effusion
Interventions:   Drug: lansoprazole;   Drug: placebo
Sponsors:   Washington University School of Medicine;   Doris Duke Charitable Foundation;   TAP Pharmaceutical Products Inc.
Completed


Osteopathic Otitis Media Research Study


Condition:   Otitis Media With Effusion
Intervention:   Procedure: osteopathic manipulative medicine (OMM)
Sponsors:   West Virginia School of Osteopathic Medicine;   University of New England;   American Academy of Osteopathy;   Osteopathic Research Center
Completed

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