Nerve Damage



Tesamorelin to Improve Functional Outcomes After Peripheral Nerve Injury


Condition:   Peripheral Nerve Injuries
Interventions:   Drug: Tesamorelin 2 Milligrams (MG);   Drug: Placebo
Sponsor:   Johns Hopkins University
Not yet recruiting - verified May 2017


Extracorporal Shock Wave Treatment to Improve Nerve Regeneration


Condition:   Peripheral Nerve Injury
Interventions:   Device: MTS Medical UG Orthogold 100;   Device: Sham
Sponsor:   Ludwig Boltzmann Gesellschaft
Recruiting - verified May 2017


Pain-related Evoked Potentials in Unilateral Peripheral Nerve Injuries


Condition:   Peripheral Nerve Injuries
Interventions:   Diagnostic Test: Pain-related evoked potentials (PREP);   Diagnostic Test: Quantitative Sensory Testing (QST);   Diagnostic Test: Nerve conduction studies (NCS)
Sponsor:   Ruhr University of Bochum
Completed - verified March 2017


Identification of Neuromas by High Resolution Ultrasound in Patients With Peripheral Nerve Injury and Amputations


Conditions:   Neuropathic Pain;   Neuroma
Intervention:  
Sponsor:   Danish Pain Research Center
Recruiting - verified February 2017


Neural Injury in Adolescents With Concussion


Conditions:   Mild Traumatic Brain Injury;   Concussion, Mild;   Acute Brain Injury
Interventions:   Device: MEG;   Device: MRI;   Behavioral: Neuropsychology assessment
Sponsor:   Children's Hospital of Philadelphia
Not yet recruiting - verified January 2017


A Phase I Trial of a Novel Synthetic Polymer Nerve Conduit 'Polynerve' in Participants With Sensory Digital Nerve Injury


Condition:   Injury of Nerves at Wrist and Hand Level
Intervention:   Device: Polynerve
Sponsors:   University of Manchester;   National Institute for Health Research, United Kingdom
Not yet recruiting - verified May 2017


MRI Diffusion Tensor Tractography to Track and Monitor Peripheral Nerve Recovery After Severe Crush or Cut/Repair Nerve Injury


Condition:   Nerve Injury
Intervention:   Device: MRI of 3.0T
Sponsors:   Vanderbilt University;   United States Department of Defense
Recruiting - verified May 2017


Prospective Comparison of Adductor Canal Block Performed With a Multiport Versus Single Bevel Needle


Condition:   Peripheral Nerve Injuries
Intervention:  
Sponsor:   University of Utah
Recruiting - verified May 2016


Study of Nerve Repair and Reconstruction Associated With Major Extremity Trauma


Condition:   Peripheral Nerve Injury(Ies)
Intervention:  
Sponsor:   Major Extremity Trauma Research Consortium
Recruiting - verified April 2017


Cortical Effects of Peripheral Nerve Injury At Birth


Condition:   Peripheral Nerve Injury
Intervention:  
Sponsors:   Gazi University;   Ataturk Training and Research Hospital
Not yet recruiting - verified August 2016


Therapeutic Resistance Group Exercise Training for Head & Neck Cancer Survivors


Conditions:   Head and Neck Neoplasms;   Accessory Nerve Injury;   Fatigue
Interventions:   Behavioral: Therapeutic Exercise;   Behavioral: Therapeutic + Lower Body Exercise
Sponsors:   University of Alberta;   Cross Cancer Institute
Recruiting - verified October 2016


Vagus Nerve Injury Post Radiofrequency Catheter Ablation for Atrial Fibrillation


Conditions:   Atrial Fibrillation;   Gastrointestinal Tract;   Radiofrequency Catheter Ablation
Intervention:  
Sponsor:   Intermountain Health Care, Inc.
Completed - verified June 2016


Axial Length and Central Corneal Thickness in Benign Intracranial Hypertension


Condition:   Benign Intracranial Hypertension
Interventions:   Device: Pachette3;   Device: Lenstar-Think
Sponsor:   Ochsner Health System
Suspended - verified April 2017


Emergent Expanded Access for ahSC Augmentation of Nerve Autografts After Severe Peripheral Nerve Injury.


Condition:   Sciatic Nerve Injury
Intervention:   Biological: Autologous human Schwann cells
Sponsors:   W. Dalton Dietrich;   The Miami Project to Cure Paralysis
Temporarily not available - verified January 2017


Expanded Access for Single Patient Treatment of Autologous Human Schwann Cells (ahSC) for Peripheral Nerve Repair


Condition:   Sciatic Nerve Injury
Intervention:   Biological: Autologous Human Schwann cells
Sponsors:   W. Dalton Dietrich;   The Miami Project to Cure Paralysis
No longer available - verified March 2017


Performance Study of an Artificial Nerve Guide (Reaxon® Nerve Guide) to Treat Digital Nerve Lesions


Condition:   Peripheral Nerve Injuries
Intervention:   Device: Implantation
Sponsor:   Medovent GmbH
Recruiting - verified July 2016


Nerve Repair Using Hydrophilic Polymers to Promote Immediate Fusion of Severed Axons and Swift Return of Function


Condition:   Peripheral Nerve Injury
Intervention:   Drug: Polyethylene glycol (PEG)
Sponsor:   Vanderbilt University
Recruiting - verified May 2017


Study of Capsaicin Patch for the Management of Peripheral Neuropathic Pain


Conditions:   Peripheral Nerve Injury;   Postherpetic Neuralgia
Interventions:   Drug: CAPNP, 50 ug/cm2 capsaicin patch;   Drug: CAPNP, 100 ug/cm2 capsaicin patch;   Drug: 0.075% capsaicin cream;   Other: Placebo patch
Sponsor:   Samyang Biopharmaceuticals Corporation
Completed - verified September 2014


Somatosensory Assessment and Rehabilitation of Allodynia (SARA)


Conditions:   Complex Regional Pain Syndrome;   Peripheral Nerve Injuries;   Hand Fractures
Interventions:   Other: Somatosensory rehabilitation;   Other: Usual treatment: physiotherapy
Sponsors:   Hamilton Health Sciences Corporation;   Canadian Institutes of Health Research (CIHR)
Active, not recruiting - verified January 2017


Safety and Efficacy Study of RPh201 Treatment of Ischemic Optic Neuropathy (ION).


Conditions:   Non-arteritic Ischemic Optic Neuropathy;   Optic Nerve Injuries
Interventions:   Drug: RPh201;   Drug: Placebo
Sponsor:   Regenera Pharma Ltd
Completed - verified December 2016


Micro-Electrodes Implanted in a Human Nerve


Conditions:   Amputations;   Peripheral Nerve Injury;   Spinal Cord Injury
Intervention:   Device: Utah Slanted Electrode Array
Sponsor:   University of Utah
Enrolling by invitation - verified February 2017


Optimization of Peripheral Nerve Reconstruction: A Non-inferiority Trial


Condition:   Peripheral Nerve Injury Digital Nerve Hand Left
Intervention:  
Sponsor:   University Hospital, Basel, Switzerland
Recruiting - verified October 2016


Molecular-Genetic Mechanisms Associated With Chemotherapy-Induced Nerve Damage


Conditions:   Peripheral Neuropathic Pain;   Neurotoxicity;   Cancer
Intervention:  
Sponsor:   National Institute of Nursing Research (NINR)
Terminated - verified November 13, 2012


Paraorbital-Occipital Alternating Current Stimulation Therapy for Optic Neuropathy (MCT_optnerve)


Conditions:   Optic Nerve Diseases;   Optic Nerve Injuries;   Optic Neuropathies
Interventions:   Device: tACS;   Device: Sham stimulation
Sponsors:   University of Magdeburg;   EBS Technologies GmbH
Completed - verified January 2017


Study in Neuropathic Pain Patients With Peripheral Nerve Injury


Condition:   Pain, Neuropathic
Interventions:   Drug: GW856553;   Drug: PLACEBO
Sponsor:   GlaxoSmithKline
Completed - verified February 2017

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