Migraines



Intracranial Pressure During Migraine


Condition:   Menstrual Migraine
Intervention:   Other: Intracranial pressure variations
Sponsor:   University Hospital, Clermont-Ferrand
Recruiting - verified May 2017


Melatonin for Adolescent Migraine Prevention Study


Condition:   Migraine
Interventions:   Drug: Melatonin;   Drug: Placebo oral capsule
Sponsors:   Amy Gelfand;   University of California, Los Angeles
Not yet recruiting - verified May 2017


MigraineManager: An Individualized Self-Management Tool for Adolescents With Migraine


Condition:   Migraine Disorders
Intervention:   Behavioral: MigraineManager: Individualized Self-Management Tool
Sponsor:   Children's Hospital Medical Center, Cincinnati
Not yet recruiting - verified May 2017


Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine


Condition:   Chronic Migraine
Interventions:   Drug: IONIS-PKKRx (ISIS 546254);   Other: Placebo
Sponsors:   Smith, Timothy R., M.D.;   Clinvest Research, LLC;   Ionis Pharmaceuticals, Inc.
Not yet recruiting - verified April 2017


Improving Health Outcomes of Migraine Patients Who Present to the Emergency Department


Condition:   Migraine
Interventions:   Drug: Preventative Medication (PM) Topiramate, Naproxen or Triptan;   Behavioral: Enhanced Usual Care;   Behavioral: PMR (progressive muscle relaxation therapy)
Sponsor:   New York University School of Medicine
Not yet recruiting - verified October 2016


Investigation and Modulation of the Mu-Opioid Mechanisms in Migraine (in Vivo)


Condition:   Migraine
Interventions:   Device: Active Comparator;   Device: Sham Comparator
Sponsors:   University of Michigan;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified November 2016


Pain Processing in Adults With Migraines


Condition:   Migraines
Interventions:   Other: Questionnaires;   Other: Quantitative Sensory Testing (QST) Pain Measurements
Sponsor:   Wake Forest University Health Sciences
Recruiting - verified September 2016


Mindfulness and Mechanisms of Pain Processing in Adults With Migraines


Condition:   Migraine
Interventions:   Other: Mindfulness Based Stress Reduction;   Other: Migraine/stress Education
Sponsor:   Wake Forest University Health Sciences
Recruiting - verified April 2017


A Safety and Efficacy Study to Evaluate AMG 334 in Migraine Prevention


Condition:   Migraine
Interventions:   Drug: AMG 334 Dose Level 1;   Drug: Placebo;   Drug: AMG 334 Dose Level 2;   Drug: AMG 334 Dose Level 3
Sponsor:   Amgen
Active, not recruiting - verified April 2017


Study of Key Electro-acupuncture Technique on Migraine


Condition:   Migraine
Interventions:   Device: electro-acupuncture;   Drug: flunarizine hydrochloride
Sponsor:   Shanghai University of Traditional Chinese Medicine
Recruiting - verified November 2016


Study to Evaluate the Efficacy and Safety of AMG 334 in Migraine Prevention


Condition:   Migraine
Interventions:   Drug: AMG 334;   Drug: AMG 334;   Drug: Placebo
Sponsor:   Amgen
Active, not recruiting - verified January 2017


Cefalium® Compared to Tylenol® in the Treatment of Migraine Attacks


Condition:   Migraine
Interventions:   Drug: Acetaminophen+Caffeine+Dihydroergotamine+Metoclopramide.;   Drug: Acetaminophen
Sponsor:   Ache Laboratorios Farmaceuticos S.A.
Not yet recruiting - verified February 2017


A Study to Evaluate Botulinum Toxin Type A for Injection(HengLi®)for Prophylactic Treatment of Chronic Migraine


Condition:   Chronic Migraine
Interventions:   Drug: Botulinum Toxin Type A for Injection;   Drug: Placebo
Sponsor:   Lanzhou Institute of Biological Products Co., Ltd
Enrolling by invitation - verified September 2016


A Multicenter Assessment of ALD403 in Chronic Migraine


Condition:   Migraine Disorders
Interventions:   Biological: ALD403;   Biological: Placebo
Sponsor:   Alder Biopharmaceuticals, Inc.
Completed - verified May 2016


Trial of Nortriptyline and Topiramate in the Initial Treatment of Vestibular Migraine


Condition:   Migraine Disorders
Interventions:   Drug: nortriptyline;   Drug: Topiramate
Sponsor:   St. Louis University
Recruiting - verified November 2016


A Phase 2 Study to Evaluate the Efficacy and Safety of AMG 334 in Migraine Prevention


Condition:   Migraine
Interventions:   Drug: AMG 334;   Drug: Placebo
Sponsor:   Amgen
Active, not recruiting - verified January 2017


Normobaric Oxygen (NBO) Therapy in Acute Migraine


Condition:   Migraine
Interventions:   Biological: Oxygen;   Biological: Room air
Sponsor:   Massachusetts General Hospital
Completed - verified February 2017


Structural and Molecular Neuroplasticity in Migraine


Condition:   Migraine
Interventions:   Procedure: Pet Scan;   Procedure: MRI scan;   Procedure: Quantitative Sensory Testing (QST)
Sponsor:   University of Michigan
Completed - verified December 2016


A Double-blind, Placebo-controlled Pilot Study to Collect and Evaluate Data on the Use of Intravenous Ibuprofen in the Treatment of an Acute Migraine Attack


Condition:   Episodic Migraine
Interventions:   Other: saline placebo;   Drug: Ibuprofen
Sponsor:   Thomas Jefferson University
Recruiting - verified June 2016


Ictal and Interictal Inflammatory Markers in Migraine


Condition:   Migraine
Interventions:   Drug: Treximet;   Drug: Placebo
Sponsors:   Johns Hopkins University;   University of Toledo Health Science Campus;   The Cleveland Clinic
Completed - verified August 2016


Migraine--Investigational Treatment of Migraine With Noninvasive Brain Stimulation. (tDCS- Migraine)


Condition:   Migraine
Intervention:   Device: DC Stimulator (Transcranial Direct Current Stimulator)
Sponsor:   Beth Israel Deaconess Medical Center
Completed - verified March 2017


Staccato Loxapine in Migraine (in Clinic)


Condition:   Migraine
Interventions:   Drug: Staccato Loxapine;   Drug: Staccato Placebo
Sponsor:   Alexza Pharmaceuticals, Inc.
Completed - verified April 2008


Efficacy and Safety of Intranasal Ketorolac for the Acute Treatment of Migraine


Condition:   Migraine
Interventions:   Drug: Ketorolac tromethamine;   Drug: Placebo
Sponsor:   Egalet Ltd
Completed - verified September 2016


Multiple Attacks Study to Compare the Efficacy and Safety of MK-0974 With Placebo for Acute Migraine (MK-0974-031)


Condition:   Migraines
Interventions:   Drug: Telcagepant 140 mg;   Drug: Talcagepant 280 mg;   Drug: Placebo
Sponsor:   Merck Sharp & Dohme Corp.
Completed - verified April 2017


Treatment for Migraines With an Implantable Device


Condition:   Migraine
Intervention:   Device: Precision
Sponsor:   Boston Scientific Corporation
Active, not recruiting - verified January 2017

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