Migraines



A Study to Evaluate the Long-Term Safety of M207 in the Acute Treatment of Migraine


Condition:   Migraine
Intervention:   Drug: M207 Microneedle System
Sponsor:   Zosano Pharma Corporation
Not yet recruiting


Open Label Safety Study in Acute Treatment of Migraine


Condition:   Migraine
Intervention:   Drug: Rimegepant
Sponsor:   Biohaven Pharmaceutical Holding Company Ltd.
Recruiting


OnabotulinumtoxinA Injections in Chronic Migraine, Targeted to Sites of Pericranial Myofascial Pain


Condition:   Chronic Migraine
Intervention:  
Sponsor:   University Hospital, Limoges
Completed


MigraineManager: An Individualized Self-Management Tool for Adolescents With Migraine


Condition:   Migraine Disorders
Intervention:   Behavioral: MigraineManager: Individualized Self-Management Tool
Sponsor:   Children's Hospital Medical Center, Cincinnati
Not yet recruiting


Intracranial Pressure During Migraine


Condition:   Menstrual Migraine
Intervention:   Other: Intracranial pressure variations
Sponsor:   University Hospital, Clermont-Ferrand
Recruiting


Efficacy and Safety of IONIS-PKKRx for Preventive Treatment of Chronic Migraine


Condition:   Chronic Migraine
Interventions:   Drug: IONIS-PKKRx (ISIS 546254);   Other: Placebo
Sponsors:   Smith, Timothy R., M.D.;   Clinvest Research, LLC;   Ionis Pharmaceuticals, Inc.
Recruiting


Structural and Molecular Neuroplasticity in Migraine


Condition:   Migraine
Interventions:   Procedure: Pet Scan;   Procedure: MRI scan;   Procedure: Quantitative Sensory Testing (QST)
Sponsor:   University of Michigan
Completed


Investigation and Modulation of the Mu-Opioid Mechanisms in Migraine (in Vivo)


Condition:   Migraine
Interventions:   Device: Active Comparator;   Device: Sham Comparator
Sponsors:   University of Michigan;   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting


A Safety and Efficacy Study to Evaluate AMG 334 in Migraine Prevention


Condition:   Migraine
Interventions:   Drug: AMG 334 Dose Level 1;   Drug: Placebo;   Drug: AMG 334 Dose Level 2;   Drug: AMG 334 Dose Level 3
Sponsor:   Amgen
Active, not recruiting


Study of Key Electro-acupuncture Technique on Migraine


Condition:   Migraine
Interventions:   Device: electro-acupuncture;   Drug: flunarizine hydrochloride
Sponsor:   Shanghai University of Traditional Chinese Medicine
Recruiting


Pharmacokinetics & Safety of Cambia® in Migraine With or Without Aura in 12-17 Year Olds


Condition:   Migraine
Intervention:   Drug: Diclofenac Potassium for Oral Solution
Sponsor:   Depomed
Completed


A Multicenter Assessment of ALD403 in Chronic Migraine


Condition:   Migraine Disorders
Interventions:   Biological: ALD403;   Biological: Placebo
Sponsor:   Alder Biopharmaceuticals, Inc.
Completed


Trial of Nortriptyline and Topiramate in the Initial Treatment of Vestibular Migraine


Condition:   Migraine Disorders
Interventions:   Drug: nortriptyline;   Drug: Topiramate
Sponsor:   St. Louis University
Recruiting


Nutrition for Migraine Prevention


Condition:   Migraine Disorders
Intervention:   Other: Diet
Sponsors:   University of North Carolina, Chapel Hill;   National Center for Complementary and Integrative Health (NCCIH)
Recruiting


A Phase 2 Study to Evaluate the Efficacy and Safety of AMG 334 in Migraine Prevention


Condition:   Migraine
Interventions:   Drug: AMG 334;   Drug: Placebo
Sponsor:   Amgen
Active, not recruiting


Normobaric Oxygen (NBO) Therapy in Acute Migraine


Condition:   Migraine
Interventions:   Biological: Oxygen;   Biological: Room air
Sponsor:   Massachusetts General Hospital
Completed


Milnacipran for Migraine Pain


Condition:   Chronic Migraine
Interventions:   Drug: Milnacipran;   Drug: Placebo
Sponsor:   Timothy Smith
Completed


The Coherex FlatStent™ EF PFO Migraine Registry


Condition:   Patients With Migraine and PFO
Intervention:   Device: Transcatheter PFO Closure
Sponsor:   Coherex Medical
Terminated


Mechanism-based Choice of Therapy for Pain: Can Successful Prevention of Migraine be Coupled to a Psychophysical Pain Modulation Profile?


Condition:   Migraine
Interventions:   Drug: Amitriptyline;   Drug: Topiramate
Sponsor:   Rambam Health Care Campus
Completed


Telcagepant for Prevention of Menstrually Related Migraine in Female Participants With Episodic Migraine (MK-0974-065)


Condition:   Migraine
Interventions:   Drug: Telcagepant;   Drug: Placebo
Sponsor:   Merck Sharp & Dohme Corp.
Completed


A Study to Evaluate the Efficacy and Tolerability of Rizatriptan for Treatment of Acute Migraine (0462-087)


Condition:   Acute Migraine
Interventions:   Drug: rizatriptan;   Drug: Comparator: Placebo;   Drug: Comparator: Sumatriptan
Sponsor:   Merck Sharp & Dohme Corp.
Completed


Migraine--Investigational Treatment of Migraine With Noninvasive Brain Stimulation. (tDCS- Migraine)


Condition:   Migraine
Intervention:   Device: DC Stimulator (Transcranial Direct Current Stimulator)
Sponsor:   Beth Israel Deaconess Medical Center
Completed


Staccato Loxapine in Migraine (in Clinic)


Condition:   Migraine
Interventions:   Drug: Staccato Loxapine;   Drug: Staccato Placebo
Sponsor:   Alexza Pharmaceuticals, Inc.
Completed


Multiple Attacks Study to Compare the Efficacy and Safety of MK-0974 With Placebo for Acute Migraine (MK-0974-031)


Condition:   Migraines
Interventions:   Drug: Telcagepant 140 mg;   Drug: Talcagepant 280 mg;   Drug: Placebo
Sponsor:   Merck Sharp & Dohme Corp.
Completed


A Study Designed to Test the Effectiveness and Safety of Treating Patients With Lacosamide for Migraine Prophylaxis


Condition:   Migraine
Interventions:   Drug: Lacosamide;   Other: Placebo
Sponsor:   UCB Pharma
Completed

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