Brain Tumors



Local Control, Quality of Life and Toxicities in Adults With Benign or Indolent Brain Tumors Undergoing Proton Radiation Therapy


Condition:   Brain Tumor
Intervention:   Radiation: Proton Radiation
Sponsor:   Massachusetts General Hospital
Not yet recruiting


[18F]Fluciclovine and [18F]FLT PET/CT Assessment of Primary High-Grade Brain Tumors


Condition:   Brain Tumor
Intervention:   Drug: Multi-tracer PET exams of [18F]FLT and [18F]Fluciclovine
Sponsors:   University of Utah;   Blue Earth Diagnostics
Not yet recruiting


The Purpose of This Study is to Test Any Good and Bad Effects of a Study Drug Called Abemaciclib (LY2835219) in Patients With Recurrent Brain Tumors.


Condition:   Brain Tumor
Intervention:   Drug: abemaciclib
Sponsors:   Memorial Sloan Kettering Cancer Center;   Eli Lilly and Company
Recruiting


Evaluation of Cognitive-Communication Deficits Following Treatment of Primary Brain Tumor Patients


Condition:   Brain Tumor
Intervention:   Other: Cognitive Surveys
Sponsor:   Mayo Clinic
Recruiting


Multi-Parametric Quantitative MR Imaging in Evaluation of Brain Tumors


Condition:   Brain Tumor
Intervention:   Device: Magnetic Resonance Fingerprinting
Sponsor:   Case Comprehensive Cancer Center
Not yet recruiting


Pilot Study of Safety and Toxicity of Acquiring Hyperpolarized Carbon-13 Imaging in Children With Brain Tumors


Condition:   Pediatric Brain Tumors
Intervention:   Drug: Hyperpolarized Pyruvate
Sponsor:   University of California, San Francisco
Recruiting


Cognitive Biomarkers in Pediatric Brain Tumor Patients


Condition:   Childhood Brain Tumor
Interventions:   Other: Neurocognitive testing;   Device: rsfcMRI
Sponsor:   Washington University School of Medicine
Recruiting


Comparison of Proton and Photon Radiotherapy of Brain Tumors (ProtoChoice-Hirn)


Condition:   Brain Tumors
Interventions:   Radiation: Radiation with protons;   Radiation: Radiation with photons
Sponsors:   Technische Universität Dresden;   German Cancer Consortium (DKTK);   National Center for Radiation Research in Oncology Dresden/Heidelberg
Recruiting


Using Electrocorticogram (ECoG) in Predicting Eloquent Cortex and Post-Op Functional Outcomes in Patients With Brain Tumors


Condition:   Brain Tumor
Interventions:   Procedure: Electrocorticography (ECoG) with PMT Grids;   Procedure: Electrocorticography (ECoG) with CorTec Grids;   Procedure: Digital Glove Procedure;   Procedure: Neurological Exam;   Procedure: Electrocorticography (ECoG) with Ad-Tech Grids;   Procedure: Direct Electrical Stimulation Mapping;   Procedure: Grip Sensor Procedure
Sponsor:   M.D. Anderson Cancer Center
Recruiting


Multi-Parametric Brain Cancer MRI


Condition:   Brain Tumors
Intervention:   Other: 3D MRI Scans
Sponsor:   AHS Cancer Control Alberta
Active, not recruiting


Frailty as a Predictor of Neurosurgical Outcomes in Brain Tumor Patients


Condition:   Brain Tumors
Intervention:  
Sponsor:   University of Colorado, Denver
Recruiting


Cognitive Intervention After a Brain Tumor


Condition:   Brain Tumors
Interventions:   Behavioral: Brain Training Program;   Behavioral: Brain Health Program
Sponsor:   University Health Network, Toronto
Active, not recruiting


Assessment of Cognitive Functions and Quality of Life in Patients Undergoing Surgery for Supratentorial Brain Tumor


Condition:   Brain Tumor
Interventions:   Drug: Propofol;   Drug: Sevoflurane
Sponsor:   All India Institute of Medical Sciences, New Delhi
Not yet recruiting


Tryptophan Metabolism in Human Brain Tumors


Condition:   Brain Tumors
Intervention:  
Sponsors:   Wayne State University;   National Cancer Institute (NCI)
Recruiting


Electronic Medical Record Review in Monitoring the Effects of Adherence on Myelosuppression and Morbidity in Patients With Newly Diagnosed Brain Tumors Receiving Temozolomide and Radiation Therapy


Condition:   Brain Tumor
Intervention:   Other: medical chart review
Sponsors:   Wake Forest University Health Sciences;   National Cancer Institute (NCI)
Completed


Neuroplasticity-Based Cognitive Remediation for Pediatric Brain Tumor Survivors


Condition:   Brain Tumor
Intervention:   Behavioral: Cognitive training
Sponsors:   Vanderbilt University;   National Cancer Institute (NCI)
Recruiting


Efficacy Evaluation of Dotarem®-Enhanced MRI Compared to Gadovist®/Gadavist®-Enhanced MRI in the Diagnosis of Brain Tumors


Condition:   Primary Brain Tumor
Interventions:   Drug: Dotarem®;   Drug: Gadovist®/Gadavist®
Sponsor:   Guerbet
Completed


MRI-Guided LITT for Treatment Metastatic Brain Tumors


Condition:   Brain Tumor
Intervention:   Device: Visualase®
Sponsor:   The Methodist Hospital System
Completed


Assessment of Eloquent Function in Brain Tumor Patients


Conditions:   Primary Brain Tumor;   Metastatic Brain Tumor
Intervention:  
Sponsor:   University of Nebraska
Recruiting


Florida Center for Brain Tumor Research


Condition:   Brain Tumors
Intervention:   Procedure: Tissue Bank
Sponsor:   University of Florida
Recruiting


Evaluation of Human Brain Tumor Therapy Response by Magnetic Resonance (MR)


Condition:   Brain Tumors
Intervention:   Procedure: MRI
Sponsors:   University of Michigan;   National Institutes of Health (NIH);   National Cancer Institute (NCI)
Recruiting


Working Memory Performance Among Childhood Brain Tumor Survivors


Condition:   Brain Tumors
Intervention:   Behavioral: Series of tests/questionnaires
Sponsors:   St. Jude Children's Research Hospital;   National Cancer Institute (NCI)
Completed


Temozolomide,Thiotepa and Carboplatin With Autologous Stem Cell Rescue Followed by 13-cis-retinoic Acid in Patients With Recurrent/Refractory Malignant Brain Tumors


Condition:   Brain Tumors
Intervention:   Drug: temozolomide, thiotepa, carboplatin, 13-cis-retinoic acid
Sponsors:   New York University School of Medicine;   Children's Hospitals and Clinics of Minnesota;   Schneider Children's Hospital
Active, not recruiting


A Case-Referent Study of Brain Tumors in Adults


Condition:   Brain Tumors
Intervention:  
Sponsors:   National Cancer Institute (NCI);   Centers for Disease Control and Prevention;   National Institute for Occupational Safety and Health (NIOSH/CDC)
Completed


MRI-Guided Focused Ultrasound Feasibility Study for Brain Tumors


Condition:   Brain Tumor
Intervention:   Device: ExAblate transcranial system
Sponsor:   InSightec
Recruiting

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