A Comparative Effectiveness Randomised Placebo Controlled Pilot Trial of the Management of Acute Lumbar Radicular Pain

Condition:   Acute Sciatica
Interventions:   Drug: Betamethasone OR Dexamethasone Injectable;   Drug: Normal Saline Flush, 0.9% Injectable Solution;   Drug: Dexamethasone Oral Tablet;   Other: Sham Injection and/or oral placebo
Sponsors:   St George Hospital, Australia;   St George & Sutherland Medical Research Foundation

Pentoxifylline and Lumbar Radiculopathy

Conditions:   Lumbar Radiculopathy;   Lumbar Disc Herniation;   Lumbar Disc Disease
Interventions:   Drug: Pentoxifylline Oral Tablet;   Drug: Ibuprofen
Sponsor:   St Joseph University, Beirut, Lebanon

Effectiveness and Safety of Korean Medicine for Lumbar Stenosis Patients With Sciatica

Condition:   Lumbar Spinal Stenosis
Interventions:   Drug: Herbal medicine;   Procedure: Chuna manipulation;   Procedure: Bee venom pharmacopuncture;   Procedure: Pharmacopuncture;   Procedure: Acupuncture;   Procedure: Electroacupuncture;   Procedure: Cupping;   Other: Other intervention(s)
Sponsor:   Jaseng Medical Foundation

Mechanical Diagnosis and Treatment and/or Steroid Injections for Lumbar Radiculopathy

Conditions:   Sciatica;   Lumbosacral Radiculopathy;   Lumbar Disc Rupture
Interventions:   Other: Exercise (MDT approach);   Drug: Transforaminal epidural steroid injection (20mg dexamethasone 0.5cc lidocaine 2%)
Sponsors:   University of Alberta;   University of Calgary;   Alberta College and Association of Phyiotherapists
Not yet recruiting

Clinical Trial to Evaluate the Safety and Analgesic Efficacy of VVZ-149 in Lumbar Radiculopathy (Sciatica)

Conditions:   Radiculopathy;   Sciatica
Interventions:   Drug: VVZ-149;   Drug: Lidocaine;   Drug: Placebo
Sponsor:   Brigham and Women's Hospital

Physiotherapy for Sciatica; Is Earlier Better?

Conditions:   Sciatica;   Low Back Pain;   Radiculopathy
Intervention:   Other: Physiotherapy
Sponsors:   Michael Reddington;   National Institute for Health Research, United Kingdom

"The Lived Experience of Investigations for Sciatica"

Condition:   Sciatica
Intervention:   Other: No intervention applied
Sponsors:   University of Southampton;   Solent NHS Trust
Unknown status

Effects of Shinbaro Pharmacopuncture in Sciatic Pain Patients With Lumbar Disc Herniation

Conditions:   Sciatica;   Intervertebral Disc Displacement
Interventions:   Procedure: Shinbaro pharmacopuncture;   Device: Acupuncture;   Drug: Conventional medicine;   Procedure: Physical therapy;   Behavioral: Educational program
Sponsor:   Jaseng Medical Foundation

Intradiscal Discogel® in Resistant Sciatica

Conditions:   Herniated Disc;   Sciatica;   Persistent Pain, Leg
Interventions:   Device: Chemonucleolysis with Discogel;   Procedure: open discectomy
Sponsors:   Assistance Publique - Hôpitaux de Paris;   Gelscom SAS
Not yet recruiting

NAPS: Non-awake Versus Awake Placement of Spinal Cord Stimulators

Conditions:   Chronic Pain;   Sciatica;   Failed Back Surgery Syndrome
Interventions:   Procedure: Awake;   Procedure: Non-Awake
Sponsors:   St. Luke's Hospital, Pennsylvania;   St. Jude Medical

PET/MRI Imaging of Neuraxial Inflammation in Sciatica Patients

Condition:   Sciatica
Interventions:   Drug: Radioactive dye;   Radiation: PET/MRI;   Other: Blood draw
Sponsor:   Massachusetts General Hospital
Active, not recruiting

Navigator vs Standard Needle Injection for Hip

Condition:   Hip Pain Etiology Unknown
Interventions:   Drug: Celestone;   Drug: Lidocaine
Sponsor:   Cartiva, Inc.

Ultrasound Guided Posterior Sacroiliac Ligament Corticosteroid Injection in Pregnancy-Related Pelvic Girdle Pain

Condition:   Pelvic Girdle Pain
Interventions:   Drug: Corticosteroid;   Drug: Placebo Injection
Sponsors:   Loyola University;   American Academy of Physical Medicine and Rehabilitation

A Study of the Pharmacokinetics, Safety, and Preliminary Efficacy of MDT-15 in Subjects With Lumbosacral Radiculopathy

Conditions:   Sciatica;   Lumbosacral Radiculopathy
Intervention:   Drug: MDT-15
Sponsor:   Medtronic Spinal and Biologics

Prediction of Inter-individual Differences in the Response to Morphine Versus Milnacipran in Patients With Sciatica

Condition:   Neuropathic Pain
Interventions:   Drug: Morphine;   Drug: Milnacipran
Sponsor:   Rambam Health Care Campus

Chiropractic Spinal Manipulative Therapy for Acute Sciatica Secondary to Lumbar Disc Herniation

Conditions:   Acute Sciatica;   Lumbar Disc Herniation
Interventions:   Other: Chiropractic Spinal Manipulative Therapy;   Other: Usual Care
Sponsor:   Vancouver General Hospital
Active, not recruiting

Steroids Versus Gabapentin

Conditions:   Sciatica;   Radiculopathy
Interventions:   Procedure: epidural steroid injection;   Procedure: Sham epidural steroid injection;   Drug: Gabapentin;   Drug: Placebo gabapentin
Sponsors:   Johns Hopkins University;   Walter Reed National Military Medical Center;   Brooke Army Medical Center;   Landstuhl Regional Medical Center;   Washington D.C. Veterans Affairs Medical Center;   United States Naval Medical Center, San Diego;   Case Western Reserve University;   Milton S. Hershey Medical Center

Study to Evaluate the Effectiveness of Orthopedic Spinal Supports in the Treatment of Low Back Pain

Condition:   Low Back Pain
Intervention:   Device: Back supports
Sponsors:   Cleveland Clinic Florida;   Integral Orthopedics Inc.

Blood Sample Donations to Study the Role of Genes in Pain

Condition:   Pain
Sponsor:   National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Pain Treatment for Sciatica

Conditions:   Radiculopathy;   Sciatica
Interventions:   Drug: Nortriptyline;   Drug: Morphine
Sponsor:   National Institute of Dental and Craniofacial Research (NIDCR)

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