Knee Pain



Randomized, Multi-Dose, Placebo-Controlled OA Knee Pain Relief Study of 0.25% 920-CGS-200


Condition:   Osteoarthritis, Knee
Interventions:   Drug: Capsaicin Topical Solution;   Other: Drug product vehicle
Sponsors:   Vizuri Health Sciences LLC;   Palm Beach CRO
Completed - verified April 2017


A Trial to Assess the Pain-control Efficacy of Intra-articular Toradol Compared to Oral NSAIDs


Condition:   Arthritic Knee Pain
Interventions:   Drug: Toradol;   Drug: Oral NSAID
Sponsor:   The University of Texas Health Science Center, Houston
Not yet recruiting - verified November 2016


Genicular Radiofrequency Ablation Efficacy in Achieving Total Knee Pain Reduction Trial


Conditions:   Knee Arthroplasty, Total;   Osteoarthritis;   Radiologic Tibiofemoral Osteoarthritis
Interventions:   Procedure: Genicular Nerve RFA;   Procedure: Sham Genicular Nerve RFA;   Drug: Lidocaine
Sponsor:   Vanderbilt University
Not yet recruiting - verified October 2016


Radiofrequency For Chronic Knee Pain Post-Arthroplasty


Conditions:   Chronic Knee Pain;   Osteoarthritis, Knee
Interventions:   Procedure: Nerve Block with Radiofrequency Ablation;   Procedure: Nerve Block with Sham Radiofrequency Ablation
Sponsors:   Randall Brewer, MD, CPI;   St. Jude Medical
Recruiting - verified March 2017


Changes of Plantar Pressure After Knee Reconstructive Surgery


Condition:   Knee Pain Treated With Knee Arthroplasty
Intervention:   Procedure: Surgery
Sponsor:   Technische Universität München
Recruiting - verified September 2016


Dry Needling and Knee Pain


Conditions:   Patellofemoral Pain Syndrome;   Anterior Knee Pain Syndrome
Interventions:   Procedure: Dry Needling;   Procedure: Sham Dry Needling;   Other: Physical Therapy
Sponsor:   Ohio State University
Recruiting - verified August 2016


5 Year Follow-up of Adolescents With Knee Pain


Conditions:   Patellofemoral Pain Syndrome;   Knee Pain
Intervention:   Other: No intervention
Sponsors:   Aalborg University;   Research Unit for General Practice in Aalborg;   University of Southern Denmark;   Copenhagen University Hospital, Denmark
Completed - verified January 2017


Evaluating Light Therapy for Treatment of Overuse Anterior Knee Pain


Condition:   Anterior Knee Pain Syndrome
Interventions:   Device: THOR laser LX2 system;   Device: Sham
Sponsors:   Hebrew University of Jerusalem;   Shaare Zedek Medical Center;   International Diabetes Federation
Enrolling by invitation - verified February 2017


Geniculate Artery Embolization for the Treatment of Knee Pain


Condition:   Osteoarthritis Of Knee
Intervention:   Device: Geniculate Artery Embolization
Sponsor:   University of North Carolina, Chapel Hill
Recruiting - verified December 2016


Effect of Cis-9-cetylmyristoleate in Sub-healthy Subjects Presenting With Knee Joint Pain


Condition:   Knee Pain Intermittent
Interventions:   Dietary Supplement: JOINTRUS®;   Dietary Supplement: 80% dose of JOINTRUS®;   Dietary Supplement: 62.4% dose of JOINTRUS®;   Dietary Supplement: Starch 100%
Sponsor:   Seoul National University
Completed - verified June 2016


Combined Application of Electrical Stimulation and Volitional Contractions for Muscle Strengthening and Knee Pain Inhibition (Seated Study)


Condition:   Knee Osteoarthritis
Interventions:   Device: Electrodes (Sekisui Plastics Co.) and Joint Motion Sensors (Mutoh Engineering, Inc.);   Device: Isokinetic Training with Computer Sports Medicine Inc. (CSMi) HUMAC NORM
Sponsors:   University of Kansas Medical Center;   Kurume University
Completed - verified February 2017


Neural Mechanisms of Muscle Control in Individuals With Knee Pain


Condition:   Patellofemoral Pain Syndrome
Intervention:   Behavioral: Muscle activation exercises
Sponsor:   University of Southern California
Not yet recruiting - verified August 2016


Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Chronic, Moderate to Severe Osteoarthritis Knee Pain


Condition:   Osteoarthritis
Interventions:   Drug: CNTX-4975;   Other: Placebo
Sponsor:   Centrexion Therapeutics
Completed - verified March 2017


Transcranial Direct Current Stimulation in Older Persons With Knee Pain (Knee Pain and tDCS): Randomized Pilot Study


Condition:   Knee Osteoarthritis
Interventions:   Device: Active tDCS;   Device: Sham tDCS;   Other: X-Ray;   Other: Walking Test;   Other: Assessment of sensitivity to heat;   Other: Assessment of Sensitivity to Pressure;   Other: Assessment of Sensitivity to Mechanical Stimulation;   Other: Blood Test;   Other: Assessment of balance, chair stand, and gait speed;   Other: Assessment of conditioned pain modulation
Sponsors:   The University of Texas Health Science Center, Houston;   University of Florida
Completed - verified September 2016


Nerve Ablation by Cooled Radiofrequency Compared to Corticosteroid Injection for Management of Knee Pain


Condition:   Osteoarthritis of the Knee
Interventions:   Device: Cooled Radiofrequency;   Drug: Corticosteroid injection
Sponsor:   Halyard Health
Completed - verified February 2017


Manual Therapy to Treat Gluteus Medius Trigger Points


Conditions:   Anterior Knee Pain Syndrome;   Patellofemoral Pain Syndrome
Interventions:   Other: Dry Needling;   Other: Soft Tissue Mobilization;   Other: Placebo Control;   Other: Hip and core strengthening exercises
Sponsor:   Mitchell Selhorst
Recruiting - verified January 2017


Impact of Physical Activity and Vitamin D on Osteoarthritic Knee Pain


Condition:   Knee Osteoarthritis
Interventions:   Dietary Supplement: Vitamin D3 2000IU/daily 3 months;   Behavioral: PA intervention People with Osteoarthritis Walking Programme;   Other: Placebo capsule (Vitamin D): edible oil
Sponsors:   Newcastle University;   Northumbria Healthcare NHS Foundation Trust
Completed - verified August 2016


Serum Levels of Bupivacaine in Autotransfusion Drains Following Total Joint Arthroplasty


Condition:   Knee Pain Arthritis
Intervention:   Drug: periarticular bupivicaine and liposomal bupivicaine
Sponsor:   OrthoCarolina Research Institute, Inc.
Active, not recruiting - verified August 2016


A Study of Duloxetine (LY248686) in Participants With Chronic Osteoarthritis and Knee Pain in Japan


Condition:   Osteoarthritis of the Knee
Interventions:   Drug: Duloxetine;   Drug: Placebo
Sponsors:   Eli Lilly and Company;   Shionogi
Completed - verified November 2016


Pin Size Influence the Incidence of Knee Pain


Condition:   Pain
Intervention:  
Sponsor:   University of Utah
Terminated - verified June 2016


Core Stabilization for the Treatment of Anterior Knee Pain


Condition:   Patellofemoral Pain Syndrome
Interventions:   Other: core stabilization;   Other: lower extremity training only
Sponsor:   Youngstown State University
Recruiting - verified January 2017


Knee Pain Phenotypes in the Community Study


Condition:   Knee Osteoarthritis
Intervention:  
Sponsors:   University of Nottingham;   Arthritis Research UK
Enrolling by invitation - verified February 2017


Virtual Reality for Osteoarthritis Knee Pain Pilot


Condition:   Osteoarthritis of the Knee
Interventions:   Procedure: Virtual Reality Training Session;   Device: 3D viewer with iPod Touch/iPhone (or similar smartphone)
Sponsor:   Duke University
Suspended - verified January 2017


The Parapatellar Approach to Intramedullary Tibial Nailing


Condition:   Knee Pain Intermittent
Intervention:  
Sponsor:   University of Utah
Active, not recruiting - verified February 2017


Safety and Efficacy of Botulinum Toxin A Injection in Patients With Painful Artificial Knee Arthroplasty (TKA)


Condition:   Knee Pain
Interventions:   Drug: Botulinum toxin A;   Drug: Normal Saline
Sponsors:   Minneapolis Veterans Affairs Medical Center;   University of Minnesota - Clinical and Translational Science Institute;   Arthritis Foundation
Completed - verified September 2016

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