Major Depression



Fish Oil as Adjunct Treatment for Major Depressive Disorder


Condition:   Major Depressive Disorder
Interventions:   Dietary Supplement: fish oil capsule;   Dietary Supplement: soybean oil capsule
Sponsors:   Second Xiangya Hospital of Central South University;   Xiangya Hospital of Central South University
Recruiting


Allogeneic HUman Mesenchymal Stem Cell InfusioN Versus Placebo in Subjects With Alcohol Use Disorder and Major DepreSsion.


Conditions:   Major Depression;   Alcohol Use Disorder
Interventions:   Drug: allogeneic human mesenchymal stem cells (allo-hMSCs);   Drug: Placebo
Sponsor:   Joshua M Hare
Not yet recruiting


Remotely Programmed Deep Brain Stimulation of the Bilateral Habeluna for Treatment- Resistant Major Depression: An Open Label Pilot Trial


Condition:   Treatment Resistant Major Depressive Disorder
Interventions:   Procedure: Bilateral surgical implantation of DBS system to Habeluna;   Other: Follow-up Period
Sponsor:   Ruijin Hospital
Recruiting


Eealy Improvement Predicts Antidepressants Response in Adults With Major Depression Disorder


Condition:   Major Depressive Disorder
Intervention:   Drug: antidepressant
Sponsor:   Huashan Hospital
Recruiting


Assessment of Hedonic and Motivational States in Major Depression ( MOODDIS)


Condition:   Major Depression
Intervention:   Behavioral: Computer-based tasks
Sponsor:   Institut National de la Santé Et de la Recherche Médicale, France
Not yet recruiting


Efficacy of H7-Coil DTMS Compared to H1-Coil DTMS in Subjects With Major Depression Disorder (MDD)


Condition:   Major Depressive Disorder (MDD)
Interventions:   Device: H7-Coil;   Device: H1-Coil
Sponsor:   Brainsway
Recruiting


A Study to Evaluate SAGE-217 in Subjects With Moderate to Severe Major Depressive Disorder


Condition:   Major Depression
Interventions:   Drug: SAGE-217;   Drug: Placebo
Sponsor:   Sage Therapeutics
Recruiting


Selenium as Augmentation Treatment for Sertraline Resistant Major Depression


Condition:   Major Depression
Interventions:   Dietary Supplement: selenium supplementation;   Dietary Supplement: placebo
Sponsor:   University of Sao Paulo General Hospital
Recruiting


Impact of tDCS on Emotional Processing in Major Depression


Condition:   Major Depressive Disorder
Intervention:   Device: transcranial direct current stimulation
Sponsor:   Hôpital le Vinatier
Recruiting


Antidepressant Effects of the Glycine Receptor Antagonist AV-101 (4-chlorokynurenine) in Major Depressive Disorder


Condition:   Major Depression
Interventions:   Drug: AV 101 (4-Chlorokynurenine);   Other: Placebo
Sponsor:   National Institute of Mental Health (NIMH)
Recruiting


Evaluation of the Safety of Adjunct Brexpiprazole in Elderly Patients With Major Depressive Disorder and an Inadequate Response to Antidepressant Treatment


Condition:   Major Depression Disorder
Interventions:   Drug: Adjunct brexpiprazole;   Drug: ADT
Sponsor:   H. Lundbeck A/S
Completed


Biomarkers of Fast Acting Therapies in Major Depression


Condition:   Major Depressive Disorder
Intervention:   Drug: Ketamine
Sponsors:   University of California, Los Angeles;   National Institute of Mental Health (NIMH)
Recruiting


Wake and Light Therapy to In-patients With Major Depression: Efficacy, Predictors and Patient Experiences


Condition:   Major Depression
Intervention:   Behavioral: wake therapy
Sponsor:   University of Aarhus
Completed


Mental Health Telemetry for Self-Management in Major Depression


Condition:   Major Depressive Disorder
Intervention:   Device: MHT
Sponsors:   Sunnybrook Health Sciences Centre;   Canadian Institutes of Health Research (CIHR)
Completed


Supplemental Transcranial Magnetic Stimulation (TMS) vs. Standard Medication Monotherapy for Treating Major Depression: An Exploratory Field Study


Condition:   1. Major Depressive Disorder
Interventions:   Device: Supplemental TMS;   Drug: Standard Medication Monotherapy
Sponsors:   Sheppard Pratt Health System;   Central Michigan University
Withdrawn


Brain Inflammation in Major Depressive Disorder Background


Condition:   Major Depression
Intervention:  
Sponsor:   National Institute of Mental Health (NIMH)
Completed


Comparison of Venlafaxine and Fluoxetine in the Treatment of Postmenopausal Women With Major Depression


Condition:   Major Depression
Interventions:   Drug: venlafaxine;   Drug: fluoxetine
Sponsor:   Capital Medical University
Completed


Open Trial of Duloxetine in Outpatients With Irritable Bowel Syndrome Symptoms and Co-Morbid Major Depression


Conditions:   Major Depression;   Irritable Bowel Syndrome
Intervention:   Drug: Duloxetine
Sponsors:   New York State Psychiatric Institute;   Eli Lilly and Company
Completed


Brief Multifamily Psychoeducation for Families of Patients With Chronic Major Depression


Condition:   Major Depressive Disorder
Intervention:   Behavioral: Family psychoeducation
Sponsor:   Nagoya City University
Completed


Feasibility Study to Test Clinical Efficacy of Low Energy AC Magnetic Field to Treat Major Depression


Condition:   Major Depressive Disorder (MDD)
Interventions:   Device: NeoSync EEG Synchronization Therapy;   Device: Sham NeoSync EEG Synchronization Therapy
Sponsor:   NeoSync, Inc.
Completed


Potential Use Of Brain Network Activation Analysis to Diagnose Major Depression


Condition:   Major Depressive Disorder
Intervention:  
Sponsors:   Massachusetts General Hospital;   ElMindA Ltd
Terminated


fMRI Study of Treatment Changes in Major Depression


Conditions:   Major Depression;   Treatment
Interventions:   Drug: Sertraline;   Behavioral: Cognitive Behavioral Therapy
Sponsors:   Washington University School of Medicine;   National Institute of Mental Health (NIMH)
Completed


Compare the Efficacy and Tolerability of the Combination of Aripiprazole and Selective Serotonin Reuptake Inhibitors (SSRIs) Used in Major Depression


Condition:   Major Depressive Disorder
Intervention:   Drug: aripiprazole , sertraline
Sponsor:   Chimei Medical Center
Completed


Cysteamine Therapy for Major Depressive Disorder


Condition:   Major Depressive Disorder
Intervention:   Drug: cysteamine bitartrate
Sponsor:   Icahn School of Medicine at Mount Sinai
Terminated


Major Depressive Disorder Study In Adults


Condition:   Major Depressive Disorder
Intervention:   Drug: paroxetine CR
Sponsor:   GlaxoSmithKline
Completed

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