About Pneumonia Clinical Trials (Click to Open)

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Pneumonia Clinical TrialsGeneral Purpose

The lung inflammation that characterizes pneumonia is typically caused by a bacterial, viral, or fungal infection.

Furthermore, specific groups of individuals are more likely to develop pneumonia than others, including individuals over age 65 and those under the age of 2, as well as those who have pre-existing health problems, including heart failure, diabetes, and COPD.

In light of these known facts about pneumonia, research seeks to improve methods of preventing, diagnosing, and treating pneumonia.

What Will Pneumonia Clinical Trials Be Like?

When participating in a clinical trial for pneumonia, a few common tests and procedures may be involved; however, the ultimate design of the particular study will determine which specific procedures you will undergo.

On a basic level, you may be asked to provide a detailed history describing your symptoms, their duration, severity, and current or recent exposures (i.e., to people, animals, and travel). Your lungs will likely be examined by the study doctor through the use of a stethoscope.

In addition, you may have a chest x-ray to better visualize the infection in your lungs, or to monitor the progress of a specific treatment you are receiving for your pneumonia. Blood tests might also be involved to monitor signs of infection or your response to medications.

You may also be asked to provide a sputum/spit sample, undergo a CT scan (which is an x-ray like procedure that provides detailed images of areas inside your body), or undergo a procedure known as thoracentisis (the removal of fluid from the space between the outside lining of your lungs and the chest wall).

Your pulse and the amount of oxygen in your blood may also be measured, and you may be asked to undergo a bronchoscopy (a procedure in which your doctor inserts a flexible tube with a light on the end through your nose or mouth and into your airways).

Typical Pneumonia Clinical Trial Protocol:

Examples of pneumonia-related clinical trials might include the following:Pneumonia Clinical Trials

  • A study to determine if proactive treatment with antibiotics or antiviral medications in hospitalized patients with heart disease helps to prevent the development of pneumonia.
  • A study to determine the risk of pneumonia among individuals who smoke.
  • A study to determine the effectiveness of a newly-developed antibacterial or antiviral medication in treating pneumonia.
  • A study to determine the accuracy of a newly-developed diagnostic tool or imaging procedure to correctly diagnose the presence of pneumonia.
  • A study designed to determine the risk of developing pneumonia among individuals who received different types of breathing tubes during surgical procedures.

Suggested Search Terms:

“pneumonia children,” “pneumonia treatment,” “pneumonia bacteria,” “pneumonia virus,” “pneumonia COPD,” and “pneumonia surgery.”

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Incidence of pNeumonia and Related ConseqUences in Nursing Home Residents

Condition:   Pneumonia
Intervention:   Other: Data collection on pneumonia events
Sponsor:   University Hospital, Toulouse

Multimometer - Vital Signs Device for Diagnosis of Pneumonia

Condition:   Pneumonia
Intervention:   Device: Multimometer
Sponsors:   University of Alberta;   Grand Challenges Canada

Validation of Thermal Imaging to Detect Pneumonia

Condition:   Pneumonia
Intervention:   Diagnostic Test: Thermal image
Sponsor:   Massachusetts General Hospital

Pneumonia Chart Review Cambodia

Condition:   Pneumonia
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Not yet recruiting

Screening for Pneumonia: A Comparison of Ultra Low Dose Chest CT [ULD-CT] and Conventional Chest Radiography [CXR]

Condition:   Pneumonia
Interventions:   Radiation: ULD-CT;   Radiation: CXR
Sponsor:   Maastricht University Medical Center

Anaerobic Antibiotic Usage for Pneumonia in the Medical Intensive Care Unit

Condition:   Pneumonia
Intervention:   Drug: Antibiotics
Sponsor:   Henry Ford Health System

Diagnostic Use of Lung Ultrasound for Suspected Pneumonia in Nepal

Condition:   Pneumonia
Interventions:   Device: Lung Ultrasound;   Device: Chest X-ray;   Device: Chest Computed Tomography (CT)
Sponsors:   Patan Academy of Health Sciences;   Vanderbilt University;   Indiana University School of Medicine

Trial to Evaluate Beta-Lactam Antimicrobial Therapy of Community Acquired Pneumonia in Children

Condition:   Pneumonia
Interventions:   Drug: Amoxicillin;   Drug: Amoxicillin-clavulanate;   Drug: Cefdinir;   Other: Placebo
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)

IMPROVinG Outcomes in Community Acquired Pneumonia

Condition:   Pneumonia
Interventions:   Other: New model of service delivery;   Other: Current practice
Sponsors:   Western Health, Australia;   University of Melbourne;   Monash University;   La Trobe University

Hospitalised Pneumonia With Extended Treatment (HOPE) Study

Condition:   Pneumonia
Interventions:   Drug: Amoxicillin-clavulanic Acid;   Drug: Placebo (for Amoxicillin-clavulanic Acid)
Sponsors:   Menzies School of Health Research;   Griffith University;   Sarawak General Hospital;   University of Malaya;   The University of Queensland;   Queensland University of Technology;   Nanyang Technological University

A Clinical Cohort Study of Pneumonia in Respiratory Intensive Care Unit

Condition:   Pneumonia
Intervention:   Other: pneumonia
Sponsor:   Beijing Chao Yang Hospital

Study to Compare Delafloxacin to Moxifloxacin for the Treatment of Adults With Community-acquired Bacterial Pneumonia

Condition:   Community Acquired Bacterial Pneumonia
Interventions:   Drug: Delafloxacin;   Drug: Moxifloxacin;   Drug: Linezolid
Sponsor:   Melinta Therapeutics, Inc.

Community-Acquired Pneumonia : Evaluation of Corticosteroids

Condition:   Community Acquired Pneumonia
Interventions:   Drug: Hydrocortisone;   Drug: Placebo
Sponsor:   University Hospital, Tours

Physiotherapy in Patients Hospitalized Due to Pneumonia.

Condition:   Pneumonia
Interventions:   Drug: cephalosporin with or without erythromycin;   Other: Physiotherapy program
Sponsor:   Universidad de Granada

A Retrospective Study on Hospitalized Patients With Community-acquired Pneumonia in China (CAP-China)

Condition:   Community Acquired Pneumonia
Intervention:   Other: other
Sponsors:   Capital Medical University;   Beijing Chao Yang Hospital;   Beijing Jishuitan Hospital;   Beijing Luhe Hospital;   Qingdao Municipal Hospital;   Qilu Hospital of Shandong University;   Beijing Huimin Hospital;   China-Japan Friendship Hospital;   Linzi Hospital;   Second Hospital of Beijing Armed Police Corps;   Kunming Yan'an Hospital
Unknown status

Trial on the Ideal Duration of Oral Antibiotics in Children With Pneumonia

Condition:   Pneumonia
Interventions:   Drug: Amoxicillin-Potassium Clavulanate Combination;   Drug: Placebo
Sponsors:   University of Malaya;   Menzies School of Health Research
Active, not recruiting

Diagnostic Value of Lung Ultrasound for Ventilator-Associated Pneumonia

Condition:   Ventilator-Associated Pneumonia
Intervention:   Other: Lung ultrasound examination
Sponsor:   Groupe Hospitalier Paris Saint Joseph

Tedizolid Phosphate (TR-701 FA) vs Linezolid for the Treatment of Nosocomial Pneumonia (MK-1986-002)

Condition:   Pneumonia
Interventions:   Drug: Tedizolid phosphate IV;   Drug: Linezolid
Sponsor:   Cubist Pharmaceuticals LLC

Clinical Characteristics and Microbiology of Healthcare Associated Pneumonia

Condition:   Healthcare Associated Pneumonia
Sponsor:   Far Eastern Memorial Hospital

Endotracheal Tubes for Prevention of Ventilator-associated Pneumonia

Condition:   Ventilator-acquired Pneumonia
Interventions:   Device: PVC ETT;   Device: PUC ETT;   Device: PUC-CASS ETT
Sponsors:   University of Washington;   National Heart, Lung, and Blood Institute (NHLBI)

Santeon-CAP; Dexamethasone in Community-acquired Pneumonia

Condition:   Community-acquired Pneumonia
Interventions:   Drug: Dexamethasone;   Drug: Placebo
Sponsors:   St. Antonius Hospital;   Canisius-Wilhelmina Hospital;   Onze Lieve Vrouw Hospital;   Catharina Ziekenhuis Eindhoven

Clinical Reassessment Versus Procalcitonin in Order to Shorten Antibiotic Duration in Community-acquired Pneumonia

Condition:   Community-acquired Pneumonia
Interventions:   Other: the clinical reassessment arm;   Other: the procalcitonin arm
Sponsor:   Nantes University Hospital

Duration of Antimicrobial Therapy for Paediatric Pneumonia

Condition:   Pneumonia
Intervention:   Drug: amoxicillin
Sponsor:   Hamilton Health Sciences Corporation

Pharmacodynamics Study of Imipenem in Patients With Ventilator Associated Pneumonia

Condition:   Ventilator Associated Pneumonia
Intervention:   Drug: Imipenem
Sponsors:   Prince of Songkla University;   Merck Sharp & Dohme Corp.

Bacterial Pneumonia Score (BPS) Guided Antibiotic Use in Children With Community Acquired Pneumonia

Condition:   Pneumonia
Interventions:   Behavioral: Strategy based on BPS guided antibiotic use;   Behavioral: Enforced Guidelines
Sponsor:   Hospital General de Niños Pedro de Elizalde

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