About Pneumonia Clinical Trials (Click to Open)

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Pneumonia Clinical TrialsGeneral Purpose

The lung inflammation that characterizes pneumonia is typically caused by a bacterial, viral, or fungal infection.

Furthermore, specific groups of individuals are more likely to develop pneumonia than others, including individuals over age 65 and those under the age of 2, as well as those who have pre-existing health problems, including heart failure, diabetes, and COPD.

In light of these known facts about pneumonia, research seeks to improve methods of preventing, diagnosing, and treating pneumonia.

What Will Pneumonia Clinical Trials Be Like?

When participating in a clinical trial for pneumonia, a few common tests and procedures may be involved; however, the ultimate design of the particular study will determine which specific procedures you will undergo.

On a basic level, you may be asked to provide a detailed history describing your symptoms, their duration, severity, and current or recent exposures (i.e., to people, animals, and travel). Your lungs will likely be examined by the study doctor through the use of a stethoscope.

In addition, you may have a chest x-ray to better visualize the infection in your lungs, or to monitor the progress of a specific treatment you are receiving for your pneumonia. Blood tests might also be involved to monitor signs of infection or your response to medications.

You may also be asked to provide a sputum/spit sample, undergo a CT scan (which is an x-ray like procedure that provides detailed images of areas inside your body), or undergo a procedure known as thoracentisis (the removal of fluid from the space between the outside lining of your lungs and the chest wall).

Your pulse and the amount of oxygen in your blood may also be measured, and you may be asked to undergo a bronchoscopy (a procedure in which your doctor inserts a flexible tube with a light on the end through your nose or mouth and into your airways).

Typical Pneumonia Clinical Trial Protocol:

Examples of pneumonia-related clinical trials might include the following:Pneumonia Clinical Trials

  • A study to determine if proactive treatment with antibiotics or antiviral medications in hospitalized patients with heart disease helps to prevent the development of pneumonia.
  • A study to determine the risk of pneumonia among individuals who smoke.
  • A study to determine the effectiveness of a newly-developed antibacterial or antiviral medication in treating pneumonia.
  • A study to determine the accuracy of a newly-developed diagnostic tool or imaging procedure to correctly diagnose the presence of pneumonia.
  • A study designed to determine the risk of developing pneumonia among individuals who received different types of breathing tubes during surgical procedures.

Suggested Search Terms:

“pneumonia children,” “pneumonia treatment,” “pneumonia bacteria,” “pneumonia virus,” “pneumonia COPD,” and “pneumonia surgery.”

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Early Mobilization of Patients With Community-acquired Pneumonia

Condition:   Pneumonia
Intervention:   Other: Historical control group for early mobilization
Sponsors:   Vendsyssel Hospital;   Hvidovre University Hospital

ePneumonia: Development of an Electronic Clinical Decision Support System for Community-Onset Pneumonia

Condition:   Pneumonia
Intervention:   Other: ePneumonia CDS
Sponsor:   Intermountain Health Care, Inc.
Not yet recruiting

Physiotherapy on Pneumonia in Childrens

Condition:   Pneumonia
Interventions:   Other: Rehabilitation;   Other: Chest physical therapy
Sponsors:   Universidade Metodista de Piracicaba;   Universidade do Estado do Pará

A Study of Streptococcus Pneumonia Colonisation and Invasive Disease in Cambodian Children

Condition:   Streptococcal Pneumonia
Interventions:   Other: Prospective study;   Other: Cross-sectional surveys
Sponsor:   University of Oxford

Description of Pneumococcal Pneumonia

Condition:   Community-acquired Pneumonia
Interventions:   Other: Signs of CAP and a positive chest X-Ray;   Other: Patients directly hospitalized;   Diagnostic Test: Control patients;   Other: Patients with partial participation;   Other: Signs of CAP and a negative chest X-Ray
Sponsor:   CNGE Conseil

Incidence of pNeumonia and Related ConseqUences in Nursing Home Residents

Condition:   Pneumonia
Intervention:   Other: Data collection on pneumonia events
Sponsor:   University Hospital, Toulouse

Multimometer - Vital Signs Device for Diagnosis of Pneumonia

Condition:   Pneumonia
Intervention:   Device: Multimometer
Sponsors:   University of Alberta;   Grand Challenges Canada

Validation of Thermal Imaging to Detect Pneumonia

Condition:   Pneumonia
Intervention:   Diagnostic Test: Thermal image
Sponsor:   Massachusetts General Hospital

Pneumonia Chart Review Cambodia

Condition:   Pneumonia
Sponsor:   University of Minnesota - Clinical and Translational Science Institute
Not yet recruiting

Managing Bacterial Pneumonia in Children Without Antimicrobials

Condition:   Pneumonia
Intervention:   Other: Multimodal Therapy
Sponsor:   ARCIM Institute Academic Research in Complementary and Integrative Medicine
Not yet recruiting

Screening for Pneumonia: A Comparison of Ultra Low Dose Chest CT [ULD-CT] and Conventional Chest Radiography [CXR]

Condition:   Pneumonia
Interventions:   Radiation: ULD-CT;   Radiation: CXR
Sponsor:   Maastricht University Medical Center

Twice Daily Treatment With Amoxicillin for Non-severe Community Acquired Pneumonia.

Condition:   Community-acquired Pneumonia
Intervention:   Drug: Amoxicillin
Sponsor:   St. Justine's Hospital

Diagnostic Use of Lung Ultrasound for Suspected Pneumonia in Nepal

Condition:   Pneumonia
Interventions:   Device: Lung Ultrasound;   Device: Chest X-ray;   Device: Chest Computed Tomography (CT)
Sponsors:   Patan Academy of Health Sciences;   Vanderbilt University;   Indiana University School of Medicine

Trial to Evaluate Beta-Lactam Antimicrobial Therapy of Community Acquired Pneumonia in Children

Condition:   Pneumonia
Interventions:   Drug: Amoxicillin;   Drug: Amoxicillin-clavulanate;   Drug: Cefdinir;   Other: Placebo
Sponsor:   National Institute of Allergy and Infectious Diseases (NIAID)

Community Case Management of Chest Indrawing Pneumonia

Condition:   Pneumonia
Intervention:   Drug: Oral amoxicillin for CI pneumonia
Sponsors:   Malaria Consortium;   World Health Organization

IMPROVinG Outcomes in Community Acquired Pneumonia

Condition:   Pneumonia
Interventions:   Other: New model of service delivery;   Other: Current practice
Sponsors:   Western Health, Australia;   University of Melbourne;   Monash University;   La Trobe University

International Study on NoSocomial Pneumonia in Intensive CaRE (PneumoINSPIRE)

Condition:   Nosocomial Pneumonia
Intervention:   Other: No intervention
Sponsors:   The University of Queensland;   European Society of Intensive Care Medicine

Hospitalised Pneumonia With Extended Treatment (HOPE) Study

Condition:   Pneumonia
Interventions:   Drug: Amoxicillin-clavulanic Acid;   Drug: Placebo (for Amoxicillin-clavulanic Acid)
Sponsors:   Menzies School of Health Research;   Griffith University;   Sarawak General Hospital;   University of Malaya;   The University of Queensland;   Queensland University of Technology;   Nanyang Technological University

A Clinical Cohort Study of Pneumonia in Respiratory Intensive Care Unit

Condition:   Pneumonia
Intervention:   Other: pneumonia
Sponsor:   Beijing Chao Yang Hospital

Study to Compare Delafloxacin to Moxifloxacin for the Treatment of Adults With Community-acquired Bacterial Pneumonia

Condition:   Community Acquired Bacterial Pneumonia
Interventions:   Drug: Delafloxacin;   Drug: Moxifloxacin;   Drug: Linezolid
Sponsor:   Melinta Therapeutics, Inc.

Community-Acquired Pneumonia : Evaluation of Corticosteroids

Condition:   Community Acquired Pneumonia
Interventions:   Drug: Hydrocortisone;   Drug: Placebo
Sponsor:   University Hospital, Tours

Diagnostic Value of Lung Ultrasound for Ventilator-Associated Pneumonia

Condition:   Ventilator-Associated Pneumonia
Intervention:   Other: Lung ultrasound examination
Sponsor:   Groupe Hospitalier Paris Saint Joseph

Tedizolid Phosphate (TR-701 FA) vs Linezolid for the Treatment of Nosocomial Pneumonia (MK-1986-002)

Condition:   Pneumonia
Interventions:   Drug: Tedizolid phosphate IV;   Drug: Linezolid
Sponsor:   Cubist Pharmaceuticals LLC

Endotracheal Tubes for Prevention of Ventilator-associated Pneumonia

Condition:   Ventilator-acquired Pneumonia
Interventions:   Device: PVC ETT;   Device: PUC ETT;   Device: PUC-CASS ETT
Sponsors:   University of Washington;   National Heart, Lung, and Blood Institute (NHLBI)

Clinical Reassessment Versus Procalcitonin in Order to Shorten Antibiotic Duration in Community-acquired Pneumonia

Condition:   Community-acquired Pneumonia
Interventions:   Other: the clinical reassessment arm;   Other: the procalcitonin arm
Sponsor:   Nantes University Hospital

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