Common Cold

Join Clinical Trials for Common Cold

Join Clinical Trials for Common Cold

General Purpose:

We’ve all had it at least once in our lives: the common cold. It’s not fun, leaves us feeling drained and dreary, and brings with it a multitude of ever-changing symptoms that rarely respond well to the most well-intentioned treatment.

Unfortunately, there is no cure for the common cold, due to the fact that over 200 different viruses can cause its symptoms to develop. However, a particular group of viruses, known as Rhinoviruses, cause between 30% and 50% of all colds.Therefore, research related to the Rhinoviruses is plentiful, and scientists have discovered a wealth of information about this group of viruses.

Due to this increased understanding, research related to the common cold often focuses on the development of new anti-viral drugs, the development and testing of new technologies to detect and analyze viruses in individuals who have cold-related symptoms, and studies designed to help people better manage the symptoms of this widespread problem.

Continued … Common Cold Clinical Trials (Click to Open)

Join Clinical Trials for Common Cold

Common Cold Clinical Trials

What Will Common Cold Clinical Trials Be like?

When participating in a clinical trial designed to investigate some aspect related to the common cold, a few common tests and procedures may be involved; however, the ultimate design of the particular study will determine which specific procedures you will undergo.

Documentation of symptoms will likely occur, as will monitoring of your symptoms’ severity and how long they persist. A physical examination may be required so that the study doctors can listen to your lungs, as well as feel and view your sinuses for signs of inflammation. A manual lymph node exam may also be performed, during with the doctor places his hands along the sides of your neck, below your ears, and along your throat to feel for swollen lymph nodes.

Sputum/spit samples, as well as blood samples, may also be taken. They may be analyzed to determine the virus causing the symptoms, as well as the types and levels of antibodies from your immune system that are presenting and fighting the infection.

Typical Common Cold Clinical Trial Protocol:

Current research related to the common cold is broad in scope and covers a wide range Common Cold Clinical Trialsof topics. Specific examples might include the following types of studies:

  • A study designed to investigate the effectiveness of a new medication designed to suppress coughing and reduce mucus production.
  • A study designed to determine the effectiveness of various behavioral interventions designed to help prevent the development of the common cold, including hand washing, sanitary sneezing practices, and the use of disinfectants in the home.
  • A trial designed to determine the effectiveness of alternative and natural therapies, such as Echinacea, vitamin C, and zinc in preventing the development of a cold, or shortening the duration of its symptoms.
  • A study designed to evaluate individual characteristics that might make an individual more susceptible to developing a cold, such as body weight, disease status (i.e., underlying diabetes, cystic fibrosis, asthma), age, environmental factors, and occupational exposures.

Suggested Search Terms:

“common cold treatment,” “common cold vitamin C,” “common cold zinc,” “common cold prevention,” and “common cold hygiene.”

Current Search Term:

“Common Cold”



Efficacy and Safety Study of Ingavirin® 90 mg Once Daily to Treat Influenza and Other Acute Viral Infections in Adults


Conditions:   Common Cold;   Influenza, Human;   Acute Respiratory Infection
Interventions:   Drug: Ingavirin;   Drug: Placebo
Sponsor:   Valenta Pharm JSC
Completed - verified May 2017


Efficacy and Safety of Regan Tangjiang for Treating the Common Cold With Wind-heat Syndrome


Condition:   Cold
Intervention:   Drug: Regan Tangjiang
Sponsor:   Beijing Da-an Bio-technology Co., Ltd.
Not yet recruiting - verified March 2017


Echinaforce Junior Bioavailability Trial


Condition:   Common Cold
Intervention:   Drug: Echinaforce junior
Sponsors:   Bioforce AG;   University Children's Hospital, Zurich
Recruiting - verified February 2017


To Evaluate the Efficacy and Safety of 1146A Nasal Spray in Adult Participants With Symptoms of Common Cold


Condition:   Common Cold
Interventions:   Drug: Carbomer 980 (1146A);   Other: Placebo
Sponsor:   GlaxoSmithKline
Recruiting - verified May 2017


PEAC: Phytus Efficacy in Acute Cough


Conditions:   Cough;   Common Cold
Intervention:   Drug: Phytus (Cisti, Thyme and Ivy Leaves)
Sponsor:   PharmEvo Pvt Ltd
Not yet recruiting - verified March 2017


Rapid Diagnostics for Upper Respiratory Infections in the Emergency Department


Conditions:   Respiratory Tract Infections;   Influenza, Human;   Common Cold
Intervention:   Device: Rapid respiratory pathogen nucleic acid amplification test
Sponsors:   University of California, Davis;   BioFire Diagnostics, LLC
Recruiting - verified December 2016


Local Nasal Tolerability and Safety Study of 1146A in Healthy Adult Participants


Condition:   Common Cold
Interventions:   Drug: Carbomer 980;   Other: Placebo
Sponsor:   GlaxoSmithKline
Completed - verified January 2017


Local IgE in Subjects With Allergic or Non-allergic Rhinitis


Condition:   Perennial Rhinitis
Intervention:   Other: Observation
Sponsor:   Johann Wolfgang Goethe University Hospital
Recruiting - verified May 2016


Desloratadine,Phenylephrine Hcl,Ibuprofen Compared to Placebo in Treatment of Symptoms Associated With Common Cold/Flu


Condition:   Cold
Interventions:   Drug: Desloratadine+Phenylephrine+Ibuprofen;   Drug: Placebo
Sponsor:   Ache Laboratorios Farmaceuticos S.A.
Not yet recruiting - verified February 2017


Warming Sensation and Tolerability Study of Acetylcysteine 2% Oral Solution for Productive Cough


Condition:   Common Cold
Intervention:   Drug: Acetylcystine
Sponsor:   GlaxoSmithKline
Completed - verified September 2016


Effect of Probiotic on Rhinovirus Induced Colds


Condition:   Common Cold
Interventions:   Biological: Bifidobacterium animalis subsp. lactis Bl-04;   Other: sucrose
Sponsors:   University of Virginia;   Danisco Sweeteners Oy
Enrolling by invitation - verified February 2016


Effect of OC459 on the Response to Rhinovirus Challenge in Asthma


Conditions:   Asthma;   Rhinovirus;   Picornaviridae Infections;   Common Cold
Interventions:   Drug: OC459;   Drug: Placebo;   Other: Rhinovirus
Sponsors:   Imperial College London;   Medical Research Council;   Atopix Therapeutics, Ltd.
Recruiting - verified August 2016


Efficacy and Safety Study of Ingavirin® to Treat Influenza and Other Acute Respiratory Viral Infections in Patients 3-6 y.o.


Conditions:   Common Cold;   Influenza
Interventions:   Drug: Imidazolyl ethanamide pentandioic acid;   Drug: placebo
Sponsors:   Valenta Pharm JSC;   Atlant Clinical Ltd.
Completed - verified February 2016


Nasal Swab Study to Explore the Nasal Microbia


Condition:   Common Cold
Intervention:  
Sponsor:   Kimberly-Clark Corporation
Completed - verified July 2016


Evaluation of ColdZyme® on Experimentally Induced Common Cold.


Condition:   Common Cold
Interventions:   Device: ColdZyme® mouth spray;   Device: Placebo
Sponsors:   Enzymatica AB;   Therapeutic Frontiers
Active, not recruiting - verified September 2016


Study to Evaluate the Efficacy of N-acetylcysteine (NAC) in the Treatment of the Common Cold and Cough


Condition:   Common Cold Associated With Cough
Interventions:   Drug: N-acetylcysteine;   Drug: Placebo
Sponsor:   Novartis
Completed - verified May 2016


The Effect of Paracetamol, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide and Chlorpheniramine Maleate Tablets Compared to Placebo in Subjects Suffering From the Common Cold or Influenza.


Condition:   Common Cold
Interventions:   Drug: Test tablet;   Other: Placebo
Sponsors:   GlaxoSmithKline;   Sino-American Tianjin Smith Kline & French Laboratories Ltd
Completed - verified May 2016


Safety and Intake Effect of EPs® 7630 (an Extract of the Roots of Pelargonium Sidoides)


Condition:   Common Cold
Interventions:   Drug: EPs® 7630;   Drug: Placebo
Sponsor:   Dr. Willmar Schwabe GmbH & Co. KG
Completed - verified January 2017


Real-life Management and Therapeutic Outcome of Patients With Chronic Rhinitis and Chronic Urticaria in Thailand


Conditions:   Allergic Rhinitis;   Non-allergic Rhinitis;   Chronic Urticaria
Intervention:  
Sponsor:   Chulalongkorn University
Recruiting - verified July 2016


Effect of Probiotic on the Innate and Adaptive Host Response to Rhinovirus (EPIARR)


Condition:   Common Cold
Interventions:   Dietary Supplement: Bifidobacterium lactis Bl-04;   Dietary Supplement: Placebo;   Biological: Rhinovirus
Sponsors:   University of Virginia;   DuPont Nutrition and Health
Completed - verified April 2017


Intranasal SB-705498 in Non-allergic Rhinitis Patients


Condition:   Rhinitis
Interventions:   Drug: Placebo;   Drug: SB-705498
Sponsor:   GlaxoSmithKline
Completed - verified November 2016


Study to Evaluate the Efficacy and Safety of Fixed Dose Combination of Diphenhydramine + Pseudoephedrine + Dropropizine in the Control of Cough and the Relief of Nasal Symptoms, Suffering From Non-productive Cough and Acute Rhinitis


Conditions:   Nasal Congestion;   Cough
Interventions:   Drug: Group 1;   Drug: Group 2
Sponsor:   Ache Laboratorios Farmaceuticos S.A.
Withdrawn - verified October 2016


Evaluation of Efficacy and Safety in Control Cough and the Relief of Nasal Symptoms in Children 2-12 Years Old,Suffering From Cough and Acute Rhinitis


Conditions:   Inflammation;   Cough;   Rhinitis
Interventions:   Drug: diphenhydramine + dropropizine + pseudoephedrine;   Drug: Dropropizine and fixed dose combination of pseudoephedrine hydrochloride + brompheniramine maleate (Dimetapp® elixir).
Sponsor:   Ache Laboratorios Farmaceuticos S.A.
Withdrawn - verified October 2016


Study Comparing 3 Formulations to Evaluate the Efficacy and Safety of the Inflammatory Symptoms of the Upper Respiratory Tract, in Children Between 2 and 6 Years Old


Condition:   Common Cold
Interventions:   Drug: Bronpheniramine and fenilefrine (Decongex Plus);   Drug: Bronpheniramine isolated;   Drug: Fenilefrine isolated
Sponsor:   Ache Laboratorios Farmaceuticos S.A.
Withdrawn - verified October 2016


The Natural History of Viral Upper Respiratory Infections in Children Aged 6 to Less Than 14 Years


Conditions:   Upper Respiratory Infection;   Common Cold
Intervention:  
Sponsors:   West Penn Allegheny Health System;   Allegheny Singer Research Institute;   Merck Sharp & Dohme Corp.
Completed - verified July 2016

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