Chronic Bronchitis

A Study of Andrographolide Sulfonate in Patients With Acute Exacerbation of Chronic Bronchitis

Condition:   Acute Exacerbation of Chronic Bronchitis
Interventions:   Drug: andrographolide sulfonate;   Drug: andrographolide sulfonate simulation
Sponsor:   Jiangxi Qingfeng Pharmaceutical Co. Ltd.
Recruiting - verified April 2017

Gala FIH Feasibility Study for the Treatment of Chronic Bronchitis

Condition:   Chronic Bronchitis
Intervention:   Device: Gala Airway Treatment System
Sponsor:   Gala Therapeutics, Inc.
Recruiting - verified April 2017

The Effectiveness of Roflumilast in Improving Mucociliary Clearance in Patients With COPD and Chronic Bronchitis

Conditions:   COPD;   Chronic Bronchitis;   Emphysema
Interventions:   Drug: Roflumilast;   Drug: Placebo
Sponsor:   Johns Hopkins University
Active, not recruiting - verified April 2017

The Topic Trial - Study to Determine the Safety and Efficacy of Ivacaftor

Conditions:   Chronic Obstructive Pulmonary Disease;   Chronic Bronchitis
Interventions:   Drug: Ivacaftor 150 MG;   Drug: Placebo
Sponsors:   University of Alabama at Birmingham;   National Heart, Lung, and Blood Institute (NHLBI);   Vertex Pharmaceuticals Incorporated
Recruiting - verified April 2017

Studying the Airway Microenvironment in Patients Undergoing Surgical and Bronchoscopic Interventions for COPD

Conditions:   Chronic Obstructive Pulmonary Disease;   Emphysema;   Chronic Bronchitis
Sponsor:   Royal Brompton & Harefield NHS Foundation Trust
Not yet recruiting - verified January 2017

Acute Dyspnea After Use of Non-invasive Ventilation in COPD and Emphysema (Deventilation Syndrome)

Condition:   Obstructive Chronic Bronchitis
Sponsor:   Felix JF Herth
Not yet recruiting - verified October 2016

Activity Monitor Use in COPD Patients Undergoing Rehabilitation

Conditions:   Chronic Obstructive Pulmonary Disease;   COPD;   Emphysema;   Chronic Bronchitis
Intervention:   Behavioral: Feedback
Sponsor:   Salford Royal NHS Foundation Trust
Recruiting - verified September 2016

Long-term Use of Spiolto Respimat in Japanese Patients With Chronic Obstructive Pulmonary Disease

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Spiolto
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2017

The Relationship Between GOLD Risk Group and Clinical Outcomes in a Community-based COPD Cohort

Conditions:   Chronic Obstructive Pulmonary Disease (COPD);   Emphysema;   Chronic Bronchitis
Sponsors:   Duke University;   Boehringer Ingelheim
Recruiting - verified April 2017

COPD Patient-Powered Research Network

Conditions:   Chronic Obstructive Pulmonary Disorder;   Chronic Obstructive Lung Disease;   Emphysema;   Chronic Bronchitis
Intervention:   Other: Patient Reported Outcomes
Sponsors:   COPD Foundation;   Kaiser Foundation Hospitals, Center for Health Research
Recruiting - verified June 2016

Clinical & Systems Medicine Investigations of Smoking-related Chronic Obstructive Pulmonary Disease

Conditions:   Chronic Obstructive Pulmonary Disease;   Emphysema;   Chronic Bronchitis;   Chronic Airways Obstruction;   Smoking
Sponsors:   Karolinska Institutet;   University of California, San Francisco;   Göteborg University;   University of Bergen;   University of Oulu;   Kyoto University;   Swedish Heart Lung Foundation;   The Swedish Research Council;   Stockholm County Council, Sweden;   Vinnova;   Swedish Foundation for Strategic Research (SSF);   European Union
Active, not recruiting - verified January 2017

Safety and Feasibility Study of Rejuvenair™ for Treating Chronic Bronchitis Patients

Conditions:   Bronchitis, Chronic;   Cryotherapy Effect
Intervention:   Device: RejuvenAir
Sponsor:   CSA Medical, Inc.
Recruiting - verified May 2017

Effect of Losartan on Airway Mucociliary Dysfunction in Patients With COPD and Chronic Bronchitis

Conditions:   COPD;   Chronic Bronchitis
Interventions:   Drug: Losartan 50 mg;   Drug: losartan 100 mg
Sponsor:   University of Miami
Recruiting - verified February 2017

Epidemiology of Chronic Bronchitis in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Conditions:   Chronic Obstructive Pulmonary Disease;   Chronic Bronchitis
Sponsor:   AstraZeneca
Completed - verified September 2016

Respiratory Therapy in COPD Exacerbations

Condition:   Obstructive Chronic Bronchitis With Acute Exacerbation
Interventions:   Other: No Respiratory Therapy;   Other: Respiratory Therapy
Sponsor:   Parc de Salut Mar
Completed - verified April 2015

The Effect of Physical Activity Promotion on Short and Long-term Outcomes in COPD

Conditions:   COPD;   Emphysema;   Chronic Bronchitis
Intervention:   Behavioral: Pedometer and Website
Sponsor:   VA Office of Research and Development
Recruiting - verified March 2017

Mindfulness-based Cognitive Therapy for Chronic Obstructive Pulmonary Disease

Conditions:   Chronic Obstructive Pulmonary Disease (COPD);   Chronic Obstructive Lung Disease;   Chronic Obstructive Airway Disease;   Chronic Bronchitis;   Emphysema
Interventions:   Behavioral: Mindfulness-based cognitive therapy;   Behavioral: Pulmonary rehabilitation
Sponsors:   University of Aarhus;   Aarhus University Hospital
Completed - verified June 2014

Study of COPD Subgroups and Biomarkers

Conditions:   COPD;   Chronic Obstructive Pulmonary Disease;   Chronic Bronchitis;   Emphysema
Sponsors:   University of North Carolina, Chapel Hill;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified January 2017

BI 113608 Administered as Tablets Twice Daily Over 4 Weeks in Patients With Chronic Obstructive Pulmonary Disease Associated With Chronic Bronchitis

Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Placebo to BI 113608 high dose b.i.d.;   Drug: Placebo to BI 113608 low dose b.i.d.;   Drug: BI 113608 high dose b.i.d.;   Drug: Placebo to BI 113608 medium dose b.i.d.;   Drug: BI 113608 low dose b.i.d.;   Drug: BI 113608 medium dose b.i.d.
Sponsor:   Boehringer Ingelheim
Completed - verified November 2016

The Natural History of Gene Expression in the Lung Cells of Non-Smokers, Smokers and Ex-Smokers in Health and Disease

Conditions:   Chronic Obstructive Pulmonary Disease (COPD);   Smoking;   Smoking Cessation;   Chronic Bronchitis;   Emphysema
Sponsor:   Weill Medical College of Cornell University
Active, not recruiting - verified May 2017

Efficacy of Losartan in Preventing Progression of COPD

Conditions:   COPD;   Emphysema;   Chronic Bronchitis;   Smoking
Interventions:   Drug: Losartan;   Drug: Placebo
Sponsors:   Johns Hopkins University;   National Heart, Lung, and Blood Institute (NHLBI);   Merck Sharp & Dohme Corp.
Completed - verified March 2017

Perforomist Versus Foradil Evaluated by Inspiratory Capacity and High Resolution Computed Tomography (HRCT)

Conditions:   Chronic Obstructive Pulmonary Disease;   COPD;   Chronic Bronchitis;   Emphysema
Intervention:   Drug: formoterol fumarate
Sponsors:   University of California, Los Angeles;   Dey, L.P.
Withdrawn - verified August 2016

Dietary and Genetic Factors in Asthma & Chronic Bronchitis in a Cohort of Chinese Singaporeans

Conditions:   Chronic Bronchitis;   Asthma
Sponsor:   National Institute of Environmental Health Sciences (NIEHS)
Completed - verified April 12, 2012

GW815SF For Chronic Obstructive Pulmonary Disease (Chronic Bronchitis, Emphysema)

Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: fluticasone propionate/salmeterol combination DISKUS
Sponsor:   GlaxoSmithKline
Completed - verified March 2017

Evaluating Genes in Sputum to Measure Drug Response in COPD

Conditions:   Chronic Obstructive Pulmonary Disease (COPD);   Emphysema;   Chronic Bronchitis
Intervention:   Drug: Salmeterol or Salmeterol/Fluticasone
Sponsors:   National Jewish Health;   GlaxoSmithKline
Terminated - verified March 2017

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