Chronic Bronchitis



A Study of Andrographolide Sulfonate in Patients With Acute Exacerbation of Chronic Bronchitis


Condition:   Acute Exacerbation of Chronic Bronchitis
Interventions:   Drug: andrographolide sulfonate;   Drug: andrographolide sulfonate simulation
Sponsor:   Jiangxi Qingfeng Pharmaceutical Co. Ltd.
Recruiting - verified April 2017


Gala FIH Feasibility Study for the Treatment of Chronic Bronchitis


Condition:   Chronic Bronchitis
Intervention:   Device: Gala Airway Treatment System
Sponsor:   Gala Therapeutics, Inc.
Recruiting - verified April 2017


The Effectiveness of Roflumilast in Improving Mucociliary Clearance in Patients With COPD and Chronic Bronchitis


Conditions:   COPD;   Chronic Bronchitis;   Emphysema
Interventions:   Drug: Roflumilast;   Drug: Placebo
Sponsor:   Johns Hopkins University
Active, not recruiting - verified April 2017


The Topic Trial - Study to Determine the Safety and Efficacy of Ivacaftor


Conditions:   Chronic Obstructive Pulmonary Disease;   Chronic Bronchitis
Interventions:   Drug: Ivacaftor 150 MG;   Drug: Placebo
Sponsors:   University of Alabama at Birmingham;   National Heart, Lung, and Blood Institute (NHLBI);   Vertex Pharmaceuticals Incorporated
Recruiting - verified April 2017


Studying the Airway Microenvironment in Patients Undergoing Surgical and Bronchoscopic Interventions for COPD


Conditions:   Chronic Obstructive Pulmonary Disease;   Emphysema;   Chronic Bronchitis
Intervention:  
Sponsor:   Royal Brompton & Harefield NHS Foundation Trust
Not yet recruiting - verified January 2017


Acute Dyspnea After Use of Non-invasive Ventilation in COPD and Emphysema (Deventilation Syndrome)


Condition:   Obstructive Chronic Bronchitis
Intervention:  
Sponsor:   Felix JF Herth
Not yet recruiting - verified October 2016


Activity Monitor Use in COPD Patients Undergoing Rehabilitation


Conditions:   Chronic Obstructive Pulmonary Disease;   COPD;   Emphysema;   Chronic Bronchitis
Intervention:   Behavioral: Feedback
Sponsor:   Salford Royal NHS Foundation Trust
Recruiting - verified September 2016


Long-term Use of Spiolto Respimat in Japanese Patients With Chronic Obstructive Pulmonary Disease


Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: Spiolto
Sponsor:   Boehringer Ingelheim
Recruiting - verified May 2017


The Relationship Between GOLD Risk Group and Clinical Outcomes in a Community-based COPD Cohort


Conditions:   Chronic Obstructive Pulmonary Disease (COPD);   Emphysema;   Chronic Bronchitis
Intervention:  
Sponsors:   Duke University;   Boehringer Ingelheim
Recruiting - verified April 2017


COPD Patient-Powered Research Network


Conditions:   Chronic Obstructive Pulmonary Disorder;   Chronic Obstructive Lung Disease;   Emphysema;   Chronic Bronchitis
Intervention:   Other: Patient Reported Outcomes
Sponsors:   COPD Foundation;   Kaiser Foundation Hospitals, Center for Health Research
Recruiting - verified June 2016


Clinical & Systems Medicine Investigations of Smoking-related Chronic Obstructive Pulmonary Disease


Conditions:   Chronic Obstructive Pulmonary Disease;   Emphysema;   Chronic Bronchitis;   Chronic Airways Obstruction;   Smoking
Intervention:  
Sponsors:   Karolinska Institutet;   University of California, San Francisco;   Göteborg University;   University of Bergen;   University of Oulu;   Kyoto University;   Swedish Heart Lung Foundation;   The Swedish Research Council;   Stockholm County Council, Sweden;   Vinnova;   Swedish Foundation for Strategic Research (SSF);   European Union
Active, not recruiting - verified January 2017


Safety and Feasibility Study of Rejuvenair™ for Treating Chronic Bronchitis Patients


Conditions:   Bronchitis, Chronic;   Cryotherapy Effect
Intervention:   Device: RejuvenAir
Sponsor:   CSA Medical, Inc.
Recruiting - verified May 2017


Effect of Losartan on Airway Mucociliary Dysfunction in Patients With COPD and Chronic Bronchitis


Conditions:   COPD;   Chronic Bronchitis
Interventions:   Drug: Losartan 50 mg;   Drug: losartan 100 mg
Sponsor:   University of Miami
Recruiting - verified February 2017


Epidemiology of Chronic Bronchitis in Patients With Chronic Obstructive Pulmonary Disease (COPD)


Conditions:   Chronic Obstructive Pulmonary Disease;   Chronic Bronchitis
Intervention:  
Sponsor:   AstraZeneca
Completed - verified September 2016


Respiratory Therapy in COPD Exacerbations


Condition:   Obstructive Chronic Bronchitis With Acute Exacerbation
Interventions:   Other: No Respiratory Therapy;   Other: Respiratory Therapy
Sponsor:   Parc de Salut Mar
Completed - verified April 2015


The Effect of Physical Activity Promotion on Short and Long-term Outcomes in COPD


Conditions:   COPD;   Emphysema;   Chronic Bronchitis
Intervention:   Behavioral: Pedometer and Website
Sponsor:   VA Office of Research and Development
Recruiting - verified March 2017


Mindfulness-based Cognitive Therapy for Chronic Obstructive Pulmonary Disease


Conditions:   Chronic Obstructive Pulmonary Disease (COPD);   Chronic Obstructive Lung Disease;   Chronic Obstructive Airway Disease;   Chronic Bronchitis;   Emphysema
Interventions:   Behavioral: Mindfulness-based cognitive therapy;   Behavioral: Pulmonary rehabilitation
Sponsors:   University of Aarhus;   Aarhus University Hospital
Completed - verified June 2014


Study of COPD Subgroups and Biomarkers


Conditions:   COPD;   Chronic Obstructive Pulmonary Disease;   Chronic Bronchitis;   Emphysema
Intervention:  
Sponsors:   University of North Carolina, Chapel Hill;   National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting - verified January 2017


BI 113608 Administered as Tablets Twice Daily Over 4 Weeks in Patients With Chronic Obstructive Pulmonary Disease Associated With Chronic Bronchitis


Condition:   Pulmonary Disease, Chronic Obstructive
Interventions:   Drug: Placebo to BI 113608 high dose b.i.d.;   Drug: Placebo to BI 113608 low dose b.i.d.;   Drug: BI 113608 high dose b.i.d.;   Drug: Placebo to BI 113608 medium dose b.i.d.;   Drug: BI 113608 low dose b.i.d.;   Drug: BI 113608 medium dose b.i.d.
Sponsor:   Boehringer Ingelheim
Completed - verified November 2016


The Natural History of Gene Expression in the Lung Cells of Non-Smokers, Smokers and Ex-Smokers in Health and Disease


Conditions:   Chronic Obstructive Pulmonary Disease (COPD);   Smoking;   Smoking Cessation;   Chronic Bronchitis;   Emphysema
Intervention:  
Sponsor:   Weill Medical College of Cornell University
Active, not recruiting - verified May 2017


Efficacy of Losartan in Preventing Progression of COPD


Conditions:   COPD;   Emphysema;   Chronic Bronchitis;   Smoking
Interventions:   Drug: Losartan;   Drug: Placebo
Sponsors:   Johns Hopkins University;   National Heart, Lung, and Blood Institute (NHLBI);   Merck Sharp & Dohme Corp.
Completed - verified March 2017


Perforomist Versus Foradil Evaluated by Inspiratory Capacity and High Resolution Computed Tomography (HRCT)


Conditions:   Chronic Obstructive Pulmonary Disease;   COPD;   Chronic Bronchitis;   Emphysema
Intervention:   Drug: formoterol fumarate
Sponsors:   University of California, Los Angeles;   Dey, L.P.
Withdrawn - verified August 2016


Dietary and Genetic Factors in Asthma & Chronic Bronchitis in a Cohort of Chinese Singaporeans


Conditions:   Chronic Bronchitis;   Asthma
Intervention:  
Sponsor:   National Institute of Environmental Health Sciences (NIEHS)
Completed - verified April 12, 2012


GW815SF For Chronic Obstructive Pulmonary Disease (Chronic Bronchitis, Emphysema)


Condition:   Pulmonary Disease, Chronic Obstructive
Intervention:   Drug: fluticasone propionate/salmeterol combination DISKUS
Sponsor:   GlaxoSmithKline
Completed - verified March 2017


Evaluating Genes in Sputum to Measure Drug Response in COPD


Conditions:   Chronic Obstructive Pulmonary Disease (COPD);   Emphysema;   Chronic Bronchitis
Intervention:   Drug: Salmeterol or Salmeterol/Fluticasone
Sponsors:   National Jewish Health;   GlaxoSmithKline
Terminated - verified March 2017

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