Bronchiectasis

Join Clinical Trials for Bronciectasis

Join Clinical Trials for Bronchiectasis

General Purpose The serious, repetitive lung infections associated with bronchiectasis can be scary for those who are affected by this damaging lung disease. Unfortunately, each lung infection that occurs increases the amount of damage to the lungs, which further increases the risk of major damage to vital organs, including the heart.

As one who suffers from this devastating condition, you may be looking for new and improved approaches to manage your disease.

Fortunately, there is much ongoing research that is designed to help people just like you.

Such research might investigate the role of environmental factors, genetics, and newly developed antibiotic therapies. Other studies may be exploring new respiratory therapies that can help improve symptoms.

Continued … Bronchiectasis Clinical Trials (Click to Open)

Join Clinical Trials for Bronchiectasis

Clinical Trials for Bronchiectasis

What Will Clinical Trials forBronchiectasis Be like?

When participating in a clinical trial designed to investigate some aspect related to bronchiectasis, a few common tests and procedures may be involved; however, the ultimate design of the particular study will determine which specific procedures you will undergo.

You will most likely undergo a computed tomography scan (CT, or “CAT” scan) of the chest. CT scans are the most common test used to diagnose bronchiectasis and for determining the extent and location of the damage it causes to the lungs. CT scans are high-tech imaging procedures that provide detailed pictures of areas inside the body, much like an x-ray.

You may also undergo a chest x-ray as well, which can help to reveal or monitor heart damage. In addition, you may also undergo any one or a combination of the following tests: blood tests to detect or monitor infections; sputum (spit/phlegm) culture to detect the presence of bacteria or fungi in your lungs; lung function tests; and tests to detect the presence of cystic fibrosis.

You may also undergo a bronchoscopy, which is a procedure in which your doctor inserts a flexible tube with a light on the end through your nose or mouth and into your airways. This helps your doctor to see the inside of your airways and any damage that is present.

Typical Bronchiectasis Clinical Trial Protocol:

Current research regarding bronchiectasis spans a wide range of topics. Specific Clinical Trials for Bronchiectasisexamples might include the following types of studies:

  • Investigating the role of physical activity in managing bronchiectasis and improving lung function.
  • Evaluating the use of long-term antibiotic therapy as a maintenance strategy for bronchiectasis.
  • A trial comparing traditional respiratory therapies with newly developed respiratory therapy technologies to see which is better at improving the symptoms associated with bronchiectasis.
  • A trial investigating a newly developed antibiotic and its effectiveness in treating various bacteria that cause bronchiectasis to develop.
  • Studies comparing the genetic profiles of bronchiectasis patients to determine if particular genetic mutations make one person more likely than another to develop the condition.

Suggested Search Terms:

“bronchiectasis treatment,” “bronchiectasis children,” “bronchiectasis cystic fibrosis,” “bronchiectasis antibiotics,” “bronchiectasis physical activity,” “bronchiectasis exercise,” and “bronchiectasis surgery.”

Current Search Term:

Bronchiectasis



Different Phenotypes of Bronchiectasis


Condition:   Bronchiectasis
Intervention:   Combination Product: Pulmonary function tests,Bronchiectasis severity index score
Sponsor:   Assiut University
Not yet recruiting


Assessment of INS1007 in Subjects With Non-Cystic Fibrosis Bronchiectasis


Condition:   Non-Cystic Fibrosis Bronchiectasis
Interventions:   Drug: INS1007 10 mg oral tablet;   Drug: INS1007 25 mg oral tablet;   Drug: Placebo Oral Tablet
Sponsor:   Insmed Incorporated
Not yet recruiting


Exercise Capacity in Patients With Cystic Fibrosis vs. Non-cystic Fibrosis Bronchiectasis


Condition:   Bronchiectasis
Intervention:  
Sponsor:   Rambam Health Care Campus
Recruiting


Characterization of Airway Mucus in Bronchiectasis Patients and Healthy Controls


Condition:   Bronchiectasis Adult
Intervention:  
Sponsor:   University of North Carolina, Chapel Hill
Completed


Oscillating PEP vs Autogenic Drainage in People With Bronchiectasis


Condition:   Bronchiectasis
Interventions:   Device: oPEP;   Behavioral: Autogenic drainage
Sponsors:   Carmel Medical Center;   Rambam Health Care Campus
Recruiting


Pulmonary Rehabilitation in Non-Cystic Fibrosis Bronchiectasis


Condition:   Bronchiectasis
Interventions:   Other: Pulmonary Rehabilitation;   Other: Control
Sponsor:   University of Sao Paulo
Recruiting


Cardiovascular Comorbidities and Bronchiectasis


Condition:   Bronchiectasis
Intervention:  
Sponsor:   Centre Hospitalier Intercommunal Creteil
Recruiting


Short-and Long-term Effects of a Home-based Rehabilitation Program in Patients With Bronchiectasis


Condition:   Bronchiectasis
Interventions:   Other: Training Group;   Other: Control Group
Sponsors:   University of Nove de Julho;   University of Sao Paulo
Recruiting


Autologous Bronchial Basal Cells Transplantation for Treatment of Bronchiectasis


Condition:   Bronchiectasis
Intervention:   Biological: Bronchial basal cells
Sponsors:   Regend Therapeutics;   Southwest Hospital, China;   Tongji University
Recruiting


Comparative Effectiveness and Safety of Inhaled Corticosteroids and Antimicrobial Compounds for Non-CF Bronchiectasis


Condition:   Bronchiectasis
Interventions:   Drug: inhaled corticosteroid therapy;   Drug: macrolide therapy
Sponsors:   Oregon Health and Science University;   Patient-Centered Outcomes Research Institute;   University of Alabama at Birmingham;   National Jewish Health;   COPD Foundation
Active, not recruiting


Inhaled Nebulized Tobramycin in Non-cystic Fibrosis Bronchiectasis


Condition:   Non-CF Bronchiectasis
Interventions:   Drug: tobramycin inhalation solution;   Drug: Saline 0.9% inhalation solution
Sponsor:   Medical Center Alkmaar
Recruiting


Safety and Potential Efficacy of Human Mesenchymal Stem Cells in Non‐Cystic Fibrosis Bronchiectasis


Condition:   Bronchiectasis
Intervention:   Biological: hMSCs
Sponsor:   Marilyn Glassberg
Recruiting


Prognosis of Bronchiectasis in Children--A Multicenter Prospective Cohort Study


Condition:   Bronchiectasis
Intervention:  
Sponsors:   Baoping XU;   Wuhan women and children's health care center;   Children's Hospital of Chongqing Medical University;   Yuying Children's Hospital of Wenzhou Medical University;   Children's Hospital of Changchun;   Shenzhen Children's Hospital;   Jiangxi Province Children's Hospital;   Shanghai Children's Medical Center;   First Affiliated Hospital of Guangxi Medical University;   Tianjin Children's Hospital;   The First Affiliated Hospital of Xiamen University;   Children's Hospital of Fudan University;   The Affiliated Hospital Of Guizhou Medical University;   Shanxi Children's Hospital
Recruiting


Aetiology of Children With Bronchiectasis in China


Condition:   Bronchiectasis
Intervention:  
Sponsors:   Beijing Children's Hospital;   Wuhan women and children's health care center;   Children's Hospital of Chongqing Medical University;   Yuying Children's Hospital of Wenzhou Medical University;   Children's Hospital of Changchun;   Shenzhen Children's Hospital;   Jiangxi Province Children's Hospital;   Shanghai Children's Medical Center;   First Affiliated Hospital of Guangxi Medical University;   Tianjin Children's Hospital;   The First Affiliated Hospital of Xiamen University;   The Affiliated Hospital Of Guizhou Medical University;   Shanxi Children's Hospital
Recruiting


Acute Effects of a Flutter Device and Chest Wall Compression on Respiratory System Impedance in Bronchiectasis Patients


Condition:   Bronchiectasis
Interventions:   Device: Flutter;   Other: Chest Compression;   Other: Control;   Other: Impulse Oscillometric;   Other: Dyspnea scale;   Other: Acceptability and tolerance;   Device: Pulse oximetry;   Other: Difficulty sputum
Sponsor:   University of Sao Paulo
Completed


Clinimetric Properties of Outcome Measures in Bronchiectasis in the UK


Condition:   Bronchiectasis
Intervention:  
Sponsors:   Queen's University, Belfast;   Belfast Health and Social Care Trust;   South Eastern Health and Social Care Trust;   Royal Brompton & Harefield NHS Foundation Trust;   NHS Lothian;   Papworth Hospital NHS Foundation Trust;   NHS Tayside;   University Hospital Southampton NHS Foundation Trust;   Cardiff and Vale University Health Board;   Medical Research Council
Recruiting


Sputum Clearance Effects of Hypertonic Saline in Non-cystic Fibrosis Bronchiectasis


Condition:   Bronchiectasis
Interventions:   Other: Hypertonic saline solution;   Other: Hyaneb solution;   Other: Isotonic saline solution
Sponsor:   Hospital Clinic of Barcelona
Completed


Long-term Airway Clearance Therapy in Non-cystic Fibrosis Bronchiectasis


Condition:   Bronchiectasis
Intervention:   Other: Chest physiotherapy plus usual care
Sponsors:   Universidad San Jorge;   Hospital Clinic of Barcelona
Enrolling by invitation


Ciprofloxacin Dry Powder for Inhalation (DPI) in Non-cystic Fibrosis Bronchiectasis (Non-CF BE)


Condition:   Bronchiectasis
Interventions:   Drug: Ciprofloxacin (BAYQ3939) dry powder for inhalation;   Drug: Placebo
Sponsors:   Bayer;   Novartis
Completed


Phase 3 Study With Dual Release Ciprofloxacin for Inhalation in Non-CF Bronchiectasis


Condition:   Non Cystic Fibrosis Bronchiectasis
Interventions:   Drug: Pulmaquin;   Drug: Placebo
Sponsors:   Aradigm Corporation;   Grifols Therapeutics Inc.
Completed


Bacterial Load Guided Therapy for Severe Bronchiectasis Exacerbations


Condition:   Bronchiectasis
Interventions:   Other: Duration;   Drug: Colomycin;   Drug: Meropenem
Sponsors:   University of Edinburgh;   NHS Lothian
Recruiting


Prevention of OM-85 on Bronchiectasis Exacerbation


Condition:   Bronchiectasis With Acute Exacerbation
Intervention:   Drug: OM-85
Sponsors:   Chinese Academy of Medical Sciences;   Peking University;   Capital Medical University;   Tianjin Medical University;   Zhejiang University;   China Medical University, China;   Tongji University
Recruiting


Ciprofloxacin Dry Powder for Inhalation in Non-cystic Fibrosis Bronchiectasis (Non-CF BE)


Condition:   Bronchiectasis
Interventions:   Drug: Ciprofloxacin DPI (BAYQ3939);   Drug: Placebo
Sponsors:   Bayer;   Novartis
Completed


Phase 3 Study With Dual Release Ciprofloxacin for Inhalation in Non-CF Bronchiectasis


Condition:   Non Cystic Fibrosis Bronchiectasis
Intervention:   Drug: Ciprofloxacin
Sponsors:   Aradigm Corporation;   Grifols Therapeutics Inc.
Completed


Atorvastatin in Bronchiectasis in Patients With Pseudomonas Aeruginosa


Condition:   BRONCHIECTASIS
Intervention:   Drug: ATORVASTATIN
Sponsors:   University of Edinburgh;   NHS Lothian
Completed

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