Prader-Willi Syndrome



A Study of GLWL-01 in Patients With Prader-Willi Syndrome


Condition:   Prader-Willi Syndrome
Interventions:   Drug: GLWL-01;   Drug: Placebo
Sponsor:   GLWL Research Inc.
Not yet recruiting


B. Lactis B94 Effects of Gastrointestinal Function


Condition:   Quality of Life
Interventions:   Dietary Supplement: B. lactis B94;   Dietary Supplement: Placebo
Sponsors:   University of Florida;   Lallemand Health Solutions
Not yet recruiting


Intranasal Oxytocin for Infants With Prader-Willi Syndrome


Condition:   Prader-Willi Syndrome
Interventions:   Drug: Oxytocin;   Drug: Placebo
Sponsor:   University of Florida
Recruiting


Intranasal Oxytocin vs. Placebo for the Treatment of Hyperphagia in Prader-Willi Syndrome


Conditions:   Prader-Willi Syndrome;   Hyperphagia
Interventions:   Drug: Intranasal Oxytocin (IN-OXT);   Drug: Matched Placebo
Sponsors:   Montefiore Medical Center;   FDA Office of Orphan Products Development
Not yet recruiting


Co-administration of Tesofensine/Metoprolol in Subjects With Prader-Willi Syndrome (PWS)


Condition:   Confirmed Genetic Diagnosis of Prader-Willi Syndrome
Interventions:   Drug: Tesofensine/Metoprolol;   Drug: Placebos
Sponsor:   Saniona
Recruiting


Oxytocin Intranasal Administrations in Children With Prader-Willi Syndrome Aged From 3 to 12 Years


Condition:   Prader-Willi Syndrome
Interventions:   Drug: Oxytocin;   Drug: Placebo
Sponsor:   University Hospital, Toulouse
Recruiting


Optimizing the Social Engagement System in Prader-Willi Syndrome: Insights From the Polyvagal Theory


Condition:   Prader-Willi Syndrome
Intervention:   Behavioral: Listening Project Protocol
Sponsors:   Indiana University;   Latham Centers
Recruiting


Follow-up of Prader Willi Syndrome Infants Treated by Oxytocin and Comparison With Not-treated Infants.


Condition:   Prader-Willi Syndrome
Interventions:   Drug: Oxytocin;   Other: Control
Sponsor:   University Hospital, Toulouse
Recruiting


Oxygen Versus Medical Air for Treatment of CSA in Prader Will Syndrome


Conditions:   Sleep Apnea, Central;   Prader-Willi Syndrome
Intervention:   Biological: Medical Air vs Oxygen
Sponsor:   The Hospital for Sick Children
Recruiting


Cannabidiol Oral Solution for The Treatment of Subjects With Prader-Willi Syndrome


Condition:   Prader-Willi Syndrome
Interventions:   Drug: Cannabidiol;   Drug: Placebo
Sponsor:   INSYS Therapeutics Inc
Not yet recruiting


Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome


Conditions:   Prader-Willi Syndrome;   Hyperphagia
Interventions:   Drug: Intranasal Oxytocin (IN-OXT);   Drug: Matched Placebo
Sponsors:   Montefiore Medical Center;   Foundation for Prader-Willi Research
Active, not recruiting


Effect of Liraglutide for Weight Management in Paediatric Subjects With Prader-Willi Syndrome


Conditions:   Metabolism and Nutrition Disorder;   Obesity
Interventions:   Drug: liraglutide;   Drug: placebo
Sponsor:   Novo Nordisk A/S
Recruiting


SNP-based Microdeletion and Aneuploidy RegisTry (SMART)


Conditions:   22q11 Deletion Syndrome;   DiGeorge Syndrome;   Trisomy 21;   Trisomy 18;   Trisomy 13;   Monosomy X;   Sex Chromosome Abnormalities;   Cri-du-Chat Syndrome;   Angelman Syndrome;   Prader-Willi Syndrome;   1p36 Deletion Syndrome
Intervention:  
Sponsors:   Natera, Inc.;   George Washington University;   University of California, San Francisco;   Montefiore Medical Center;   Children's Hospital of Philadelphia
Recruiting


Ph 2 Trial to Evaluate Safety & Efficacy of RM-493 in Obese Patients With Prader-Willi Syndrome


Condition:   Prader-Willi Syndrome
Interventions:   Drug: RM-493;   Drug: Placebo
Sponsor:   Rhythm Pharmaceuticals, Inc.
Completed


Evaluation of Tolerance, Suckling and Food Intake After Repeated Nasals Administrations of Oxytocin in PWS Infants


Condition:   Prader Willi Syndrome
Intervention:   Drug: oxytocin
Sponsor:   University Hospital, Toulouse
Completed


Double-Blind, Placebo Controlled, Phase 3 Trial of ZGN-440 (Beloranib) in Obese Subjects With Prader-Willi Syndrome


Conditions:   Prader-Willi Syndrome;   Obesity
Interventions:   Drug: ZGN-440 for Injectable Suspension;   Drug: ZGN-440 Placebo for Injectable Suspension
Sponsor:   Zafgen, Inc.
Terminated


Oxytocin Trial in Prader-Willi Syndrome


Condition:   Prader Willi Syndrome
Interventions:   Drug: Intranasal oxytocin;   Other: Placebo
Sponsors:   University of Florida;   National Institutes of Health (NIH)
Completed


Prader-Willi Syndrome Macronutrient Study


Conditions:   Prader Willi Syndrome;   Syndromic Obesity;   Childhood Obesity
Interventions:   Other: Low Carbohydrate diet;   Other: Low Fat diet
Sponsors:   Duke University;   Foundation for Prader-Willi Research
Completed


Tolerance of Intranasal Administration of OT in Prader-Willi Newborn Babies


Condition:   Prader-Willi Syndrome
Intervention:   Drug: Oxytocin
Sponsor:   University Hospital, Toulouse
Completed


Brain-Derived Neurotrophic Factor in Obesity and Brain Function


Conditions:   Obesity;   Genetic Disorder;   Mental Retardation;   Developmental Delay
Intervention:  
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Completed


Bioequivalence of Two Somatropin Products (Norditropin® Versus Genotropin®) in Healthy Adult Volunteers


Conditions:   Genetic Disorder;   Prader-Willi Syndrome;   Growth Disorder;   Idiopathic Short Stature;   Healthy
Intervention:   Drug: somatropin
Sponsor:   Novo Nordisk A/S
Completed


Comparative Study Between Prader-Willi Patients Who Take Oxytocin Versus Placebo


Condition:   Prader Willi Syndrome
Interventions:   Drug: Syntocinon®/- Spray;   Drug: Physiological serum (Sodium chloride)
Sponsor:   University Hospital, Toulouse
Completed

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