Down Syndrome



Role of Sleep Apnea in the Neuropsychological Function in Down Syndrome People


Condition:   Down Syndrome
Intervention:   Device: CPAP
Sponsor:   National Taiwan University Hospital
Completed


Correlation Between Optic Nerve Vessel Anomalies, Serum Angiogenic Factors and Renal Anomalies in Down Syndrome Children


Condition:   Down Syndrome
Interventions:   Diagnostic Test: Funduscopic examination and retinal photography;   Diagnostic Test: Serum levels of endostatin and angiogenesis factors;   Diagnostic Test: Renal and low urinary tract Doppler ultrasound;   Diagnostic Test: Urinalysis;   Diagnostic Test: Anthropometric measures and vitals signs
Sponsor:   Queen Fabiola Children's University Hospital
Not yet recruiting


The Impact of an 8-week Supported Exercise Program on Fitness and Symptoms in Adolescents With Down Syndrome


Condition:   Down Syndrome
Intervention:   Other: Exercise
Sponsor:   Boston Children’s Hospital
Not yet recruiting


Physiological Abnormalities Associated With Down Syndrome


Condition:   Down Syndrome
Intervention:  
Sponsors:   University of Arkansas;   Down Syndrome Research Foundation;   Arkansas Children Research Institute
Not yet recruiting


Effects of Karate in Adolescents With Down Syndrome


Condition:   Down Syndrome
Intervention:   Other: PKSA karate class
Sponsors:   University of Michigan;   Down Syndrome Association of Toledo
Recruiting


Assessing the Feasibility of the Use of Visual Aids in Patient Education in Adults With Down Syndrome (DS)


Condition:   Down Syndrome
Interventions:   Behavioral: Verbal instructions with picture diagram;   Behavioral: Verbal instructions with video of ADSC;   Behavioral: verbal instructions w. video of w/o DS;   Behavioral: verbal instructions w. video w/DS
Sponsor:   Advocate Health Care
Active, not recruiting


Performance Analysis in Down Syndrome on Mobile Phone


Condition:   Down Syndrome
Interventions:   Behavioral: Down Syndrome Group 1;   Behavioral: Down Syndrome Group 2;   Behavioral: Typical Development Group 1;   Behavioral: Typical Development Group 2
Sponsor:   University of Sao Paulo
Completed


Safety, Tolerability and Immunogenicity of ACI-24 Vaccine in Adults With Down Syndrome


Condition:   Down Syndrome
Interventions:   Biological: ACI-24 low dose;   Biological: ACI-24 high dose;   Biological: Placebo
Sponsors:   AC Immune SA;   National Institute on Aging (NIA);   Alzheimer's Disease Cooperative Study (ADCS);   LuMind Research Down Syndrome Foundation
Recruiting


A Study of RO5186582 in Down Syndrome Among Children 6 to 11 Years of Age


Condition:   Down Syndrome
Interventions:   Drug: Placebo;   Drug: RO5186582
Sponsor:   Hoffmann-La Roche
Terminated



Investigation of the Safety of Intranasal Glulisine in Down Syndrome


Condition:   Down Syndrome
Interventions:   Drug: Insulin glulisine;   Drug: Saline
Sponsor:   HealthPartners Institute
Recruiting


Comparison of Bispectral Index Values in Patients With and Without Down's Syndrome


Condition:   Down Syndrome
Intervention:   Device: monitoring BIS in both groups
Sponsor:   Milton S. Hershey Medical Center
Recruiting



A Study of RG1662 in Adults and Adolescents With Down Syndrome (CLEMATIS)


Condition:   Down Syndrome
Interventions:   Drug: Placebo;   Drug: RG1662
Sponsor:   Hoffmann-La Roche
Completed


Fluor Varnish With Silver Nanoparticles for Dental Remineralization in Patients With Trisomy 21


Condition:   Down Syndrome
Interventions:   Drug: Fluor varnish;   Drug: Fluor varnish with nanoparticles
Sponsor:   Universidad Autonoma de San Luis Potosí
Unknown status


DS-Connect {TM}: The Down Syndrome Registry


Condition:   Down Syndrome
Intervention:  
Sponsor:   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Suspended



Down Syndrome Metabolic Health Study


Conditions:   Down Syndrome;   Trisomy 21
Intervention:  
Sponsors:   Children's Hospital of Philadelphia;   National Institutes of Health (NIH);   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Recruiting


Trisomy 21 in Adulthood


Condition:   Down Syndrome
Intervention:   Genetic: karyotype
Sponsor:   University Hospital, Strasbourg, France
Recruiting


Efficacy Assessment of Systematic Treatment With Folinic Acid and Thyroid Hormone on Psychomotor Development of Down Syndrome Young Children


Condition:   Down Syndrome
Intervention:   Drug: thyroid hormone and folinic acid
Sponsors:   Institut Jerome Lejeune;   Ascopharm (CRO);   Effi-stat (CRO);   AnticipSante (CRO);   LC2 (CRO);   BIOMNIS Central laboratory;   UMR INSERM 1124;   Laboratoire de Biochimie Biologie Moléculaire Nutrition Métabolisme CHU Brabois (Unité Inserm 954)
Active, not recruiting


Natural History of Amyloid Deposition in Adults With Down Syndrome


Condition:   Down Syndrome
Intervention:  
Sponsors:   University of Pittsburgh;   National Institute on Aging (NIA)
Active, not recruiting


Parent Supported Weight Reduction in Down Syndrome


Condition:   Down Syndrome
Interventions:   Behavioral: Parent Supported Behavioral Intervention;   Behavioral: Nutrition/Activity Education (NAE)
Sponsors:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);   University of Massachusetts, Worcester
Completed


Assessment of Bone Density and Bone Turnover Markers in Patients With Down Syndrome and Comparison to the Ts65Dn Model


Condition:   Down Syndrome
Intervention:   Other: Skeletal Status Assessment of a Down Syndrome Population
Sponsor:   University of Arkansas
Completed


The Experience of Caregivers of Children With Down Syndrome


Condition:   Down Syndrome
Intervention:  
Sponsor:   National Human Genome Research Institute (NHGRI)
Completed


Evaluating The Efficacy And Safety Of Donepezil Hydrochloride (Aricept) In Treating Cognitive Dysfunction Exhibited By Children With Down Syndrome


Condition:   Down Syndrome
Interventions:   Drug: Donepezil hydrochloride;   Drug: Placebo
Sponsors:   Eisai Inc.;   Pfizer
Completed

Refine Your Search Advanced Search