Cystic Fibrosis



Pregnancies and Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:  
Sponsor:   Hospices Civils de Lyon
Active, not recruiting


Clearance of 25-hydroxyvitamin D in Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:   Drug: d6-25-hydroxyvitamin D3
Sponsors:   University of Washington;   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting


A Study to Evaluate Safety, PK and PD of FDL169 in Cystic Fibrosis Subjects


Condition:   Cystic Fibrosis
Interventions:   Drug: FDL169;   Drug: Placebo
Sponsor:   Flatley Discovery Lab LLC
Recruiting


Evaluation of Short Antibiotic Combination Courses Followed by Aerosols in Cystic Fibrosis


Condition:   Cystic Fibrosis
Interventions:   Drug: Tobi Inhalant Product;   Drug: Nebcin
Sponsor:   University Hospital, Lille
Recruiting


The Role of Oral Glutathione on Growth Parameters in Children With Cystic Fibrosis


Condition:   Cystic Fibrosis
Interventions:   Drug: Oral Glutathione;   Drug: Placebo
Sponsors:   University of Minnesota - Clinical and Translational Science Institute;   Cystic Fibrosis Foundation Therapeutics
Recruiting


Prognostic Value of Functional Exercise Test (EFX) in Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:   Other: cardiopulmonary exercise testing
Sponsor:   University Hospital, Lille
Recruiting


Study of GLPG1837 in Subjects With Cystic Fibrosis (G551D Mutation)


Condition:   Cystic Fibrosis
Interventions:   Drug: GLPG1837 dose 1;   Drug: GLPG1837 dose 2;   Drug: GLPG1837 dose 3
Sponsor:   Galapagos NV
Completed


Integrating Supportive Care in Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:   Behavioral: Supportive Care Intervention
Sponsors:   University of Pittsburgh;   Cystic Fibrosis Foundation Therapeutics
Recruiting


Safety, Pharmacokinetics and Pharmacodynamics Study of Inhaled QBW276 in Patients With Cystic Fibrosis


Condition:   Pulmonary Cystic Fibrosis
Interventions:   Other: Placebo;   Drug: QBW276
Sponsor:   Novartis Pharmaceuticals
Recruiting


Puberty in Girls Followed for Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:   Procedure: Data collection
Sponsor:   University Hospital, Toulouse
Completed


Electrical Impedance Imaging of Patients With Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:   Device: CT scan
Sponsors:   Colorado State University;   Children's Hospital Colorado;   University of Colorado, Denver
Enrolling by invitation


Observational Study of Outcomes in Cystic Fibrosis Patients With Selected Gating Mutations on a CFTR Allele (The VOCAL Study)


Condition:   Cystic Fibrosis
Intervention:   Drug: ivacaftor
Sponsor:   Vertex Pharmaceuticals Incorporated
Active, not recruiting


Evaluating High Flow Humidification Therapy in Patients With Cystic Fibrosis


Condition:   Cystic Fibrosis
Interventions:   Device: High-Flow, 20 LPM (via Optiflow cannula);   Device: Low FLow, 5 LPM (via Optiflow cannula)
Sponsor:   Virginia Commonwealth University
Recruiting


Roll-Over Study of Ivacaftor in Cystic Fibrosis Pediatric Subjects With a CF Transmembrane Conductance Regulator Gene (CFTR) Gating Mutation


Condition:   Cystic Fibrosis
Intervention:   Drug: Ivacaftor
Sponsors:   Vertex Pharmaceuticals Incorporated;   Cystic Fibrosis Foundation Therapeutics
Completed


Extrapulmonary Effects of Cystic Fibrosis on Physical Activity of Adult Patients.


Condition:   Cystic Fibrosis
Intervention:  
Sponsor:   Assistance Publique - Hôpitaux de Paris
Completed


Efficacy Study of IgY (Antibody Against Pseudomonas) in Cystic Fibrosis Patients


Condition:   Cystic Fibrosis
Interventions:   Drug: IgY;   Drug: Placebo
Sponsor:   Mukoviszidose Institut gGmbH
Completed


Inhaled Glutathione (GSH) Versus Placebo in Cystic Fibrosis


Condition:   Cystic Fibrosis
Interventions:   Drug: Inhaled Reduced Glutathione;   Drug: Physiological solution
Sponsors:   Serafino A. Marsico;   Federico II University
Unknown status


Costimulatory Molecules as Biomarkers in Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:  
Sponsor:   Oregon Health and Science University
Completed


28 Day Repeat Dose in Cystic Fibrosis Patients


Condition:   Cystic Fibrosis
Interventions:   Drug: SB656933;   Drug: Placebo
Sponsor:   GlaxoSmithKline
Completed


RhDNase and Biodistribution of PMN Serine Proteases in Cystic Fibrosis Sputum


Condition:   Cystic Fibrosis
Intervention:   Drug: Pulmozyme
Sponsor:   University Hospital, Tours
Completed


Infant Study of Inhaled Saline in Cystic Fibrosis


Condition:   Cystic Fibrosis
Interventions:   Drug: 7% Hypertonic Saline (HS);   Drug: 0.9% Isotonic Saline (IS)
Sponsors:   CF Therapeutics Development Network Coordinating Center;   Cystic Fibrosis Foundation Therapeutics;   National Heart, Lung, and Blood Institute (NHLBI)
Completed


Tolerability of Inhaled Hypertonic Saline in Infants With Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:   Drug: inhaled 7% hypertonic saline (HS)
Sponsors:   CF Therapeutics Development Network Coordinating Center;   Cystic Fibrosis Foundation Therapeutics
Completed


Absorptive Clearance in the Cystic Fibrosis Airway


Condition:   Cystic Fibrosis
Intervention:   Other: Technetium [Tc-99m] sulfur colloid and Indium [In-111] DTPA
Sponsor:   University of Pittsburgh
Completed


Macrolide Antibiotic Therapy for Patients With Cystic Fibrosis


Condition:   Cystic Fibrosis
Intervention:   Drug: Biaxin ( clarithromycin)
Sponsors:   Wake Forest University;   Abbott
Completed


Studying Patients With Cystic Fibrosis and Other Pulmonary and Pancreatic Disorders


Condition:   Cystic Fibrosis
Intervention:  
Sponsor:   National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Recruiting

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