Charcot Marie Tooth Disease

Study of ACE-083 in Patients With Charcot-Marie-Tooth Disease

Condition:   Charcot-Marie-Tooth Disease
Intervention:   Drug: ACE-083
Sponsor:   Acceleron Pharma, Inc.
Recruiting - verified April 2017

Efficacy of Keyhole Approach to Carpal Tunnel Syndrome Under Ambulatory Strategy

Conditions:   Carpal Tunnel Syndrome;   Entrapment Neuropathy
Intervention:   Procedure: keyhole approach
Sponsor:   Ivan Segura Duran
Completed - verified February 2017

Assessing Long Term Safety and Tolerability of PXT3003 in Patients With Charcot-Marie-Tooth Disease Type 1A

Condition:   Charcot-Marie-Tooth Disease, Type IA
Intervention:   Drug: PXT3003
Sponsors:   Pharnext SA;   SynteractHCR;   INC Research
Recruiting - verified April 2017

Charcot-Marie-Tooth Disease (CMT) Infant Scale (INC-6611)

Condition:   Charcot-Marie-Tooth Disease
Intervention:   Other: No intervention involved
Sponsors:   Sydney Children's Network;   University of Iowa Health Care;   Children's Hospital of Philadelphia;   University of Pennsylvania;   University of Rochester;   National Hospital of Neurology and Neurosurgery;   Dubowitz Neuromuscular Centre;   University of Miami;   Besta Neurological Institute;   Johns Hopkins University;   Vanderbilt University;   University of Washington;   Nemours Children's Hospital;   National Institutes of Health - Intramural Branch (Bethesda);   Stanford University;   Cedars-Sinai Medical Center;   Harvard/Massachusetts General Hospital;   University of Michigan;   University of Minnesota - Clinical and Translational Science Institute;   University of Utah;   University of Connecticut;   Universiteit Antwerpen
Recruiting - verified November 2016

BALTiC Study: A Feasibility Analysis of Home Based BALance Training in People With Charcot-Marie-Tooth Disease

Condition:   Charcot-Marie-Tooth Disease, Type IA
Interventions:   Behavioral: Falls management plus exercise training;   Behavioral: Falls management only
Sponsors:   University College London Hospitals;   Charcot Marie Tooth United Kingdom;   Kingston University
Not yet recruiting - verified November 2016

Health-Related Quality of Life in Cases of Cubital Tunnel Syndrome

Condition:   Cubital Tunnel Syndrome
Intervention:   Procedure: Anterior Intramuscular Transposition
Sponsor:   McMaster University
Not yet recruiting - verified January 2017

SERENDEM : MD1003 in Patients Suffering From Demyelinating Neuropathies, an Open Label Pilot Study

Conditions:   Chronic Inflammatory Demyelinating Polyneuropathy;   Peripheral Neuropathy;   Charcot-Marie-Tooth Disease;   Charcot-Marie-Tooth Disease Type 1A;   Charcot-Marie-Tooth Disease, Type IA
Intervention:   Drug: MD1003
Sponsor:   MedDay Pharmaceuticals SA
Recruiting - verified November 2016

Clinical Study of a Single Ciliopathy: Alström Syndrome

Condition:   Alström Syndrome (ALMS)
Sponsor:   University Hospital, Strasbourg, France
Recruiting - verified August 2016

Patient Reported Outcomes Measures (PROM) in Carpal Tunnel Therapies in Patients With Inherited Neuropathies

Conditions:   Carpal Tunnel Syndrome;   Charcot-Marie-Tooth Disease;   Inherited Peripheral Neuropathy
Intervention:   Other: Web-based survey
Sponsors:   University of South Florida;   National Institute of Neurological Disorders and Stroke (NINDS);   University of Rochester;   University of Iowa
Completed - verified March 2017

The Effect of ESWT for Cubital Tunnel Syndrome

Condition:   Cubital Tunnel Syndrome
Intervention:   Device: extracorporeal shock wave therapy
Sponsor:   Tri-Service General Hospital
Recruiting - verified June 2016

Lidocaine and Triamcinolone vs Saline Trigger Point Injection for Treatment of Chronic Abdominal Wall Pain

Conditions:   Chronic Abdominal Wall Pain;   Abdominal Cutaneous Nerve Entrapment Syndrome
Interventions:   Drug: Triamcinolone;   Other: Placebo;   Drug: Lidocaine
Sponsor:   Temple University
Withdrawn - verified December 2016

Low Dose Dexamethasone in Supraclavicular Blocks

Conditions:   Rheumatoid Arthritis;   Osteoarthritis;   Nerve Entrapment;   Ligament Injury
Interventions:   Drug: Control intervention (no dexamethasone);   Drug: Peri-neural Dexamethasone 1 mg;   Drug: Intravenous Dexamethasone 1 mg
Sponsor:   University of Calgary
Recruiting - verified September 2016

Infraclavicular or Supraclavicular Brachial Plexus Blocks for Elbow Surgery

Conditions:   Cubital Tunnel Syndrome;   Biceps Tendon Rupture
Interventions:   Procedure: Supraclavicular;   Procedure: Infraclavicular
Sponsor:   Lawson Health Research Institute
Completed - verified February 2017

Ulipristal Acetate In Disease Charcot-Marie-Tooth Type of 1A

Condition:   CMT1A
Interventions:   Drug: EllaOne;   Drug: EllaOne placebo
Sponsor:   University Hospital, Strasbourg, France
Recruiting - verified May 2017

Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients (PLEO-CMT)

Condition:   Charcot-Marie-Tooth Disease Type 1A
Interventions:   Drug: PXT3003 dose 1;   Drug: PXT3003 dose 2;   Drug: placebo
Sponsor:   Pharnext SA
Active, not recruiting - verified January 2017

Mexiletine for Muscle Cramps in Charcot Marie Tooth Disease

Condition:   Charcot Marie Tooth Disease
Interventions:   Other: Placebo;   Drug: Mexiletine
Sponsor:   University of Rochester
Completed - verified March 2017

Electrical Nerve Stimulation of the Ulnar Nerve

Condition:   Cubital Tunnel Syndrome
Intervention:   Device: Ulnar Nerve Stimulation
Sponsor:   University of Chicago
Withdrawn - verified April 2017

Prospective Comparison of Techniques for Cubital Tunnel Release

Condition:   Cubital Tunnel Syndrome
Intervention:   Procedure: Cubital tunnel release
Sponsor:   University of Pittsburgh
Enrolling by invitation - verified October 2016

Intrathecal Administration of scAAV9/JeT-GAN for the Treatment of Giant Axonal Neuropathy

Conditions:   Giant Axonal Neuropathy;   Gene Transfer
Intervention:   Drug: Intrathecal Delivery of scAAV9/JeT-GAN
Sponsor:   National Institute of Neurological Disorders and Stroke (NINDS)
Recruiting - verified March 28, 2017

Suprascapular Neuropathy in the Setting of Rotator Cuff Tears: Results of Arthroscopic Treatment

Conditions:   Entrapment Neuropathy;   Rotator Cuff Tear
Intervention:   Procedure: Dissection of the superior transverse scapular ligament
Sponsor:   Aristotle University Of Thessaloniki
Recruiting - verified March 2017

Chemotherapy Induced Peripheral Neuropathy. Could Physical Therapy Help Treat Symptoms?

Conditions:   Breast Cancer;   Peripheral Neuropathy, Secondary to Drugs or Chemicals
Intervention:   Other: Physical Therapy
Sponsors:   CancerCare Manitoba;   University of Manitoba
Active, not recruiting - verified May 2017

A Randomized Trial Measuring the Effect of Decision Aids on Patients' Satisfaction, Conflict of Decision-making and Clinical Outcome

Conditions:   Trapeziometacarpal Arthrosis;   Carpal Tunnel Syndrome;   Cubital Tunnel Syndrome;   Distal Radius Fractures;   Trigger Finger
Intervention:   Behavioral: Decision Aid
Sponsor:   Massachusetts General Hospital
Enrolling by invitation - verified December 2016

Giant Axonal Neuropathy Natural History Study

Condition:   Giant Axonal Neuropathy
Sponsors:   Columbia University;   University of North Carolina, Chapel Hill
Terminated - verified January 2017

Phase II, Randomized, Placebo-controlled Trial in Patients With Charcot-marie-tooth Disease Type 1A

Conditions:   Charcot-Marie-Tooth Disease;   Hereditary Neuropathy With Liability to Pressure Palsies;   Genetic Disorders;   Tooth Disorders
Interventions:   Drug: PXT3003 Low dose;   Drug: PXT3003 Intermediate Dose;   Drug: PXT3003 High Dose;   Other: Placebo
Sponsor:   Pharnext SA
Completed - verified July 2011

Simple Decompression Versus Anterior Transposition of the Ulnar Nerve

Conditions:   Humeral Fractures;   Ulnar Nerve Compression
Interventions:   Procedure: Simple decompression;   Procedure: anterior subcutaneous transposition
Sponsor:   St. Michael's Hospital, Toronto
Active, not recruiting - verified October 2016

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