Angelman Syndrome

Single Dose Pharmacokinetic (PK) Study

Conditions:   Angelman Syndrome;   Fragile X Syndrome
Intervention:   Drug: OV101
Sponsor:   Ovid Therapeutics Inc.
Recruiting - verified April 2017

A Study in Adults With Angelman Syndrome

Condition:   Angelman Syndrome
Interventions:   Drug: OV101 Regimen 1;   Drug: OV101 regimen 2;   Other: Placebo
Sponsor:   Ovid Therapeutics Inc.
Recruiting - verified May 2017

Efficacy and Safety of Circadin® in the Treatment of Sleep Disturbances in Children With Neurodevelopment Disabilities

Condition:   Sleep Disorders
Interventions:   Drug: Circadin 2/5/10 mg;   Drug: Placebo
Sponsor:   Neurim Pharmaceuticals Ltd.
Active, not recruiting - verified July 2016

A Trial of Levodopa in Angelman Syndrome

Condition:   Angelman Syndrome
Interventions:   Drug: Levodopa;   Drug: Placebo Oral Capsule
Sponsors:   Wen-Hann Tan;   Rady Children's Hospital, San Diego;   University of California, San Francisco;   Baylor College of Medicine;   Vanderbilt University;   Greenwood Genetic Center;   Children's Hospital Medical Center, Cincinnati;   Angelman Syndrome Foundation, Inc.
Completed - verified November 2016

Study on Tolerability of Levodopa/Carbidopa in Children With Angelman Syndrome

Condition:   Angelman Syndrome
Intervention:   Drug: Levodopa/Carbidopa (4:1)
Sponsor:   Boston Children’s Hospital
Completed - verified September 2016

Characterization of Angelman Syndrome

Condition:   Angelman Syndrome
Sponsors:   University of California, San Diego;   Rady Children's Hospital, San Diego;   Texas Children's Hospital;   Boston Children’s Hospital;   Greenwood Genetic Center;   Children's Hospital Medical Center, Cincinnati;   National Center for Research Resources (NCRR)
Active, not recruiting - verified November 2016

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