Macular Degeneration (AMD)



Dark Adaptation in Participants With Age-Related Macular Degeneration


Condition:   Age-Related Macular Degeneration
Intervention:  
Sponsor:   National Eye Institute (NEI)
Enrolling by invitation


Age-Related Macular Degeneration, Scotopic Dysfunction, and Driving Performance in a Simulator


Condition:   Age-related Macular Degeneration
Intervention:  
Sponsor:   University of Alabama at Birmingham
Not yet recruiting


Five-year Incidence of Age-related Macular Degeneration in the Central Region of Portugal


Condition:   Age-Related Macular Degeneration
Intervention:  
Sponsor:   Association for Innovation and Biomedical Research on Light and Image
Recruiting


Evaluation of Visual Function and Driving Health Using Ocusweep in Patients Suffering From Wet Age-related Macular Degeneration


Condition:   Macular Degeneration
Intervention:   Device: Ocusweep system
Sponsor:   Turku University Hospital
Enrolling by invitation


Evaluation the Pharmacokinetics, Safety, Tolerability of TK001 in Patients With Neovascular Age-related Macular Degeneration


Condition:   Neovascular Age-related Macular Degeneration
Intervention:   Biological: TK001
Sponsor:   Jiangsu T-Mab Biopharma Co.,Ltd
Recruiting


Managing Neovascular (Known as "Wet") Age-related Macular Degeneration Over 2 Years Using Different Treatment Schedules of 2 mg Intravitreal Aflibercept Injected in the Eye


Condition:   Macular Degeneration
Intervention:   Drug: Eylea (Intravitreal Aflibercept, VEGF Trap-Eye, BAY86-5321)
Sponsor:   Bayer
Recruiting


A Phase I/II Safety, Tolerability, Immunogenicity, and Bioactivity Study of DE-122 Injectable Solution for Refractory Exudative Age-related Macular Degeneration


Condition:   Age-Related Macular Degeneration
Intervention:   Drug: DE-122
Sponsor:   Santen Inc.
Completed


Caregiver Burden of Wet Age-related Macular Degeneration (wAMD) in Japan


Condition:   Wet Macular Degeneration
Intervention:   Drug: Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)
Sponsors:   Bayer;   Regeneron Pharmaceuticals
Completed


Efficacy and Safety of Two Different Aflibercept Regimens in Subjects With Neovascular Age-related Macular Degeneration (nAMD)


Condition:   Macular Degeneration
Intervention:   Drug: Aflibercept (Eylea, VEGF Trap-Eye, BAY86-5321)
Sponsors:   Bayer;   Regeneron Pharmaceuticals
Recruiting


A Safety and Efficacy Study of DE-120 Injectable Solution for Age-related Macular Degeneration


Condition:   Age-Related Macular Degeneration
Interventions:   Drug: DE-120;   Drug: Aflibercept
Sponsor:   Santen Inc.
Completed


A Phase I/II Safety Study of DE-120 Injectable Solution for Age-related Macular Degeneration


Condition:   Age-Related Macular Degeneration
Intervention:   Drug: DE-120
Sponsor:   Santen Inc.
Completed



Proton Radiation Therapy for Macular Degeneration


Condition:   Age-Related Macular Degeneration
Intervention:   Radiation: Proton radiation
Sponsor:   University of Florida
Active, not recruiting


Age-related Macular Degeneration (AMD) in the Vitamin D and Omega-3 Trial (VITAL)


Condition:   Age-related Macular Degeneration
Interventions:   Drug: Omega-3 fatty acids (fish oil);   Dietary Supplement: Vitamin D3;   Dietary Supplement: Vitamin D3 placebo;   Dietary Supplement: Fish oil placebo
Sponsors:   Brigham and Women's Hospital;   National Eye Institute (NEI)
Active, not recruiting


Repeated Eye Injections of Aflibercept for Treatment of Wet Age Related Macular Degeneration


Conditions:   Age-Related Macular Degeneration;   Macular Degeneration
Interventions:   Drug: Intravitreal Aflibercept Injection More;   Drug: Intravitreal Aflibercept Injection Less
Sponsors:   MidAtlantic Retina;   Regeneron Pharmaceuticals
Completed


Effect of Omega-3-fatty Acids on Blood Levels Omega-3 Fatty Acids in Patients With Age-related Macular Degeneration


Condition:   Macular Degeneration
Intervention:   Dietary Supplement: Omega-3 fatty acid
Sponsors:   Wills Eye;   Physician Recommended Nutriceuticals
Completed


Intravitreal Bone Marrow-Derived Stem Cells in Patients With Macular Degeneration


Condition:   Age Related Macular Degeneration and Stargartd
Intervention:   Other: intravitreal injection of autologous bone marrow stem cells
Sponsor:   University of Sao Paulo
Completed


12 Week Patient Study in Neovascular Age-related Macular Degeneration (AMD)


Condition:   Macular Degeneration
Intervention:   Drug: pazopanib eye drops
Sponsor:   GlaxoSmithKline
Terminated


Study of WA-NG Telescope Prosthesis in Patients With End-stage Age-related Macular Degeneration


Condition:   Age Related Macular Degeneration
Interventions:   Device: Telescope prosthesis;   Device: WA-NG Telescope Prothesis
Sponsor:   VisionCare, Inc.
Withdrawn


Study of Dark Adaptation in Age-Related Macular Degeneration


Condition:   Age-Related Macular Degeneration
Intervention:  
Sponsor:   National Eye Institute (NEI)
Recruiting


Phase I Dose Escalation Safety Study of RetinoStat in Advanced Age-Related Macular Degeneration (AMD)


Condition:   Age Related Macular Degeneration
Intervention:   Drug: Subretinally injected RetinoStat
Sponsor:   Oxford BioMedica
Completed


Dose Ranging Study of Pazopanib to Treat Neovascular Age-Related Macular Degeneration


Condition:   Macular Degeneration
Interventions:   Drug: pazopanib eye drops;   Drug: placebo;   Biological: ranibizumab intravitreal injection
Sponsor:   GlaxoSmithKline
Completed


High Speed Indocyanine Green Angiography Findings in Ranibizumab Treatment for Wet Age-related Macular Degeneration


Condition:   Macular Degeneration
Intervention:  
Sponsor:   National Eye Institute (NEI)
Completed


Fundus Autofluorescence Imaging in Age-related Macular Degeneration Using Confocal Scanning Laser Ophthalmoscopy


Condition:   Age-related Macular Degeneration
Intervention:  
Sponsor:   University Hospital, Bonn
Active, not recruiting


Triamcinolone Acetonide Plus Laser Therapy to Treat Age-Related Macular Degeneration


Condition:   Macular Degeneration
Interventions:   Drug: TAC-PF;   Drug: Triamcinolone Acetonide
Sponsor:   National Eye Institute (NEI)
Completed

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